PDB: 45176 件ウェブページステータス検索Chemie searchBIRD

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444D	5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX 分子名称: 2'-(3-IODO-4-METHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') 著者 Clark, G.R, Squire, C.J, Martin, R.F, White, J. 登録日 1999-01-14 公開日 2000-02-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design. Nucleic Acids Res., 28, 2000
455D	A6/A18 INTER-STRAND DITHIOBIS(PROPANE)-CROSSLINKED DODECAMER (CGCGAATTCGCG)2 分子名称: DITHIOBIS-(PROPANE), DNA (5'-D(*CP*GP*CP*GP*AP*(SSP)AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION 著者 Chiu, T.K, Kaczor-Grzeskowiak, M, Dickerson, R.E. 登録日 1999-03-04 公開日 1999-10-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Absence of minor groove monovalent cations in the crosslinked dodecamer C-G-C-G-A-A-T-T-C-G-C-G. J.Mol.Biol., 292, 1999
413D	A'-FORM RNA DOUBLE HELIX IN THE SINGLE CRYSTAL STRUCTURE OF R(UGAGCUUCGGCUC) 分子名称: RNA (5'-R(*UP*GP*AP*GP*CP*UP*UP*CP*GP*GP*CP*UP*C)-3') 著者 Tanaka, Y, Fujii, S, Hiroaki, H, Sakata, T, Tanaka, T, Uesugi, S, Tomita, K.-I, Kyogoku, Y. 登録日 1998-07-10 公開日 1998-07-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A'-form RNA double helix in the single crystal structure of r(UGAGCUUCGGCUC). Nucleic Acids Res., 27, 1999
422D	5'-R(*GP*AP*UP*CP*AP*CP*UP*UP*CP*GP*GP*U)-3' 分子名称: 5'-R(*GP*AP*UP*CP*AP*CP*UP*UP*CP*GP*GP*U)-3' 著者 Eswaramoorthy, S, Rao, S.T, Sundaralingam, M. 登録日 1998-09-10 公開日 2003-06-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the dodecamer r(GAUCACUUCGGU) with four 5'-overhang nucleotides. Acta Crystallogr.,Sect.D, 60, 2004
430D	STRUCTURE OF SARCIN/RICIN LOOP FROM RAT 28S RRNA 分子名称: MAGNESIUM ION, SARCIN/RICIN LOOP FROM RAT 28S R-RNA 著者 Correll, C.C, Munishkin, A, Chan, Y.L, Ren, Z, Wool, I.G, Steitz, T.A. 登録日 1998-10-04 公開日 1998-10-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the ribosomal RNA domain essential for binding elongation factors. Proc.Natl.Acad.Sci.USA, 95, 1998
456C	CRYSTAL STRUCTURE OF COLLAGENASE-3 (MMP-13) COMPLEXED TO A DIPHENYL-ETHER SULPHONE BASED HYDROXAMIC ACID 分子名称: 2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE, CALCIUM ION, MMP-13, ... 著者 Lovejoy, B, Welch, A, Carr, S, Luong, C, Broka, C, Hendricks, R.T, Campbell, J, Walker, K, Martin, R, Van Wart, H, Browner, M.F. 登録日 1998-08-06 公開日 1999-08-06 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors. Nat.Struct.Biol., 6, 1999
477D	CALCIUM FORM OF THE B-DNA DODECAMER GGCGAATTCGCG 分子名称: 5'-D(*GP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', CALCIUM ION 著者 Minasov, G, Tereshko, V, Egli, M. 登録日 1999-06-25 公開日 1999-07-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Atomic-resolution crystal structures of B-DNA reveal specific influences of divalent metal ions on conformation and packing. J.Mol.Biol., 291, 1999
3PUD	Crystal structure of Dhydrodipicolinate synthase from Acinetobacter baumannii at 2.8A resolution 分子名称: Dihydrodipicolinate synthase, GLYCEROL, SULFATE ION 著者 Jithesh, O, Yamini, S, Kaur, N, Gautam, A, Tewari, R, Kushwaha, G.S, Kaur, P, Srinivasan, A, Sharma, S, Singh, T.P. 登録日 2010-12-04 公開日 2010-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of Dhydrodipicolinate synthase from Acinetobacter baumannii at 2.8A resolution To be Published
4AOI	Crystal structure of C-MET kinase domain in complex with 4-(3-((1H- pyrrolo(2,3-b)pyridin-3-yl)methyl)-(1,2,4)triazolo(4,3-b)(1,2,4) triazin-6-yl)benzonitrile 分子名称: 4-[3-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-6-yl]benzenecarbonitrile, HEPATOCYTE GROWTH FACTOR RECEPTOR 著者 McTigue, M, Grodsky, N, Ryan, K, Cui, J.J. 登録日 2012-03-27 公開日 2012-09-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (C-met) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-Ylmethyl)-1H-[1,2, 3]Triazolo[4,5-B]Pyrazin-6-Yl)-1H-Pyrazol-1-Yl)Ethanol (Pf-04217903) for the Treatment of Cancer. J.Med.Chem., 55, 2012
3PVI	D34G MUTANT OF PVUII ENDONUCLEASE COMPLEXED WITH COGNATE DNA SHOWS THAT ASP34 IS DIRECTLY INVOLVED IN DNA RECOGNITION AND INDIRECTLY INVOLVED IN CATALYSIS 分子名称: DNA (5'-D(*TP*GP*AP*CP*CP*AP*GP*CP*TP*GP*GP*TP*C)-3'), PROTEIN (PVUII ENDONUCLEASE) 著者 Horton, J.R, Cheng, X. 登録日 1998-10-09 公開日 1998-10-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Asp34 of PvuII endonuclease is directly involved in DNA minor groove recognition and indirectly involved in catalysis. J.Mol.Biol., 284, 1998
4AP7	Crystal structure of C-MET kinase domain in complex with 4-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl)phenol 分子名称: 4-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]phenol, HEPATOCYTE GROWTH FACTOR RECEPTOR 著者 McTigue, M, Wickersham, J. 登録日 2012-03-30 公開日 2012-09-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (C-met) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-Ylmethyl)-1H-[1,2, 3]Triazolo[4,5-B]Pyrazin-6-Yl)-1H-Pyrazol-1-Yl)Ethanol (Pf-04217903) for the Treatment of Cancer. J.Med.Chem., 55, 2012
3PHM	REDUCED (CU+) PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE (PHM) 分子名称: AZIDE ION, COPPER (II) ION, GLYCEROL, ... 著者 Prigge, S.T, Amzel, L.M. 登録日 1999-05-25 公開日 1999-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Substrate-mediated electron transfer in peptidylglycine alpha-hydroxylating monooxygenase. Nat.Struct.Biol., 6, 1999
3MUS	2A Resolution Structure of Rat Type B Cytochrome b5 分子名称: Cytochrome b5 type B, PROTOPORPHYRIN IX CONTAINING FE 著者 Terzyan, S, Zhang, X, Benson, D.R. 登録日 2010-05-03 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Accommodating a Non-Conservative Internal Mutation by Water-Mediated Hydrogen-Bonding Between beta-Sheet Strands: A Comparison of Human and Rat Type B (Mitochondrial) Cytochrome b5 Biochemistry, 50, 2011
3R73	CDK2 in complex with inhibitor KVR-1-164 分子名称: 1,2-ETHANEDIOL, 4-[(3-aminopropyl)amino]-5-nitro-2-[(pyridin-3-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-22 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
4AXN	Hallmarks of processive and non-processive glycoside hydrolases revealed from computational and crystallographic studies of the Serratia marcescens chitinases 分子名称: ACETATE ION, CALCIUM ION, CHITINASE C1 著者 Payne, C.M, Baban, J, Synstad, B, Backe, P.H, Arvai, A.S, Dalhus, B, Bjoras, M, Eijsink, V.G.H, Sorlie, M, Beckham, G.T, Vaaje-Kolstad, G. 登録日 2012-06-13 公開日 2012-09-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Hallmarks of Processivity in Glycoside Hydrolases from Crystallographic and Computational Studies of the Serratia Marcescens Chitinases. J.Biol.Chem., 287, 2012
3R8V	CDK2 in complex with inhibitor RC-1-135 分子名称: Cyclin-dependent kinase 2, [4-amino-2-(prop-2-en-1-ylamino)-1,3-thiazol-5-yl](3-nitrophenyl)methanone 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-24 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
7A4J	Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-4 分子名称: Antitermination protein N,6,7-dimethyl-8-ribityllumazine synthase,6,7-dimethyl-8-ribityllumazine synthase 著者 Tetter, S, Hilvert, D. 登録日 2020-08-19 公開日 2021-06-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein. Science, 372, 2021
3RJC	CDK2 in complex with inhibitor L4-12 分子名称: Cyclin-dependent kinase 2, {4-amino-2-[(3-fluorophenyl)amino]-1,3-thiazol-5-yl}(phenyl)methanone 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-04-15 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
2XMA	DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE RIGHT END DNA COMPLEX 分子名称: DRA2 TRANSPOSASE RIGHT END RECOGNITION SITE, MAGNESIUM ION, TRANSPOSASE 著者 Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F. 登録日 2010-07-26 公開日 2010-10-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans. Embo J., 29, 2010
4ASE	CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH TIVOZANIB (AV-951) 分子名称: TIVOZANIB, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 著者 McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A. 登録日 2012-04-30 公開日 2012-09-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
3R28	CDK2 in complex with inhibitor KVR-1-140 分子名称: 1,2-ETHANEDIOL, 4-chloro-5-nitro-2-[(3,4,5-trifluorobenzyl)amino]benzamide, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-14 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3R7I	CDK2 in complex with inhibitor KVR-1-74 分子名称: 1,2-ETHANEDIOL, 4-{[(2-carbamoyl-4-nitrophenyl)amino]methyl}benzoic acid, Cyclin-dependent kinase 2 著者 Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. 登録日 2011-03-22 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
3N7K	Crystal structure of botulinum neurotoxin serotype C1 binding domain 分子名称: Botulinum neurotoxin type C1 著者 Fu, Z, Kroken, A, Karalewitz, A, Baldwin, M.R, Barbieri, J.T, Kim, J.-J.P. 登録日 2010-05-27 公開日 2010-09-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA . Biochemistry, 49, 2010
4BGN	cryo-EM structure of the NavCt voltage-gated sodium channel 分子名称: VOLTAGE-GATED SODIUM CHANNEL 著者 Tsai, C.J, Tani, K, Irie, K, Hiroaki, Y, Shimomura, T, Mcmillan, D.G, Cook, G.M, Schertler, G, Fujiyoshi, Y, Li, X.D. 登録日 2013-03-28 公開日 2013-07-10 最終更新日 2023-12-20 実験手法 ELECTRON CRYSTALLOGRAPHY (9 Å) 主引用文献 Two Alternative Conformations of a Voltage-Gated Sodium Channel. J.Mol.Biol., 425, 2013
3PUE	Crystal structure of the complex of Dhydrodipicolinate synthase from Acinetobacter baumannii with lysine at 2.6A resolution 分子名称: Dihydrodipicolinate synthase, GLYCEROL, LYSINE, ... 著者 Jithesh, O, Yamini, S, Kaur, N, Gautam, A, Tewari, R, Kushwaha, G.S, Kaur, P, Srinivasan, A, Sharma, S, Singh, T.P. 登録日 2010-12-04 公開日 2010-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the complex of Dhydrodipicolinate synthase from Acinetobacter baumannii with lysine at 2.6A resolution To be Published

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