4INS
| THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION | 分子名称: | INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION | 著者 | Dodson, G.G, Dodson, E.J, Hodgkin, D.C, Isaacs, N.W, Vijayan, M. | 登録日 | 1989-07-10 | 公開日 | 1990-04-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The structure of 2Zn pig insulin crystals at 1.5 A resolution. Philos.Trans.R.Soc.London,Ser.B, 319, 1988
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3ZXX
| Structure of self-cleaved protease domain of PatA | 分子名称: | SUBTILISIN-LIKE PROTEIN | 著者 | Koehnke, J, Zollman, D, Vendome, J, Raab, A, Houssen, W.E, Smith, M.C, Jaspars, M, Naismith, J.H. | 登録日 | 2011-08-16 | 公開日 | 2012-08-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Discovery of New Cyanobactins from Cyanothece Pcc 7425 Defines a New Signature for Processing of Patellamides. Chembiochem, 13, 2012
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3QU8
| Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine. | 分子名称: | 4-(4-nitrobenzyl)pyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... | 著者 | Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. | 登録日 | 2011-02-23 | 公開日 | 2011-09-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. Mol.Pharmacol., 80, 2011
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4GR7
| The human W42R Gamma D-Crystallin Mutant Structure at 1.7A Resolution | 分子名称: | Gamma-crystallin D, PHOSPHATE ION | 著者 | Ji, F, Jung, J, Koharudin, L.M.I, Gronenborn, A.M. | 登録日 | 2012-08-24 | 公開日 | 2012-11-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The human W42R gamma D-crystallin mutant structure provides a link between congenital and age-related cataracts. J.Biol.Chem., 288, 2013
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3QM9
| Blackfin tuna azido-myoglobin, atomic resolution | 分子名称: | 1,2-ETHANEDIOL, AZIDE ION, Myoglobin, ... | 著者 | de Serrano, V.S, Rodriguez, M.M, Schreiter, E.R. | 登録日 | 2011-02-03 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (0.91 Å) | 主引用文献 | High Resolution Structures of Blackfin Tuna Myoglobin To be Published
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1GI1
| A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE | 分子名称: | 2-(2-HYDROXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, BETA-TRYPSIN, CALCIUM ION, ... | 著者 | Katz, B.A, Elrod, K, Luong, C, Rice, M, Mackman, R.L, Sprengeler, P.A, Spencer, J, Hatayte, J, Janc, J, Link, J, Litvak, J, Rai, R, Rice, K, Sideris, S, Verner, E, Young, W. | 登録日 | 2001-01-22 | 公開日 | 2002-01-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site. J.Mol.Biol., 307, 2001
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1GJC
| ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OF SER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS | 分子名称: | 2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE, CITRIC ACID, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | 著者 | Katz, B.A, Sprengeler, P.A, Luong, C, Verner, E, Spencer, J.R, Breitenbucher, J.G, Hui, H, McGee, D, Allen, D, Martelli, A, Mackman, R.L. | 登録日 | 2001-04-27 | 公開日 | 2002-04-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets. Chem.Biol., 8, 2001
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4IHN
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4GSO
| structure of Jararacussin-I | 分子名称: | Thrombin-like enzyme BjussuSP-1 | 著者 | Ullah, A, Souza, T.C.A.B, Zanphorlin, L.M, Mariutti, R, Sanata, S.V, Murakami, M.T, Arni, R.K. | 登録日 | 2012-08-28 | 公開日 | 2012-12-12 | 最終更新日 | 2013-01-02 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of Jararacussin-I: The highly negatively charged catalytic interface contributes to macromolecular selectivity in snake venom thrombin-like enzymes. Protein Sci., 22, 2013
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1FY3
| [G175Q]HBP, A mutant of human heparin binding protein (CAP37) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Kastrup, J.S, Linde, V, Pedersen, A.K, Stoffer, B, Iversen, L.F, Larsen, I.K, Rasmussen, P.B, Flodgaard, H.J, Bjorn, S.E. | 登録日 | 2000-09-28 | 公開日 | 2001-09-28 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Two mutants of human heparin binding protein (CAP37): toward the understanding of the nature of lipid A/LPS and BPTI binding. Proteins, 42, 2001
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3ZNF
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3ZBW
| Crystal Structure of murine Angiogenin-3 | 分子名称: | ACETIC ACID, ANGIOGENIN-3, SULFATE ION, ... | 著者 | Iyer, S, Holloway, D.E, Acharya, K.R. | 登録日 | 2012-11-13 | 公開日 | 2012-12-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Crystal Structures of Murine Angiogenin-2 and -3 - Probing 'Structure - Function' Relationships Amongst Angiogenin Homologues. FEBS J., 280, 2013
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4IMN
| Crystal structure of wild type human Lipocalin PGDS bound with PEG MME 2000 | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lipocalin-type prostaglandin-D synthase | 著者 | Lim, S.M, Chen, D, Teo, H, Roos, A, Nyman, T, Tresaugues, L, Pervushin, K, Nordlund, P. | 登録日 | 2013-01-03 | 公開日 | 2013-03-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase. J.Lipid Res., 54, 2013
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2XYE
| HIV-1 Inhibitors with a Tertiary-Alcohol-containing Transition-State Mimic and various P2 and P1 prime Substituents | 分子名称: | METHYL N-[(2S)-1-[2-[(4R)-5-[[(2S)-3,3-DIMETHYL-1-METHYLAMINO-1-OXO-BUTAN-2-YL]AMINO]-4-HYDROXY-5-OXO-4-(PHENYLMETHYL)PENTYL]-2-[(4-PHENYLPHENYL)METHYL]HYDRAZINYL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE, PROTEASE | 著者 | Ohrngren, P, Wu, X, Persson, M, Ekegren, J.K, Wallberg, H, Rosenquist, A, Samuelsson, B, Unge, T, Larhed, M. | 登録日 | 2010-11-17 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | HIV-1 Protease Inhibitors with a Tertiary Alcohol Containing Transition-State Mimic and Various P2 and P1' Substituents Med.Chem.Commun., 2, 2011
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7Z3X
| Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*T)-3'), DNA (5'-D(P*GP*TP*())-3'), ... | 著者 | Ni, X, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-03-02 | 公開日 | 2022-11-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of FIR RRM1-2 Y115F mutant bound to FUSE ssDNA To Be Published
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3QM7
| Blackfin tuna carbonmonoxy-myoglobin, atomic resolution | 分子名称: | 1,2-ETHANEDIOL, CARBON MONOXIDE, Myoglobin, ... | 著者 | de Serrano, V.S, Rodriguez, M.M, Schreiter, E.R. | 登録日 | 2011-02-03 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | High Resolution Structures of Blackfin Tuna Myoglobin To be Published
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4IGA
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1IP1
| G37A HUMAN LYSOZYME | 分子名称: | LYSOZYME C, SODIUM ION | 著者 | Takano, K, Yamagata, Y, Yutani, K. | 登録日 | 2001-04-20 | 公開日 | 2001-11-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein. Proteins, 45, 2001
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3QN8
| HIV-1 protease (mutant Q7K L33I L63I) in complex with a novel inhibitor | 分子名称: | (4aS,7aS)-1,4-bis(3-hydroxybenzyl)hexahydro-1H-pyrrolo[3,4-b]pyrazine-2,3-dione, CHLORIDE ION, Protease | 著者 | Lindemann, I, Heine, A, Klebe, G. | 登録日 | 2011-02-08 | 公開日 | 2012-02-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.382 Å) | 主引用文献 | Novel inhibitors for HIV-1 protease To be Published
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3ZG2
| Sterol 14 alpha-demethylase (CYP51) from Trypanosoma cruzi in complex with the pyridine inhibitor (S)-2-(4-chlorophenyl)-2-(pyridin-3-yl)-1- (4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)ethanone (EPL-BS1246,UDO) | 分子名称: | (S)-2-(4-chlorophenyl)-2-pyridin-3-yl-1-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethanone, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE | 著者 | Hargrove, T.Y, Wawrzak, Z, Keenan, M, Chatelain, E, Lepesheva, G.I. | 登録日 | 2012-12-14 | 公開日 | 2013-09-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Complexes of Trypanosoma Cruzi Sterol 14Alpha-Demethylase (Cyp51) with Two Pyridine-Based Drug Candidates for Chagas Disease: Structural Basis for Pathogen-Selectivity J.Biol.Chem., 288, 2013
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3QO4
| The Crystal Structure of Death Receptor 6 | 分子名称: | ACETATE ION, SULFATE ION, Tumor necrosis factor receptor superfamily member 21 | 著者 | Kuester, M, Kemmerzehl, S, Dahms, S.O, Roeser, D, Than, M.E. | 登録日 | 2011-02-09 | 公開日 | 2011-05-18 | 最終更新日 | 2012-02-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of death receptor 6 (DR6): a potential receptor of the amyloid precursor protein (APP). J.Mol.Biol., 409, 2011
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3QJC
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1IWV
| Crystal Structure Analysis of Human lysozyme at 147K. | 分子名称: | CHLORIDE ION, LYSOZYME C | 著者 | Joti, Y, Nakasako, M, Kidera, A, Go, N. | 登録日 | 2002-06-03 | 公開日 | 2002-09-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Nonlinear temperature dependence of the crystal structure of lysozyme: correlation between coordinate shifts and thermal factors. Acta Crystallogr.,Sect.D, 58, 2002
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3QOB
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3ZQR
| NMePheB25 insulin analogue crystal structure | 分子名称: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | 著者 | Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. | 登録日 | 2011-06-10 | 公開日 | 2011-08-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface. J.Biol.Chem., 286, 2011
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