PDB: 19952 件ウェブページステータス検索Chemie searchBIRD

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3SRQ	S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines 分子名称: 1-[3-(2,4-diamino-6-methylquinazolin-7-yl)phenyl]ethanone, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hilgers, M. 登録日 2011-07-07 公開日 2011-08-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg.Med.Chem.Lett., 21, 2011
3SSW	E. coli trp aporepressor 分子名称: Trp operon repressor 著者 Benoff, B, Carey, J, Berman, H.M, Lawson, C.L. 登録日 2011-07-08 公開日 2011-07-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6693 Å) 主引用文献 Environment-dependent long-range structural distortion in a temperature-sensitive point mutant. Protein Sci., 21, 2012
3STT	Crystal Structure of tomato Methylketone Synthase I Apo form 分子名称: DECANOIC ACID, Methylketone synthase I 著者 Auldridge, M.E, Austin, M.B, Noel, J.P. 登録日 2011-07-11 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato. Plant Cell, 24, 2012
3SU4	Crystal structure of NS3/4A protease variant R155K in complex with vaniprevir 分子名称: (5R,7S,10S)-10-tert-butyl-N-{(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethylcyclopropyl}-15,15-dimethyl-3,9,12-trioxo-6,7,9,10,11,12,14,15,16,17,18,19-dodecahydro-1H,5H-2,23:5,8-dimethano-4,13,2,8,11-benzodioxatriazacyclohenicosine-7(3H)-carboxamide, NS3 protease,NS4A protein, SULFATE ION, ... 著者 Schiffer, C.A, Romano, K.P. 登録日 2011-07-11 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.255 Å) 主引用文献 The Molecular Basis of Drug Resistance against Hepatitis C Virus NS3/4A Protease Inhibitors. Plos Pathog., 8, 2012
3TYB	Dihydropteroate Synthase in complex with pHBA and DHP+ 分子名称: 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, Dihydropteroate synthase, P-HYDROXYBENZOIC ACID, ... 著者 Yun, M.-K, White, S.W. 登録日 2011-09-24 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Catalysis and sulfa drug resistance in dihydropteroate synthase. Science, 335, 2012
3TZF	Crystal Structure of the Yersinia pestis Dihydropteroate Synthase with Sulfonamide Drug Complex. 分子名称: 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, 7,8-dihydropteroate synthase, MAGNESIUM ION, ... 著者 Wu, Y. 登録日 2011-09-27 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Catalysis and sulfa drug resistance in dihydropteroate synthase. Science, 335, 2012
3U7E	Crystal structure of mPNKP catalytic fragment (D170A) 分子名称: Bifunctional polynucleotide phosphatase/kinase, GLYCEROL, MAGNESIUM ION, ... 著者 Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. 登録日 2011-10-13 公開日 2011-12-14 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
3U7V	The structure of a putative Beta-galactosidase from Caulobacter crescentus CB15. 分子名称: ACETIC ACID, Beta-galactosidase 著者 Cuff, M.E, Tesar, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-10-14 公開日 2011-12-21 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of a putative Beta-galactosidase from Caulobacter crescentus CB15. TO BE PUBLISHED
3U0F	The structure of Beta-ketoacyl synthase from Brucella melitensis bound to the fragment 7-hydroxycoumarin 分子名称: 7-hydroxy-2H-chromen-2-one, Beta-ketoacyl synthase, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-09-28 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites. Proteins, 88, 2020
3U8A	Crystal structure of monomeric reversibly photoswitchable red fluorescent protein rsTagRFP in the OFF state 分子名称: Fluorescent protein rsTagRFP 著者 Pletnev, S. 登録日 2011-10-16 公開日 2012-02-22 最終更新日 2012-05-09 実験手法 X-RAY DIFFRACTION (1.783 Å) 主引用文献 A structural basis for reversible photoswitching of absorbance spectra in red fluorescent protein rsTagRFP. J.Mol.Biol., 417, 2012
3U21	Crystal structure of a Fragment of Nuclear factor related to kappa-B-binding protein (residues 370-495) (NFRKB) from Homo sapiens at 2.18 A resolution 分子名称: Nuclear factor related to kappa-B-binding protein, SODIUM ION 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology, Partnership for Stem Cell Biology (STEMCELL) 登録日 2011-09-30 公開日 2011-11-02 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Structure of a Novel Winged-Helix Like Domain from Human NFRKB Protein. Plos One, 7, 2012
3U2K	S. aureus GyrB ATPase domain in complex with a small molecule inhibitor 分子名称: 2-chloro-6-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)pyridine-4-carboxamide, DNA gyrase subunit B, MAGNESIUM ION 著者 Boriack-Sjodin, P.A, Prince, D.B, Eakin, A.E, Sherer, B.A. 登録日 2011-10-03 公開日 2012-01-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. Antimicrob.Agents Chemother., 56, 2012
3U3D	Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine 分子名称: GLYCEROL, Transcriptional regulatory protein sir2 homologue, ZINC ION, ... 著者 Zhou, Y, Hao, Q. 登録日 2011-10-05 公開日 2011-11-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl Lysine Acs Chem.Biol., 2011
3U9X	Covalent attachment of pyridoxal-phosphate derivatives to 14-3-3 proteins 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. 登録日 2011-10-20 公開日 2012-05-09 最終更新日 2012-05-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Covalent attachment of pyridoxal-phosphate derivatives to 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 109, 2012
3U3N	Crystal structure of tablysin-15 分子名称: CITRIC ACID, PALMITIC ACID, PRASEODYMIUM ION, ... 著者 Andersen, J.F. 登録日 2011-10-06 公開日 2012-02-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain. J.Biol.Chem., 287, 2012
3TI0	Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddGTP-dC in Closed Conformation 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*C*AP*TP*CP*CP*GP*AP*GP*TP*CP*AP*GP*G)-3', 5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3', ... 著者 Wang, W, Beese, L.S. 登録日 2011-08-19 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis. Proc.Natl.Acad.Sci.USA, 108, 2011
3U47	Human Carbonic Anhydrase II V143L 分子名称: Carbonic anhydrase 2, GLYCEROL, ZINC ION 著者 West, D, Mckenna, R. 登録日 2011-10-07 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural modification of the hydrophobic pocket of Human Carbonic Anhydrase II To be Published
3U7F	Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp) 分子名称: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... 著者 Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. 登録日 2011-10-13 公開日 2011-12-14 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
3TL4	Crystal Structure of the tRNA Binding Domain of Glutaminyl-tRNA Synthetase from Saccharomyces cerevisiae 分子名称: Glutaminyl-tRNA synthetase 著者 Grant, T.D, Snell, E.H. 登録日 2011-08-29 公開日 2011-11-30 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase. Nucleic Acids Res., 40, 2012
3TME	Crystal structure of Staphylococcal nuclease variant Delta+NVIAGLA V23E at cryogenic temperature 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Robinson, A.C, Schlessman, J.L, Heroux, A, Garcia-Moreno E, B. 登録日 2011-08-31 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of Staphylococcal nuclease variant Delta+NVIAGLA V23E at cryogenic temperature To be Published
3TN4	Crystal structure of GkaP mutant G209D from Geobacillus kaustophilus HTA426 分子名称: COBALT (II) ION, Phosphotriesterase 著者 An, J, Zhang, Z, Zhang, Y, Feng, Y, Wu, G. 登録日 2011-09-01 公開日 2012-09-19 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Engineering a thermostable lactonase for enhanced phosphotriesterase activity against organophosphate pesticides to be published
3TP6	Crystal structure of Staphylococcal nuclease variant Delta+PHS L36E/L103K at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Robinson, A.C, Schlessman, J.L, Garcia-Moreno E, B. 登録日 2011-09-07 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Staphylococcal nuclease variant Delta+PHS L36E/L103K at cryogenic temperature To be Published
3TPA	Structure of HbpA2 from Haemophilus parasuis 分子名称: Heme-binding protein A 著者 Vergauwen, B, Van der Meeren, R, Dansercoer, A, Savvides, S.N. 登録日 2011-09-07 公開日 2011-11-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.0001 Å) 主引用文献 Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins. Bmc Biochem., 12, 2011
3TPQ	Crystal structure of wild-type MAL RPEL domain in complex with five G-actins 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
3TR0	Structure of guanylate kinase (gmk) from Coxiella burnetii 分子名称: GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, SULFATE ION 著者 Cheung, J, Franklin, M, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015

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