6P98
| OXA-48 carbapanemase, meropenem complex | 分子名称: | Beta-lactamase, CADMIUM ION, CALCIUM ION, ... | 著者 | Smith, C.A, Vakulenko, S.B. | 登録日 | 2019-06-10 | 公開日 | 2019-08-07 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 beta-Lactamase. Antimicrob.Agents Chemother., 63, 2019
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8DRL
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8DQ9
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8PG3
| Crystal structure of the metallo-beta-lactamase VIM1 with 2729 | 分子名称: | 7-[(1~{S})-1-[5-(2-azanylethyl)-2-oxidanylidene-1,3-oxazolidin-3-yl]ethyl]-3-[3-fluoranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION | 著者 | Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. | 登録日 | 2023-06-18 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Crystal structure of the metallo-beta-lactamase VIM1 with 2729 To Be Published
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8PTT
| Human NUDT5 in complex with MRK-952 | 分子名称: | 6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine, ADP-sugar pyrophosphatase, MAGNESIUM ION | 著者 | Diaz-Saez, L, Koekemoer, L, Feyerherm, C, Sloman, S, Fischer, C, Schneider, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Huber, K.V.M. | 登録日 | 2023-07-14 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Human NUDT5 in complex with MRK-952 To Be Published
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6N5I
| FtsY-NG high-resolution | 分子名称: | GLYCEROL, POTASSIUM ION, Signal recognition particle receptor FtsY | 著者 | Ataide, S.F, Faoro, C. | 登録日 | 2018-11-21 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | 主引用文献 | Structural insights into the G-loop dynamics of E. coli FtsY NG domain. J.Struct.Biol., 208, 2019
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6VS9
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8PGN
| Crystal structure of the metallo-beta-lactamase VIM1 with 3169 | 分子名称: | 7-[(1~{S})-1-[5-[(3-azanylazetidin-1-yl)methyl]-2-oxidanylidene-1,3-oxazolidin-3-yl]ethyl]-3-[3-fluoranyl-4-(methylsulfonylamino)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION | 著者 | Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. | 登録日 | 2023-06-18 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | Crystal structure of the metallo-beta-lactamase VIM1 with 3169 To Be Published
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6MYE
| Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) | 分子名称: | FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ... | 著者 | Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J. | 登録日 | 2018-11-01 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility. J.Cell Biol., 218, 2019
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8DRF
| Zn(II)-bound B2 dimer (H60/H100/H104) | 分子名称: | HEME C, Soluble cytochrome b562, ZINC ION | 著者 | Choi, T.S, Tezcan, F.A. | 登録日 | 2022-07-20 | 公開日 | 2022-10-12 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design of a Flexible, Zn-Selective Protein Scaffold that Displays Anti-Irving-Williams Behavior. J.Am.Chem.Soc., 144, 2022
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6N5X
| Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1) | 分子名称: | GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor | 著者 | Collins, B, Paul, B, Weeratunga, S. | 登録日 | 2018-11-22 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.051 Å) | 主引用文献 | Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins. Nat.Cell Biol., 21, 2019
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7XIU
| Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester | 分子名称: | MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ZINC ION, ... | 著者 | Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T. | 登録日 | 2022-04-14 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity. J.Chem.Inf.Model., 62, 2022
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7O39
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6N67
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8PJZ
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7NRF
| Crystal structure of E.coli BamA beta-barrel in complex with darobactin (crystal form 2) | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Darobactin, MAGNESIUM ION, ... | 著者 | Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S. | 登録日 | 2021-03-03 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase. Nature, 593, 2021
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6PAR
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7NRE
| Crystal structure of E.coli BamA beta-barrel in complex with darobactin (crystal form 1) | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Darobactin, MAGNESIUM ION, ... | 著者 | Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S. | 登録日 | 2021-03-03 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase. Nature, 593, 2021
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7XJ5
| Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester | 分子名称: | MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ZINC ION, ... | 著者 | Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T. | 登録日 | 2022-04-15 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity. J.Chem.Inf.Model., 62, 2022
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6N6V
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8PM7
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8PGA
| Crystal structure of the metallo-beta-lactamase VIM1 with 2818 | 分子名称: | 7-[(1~{S})-1-[5-(3-azanylpropyl)-2-oxidanylidene-1,3-oxazolidin-3-yl]ethyl]-3-[3-fluoranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION | 著者 | Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. | 登録日 | 2023-06-18 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Crystal structure of the metallo-beta-lactamase VIM1 with 2818 To Be Published
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6N0S
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8PGP
| Crystal structure of the metallo-beta-lactamase VIM1 with 3193 | 分子名称: | 7-[(1~{S})-1-[5-[(3-azanylazetidin-1-yl)methyl]-2-oxidanylidene-1,3-oxazolidin-3-yl]ethyl]-3-[3-cyano-4-(methylsulfonylamino)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION | 著者 | Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J. | 登録日 | 2023-06-18 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Crystal structure of the metallo-beta-lactamase VIM1 with 3193 To Be Published
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7XIS
| Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester | 分子名称: | (2-methoxy-4-methoxycarbonyl-phenyl) 5-nitrofuran-2-carboxylate, MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ... | 著者 | Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T. | 登録日 | 2022-04-14 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity. J.Chem.Inf.Model., 62, 2022
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