7TMY
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5KLT
| Prototypical P4[M]cNLS | 分子名称: | Importin subunit alpha-1, Prototypical P4[M]cNLS | 著者 | Smith, K.M, Forwood, J.K. | 登録日 | 2016-06-25 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting. Biochim Biophys Acta Mol Cell Res, 1865, 2018
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7UMI
| Importin a1 bound to Cp183-CTD | 分子名称: | HBV-NLS, Importin subunit alpha-1 | 著者 | Yang, R, Cingolani, G. | 登録日 | 2022-04-07 | 公開日 | 2023-10-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
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5IZA
| Protein-protein interaction | 分子名称: | ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2, Adenomatous polyposis coli protein | 著者 | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | 登録日 | 2016-03-25 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
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5KLR
| Prototypical P4[R]cNLS | 分子名称: | Importin subunit alpha-1, Prototypical P4[R]cNLS | 著者 | Smith, K.M, Forwood, J.K. | 登録日 | 2016-06-25 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting. Biochim Biophys Acta Mol Cell Res, 1865, 2018
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1EE4
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1BK6
| KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS | 分子名称: | KARYOPHERIN ALPHA, LARGE T ANTIGEN | 著者 | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | 登録日 | 1998-07-14 | 公開日 | 1999-01-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell(Cambridge,Mass.), 94, 1998
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1BK5
| KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE | 分子名称: | COBALT (II) ION, KARYOPHERIN ALPHA | 著者 | Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. | 登録日 | 1998-07-14 | 公開日 | 1999-01-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell(Cambridge,Mass.), 94, 1998
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1EJL
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1EE5
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5IZ9
| Protein-protein interaction | 分子名称: | ACE-GLY-GLY-GLU-ALA-LEU-ALA-ASP-NH2, Adenomatous polyposis coli protein | 著者 | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | 登録日 | 2016-03-25 | 公開日 | 2017-07-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
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7VPS
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7VPT
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5IZ6
| Protein-protein interaction | 分子名称: | Adenomatous polyposis coli protein, DI(HYDROXYETHYL)ETHER, PHQ-ALA-GLY-GLU-ALA-LEU-TYR-GLU-NH2, ... | 著者 | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | 登録日 | 2016-03-25 | 公開日 | 2017-07-05 | 最終更新日 | 2024-04-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration. Nat. Chem. Biol., 13, 2017
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1EJY
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1F59
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5H2X
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5H43
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5GXW
| Importin and NuMA complex | 分子名称: | Importin subunit alpha-1, Peptide from Nuclear mitotic apparatus protein 1 | 著者 | Chang, C.-C, Huang, T.-L, Hsia, K.-C. | 登録日 | 2016-09-20 | 公開日 | 2017-10-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | 主引用文献 | Regulation of mitotic spindle assembly factor NuMA by Importin-beta J. Cell Biol., 216, 2017
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5H2W
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5X8N
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6BW0
| Nipah virus W protein C-terminus in complex with Importin alpha 1 | 分子名称: | Importin subunit alpha-1, Protein W | 著者 | Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | 登録日 | 2017-12-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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6BWB
| Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3 | 分子名称: | Importin subunit alpha-3, Protein W | 著者 | Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | 登録日 | 2017-12-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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6BVT
| Importin alpha 1 in cargo free state | 分子名称: | Importin subunit alpha-1 | 著者 | Smith, K.M, Tsimablyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K. | 登録日 | 2017-12-13 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses. Nat Commun, 9, 2018
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5XZX
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