PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

---

2F3E	Crystal Structure of the Bace complex with AXQ093, a macrocyclic inhibitor 分子名称: Beta-secretase 1, {(E)-(3R,6S,9R)-3-[(1S,3R)-3-((S)-1 -BUTYLCARBAMOYL-2-METHYL-PROPYLCARB AMOYL)-1-HYDROXY-BUTYL]-6-METHYL-5, 8-DIOXO-1,11-DITHIA-4,7-DIAZA-CYCLO PENTADEC-13-EN-9-YL}-CARBAMIC ACID TERT-BUTYL ESTER 著者 Rondeau, J.-M. 登録日 2005-11-21 公開日 2006-09-05 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J.Med.Chem., 49, 2006
2F3Y	Calmodulin/IQ domain complex 分子名称: CALCIUM ION, Calmodulin, MAGNESIUM ION, ... 著者 Fallon, J.L, Quiocho, F.A. 登録日 2005-11-22 公開日 2005-12-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of Calmodulin Bound to the Hydrophobic IQ Domain of the Cardiac Ca(v)1.2 Calcium Channel. Structure, 13, 2005
2F7A	BenM effector binding domain with its effector, cis,cis-muconate 分子名称: (2Z,4Z)-HEXA-2,4-DIENEDIOIC ACID, ACETATE ION, BENZOIC ACID, ... 著者 Clark, T, Haddad, S, Ezezika, O, Neidle, E, Momany, C. 登録日 2005-11-30 公開日 2006-10-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator. J.Mol.Biol., 367, 2007
2I55	Complex of glucose-1,6-bisphosphate with phosphomannomutase from Leishmania mexicana 分子名称: 1,6-di-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, MAGNESIUM ION, ... 著者 Smith, B.J. 登録日 2006-08-24 公開日 2007-04-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of Leishmania mexicana phosphomannomutase highlights similarities with human isoforms J.Mol.Biol., 363, 2006
2HRW	Crystal Structure of Phosphonopyruvate Hydrolase 分子名称: CHLORIDE ION, Phosphonopyruvate hydrolase, SODIUM ION 著者 Chen, C.C.H, Herzberg, O. 登録日 2006-07-20 公開日 2006-10-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Kinetics of Phosphonopyruvate Hydrolase from Voriovorax sp. Pal2: New Insight into the Divergence of Catalysis within the PEP Mutase/Isocitrate Lyase Superfamily Biochemistry, 45, 2006
2HRT	Asymmetric structure of trimeric AcrB from Escherichia coli 分子名称: Acriflavine resistance protein B, CITRATE ANION 著者 Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. 登録日 2006-07-20 公開日 2006-09-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science, 313, 2006
2HUW	X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand 分子名称: Growth factor receptor-bound protein 2, N-({(1R,2R,3S)-2-(methylcarbamoyl)-3-[4-(phosphonooxy)phenyl]cyclopropyl}carbonyl)-L-valyl-L-aspartamide, PHOSPHATE ION 著者 Benfield, A.P, Martin, S.F. 登録日 2006-07-27 公開日 2006-08-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein-Ligand Interactions. Angew.Chem.Int.Ed.Engl., 45, 2006
2I6K	Crystal structure of human type I IPP isomerase complexed with a substrate analog 分子名称: ACETIC ACID, AMINOETHANOLPYROPHOSPHATE, Isopentenyl-diphosphate delta-isomerase 1, ... 著者 Zhang, C, Wei, Z, Gong, W. 登録日 2006-08-29 公開日 2007-06-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of human IPP isomerase: new insights into the catalytic mechanism J.Mol.Biol., 366, 2007
2I74	Crystal structure of mouse Peptide N-Glycanase C-terminal domain in complex with mannopentaose 分子名称: ACETATE ION, GLYCEROL, PNGase, ... 著者 Zhou, X, Zhao, G, Wang, L, Li, G, Lennarz, W.J, Schindelin, H. 登録日 2006-08-30 公開日 2006-10-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module. Proc.Natl.Acad.Sci.Usa, 103, 2006
2I7F	Sphingomonas yanoikuyae B1 ferredoxin 分子名称: CITRIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin component of dioxygenase, ... 著者 Ramaswamy, S, Brown, E.N. 登録日 2006-08-30 公開日 2007-03-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural investigations of the ferredoxin and terminal oxygenase components of the biphenyl 2,3-dioxygenase from Sphingobium yanoikuyae B1. Bmc Struct.Biol., 7, 2007
2G6W	Suicide inhibition of a-Oxamine Synthase: Structures of the Covalent Adducts of 8-Amino-7-oxonanoate Synthase with trifluoroalanine 分子名称: (4-{(E)-[(2,2-DIFLUOROETHYL)IMINO]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, 8-amino-7-oxononanoate synthase 著者 Alexeev, D. 登録日 2006-02-26 公開日 2006-04-25 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Suicide inhibition of alpha-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine. Org.Biomol.Chem., 4, 2006
2G78	Crystal Structure of the R132K:Y134F Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinoic Acid at 1.70 Angstroms Resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINOIC ACID, SODIUM ION 著者 Vaezeslami, S, Geiger, J.H. 登録日 2006-02-27 公開日 2007-04-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007
2GAK	X-ray crystal structure of murine leukocyte-type Core 2 b1,6-N-acetylglucosaminyltransferase (C2GnT-L) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, beta-1,6-N-acetylglucosaminyltransferase 著者 Pak, J.E, Rini, J.M. 登録日 2006-03-09 公開日 2006-07-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray Crystal Structure of Leukocyte Type Core 2 beta1,6-N-Acetylglucosaminyltransferase: Evidence for a covergence of metal ion independent glycosyltransferase mechanism. J.Biol.Chem., 281, 2006
2GB4	Crystal structure of Thiopurine methyltransferase (18204406) from Mus musculus at 1.35 A resolution 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, Thiopurine S-methyltransferase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-09 公開日 2006-09-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure of Thiopurine methyltransferase (18204406) from Mus musculus at 1.35 A resolution To be published
2GBT	C6A/C111A CuZn Superoxide dismutase 分子名称: COPPER (I) ION, Superoxide dismutase [Cu-Zn], ZINC ION 著者 Hornberg, A, Logan, D.T, Marklund, S.L, Oliveberg, M. 登録日 2006-03-11 公開日 2007-01-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase J.Mol.Biol., 365, 2007
2G7B	Crystal Structure of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding Protein Type II In Complex With All-Trans-Retinal At 1.18 Angstroms Resolution 分子名称: ALL-TRANS AXEROPHTHENE, Cellular retinoic acid-binding protein 2, SODIUM ION 著者 Vaezeslami, S, Geiger, J.H. 登録日 2006-02-27 公開日 2007-04-17 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007
2GFH	Crystal structure of a n-acetylneuraminic acid phosphatase (nanp) from mus musculus at 1.90 A resolution 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-21 公開日 2006-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Protein C20orf147 homolog (17391249) from Mus musculus at 1.90 A resolution To be published
2GBI	rat DPP-IV with xanthine inhibitor 4 分子名称: 2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE, Dipeptidyl peptidase 4 著者 Longenecker, K.L, Jakob, C.G, Fry, E.H, Wilk, S. 登録日 2006-03-10 公開日 2006-07-04 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal Structures of DPP-IV (CD26) from Rat Kidney Exhibit Flexible Accommodation of Peptidase-Selective Inhibitors. Biochemistry, 45, 2006
2GHS	CRYSTAL STRUCTURE OF A CALCIUM-BINDING PROTEIN, REGUCALCIN (AGR_C_1268) FROM AGROBACTERIUM TUMEFACIENS STR. C58 AT 1.55 A RESOLUTION 分子名称: 1,2-ETHANEDIOL, AGR_C_1268p, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-27 公開日 2006-04-11 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of Calcium-binding protein, regucalcin (15155668) from AGROBACTERIUM TUMEFACIENS at 1.55 A resolution To be published
2G30	beta appendage of AP2 complexed with ARH peptide 分子名称: 16-mer peptide from Low density lipoprotein receptor adapter protein 1, AP-2 complex subunit beta-1, peptide sequence AAF 著者 Edeling, M.A, Collins, B.M, Traub, L.M, Owen, D.J. 登録日 2006-02-17 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular Switches Involving the AP-2 beta2 Appendage Regulate Endocytic Cargo Selection and Clathrin Coat Assembly Dev.Cell, 10, 2006
2G0C	Structure of the RNA binding domain (residues 404-479) of the Bacillus subtilis YxiN protein 分子名称: ATP-dependent RNA helicase dbpA, SULFATE ION 著者 McKay, D.B. 登録日 2006-02-11 公開日 2006-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding of 23S rRNA has an RNA recognition motif fold. RNA, 12, 2006
2G50	The location of the allosteric amino acid binding site of muscle pyruvate kinase. 分子名称: 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ALANINE, ... 著者 Holyoak, T, Williams, R, Fenton, A.W. 登録日 2006-02-22 公開日 2006-05-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Differentiating a Ligand's Chemical Requirements for Allosteric Interactions from Those for Protein Binding. Phenylalanine Inhibition of Pyruvate Kinase. Biochemistry, 45, 2006
2GA1	Crystal structure of a duf433 member protein (ava_0674) from anabaena variabilis atcc 29413 at 2.00 A resolution 分子名称: GLYCEROL, Protein of unknown function DUF433 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-03-07 公開日 2006-03-28 最終更新日 2023-01-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of (YP_321193.1) from Anabaena variabilis ATCC 29413 at 2.00 A resolution To be published
2FEU	P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... 著者 von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. 登録日 2005-12-16 公開日 2006-03-14 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
2FJA	adenosine 5'-phosphosulfate reductase in complex with substrate 分子名称: ADENOSINE-5'-PHOSPHOSULFATE, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... 著者 Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. 登録日 2006-01-02 公開日 2006-03-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states Biochemistry, 45, 2006

<692693694695696697698699700701702703704705706707>