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7TMY
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BU of 7tmy by Molmil
Structure of Mouse Importin alpha NEIL3 NLS Peptide Complex
分子名称: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 3
著者Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
登録日2022-01-20
公開日2023-08-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
5KLT
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Prototypical P4[M]cNLS
分子名称: Importin subunit alpha-1, Prototypical P4[M]cNLS
著者Smith, K.M, Forwood, J.K.
登録日2016-06-25
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018
7UMI
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BU of 7umi by Molmil
Importin a1 bound to Cp183-CTD
分子名称: HBV-NLS, Importin subunit alpha-1
著者Yang, R, Cingolani, G.
登録日2022-04-07
公開日2023-10-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.
Sci Adv, 10, 2024
5IZA
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BU of 5iza by Molmil
Protein-protein interaction
分子名称: ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2, Adenomatous polyposis coli protein
著者Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J.
登録日2016-03-25
公開日2017-07-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
5KLR
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BU of 5klr by Molmil
Prototypical P4[R]cNLS
分子名称: Importin subunit alpha-1, Prototypical P4[R]cNLS
著者Smith, K.M, Forwood, J.K.
登録日2016-06-25
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.
Biochim Biophys Acta Mol Cell Res, 1865, 2018
1EE4
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BU of 1ee4 by Molmil
CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE
分子名称: KARYOPHERIN ALPHA, MYC PROTO-ONCOGENE PROTEIN
著者Conti, E.
登録日2000-01-30
公開日2000-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
1BK6
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BU of 1bk6 by Molmil
KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS
分子名称: KARYOPHERIN ALPHA, LARGE T ANTIGEN
著者Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
登録日1998-07-14
公開日1999-01-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1BK5
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BU of 1bk5 by Molmil
KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
分子名称: COBALT (II) ION, KARYOPHERIN ALPHA
著者Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
登録日1998-07-14
公開日1999-01-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
1EJL
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MOUSE IMPORTIN ALPHA-SV40 LARGE T ANTIGEN NLS PEPTIDE COMPLEX
分子名称: IMPORTIN ALPHA, SV40 LARGE T ANTIGEN NLS PEPTIDE
著者Fontes, M.R, Teh, T, Kobe, B.
登録日2000-03-03
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1EE5
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YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE
分子名称: KARYOPHERIN ALPHA, NUCLEOPLASMIN
著者Conti, E.
登録日2000-01-30
公開日2000-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha.
Structure Fold.Des., 8, 2000
5IZ9
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BU of 5iz9 by Molmil
Protein-protein interaction
分子名称: ACE-GLY-GLY-GLU-ALA-LEU-ALA-ASP-NH2, Adenomatous polyposis coli protein
著者Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J.
登録日2016-03-25
公開日2017-07-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
7VPS
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BU of 7vps by Molmil
Crystal structure of the ARM domain of C. glabrata importin alpha
分子名称: Importin subunit alpha
著者Tan, L, Im, Y.J.
登録日2021-10-17
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural basis for activation of fungal sterol receptor Upc2 and azole resistance.
Nat.Chem.Biol., 18, 2022
7VPT
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BU of 7vpt by Molmil
Structure of the C. glabrata importin alpha ARM domain - Upc2 NLS fusion
分子名称: C. glabrata importin alpha ARM domain - Upc2 NLS fusion
著者Tan, L, Im, Y.J.
登録日2021-10-18
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for activation of fungal sterol receptor Upc2 and azole resistance.
Nat.Chem.Biol., 18, 2022
5IZ6
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BU of 5iz6 by Molmil
Protein-protein interaction
分子名称: Adenomatous polyposis coli protein, DI(HYDROXYETHYL)ETHER, PHQ-ALA-GLY-GLU-ALA-LEU-TYR-GLU-NH2, ...
著者Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J.
登録日2016-03-25
公開日2017-07-05
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
1EJY
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BU of 1ejy by Molmil
MOUSE IMPORTIN ALPHA-NUCLEOPLASMIN NLS PEPTIDE COMPLEX
分子名称: IMPORTIN ALPHA, NUCLEOPLASMIN NLS PEPTIDE
著者Fontes, M.R, Teh, T, Kobe, B.
登録日2000-03-05
公開日2000-04-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-alpha.
J.Mol.Biol., 297, 2000
1F59
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BU of 1f59 by Molmil
IMPORTIN-BETA-FXFG NUCLEOPORIN COMPLEX
分子名称: FXFG NUCLEOPORIN REPEATS, IMPORTIN BETA-1
著者Bayliss, R, Littlewood, T, Stewart, M.
登録日2000-06-13
公開日2000-08-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the interaction between FxFG nucleoporin repeats and importin-beta in nuclear trafficking.
Cell(Cambridge,Mass.), 102, 2000
5H2X
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BU of 5h2x by Molmil
Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-172)
分子名称: Importin subunit alpha, Ubiquitin-like-specific protease 1
著者Hirano, H, Matsuura, Y.
登録日2016-10-18
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p
J. Mol. Biol., 429, 2017
5H43
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BU of 5h43 by Molmil
Structural and mechanistical studies of the nuclear import by Importin-alpha
分子名称: Histone acetyltransferase KAT8, Importin subunit alpha-1
著者Wang, R, Li, Y.
登録日2016-10-28
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin alpha 1
Traffic, 19, 2018
5GXW
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BU of 5gxw by Molmil
Importin and NuMA complex
分子名称: Importin subunit alpha-1, Peptide from Nuclear mitotic apparatus protein 1
著者Chang, C.-C, Huang, T.-L, Hsia, K.-C.
登録日2016-09-20
公開日2017-10-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Regulation of mitotic spindle assembly factor NuMA by Importin-beta
J. Cell Biol., 216, 2017
5H2W
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BU of 5h2w by Molmil
Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-340)
分子名称: Importin subunit alpha, Ubiquitin-like-specific protease 1
著者Hirano, H, Matsuura, Y.
登録日2016-10-18
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the Karyopherins Kap121p and Kap60p Bound to the Nuclear Pore-Targeting Domain of the SUMO Protease Ulp1p
J. Mol. Biol., 429, 2017
5X8N
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BU of 5x8n by Molmil
Crystal structure of mouse importin-alpha1 bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein
分子名称: Epstein-Barr nuclear antigen leader protein, Importin subunit alpha-1
著者Nakada, R, Matsuura, Y.
登録日2017-03-03
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of importin-alpha bound to the nuclear localization signal of Epstein-Barr virus EBNA-LP protein
Protein Sci., 26, 2017
6BW0
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BU of 6bw0 by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 1
分子名称: Importin subunit alpha-1, Protein W
著者Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BWB
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BU of 6bwb by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
6BVT
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BU of 6bvt by Molmil
Importin alpha 1 in cargo free state
分子名称: Importin subunit alpha-1
著者Smith, K.M, Tsimablyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-13
公開日2018-07-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
5XZX
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BU of 5xzx by Molmil
Crystal structure of importin-alpha3 bound to the nuclear localization signal of Ran-binding protein 3
分子名称: Importin subunit alpha-3, Ran-binding protein 3
著者Koyama, M, Matsuura, Y.
登録日2017-07-14
公開日2017-08-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of importin-alpha 3 bound to the nuclear localization signal of Ran-binding protein 3
Biochem. Biophys. Res. Commun., 491, 2017

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