PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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5SJE	Crystal Structure of human phosphodiesterase 10 in complex with 3-[2-(2,2-difluoro-1,3-benzodioxol-4-yl)pyrazol-3-yl]-1-(3-methylsulfonylphenyl)pyridazin-4-one 分子名称: 3-[1-(2,2-difluoro-2H-1,3-benzodioxol-4-yl)-1H-pyrazol-5-yl]-1-[3-(methanesulfonyl)phenyl]pyridazin-4(1H)-one, CHLORIDE ION, GLYCEROL, ... 著者 Joseph, C, Benz, J, Flohr, A, Rodriguez-Sarmiento, R.M, Rudolph, M.G. 登録日 2022-02-01 公開日 2022-10-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of a human phosphodiesterase 10 complex To be published
1JOU	Crystal Structure of Native S195A Thrombin with an Unoccupied Active Site 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, GLYCEROL, ... 著者 Huntington, J.A, Esmon, C.T. 登録日 2001-07-31 公開日 2001-08-10 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The molecular basis of thrombin allostery revealed by a 1.8A structure of the slow form Structure, 11, 2003
8EPH	Crystal structure of human coagulation factor IXa (S195A), apo-form, DES-GLA 分子名称: CALCIUM ION, Coagulation factor IXa heavy chain, Coagulation factor IXa light chain, ... 著者 Kolyadko, V.N, Krishnaswamy, S. 登録日 2022-10-05 公開日 2024-07-03 最終更新日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc.Natl.Acad.Sci.USA, 121, 2024
8EPC	Crystal structure of human coagulation factor IXa (S195A), apo-form 分子名称: CALCIUM ION, Coagulation factor IXa heavy chain, Coagulation factor IXa light chain 著者 Kolyadko, V.N, Krishnaswamy, S. 登録日 2022-10-05 公開日 2024-07-03 最終更新日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc.Natl.Acad.Sci.USA, 121, 2024
8EPK	Complex of anticoagulant RNA aptamer and human coagulation factor IXa (S195A) 分子名称: CALCIUM ION, Coagulation factor IXa heavy chain, Coagulation factor IXa light chain, ... 著者 Kolyadko, V.N, Krishnaswamy, S. 登録日 2022-10-05 公開日 2024-07-03 最終更新日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc.Natl.Acad.Sci.USA, 121, 2024
6AA7	Fluorescent protein from Acropora digitifera 分子名称: Fluorescent protein 著者 Kim, S.E, Hwang, K.Y, Nam, K.H. 登録日 2018-07-17 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Spectral and structural analysis of a red fluorescent protein from Acropora digitifera. Protein Sci., 28, 2019
6YBJ	Structure of MBP-Mcl-1 in complex with compound 3e 分子名称: (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(5-fluoranylfuran-2-yl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-[(2-methylpyrazol-3-yl)methoxy]phenyl]propanoic acid, CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, ... 著者 Dokurno, P, Surgenor, A.E, Murray, J.B. 登録日 2020-03-17 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor. J.Med.Chem., 63, 2020
2BUW	Crystal Structure of Protocatechuate 3,4-Dioxygenase from Acinetobacter Sp. ADP1 Mutant R457S in Complex with 4-Hydroxybenzoate 分子名称: FE (III) ION, P-HYDROXYBENZOIC ACID, PROTOCATECHUATE 3,4-DIOXYGENASE ALPHA CHAIN, ... 著者 Vetting, M.W, Valley, M.P, D'Argenio, D.A, Ornston, L.N, Lipscomb, J.D, Ohlendorf, D.H. 登録日 2005-06-20 公開日 2006-10-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic Studies of Intradiol Dioxygenases. Phd Thesis, 2001
8FWA	Phycocyanin structure from a modular droplet injector for serial femtosecond crystallography 分子名称: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHYCOCYANOBILIN, ... 著者 Botha, S, Doppler, D.L, Sonker, M, Egatz-Gomez, A, Grieco, A, Zaare, S, Jernigan, R, Meza-Aguilar, J.D, Rabbani, M.T, Manna, A, Alvarez, R, Karpos, K, Cruz Villarreal, J, Nelson, G, Ketawala, G.K, Pey, A.L, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Nazari, R, Sierra, R, Hunter, M.S, Batyuk, A, Kupitz, C.J, Sublett, R.E, Lisova, S, Mariani, V, Boutet, S, Fromme, R, Grant, T.D, Fromme, P, Kirian, R.A, Martin-Garcia, J.M, Ros, A. 登録日 2023-01-20 公開日 2023-06-28 最終更新日 2023-07-12 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme. Lab Chip, 23, 2023
8F8O	Crystal Structure of the Succinyl-diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii in complex with Succinic and L-Lactic Acids 分子名称: (2S)-2-HYDROXYPROPANOIC ACID, CITRIC ACID, SUCCINIC ACID, ... 著者 Minasov, G, Shuvalova, L, Brunzelle, J.S, Dubrovska, I, Pshenychnyi, S, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2022-11-22 公開日 2022-11-30 最終更新日 2023-02-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of the Succinyl-diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii in complex with Succinic and L-Lactic Acids To Be Published
4X6O	FACTOR XIA IN COMPLEX WITH THE INHIBITOR methyl (4-{4-chloro-2-[(1S)-1-({3-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]propanoyl}amino)-2-phenylethyl]-1H-imidazol-5-yl}phenyl)carbamate 分子名称: 1,2-ETHANEDIOL, Coagulation factor XI, light chain, ... 著者 Wei, A. 登録日 2014-12-08 公開日 2015-02-18 最終更新日 2015-04-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties. Bioorg.Med.Chem.Lett., 25, 2015
6YO2	Meta-Carborane propyl-sulfonamide in complex with CA IX mimic 分子名称: Carbonic anhydrase 2, Meta-Carborane propyl-sulfonamide, ZINC ION 著者 Kugler, M, Brynda, J, Pospisilova, K, Rezacova, P. 登録日 2020-04-14 公開日 2020-08-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Dicarba-closo-dodecaboranes: The Influence of Stereochemistry on Inhibitory Activity against the Cancer-Associated Carbonic Anhydrase IX Isoenzyme. Chemistry, 26, 2020
5B80	Crystal Structure of Hyperthermophilic Thermotoga maritima L-Ketose-3-Epimerase with Cu2+ 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, COPPER (II) ION, Uncharacterized protein TM_0416 著者 Cao, T.P, Shin, S.M, Lee, D.W, Lee, S.H. 登録日 2016-06-10 公開日 2017-03-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 TM0416, a Hyperthermophilic Promiscuous Nonphosphorylated Sugar Isomerase, Catalyzes Various C5and C6Epimerization Reactions Appl. Environ. Microbiol., 83, 2017
6Y10	X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126H 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, R-specific alcohol dehydrogenase 著者 Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. 登録日 2020-02-10 公開日 2020-02-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
5EQZ	Crystal structure of a Rev protein from Borrelia burgdorferi at 1.80 A resolution 分子名称: Rev protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2015-11-13 公開日 2015-12-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a Rev protein from Borrelia burgdorferi at 1.80 A resolution to be published
8FBH	Crystal structure of NSD1 Mutant-T1927A 分子名称: Histone-lysine N-methyltransferase, H3 lysine-36 specific, S-ADENOSYLMETHIONINE, ... 著者 Providokhina, K, Dong, A, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2022-11-29 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Crystal structure of NSD1 To Be Published
1JWP	Structure of M182T mutant of TEM-1 beta-lactamase 分子名称: BETA-LACTAMASE TEM, PHOSPHATE ION 著者 Wang, X, Minasov, G, Shoichet, B.K. 登録日 2001-09-04 公開日 2002-06-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs. J.Mol.Biol., 320, 2002
2BUQ	Crystal Structure Of Wild-Type Protocatechuate 3,4-Dioxygenase from Acinetobacter Sp. ADP1 in Complex with Catechol 分子名称: CATECHOL, FE (III) ION, PROTOCATECHUATE 3,4-DIOXYGENASE ALPHA CHAIN, ... 著者 Vetting, M.W, Valley, M.P, D'Argenio, D.A, Ornston, L.N, Lipscomb, J.D, Ohlendorf, D.H. 登録日 2005-06-17 公開日 2006-09-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biophysical Analyses of Designed and Selected Mutants of Protocatechuate 3,4-Dioxygenase Annu.Rev.Microbiol., 58, 2004
6YF5	Lamin A 17-70 coil1A dimer stabilized by C-terminal capping 分子名称: Prelamin-A/C,Microtubule-associated protein RP/EB family member 1 著者 Lilina, A.V, Stalmans, G, Strelkov, S.V. 登録日 2020-03-26 公開日 2020-09-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions. Cells, 9, 2020
2BUU	Crystal Structure Of Protocatechuate 3,4-Dioxygenase from Acinetobacter Sp. ADP1 Mutant R457S in complex with 4-Nitrocatechol 分子名称: 4-NITROCATECHOL, FE (III) ION, PROTOCATECHUATE 3,4-DIOXYGENASE ALPHA CHAIN, ... 著者 Vetting, M.W, Valley, M.P, D'Argenio, D.A, Ornston, L.N, Lipscomb, J.D, Ohlendorf, D.H. 登録日 2005-06-17 公開日 2006-10-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic Studies of Intradiol Dioxygenases. Phd Thesis, 2001
1K24	Crystal Structure of the OpcA Outer Membrane Adhesin/Invasin from Neisseria meningitidis 分子名称: PENTAETHYLENE GLYCOL, ZINC ION, outer membrane protein 著者 Prince, S.M, Achtman, M, Derrick, J.P. 登録日 2001-09-26 公開日 2002-03-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal structure of the OpcA integral membrane adhesin from Neisseria meningitidis. Proc.Natl.Acad.Sci.USA, 99, 2002
2BUT	Crystal Structure Of Protocatechuate 3,4-Dioxygenase from Acinetobacter Sp. ADP1 Mutant R457S - APO 分子名称: FE (III) ION, HYDROXIDE ION, PROTOCATECHUATE 3,4-DIOXYGENASE ALPHA CHAIN, ... 著者 Vetting, M.W, Valley, M.P, D'Argenio, D.A, Ornston, L.N, Lipscomb, J.D, Ohlendorf, D.H. 登録日 2005-06-17 公開日 2006-09-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Biophysical Analyses of Designed and Selected Mutants of Protocatechuate 3,4-Dioxygenase Annu.Rev.Microbiol., 58, 2004
4WX1	Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A determined from a crystal soaked with UDP-Galactopyranose 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... 著者 Qureshi, I.A, Chaudhary, R. 登録日 2014-11-13 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
2BUY	Crystal Structure of Protocatechuate 3,4-Dioxygenase from Acinetobacter Sp. ADP1 Mutant R133H in Complex with Catechol 分子名称: CATECHOL, FE (III) ION, PROTOCATECHUATE 3,4-DIOXYGENASE ALPHA CHAIN, ... 著者 Vetting, M.W, Valley, M.P, D'Argenio, D.A, Ornston, L.N, Lipscomb, J.D, Ohlendorf, D.H. 登録日 2005-06-20 公開日 2006-10-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic Studies of Intradiol Dioxygenases. Phd Thesis, 2001
2BV0	Crystal Structure of Protocatechuate 3,4-Dioxygenase from Acinetobacter Sp. ADP1 Mutant R133H in Complex with Protocatechuate. 分子名称: 3,4-DIHYDROXYBENZOIC ACID, FE (III) ION, PROTOCATECHUATE 3,4-DIOXYGENASE ALPHA CHAIN, ... 著者 Vetting, M.W, Valley, M.P, D'Argenio, D.A, Ornston, L.N, Lipscomb, J.D, Ohlendorf, D.H. 登録日 2005-06-20 公開日 2006-10-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic Studies of Intradiol Dioxygenases. Phd Thesis, 2001

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