PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3UVP	Human p38 MAP Kinase in Complex with a Benzamide Substituted Benzosuberone 分子名称: Mitogen-activated protein kinase 14, N-{2-fluoro-5-[(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino]phenyl}benzamide, octyl beta-D-glucopyranoside 著者 Mayer-Wrangowski, S.C, Richters, A, Gruetter, C, Rauh, D. 登録日 2011-11-30 公開日 2012-11-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Targeting the Hinge Glycine Flip and the Activation Loop: Novel Approach to Potent p38 alpha Inhibitors. J.Med.Chem., 55, 2012
3UW1	Crystal structure of ribose-5-phosphate isomerase a from burkholderia thailandensis with ribose-5-phosphate 分子名称: RIBOSE-5-PHOSPHATE, Ribose-5-phosphate isomerase A 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-30 公開日 2011-12-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3UQU	Crystal structure of BACE1 with its inhibitor 分子名称: Beta-secretase 1, CHLORIDE ION, N-[(1R)-1-(4-fluorophenyl)ethyl]-N'-[(2S,3S)-3-hydroxy-1-phenyl-4-(1H-pyrazol-1-yl)butan-2-yl]-5-[methyl(methylsulfonyl)amino]benzene-1,3-dicarboxamide, ... 著者 Chen, T.T, Chen, W.Y, Xu, Y.C. 登録日 2011-11-21 公開日 2012-11-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Flexibility of the Flap in the Active Site of BACE1 as Revealed by Crystal Structures and MD simulations to be published
3V51	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor RM-1-176 分子名称: 3-{6-[(3-chlorobenzyl)oxy]naphthalen-2-yl}-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-12-15 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
3V5J	Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 090 分子名称: 3-[4-(2-morpholin-4-ylethoxy)-2-(1~{H}-thieno[3,2-c]pyrazol-3-yl)-1~{H}-indol-6-yl]pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK 著者 McLean, L.R, Zhang, Y. 登録日 2011-12-16 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase. Bioorg.Med.Chem.Lett., 22, 2012
3V5P	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1288 分子名称: 3-(4-methoxy-3-methylphenyl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-12-16 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
3UW2	X-ray Crystal Structure of Phosphoglucomutase/phosphomannomutase family protein (BTH_I1489)from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-30 公開日 2012-02-01 最終更新日 2013-10-23 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3V60	Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 分子名称: Proliferating cell nuclear antigen, SULFATE ION, Ubiquitin-like protein SMT3 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
3UWS	Crystal structure of a clostripain (PARMER_00083) from Parabacteroides merdae ATCC 43184 at 1.70 A resolution 分子名称: 1,2-ETHANEDIOL, hypothetical protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-12-02 公開日 2012-06-13 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome. J.Biol.Chem., 291, 2016
3SX8	Crystal structure of ABBA+UDP+Gal with MPD as the cryoprotectant 分子名称: DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... 著者 Johal, A.R, Evans, S.V. 登録日 2011-07-14 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
3SXE	Crystal structure of AAAA+UDP+Gal with Glycerol as the cryoprotectant 分子名称: Histo-blood group ABO system transferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... 著者 Johal, A.R, Evans, S.V. 登録日 2011-07-14 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases. Acta Crystallogr.,Sect.D, 68, 2012
3SS6	Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase 分子名称: Acetyl-CoA acetyltransferase, POTASSIUM ION, SULFATE ION 著者 Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-07-07 公開日 2011-07-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase TO BE PUBLISHED
3SYP	Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) R201A mutant 分子名称: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION 著者 Whorton, M.R, MacKinnon, R. 登録日 2011-07-18 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium. Cell(Cambridge,Mass.), 147, 2011
3STC	Crystal structure of loop 7 truncated mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION 著者 Allison, T.M, Jameson, G.B, Parker, E.J. 登録日 2011-07-09 公開日 2011-11-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 An Extended (beta)7(alpha)7 Substrate-Binding Loop Is Essential for Efficient Catalysis by 3-Deoxy-D-manno-Octulosonate 8-Phosphate Synthase Biochemistry, 50, 2011
3STW	Crystal Structure of tomato Methylketone Synthase I complexed with 2-tridecanone 分子名称: Methylketone synthase 1, tridec-12-en-2-one 著者 Auldridge, M.E, Austin, M.B, Noel, J.P. 登録日 2011-07-11 公開日 2012-05-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Emergent Decarboxylase Activity and Attenuation of alpha/beta-Hydrolase Activity during the Evolution of Methylketone Biosynthesis in Tomato. Plant Cell, 24, 2012
3T00	Crystal Structure of Phosphonoacetate hydrolase from Sinorhizobium meliloti 1021 in complex with vanadate 分子名称: NICKEL (II) ION, VANADATE ION, ZINC ION, ... 著者 Agarwal, V, Nair, S.K. 登録日 2011-07-19 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and mechanistic insights into C-p bond hydrolysis by phosphonoacetate hydrolase. Chem.Biol., 18, 2011
3SY3	GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis 分子名称: GBAA_1210 protein, PHOSPHATE ION 著者 Osipiuk, J, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-07-15 公開日 2011-07-27 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 GBAA_1210 protein, a putative adenylate cyclase, from Bacillus anthracis. To be Published
3SYO	Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with sodium 分子名称: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION 著者 Whorton, M.R, MacKinnon, R. 登録日 2011-07-18 公開日 2011-10-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.54 Å) 主引用文献 Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium. Cell(Cambridge,Mass.), 147, 2011
3T6C	Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, D-gluconic acid, ... 著者 Vetting, M.W, Toro, R, Bhosle, R, Wasserman, S.R, Morisco, L.L, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2011-07-28 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.598 Å) 主引用文献 Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg to be published
3T8U	Crystal structure of ketosteroid isomerase Y14AY55FD99A from Pseudomonas testosteroni 分子名称: SULFATE ION, Steroid Delta-isomerase 著者 Gonzalez, A, Tsai, Y, Schwans, J, Sunden, F, Herschlag, D. 登録日 2011-08-01 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Evaluating the catalytic contribution from the oxyanion hole in ketosteroid isomerase. J.Am.Chem.Soc., 133, 2011
3T27	Orthorhombic trypsin (bovine) in the presence of betaine 分子名称: BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... 著者 Venkat, M, Saxby, C, Cahn, J, Juers, D. 登録日 2011-07-22 公開日 2011-12-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
3TAW	Crystal structure of a putative glycoside hydrolase (BDI_3141) from Parabacteroides distasonis ATCC 8503 at 1.70 A resolution 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Hypothetical glycoside hydrolase, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-08-04 公開日 2011-08-24 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of a Hypothetical glycoside hydrolase (BDI_3141) from Parabacteroides distasonis ATCC 8503 at 1.70 A resolution To be published
3T55	Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with Phenoxymethyl Benzoic Acid (PMBA) 分子名称: 3-(phenoxymethyl)benzoic acid, Indole-3-glycerol phosphate synthase, MALONATE ION, ... 著者 Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2011-07-26 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published
3TBJ	The 1.7A crystal structure of Actibind a T2 ribonucleases as antitumorigenic agents 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Almog, O, Gonzalez, A. 登録日 2011-08-07 公開日 2012-08-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The 1.8 A crystal structure of ACTIBIND suggests a mode of action for T2 ribonucleases as antitumorigenic agents. J.Med.Chem., 55, 2012
3SOX	Structure of UHRF1 PHD finger in the free form 分子名称: E3 ubiquitin-protein ligase UHRF1, ZINC ION 著者 Rajakumara, E, Patel, D.J. 登録日 2011-06-30 公開日 2011-08-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6501 Å) 主引用文献 PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression. Mol.Cell, 43, 2011

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