PDB: 1955 件ウェブページステータス検索Chemie searchBIRD

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8BF5	Early transcription elongation state of influenza A/H7N9 polymerase stalled with incoming GTP analogue 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-24 公開日 2022-12-28 最終更新日 2023-02-15 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8BEK	Early transcription elongation state of influenza A/H7N9 backtracked polymerase with singly incoporated T1106 at the U +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-21 公開日 2022-12-28 最終更新日 2023-02-15 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8BE0	Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-20 公開日 2022-12-28 最終更新日 2023-02-15 実験手法 ELECTRON MICROSCOPY (2.34 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8BDR	Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-19 公開日 2022-12-28 最終更新日 2023-02-15 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8BCR	DENV3 Methyltransferase in complexed with AT-9010 and SAH 分子名称: Genome polyprotein, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Gauffre, P, Fattorini, V, Canard, B, Ferron, F. 登録日 2022-10-17 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5. Antiviral Res., 212, 2023
8H69	Cryo-EM structure of influenza RNA polymerase 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ... 著者 Li, H, Wu, Y, Liang, H, Liu, Y. 登録日 2022-10-16 公開日 2023-06-28 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles. Nat.Struct.Mol.Biol., 30, 2023
8B8V	Crystal structure of the Rabies virus RNA free nucleoprotein- phosphoprotein complex 分子名称: DI(HYDROXYETHYL)ETHER, Nucleoprotein, Phosphoprotein 著者 Gerard, F.C.A, Jamin, M, Bourhis, J.M. 登録日 2022-10-05 公開日 2023-03-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module. Viruses, 14, 2022
8H0W	RNA polymerase II transcribing a chromatosome (type II) 分子名称: DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2022-09-30 公開日 2022-12-07 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1. Nat Commun, 13, 2022
8H0V	RNA polymerase II transcribing a chromatosome (type I) 分子名称: DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H. 登録日 2022-09-30 公開日 2022-12-07 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1. Nat Commun, 13, 2022
8GZP	Cryo-EM structure of the NS5-SLA complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... 著者 Osawa, T, Ehara, H, Sekine, S. 登録日 2022-09-27 公開日 2023-08-02 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures of dengue virus RNA replicase complexes. Mol.Cell, 83, 2023
8GZQ	Cryo-EM structure of the NS5-NS3-SLA complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, Genome polyprotein, RNA, ... 著者 Osawa, T, Ehara, H, Sekine, S. 登録日 2022-09-27 公開日 2023-08-02 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of dengue virus RNA replicase complexes. Mol.Cell, 83, 2023
8GZR	Cryo-EM structure of the the NS5-NS3 RNA-elongation complex 分子名称: CYTIDINE-5'-DIPHOSPHATE, Genome polyprotein, MANGANESE (II) ION, ... 著者 Osawa, T, Ehara, H, Sekine, S. 登録日 2022-09-27 公開日 2023-08-02 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structures of dengue virus RNA replicase complexes. Mol.Cell, 83, 2023
8B51	Usutu virus methyltransferase domain in complex with sinefungin 分子名称: GLYCEROL, GLYCINE, RNA-directed RNA polymerase NS5, ... 著者 Ferrero, D.S, Albentosa Gonzalez, L, Mas, A, Verdaguer, N. 登録日 2022-09-21 公開日 2023-10-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure and function of the NS5 methyltransferase domain from Usutu virus. Antiviral Res., 208, 2022
8GY6	Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding 分子名称: Gossypol, Non-structural protein 7, Non-structural protein 8, ... 著者 Wang, W, Ren, M, Li, F. 登録日 2022-09-21 公開日 2023-11-01 実験手法 ELECTRON MICROSCOPY 主引用文献 Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding To Be Published
8B52	Usutu virus methyltransferase domain in complex with sinefungin 分子名称: GLYCEROL, Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Ferrero, D.S, Albentosa Gonzalez, L, Mas, A, Verdaguer, N. 登録日 2022-09-21 公開日 2023-10-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structure and function of the NS5 methyltransferase domain from Usutu virus. Antiviral Res., 208, 2022
8GWO	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: Helicase, Non-structural protein 7, Non-structural protein 8, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-11-30 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWF	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.Y, Huang, Y.C, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.39 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWG	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWN	A mechanism for SARS-CoV-2 RNA capping and its inhibitor of AT-527 分子名称: Helicase, Non-structural protein 7, Non-structural protein 8, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWI	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2022-12-14 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWM	SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP 分子名称: 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate), Helicase, Non-structural protein 7, ... 著者 Yan, L.M, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWK	SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP 分子名称: Helicase, MAGNESIUM ION, Non-structural protein 7, ... 著者 Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-17 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.72 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWE	SARS-CoV-2 E-RTC complex with RNA-nsp9 and GMPPNP 分子名称: Helicase nsp13, MAGNESIUM ION, Non-structural protein 8, ... 著者 Yan, L.M, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-16 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.66 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GWB	SARS-CoV-2 E-RTC complex with RNA-nsp9 分子名称: Helicase, MANGANESE (II) ION, Non-structural protein 7, ... 著者 Yan, L.M, Rao, Z.H, Lou, Z.Y. 登録日 2022-09-16 公開日 2022-12-07 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.75 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
8GW1	A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors 分子名称: Helicase, MANGANESE (II) ION, Non-structural protein 7, ... 著者 Yan, L, Rao, Z, Lou, Z. 登録日 2022-09-16 公開日 2023-10-25 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022

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