8ZWK
 
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9C84
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9C8J
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9C8S
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9C8M
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9C8L
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9C8O
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9C8P
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9C81
 | | X-ray crystal structure of AmpC beta-lactamase with inhibitor | | 分子名称: | (2R)-2-phenoxy-3-{[(1S,2S,4S)-spiro[bicyclo[2.2.1]heptane-7,1'-cyclopropane]-2-carbonyl]amino}propanoic acid, AmpC Beta-lactamase | | 著者 | Liu, F, Shoichet, B.K, Bassim, V. | | 登録日 | 2024-06-11 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Improved correlations with score, hit-rate, and affinity as docking library and testing scale increase
To Be Published
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9C7V
 | | Structure of the human BOS:human EMC complex in GDN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BOS complex subunit NOMO2, ... | | 著者 | Nguyen, V.N, Tomaleri, G.P, Voorhees, R.M. | | 登録日 | 2024-06-11 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins.
Mol.Cell, 84, 2024
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9C83
 | | X-ray crystal structure of AmpC beta-lactamase with inhibitor | | 分子名称: | AmpC Beta-lactamase, N-[(3M)-3-(5-chloro-1,2,3-thiadiazol-4-yl)phenyl]-5-methyl-3-oxo-2,3-dihydro-1,2-oxazole-4-sulfonamide | | 著者 | Liu, F, Shoichet, B.K. | | 登録日 | 2024-06-11 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Improved correlations with score, hit-rate, and affinity as docking library and testing scale increase
To Be Published
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9C74
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8ZUH
 | | Crystal structure of bovine Fbs2/Skp1/Man3GlcNAc2 complex | | 分子名称: | F-box only protein 6, S-phase kinase-associated protein 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Satoh, T, Mizushima, T, Yagi, H, Kato, R, Kato, K. | | 登録日 | 2024-06-09 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of sugar recognition by SCF FBS2 ubiquitin ligase involved in NGLY1 deficiency.
Febs Lett., 598, 2024
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9C6P
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9C6M
 | | Yasminevirus c12orf29, a 5' to 3' RNA ligase, K73M mutant | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, RNA ligase1 | | 著者 | Hu, Y, Lopez, V.A, Tagliabracci, V.S, Tomchick, D.R. | | 登録日 | 2024-06-07 | | 公開日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation
To Be Published
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9C62
 | | P400 subcomplex of the native human TIP60 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | | 登録日 | 2024-06-07 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (5.28 Å) | | 主引用文献 | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
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9C6L
 | | Yasminevirus c12orf29, a 5' to 3' RNA ligase | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, RNA ligase1, ... | | 著者 | Hu, Y, Lopez, V.A, Tagliabracci, V.S, Tomchick, D.R. | | 登録日 | 2024-06-07 | | 公開日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation
To Be Published
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9C6N
 | | ARP module of the human TIP60 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | | 登録日 | 2024-06-07 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
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9FMR
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9FMM
 | | Structure of human ACE2 in complex with a fluorinated small molecule inhibitor | | 分子名称: | (2~{S})-2-[[(2~{S})-3-[3-[(3-chloranyl-5-fluoranyl-phenyl)methyl]imidazol-4-yl]-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-4-methyl-pentanoic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Benoit, R.B, Rodrigues, M.J, Wieser, M.M. | | 登録日 | 2024-06-06 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2.
Eur J Nucl Med Mol Imaging, 2024
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9FMN
 | | Structure of Human PADI6 | | 分子名称: | Protein-arginine deiminase type-6 | | 著者 | Mouilleron, S, Walport, L, Williams, J, Marsh, A.J, Hernandez Trapero, R. | | 登録日 | 2024-06-06 | | 公開日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structural insight into the function of human peptidyl arginine deiminase 6.
Comput Struct Biotechnol J, 23, 2024
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9C5S
 | | Disulfide-linked, antiparallel p53-derived peptide dimer (CV1) | | 分子名称: | Cellular tumor antigen p53, SULFATE ION | | 著者 | Vithanage, N, Kreitler, D.K, DiGiorno, M.C, Victorio, C.G, Sawyer, N, Outlaw, V.K. | | 登録日 | 2024-06-06 | | 公開日 | 2024-06-26 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | | 主引用文献 | Structural Characterization of Disulfide-Linked p53-Derived Peptide Dimers.
Res Sq, 2024
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8ZSZ
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9C56
 | | Crystal structure of human PTPN2 in complex with allosteric inhibitor | | 分子名称: | 3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFURAN-6-SULFONIC ACID [4-(THIAZOL-2-YLSULFAMOYL)-PHENYL]-AMIDE, Tyrosine-protein phosphatase non-receptor type 2 | | 著者 | Bester, S.M, Linwood, R, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-06-05 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites.
Acta Crystallogr.,Sect.F, 80, 2024
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9C55
 | | Crystal structure of human PTPN2 in complex with active site inhibitor | | 分子名称: | 5-(3-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}PHENYL)-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 2 | | 著者 | Bester, S.M, Linwood, R, Wu, W.-I, Mou, T.-C. | | 登録日 | 2024-06-05 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites.
Acta Crystallogr.,Sect.F, 80, 2024
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