PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

---

8UNO	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class D) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNT	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class I) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
4XFG	cysteine dioxygenase variant - C93A at pH 6.2 with cysteine 分子名称: CHLORIDE ION, CYSTEINE, Cysteine dioxygenase type 1, ... 著者 Driggers, C.M, Karplus, P.A. 登録日 2014-12-26 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.401 Å) 主引用文献 Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
8UNM	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class B) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNY	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class N) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNQ	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class F) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
8UNV	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class K) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
7N14	Crystal structure of 4-(1H-1,2,4-triazol-1-yl)benzoic acid-bound CYP199A4 分子名称: 4-(1H-1,2,4-triazol-1-yl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bruning, J.B, Bell, S.G. 登録日 2021-05-26 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.537 Å) 主引用文献 To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme. Inorg.Chem., 61, 2022
4XHB	Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with pentanediol and CHES 分子名称: (1R,2S)-cyclopentane-1,2-diol, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sialidase B 著者 Brear, P. 登録日 2015-01-05 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
8UNZ	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class O) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
4XJ2	FerA - NADH:FMN oxidoreductase from Paracoccus denitrificans in complex with FMN 分子名称: FLAVIN MONONUCLEOTIDE, Flavin reductase domain protein, FMN-binding protein 著者 Sedlacek, V, Klumpler, T, Marek, J, Kucera, I. 登録日 2015-01-08 公開日 2016-01-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biochemical properties and crystal structure of the flavin reductase FerA from Paracoccus denitrificans. Microbiol. Res., 188-189, 2016
4XEN	High pressure protein crystallography of hen egg white lysozyme in complex with Tetra-N-acetylchitotetraose at 920 MPa 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ... 著者 Yamada, H, Watanabe, N, Nagae, T. 登録日 2014-12-24 公開日 2015-04-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 High-pressure protein crystallography of hen egg-white lysozyme Acta Crystallogr.,Sect.D, 71, 2015
8U1S	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-393 heavy chain, ... 著者 Ferguson, J.A, Raghavan, S.S.R, Ward, A.B. 登録日 2023-09-02 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published
4XF3	cysteine dioxygenase variant - Y157F at pH 8.0 with cysteine and dithionite 分子名称: CYSTEINE, Cysteine dioxygenase type 1, FE (III) ION 著者 Driggers, C.M, Karplus, P.A. 登録日 2014-12-25 公開日 2016-04-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
8UO3	CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class S) 分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Papasergi-Scott, M.M, Skiniotis, G. 登録日 2023-10-19 公開日 2024-03-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Time-resolved cryo-EM of G-protein activation by a GPCR. Nature, 629, 2024
4XFC	cysteine dioxygenase variant - Y157F at pH 6.2 unliganded 分子名称: CHLORIDE ION, Cysteine dioxygenase type 1, FE (III) ION 著者 Driggers, C.M, Karplus, P.A. 登録日 2014-12-26 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.351 Å) 主引用文献 Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
7N40	Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex 分子名称: Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog 著者 Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. 登録日 2021-06-02 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes. Nat Commun, 13, 2022
6SCQ	Cell Division Protein SepF in complex with C-terminal domain of FtsZ 分子名称: Cell division protein SepF 著者 Sogues, A, Wehenkel, A.M, Alzari, P.M. 登録日 2019-07-25 公開日 2020-03-11 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum. Nat Commun, 11, 2020
6SCS	Cell Division Protein SepF in complex with C-terminal domain of FtsZ 分子名称: Cell division protein FtsZ, Cell division protein SepF, MAGNESIUM ION 著者 Sogues, A, Wehenkel, A.M, Alzari, P.M. 登録日 2019-07-25 公開日 2020-03-11 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum. Nat Commun, 11, 2020
7N3L	Co-complex CYP46A1 with 0420 (compound 6) 分子名称: 1,2-ETHANEDIOL, Cholesterol 24-hydroxylase, GLYCEROL, ... 著者 Lane, W, Yano, J. 登録日 2021-06-01 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.631 Å) 主引用文献 Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors. J.Med.Chem., 65, 2022
7N3M	Co-complex CYP46A1 with 0431 (compound 17) 分子名称: Cholesterol 24-hydroxylase, N,N-dimethyl-1-[4-(4-methyl-1H-pyrazol-1-yl)pyridin-3-yl]piperidine-4-carboxamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Lane, W, Yano, J. 登録日 2021-06-01 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Discovery of Novel 3-Piperidinyl Pyridine Derivatives as Highly Potent and Selective Cholesterol 24-Hydroxylase (CH24H) Inhibitors. J.Med.Chem., 65, 2022
8U1Q	A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-2D10 heavy chain, ... 著者 Ferguson, J.A, Oeverdieck, S, Ward, A.B. 登録日 2023-09-01 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.36 Å) 主引用文献 A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface To Be Published
4XAR	mGluR2 ECD and mGluR3 ECD complex with ligands 分子名称: (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, IODIDE ION, Metabotropic glutamate receptor 3 著者 Clawson, D.K. 登録日 2014-12-15 公開日 2015-02-11 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures. J.Med.Chem., 58, 2015
4XBR	In cellulo Crystal Structure of PAK4 in complex with Inka 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein FAM212A,Serine/threonine-protein kinase PAK 4 著者 Baskaran, Y, Ang, K.C, Anekal, P.V, Chan, W.L, Grimes, J.M, Manser, E, Robinson, R.C. 登録日 2014-12-17 公開日 2015-12-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1 Nat Commun, 6, 2015
1Z7C	Crystal Structure of Human Placental Lactogen 分子名称: Chorionic somatomammotropin hormone 著者 Walsh, S.T.R, Kossiakoff, A.A. 登録日 2005-03-24 公開日 2006-03-07 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure and Site 1 Binding Energetics of Human Placental Lactogen. J.Mol.Biol., 358, 2006

<639640641642643644645646647648649650651652653654>