8IJW
| Cryo-EM structure of the gastric proton pump with bound DQ-06 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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8IJX
| Cryo-EM structure of the gastric proton pump with bound DQ-18 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[(5-chloranyl-2-phenylmethoxy-phenyl)methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.08 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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8IJL
| Cyo-EM structure of wildtype non-gastric proton pump in the presence of Na+, AlF and ADP | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | 著者 | Abe, K. | 登録日 | 2023-02-27 | 公開日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding. Biochim Biophys Acta Mol Cell Res, 1870, 2023
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8IWS
| hSPCA1 in the CaE2P state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-31 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWP
| hSPCA1 in the CaE1 state | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1 | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-30 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWT
| hSPCA1 in the early E2P state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-31 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWR
| hSPCA1 in the CaE1-ATP state | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, ... | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-31 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWU
| hSPCA1 in the E2~P state | 分子名称: | Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-31 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8IWW
| hSPCA1 in the CaE1P-ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | 登録日 | 2023-03-31 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
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8JFZ
| Cryo-EM structure of Na+,K+-ATPase in the E1.Mg2+ state. | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | 登録日 | 2023-05-19 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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8JBM
| Crystal structure of Na+,K+-ATPase in the E1.Mn2+ state | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | 登録日 | 2023-05-09 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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8JBL
| Crystal structure of Na+,K+-ATPase in the E1.Mg2+ state | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | 登録日 | 2023-05-09 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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8JBK
| Crystal structure of Na+,K+-ATPase in the E1.3Na+ state | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kanai, R, Vilsen, B, Cornelius, F, Toyoshima, C. | 登録日 | 2023-05-09 | 公開日 | 2023-08-09 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structures of Na + ,K + -ATPase reveal the mechanism that converts the K + -bound form to Na + -bound form and opens and closes the cytoplasmic gate. Febs Lett., 597, 2023
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8JMN
| Cryo-EM structure of the gastric proton pump with bound DQ-21 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[[2-[(4-chlorophenyl)methoxy]phenyl]methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-06-05 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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8OWA
| SR Ca(2+)-ATPase in the E2 state complexed with the photoswitch-thapsigargin derivative AzTG-4 | 分子名称: | ACETYL GROUP, SODIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, ... | 著者 | Hjorth-Jensen, S.J, Konrad, D.B, Quistgaard, E.M.H, Hansen, L.C, Novak, A, Chu, H, Jurasek, M, Zimmermann, T, Andersen, J.L, Baran, P.S, Nissen, P, Trauner, D. | 登録日 | 2023-04-27 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Photoswitchable inhibitors of the sarco(endo)plasmic calcium pump To Be Published
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8OWL
| SR Ca(2+)-ATPase in the E2 state complexed with the photoswitch-thapsigargin derivative AzTG-6 | 分子名称: | ACETYL GROUP, SODIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, ... | 著者 | Hjorth-Jensen, S.J, Konrad, D.B, Quistgaard, E.M.H, Hansen, L.C, Novak, A, Chu, H, Jurasek, M, Zimmermann, T, Andersen, J.L, Baran, P.S, Nissen, P, Trauner, D. | 登録日 | 2023-04-28 | 公開日 | 2023-06-21 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Photoswitchable inhibitors of the sarco(endo)plasmic calcium pump To Be Published
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8K1L
| Cryo-EM structure of Na+,K+-ATPase alpha2 from Artemia salina in cation-free E2P form | 分子名称: | Na+,K+-ATPase alpha2KK, Na+,K+-ATPase beta2, TETRAFLUOROALUMINATE ION | 著者 | Abe, K, Artigas, P. | 登録日 | 2023-07-11 | 公開日 | 2023-11-29 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | A Na pump with reduced stoichiometry is up-regulated by brine shrimp in extreme salinities. Proc.Natl.Acad.Sci.USA, 120, 2023
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8IJM
| Cyo-EM structure of K794A non-gastric proton pump in Na+ bound E1AMPPCP state | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Abe, K. | 登録日 | 2023-02-27 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | An unusual conformation from Na + -sensitive non-gastric proton pump mutants reveals molecular mechanisms of cooperative Na + -binding. Biochim Biophys Acta Mol Cell Res, 1870, 2023
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2YFY
| SERCA in the HnE2 State Complexed With Debutanoyl Thapsigargin | 分子名称: | DEBUTANOYL THAPSIGARGIN, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Sonntag, Y, Musgaard, M, Olesen, C, Schiott, B, Moller, J.V, Nissen, P, Thogersen, L. | 登録日 | 2011-04-11 | 公開日 | 2011-06-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Mutual Adaptation of a Membrane Protein and its Lipid Bilayer During Conformational Changes. Nat.Commun., 2, 2011
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2ZBG
| Calcium pump crystal structure with bound AlF4 and TG in the absence of calcium | 分子名称: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | 著者 | Toyoshima, C, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-12-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ZBD
| Crystal Structure of the SR Calcium Pump with Bound Aluminium Fluoride, ADP and Calcium | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Toyoshima, C, Nomura, H, Tsuda, T, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-11-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues Nature, 432, 2004
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2ZBE
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2ZXE
| Crystal structure of the sodium - potassium pump in the E2.2K+.Pi state | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Shinoda, T, Ogawa, H, Cornelius, F, Toyoshima, C. | 登録日 | 2008-12-22 | 公開日 | 2009-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the sodium - potassium pump at 2.4 A resolution Nature, 459, 2009
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2XZB
| Pig Gastric H,K-ATPase with bound BeF and SCH28080 | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | 著者 | Abe, K, Tani, K, Fujiyoshi, Y. | 登録日 | 2010-11-24 | 公開日 | 2011-01-26 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7 Å) | 主引用文献 | Conformational Rearrangement of Gastric H(+),K(+)- ATPase Induced by an Acid Suppressant. Nat.Commun., 2, 2011
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2ZBF
| Calcium pump crystal structure with bound BeF3 and TG in the absence of calcium | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | 著者 | Toyoshima, C, Ogawa, H, Norimatsu, Y. | 登録日 | 2007-10-20 | 公開日 | 2007-12-11 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
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