PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3S8P	Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine 分子名称: Histone-lysine N-methyltransferase SUV420H1, S-ADENOSYLMETHIONINE, ZINC ION 著者 Lam, R, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2011-05-30 公開日 2011-07-06 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. Febs Lett., 587, 2013
3S97	PTPRZ CNTN1 complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Contactin-1, Receptor-type tyrosine-protein phosphatase zeta 著者 Bouyain, S. 登録日 2011-05-31 公開日 2011-09-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2971 Å) 主引用文献 A complex between contactin-1 and the protein tyrosine phosphatase PTPRZ controls the development of oligodendrocyte precursor cells. Proc.Natl.Acad.Sci.USA, 108, 2011
3SK6	Crystal structure of Staphylococcal nuclease variant Delta+NVIAGLA V23K/L36E at cryogenic temperature 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Robinson, A.C, Schlessman, J.L, Garcia-Moreno E, B. 登録日 2011-06-22 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Staphylococcal nuclease variant Delta+NVIAGLA V23K/L36E at cryogenic temperature To be Published
3SA4	Crystal structure of wild-type HIV-1 protease in complex with AF72 分子名称: ACETATE ION, N-{(2S,3R)-4-[(1,3-benzothiazol-6-ylsulfonyl)(cyclohexylmethyl)amino]-3-hydroxy-1-phenylbutan-2-yl}-3-hydroxybenzamide, PHOSPHATE ION, ... 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SAC	Crystal structure of wild-type HIV-1 protease in complex with AF80 分子名称: 3-hydroxy-N-{(2S,3R)-3-hydroxy-4-[(2-methylpropyl){[5-(1,2-oxazol-5-yl)thiophen-2-yl]sulfonyl}amino]-1-phenylbutan-2-yl}benzamide, PHOSPHATE ION, Protease 著者 Schiffer, C.A, Nalam, M.N.L. 登録日 2011-06-02 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protease Inhibitors that protrude out from substrate envelope are more susceptible to developing drug resistance To be Published
3SBI	Crystal structure of human carbonic anhydrase isozyme II with 4-[(2-pyrimidinylsulfanyl)acetyl]benzenesulfonamide 分子名称: 4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-05 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
3SL3	Crystal structure of the apo form of the catalytic domain of PDE4D2 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Feil, S.F. 登録日 2011-06-24 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg.Med.Chem.Lett., 21, 2011
3SBU	Crystal structure of a ntf2-like protein (BF2862) from Bacteroides fragilis NCTC 9343 at 2.15 A resolution 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Hypothetical ntf2-like protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-06-06 公開日 2011-07-13 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a Hypothetical ntf2-like protein (BF2862) from Bacteroides fragilis NCTC 9343 at 2.15 A resolution To be published
3SNV	Crystal structure of Symfoil-4T Permutation #1: de novo designed beta-trefoil architecture with symmetric primary structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, Symfoil-4T/Permutation #1 synthetic protein 著者 Blaber, M, Longo, L, Lee, J. 登録日 2011-06-29 公開日 2012-07-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Folding pathway redundancy in symmetric protein architecture To be Published
3SO5	Crystal structure of an Immunoglobulin I-set domain of Lrig3 protein (Lrig3) from MUS MUSCULUS at 1.70 A resolution 分子名称: CHLORIDE ION, Leucine-rich repeats and immunoglobulin-like domains protein 3, SULFATE ION 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2011-06-29 公開日 2011-07-27 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of an Immunoglobulin I-set domain of Lrig3 protein (Lrig3) from MUS MUSCULUS at 1.70 A resolution To be published
3S29	The crystal structure of sucrose synthase-1 from Arabidopsis thaliana and its functional implications. 分子名称: MALONIC ACID, POTASSIUM ION, SULFATE ION, ... 著者 Zheng, Y.I, Garavito, R.M. 登録日 2011-05-16 公開日 2011-08-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications. J.Biol.Chem., 286, 2011
3SH5	Calcium-bound Laminin G like domain 3 from human perlecan 分子名称: CALCIUM ION, LG3 peptide 著者 Van Le, B, Kim, K.K. 登録日 2011-06-16 公開日 2011-12-14 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of the LG3 Domain of Endorepellin, an Angiogenesis Inhibitor. J.Mol.Biol., 414, 2011
3S4C	Lactose phosphorylase in complex with sulfate 分子名称: 1,4-DIETHYLENE DIOXIDE, Lactose Phosphorylase, SULFATE ION 著者 Van Hoorebeke, A, Stout, J, Soetaert, W, Van Beeumen, J, Desmet, T, Savvides, S. 登録日 2011-05-19 公開日 2012-06-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Cellobiose phosphorylase: reconstructing the structural itinerary along the catalytic pathway To be Published
3S5T	Crystal structure of a member of duf3298 family (BF2082) from bacteroides fragilis nctc 9343 at 2.30 A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, DUF3298 family protein, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-05-23 公開日 2011-06-29 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a Member of DUF3298 family (BF2082) from Bacteroides fragilis NCTC 9343 at 2.30 A resolution To be published
3SHZ	Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors 分子名称: 5-chloro-6-ethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... 著者 Chen, T.T, Chen, T, Xu, Y.C. 登録日 2011-06-17 公開日 2011-08-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.449 Å) 主引用文献 Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors. J.Med.Chem., 54, 2011
3TKQ	Crystal structure of full-length human peroxiredoxin 4 with mixed conformation 分子名称: Peroxiredoxin-4 著者 Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. 登録日 2011-08-28 公開日 2011-10-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4 Biochem.J., 2011
3TJP	Crystal Structure of PI3K gamma with N6-(3,4-dimethoxyphenyl)-2-morpholino-[4,5'-bipyrimidine]-2',6-diamine 分子名称: N~6~-(3,4-dimethoxyphenyl)-2-(morpholin-4-yl)-4,5'-bipyrimidine-2',6-diamine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION 著者 Knapp, M.S, Elling, R.A, Ornelas, E. 登録日 2011-08-24 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Identification of 5-(2,4-dimorpholinopyrimidin-6-yl)-4-(trifluoromethyl)pyridin-2-amine (NVP-BKM120) as a Potent, Selective and Orally Bioavailable Class I PI3 Kinase Inhibitor for the Treatment of Cancer To be Published
3TP7	Crystal structure of Staphylococcal nuclease variant Delta+PHS V99E at cryogenic temperature 分子名称: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease 著者 Robinson, A.C, Schlessman, J.L, Garcia-Moreno E, B. 登録日 2011-09-07 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Staphylococcal nuclease variant Delta+PHS V99E at cryogenic temperature To be Published
3TP2	Crystal Structure of the Splicing Factor Cwc2 from yeast 分子名称: Pre-mRNA-splicing factor CWC2, SODIUM ION, ZINC ION 著者 Schmitzova, J. 登録日 2011-09-07 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Cwc2 reveals a novel architecture of a multipartite RNA-binding protein. Embo J., 31, 2012
3TPP	Crystal structure of BACE1 complexed with an inhibitor 分子名称: Beta-secretase 1, CHLORIDE ION, N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N'-[(1R)-1-PHENYLETHYL]ISOPHTHALAMIDE, ... 著者 Xu, Y.C, Li, M.J, Greenblatt, H, Chen, T.T, Silman, I, Sussman, J.L. 登録日 2011-09-08 公開日 2011-11-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations Acta Crystallogr.,Sect.D, 68, 2012
3TQN	Structure of the transcriptional regulator of the GntR family, from Coxiella burnetii. 分子名称: Transcriptional regulator, GntR family 著者 Rudolph, M, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-28 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
3TQZ	Structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) from Coxiella burnetii 分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, SULFATE ION 著者 Cheung, J, Franklin, M, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
3TQT	Structure of the D-alanine-D-alanine ligase from Coxiella burnetii 分子名称: D-alanine--D-alanine ligase 著者 Rudolph, M, Cheung, J, Franklin, M.C, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
3TR6	Structure of a O-methyltransferase from Coxiella burnetii 分子名称: NICKEL (II) ION, O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-28 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
3TRB	Structure of an addiction module antidote protein of a HigA (higA) family from Coxiella burnetii 分子名称: Virulence-associated protein I 著者 Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-28 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015

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