PDB: 19952 件ウェブページステータス検索Chemie searchBIRD

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3S7Y	Crystal structure of mmNAGS in Space Group P3121 at 4.3 A resolution 分子名称: N-acetylglutamate kinase / N-acetylglutamate synthase 著者 Shi, D, Li, Y, Cabrera-Luque, J, Jin, Z, Yu, X, Allewell, N.M, Tuchman, M. 登録日 2011-05-27 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.3077 Å) 主引用文献 A Novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris. Plos One, 6, 2011
3SN1	Crystal structure of putative L-alanine-DL-glutamate epimerase from Burkholderia xenovorans strain LB400 bound to magnesium and tartrate 分子名称: CHLORIDE ION, D(-)-TARTARIC ACID, MAGNESIUM ION, ... 著者 Bonanno, J.B, Patskovsky, Y, Toro, R, Dickey, M, Bain, K.T, Wu, B, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2011-06-28 公開日 2011-07-27 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of putative L-alanine-DL-glutamate epimerase from Burkholderia xenovorans strain LB400 bound to magnesium and tartrate To be Published
3S8Q	Crystal structure of the R-M controller protein C.Esp1396I OL operator complex 分子名称: DNA (5'-D(*AP*TP*GP*TP*GP*AP*CP*TP*TP*AP*TP*AP*GP*TP*CP*CP*GP*TP*G)-3'), DNA (5'-D(*TP*CP*AP*CP*GP*GP*AP*CP*TP*AP*TP*AP*AP*GP*TP*CP*AP*CP*A)-3'), R-M CONTROLLER PROTEIN 著者 McGeehan, J.E, Ball, N.J, Streeter, S.D, Thresh, S.-J, Kneale, G.G. 登録日 2011-05-30 公開日 2012-01-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Recognition of dual symmetry by the controller protein C.Esp1396I based on the structure of the transcriptional activation complex. Nucleic Acids Res., 40, 2012
3S94	Crystal structure of LRP6-E1E2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Low-density lipoprotein receptor-related protein 6 著者 Cheng, Z, Xu, W. 登録日 2011-05-31 公開日 2011-11-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of the extracellular domain of LRP6 and its complex with DKK1. Nat.Struct.Mol.Biol., 18, 2011
3S86	Crystal Structure of TM0159 with bound IMP 分子名称: INOSINIC ACID, Nucleoside-triphosphatase, SULFATE ION 著者 Sommerhalter, M, Smith, C, Awwad, K, Desai, A. 登録日 2011-05-27 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and functional characterization of a noncanonical nucleoside triphosphate pyrophosphatase from Thermotoga maritima. Acta Crystallogr.,Sect.D, 69, 2013
3S8X	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 4-{[(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-05-31 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SAP	Crystal structure of human carbonic anhydrase isozyme II with 4-{[(5-butyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-{[(5-butylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-03 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SAX	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(5-ethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(5-ethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-03 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SA7	Crystal structure of wild-type HIV-1 protease in complex with AF55 分子名称: N~2~-acetyl-N-[(2S,3R)-4-{(1,3-benzothiazol-6-ylsulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-L-leucinamide, PHOSPHATE ION, Protease 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SAF	Crystal structure of the human RRP6 catalytic domain with D313N mutation in the active site 分子名称: Exosome component 10, MAGNESIUM ION, YTTRIUM (III) ION 著者 Januszyk, K, Liu, Q, Lima, C.D. 登録日 2011-06-02 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Activities of human RRP6 and structure of the human RRP6 catalytic domain. Rna, 17, 2011
3SBJ	MutM slanted complex 7 分子名称: 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*AP*GP*G)-3', 5'-D(P*CP*CP*TP*GP*GP*TP*(CX)P*TP*AP*CP*C)-3', Formamidopyrimidine-DNA glycosylase, ... 著者 Sung, R.J, Zhang, M, Verdine, G.L. 登録日 2011-06-05 公開日 2012-01-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
3SBY	Crystal Structure of SeMet-Substituted Apo-MMACHC (1-244), a human B12 processing enzyme 分子名称: Methylmalonic aciduria and homocystinuria type C protein 著者 Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. 登録日 2011-06-06 公開日 2011-06-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural basis of multifunctionality in a vitamin B12-processing enzyme. J.Biol.Chem., 286, 2011
3SC3	Crystal structure of a Putative DNA replication regulator Hda (Sama_1916) from SHEWANELLA AMAZONENSIS SB2B at 3.00 A resolution 分子名称: Putative DNA replication regulator Hda, SULFATE ION 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-06 公開日 2011-07-13 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.001 Å) 主引用文献 Crystal structure of a Putative DNA replication regulator Hda (Sama_1916) from SHEWANELLA AMAZONENSIS SB2B at 3.00 A resolution To be published
3SD0	Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice 分子名称: 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glycogen synthase kinase-3 beta 著者 Mesecar, A.M, Walters, R.L. 登録日 2011-06-08 公開日 2011-08-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice To be Published
3SDK	Structure of yeast 20S open-gate proteasome with Compound 34 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-[(2S)-3-(3-tert-butyl-1,2,4-oxadiazol-5-yl)-1-({(2S)-1-[(4-methylbenzyl)amino]-1-oxo-4-phenylbutan-2-yl}amino)-1-oxopropan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide, ... 著者 Sintchak, M.D. 登録日 2011-06-09 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome. Bioorg.Med.Chem.Lett., 20, 2010
3V2J	Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Aggarwal, M, McKenna, A. 登録日 2011-12-12 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II To be Published
3V2P	COMPcc in complex with fatty acids 分子名称: Cartilage Oligomerization matrix protein (coiled-coil domain), STEARIC ACID 著者 Stetefeld, J. 登録日 2011-12-12 公開日 2013-01-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.873 Å) 主引用文献 The pentameric channel of COMPcc in complex with different fatty acids. Plos One, 7, 2012
3V3F	Kinetic and structural studies of thermostabilized mutants of HCA II. 分子名称: CHLORIDE ION, Carbonic anhydrase 2, ZINC ION 著者 Boone, C.D, Fisher, S.Z, McKenna, R. 登録日 2011-12-13 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II. Protein Eng.Des.Sel., 25, 2012
3V1U	Crystal structure of a beta-ketoacyl reductase FabG4 from Mycobacterium tuberculosis H37Rv complexed with NAD+ and Hexanoyl-CoA at 2.5 Angstrom resolution 分子名称: (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, 3-oxoacyl-(Acyl-carrier-protein) reductase, HEXANOYL-COENZYME A, ... 著者 Dutta, D, Bhattacharyya, S, Das, A.K. 登録日 2011-12-10 公開日 2012-11-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of hexanoyl-CoA bound to beta-ketoacyl reductase FabG4 of Mycobacterium tuberculosis Biochem.J., 450, 2013
3V3G	Kinetic and structural studies of thermostabilized mutants of HCA II. 分子名称: CHLORIDE ION, Carbonic anhydrase 2, ZINC ION 著者 Boone, C.D, Fisher, S.Z, McKenna, R. 登録日 2011-12-13 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5581 Å) 主引用文献 Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II. Protein Eng.Des.Sel., 25, 2012
3V4M	Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution 分子名称: CHLORIDE ION, SODIUM ION, Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-12-15 公開日 2012-06-13 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution To be published
3V43	Crystal structure of MOZ 分子名称: ACETATE ION, Histone H3.1, Histone acetyltransferase KAT6A, ... 著者 Qiu, Y, Li, F. 登録日 2011-12-14 公開日 2012-06-27 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription Genes Dev., 26, 2012
3V62	Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164 分子名称: ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
3UK0	RPD_1889 protein, an extracellular ligand-binding receptor from Rhodopseudomonas palustris. 分子名称: 1,2-ETHANEDIOL, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, Extracellular ligand-binding receptor, ... 著者 Osipiuk, J, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2011-11-08 公開日 2011-11-23 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins, 81, 2013
3V72	Crystal Structure of Rat DNA polymerase beta Mutator E295K: Enzyme-dsDNA 分子名称: CHLORIDE ION, DNA 5'-D(P*AP*AP*AP*CP*TP*CP*AP*CP*AP*T)-3', DNA 5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3', ... 著者 Gridley, C.L, Jaeger, J. 登録日 2011-12-20 公開日 2012-07-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Unfavorable Electrostatic and Steric Interactions in DNA Polymerase beta E295K Mutant Interfere with the Enzyme s Pathway J.Am.Chem.Soc., 134, 2012

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