PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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7Y97	Crystal structure of CYP109B4 from Bacillus Sonorensis 分子名称: Cytochrome P450 monooxygenase YjiB, PROTOPORPHYRIN IX CONTAINING FE 著者 Shen, P.P, Huang, J.-W, Li, X, Liu, W.D, Chen, C.-C, Guo, R.-T. 登録日 2022-06-24 公開日 2023-05-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Rationally Controlling Selective Steroid Hydroxylation via Scaffold Sampling of a P450 Family Acs Catalysis, 13, 2023
8A8L	Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with a heme-coordinated fragment 分子名称: 6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, Cytochrome P450 protein, GLYCEROL, ... 著者 Snee, M, Katariya, M, Levy, C. 登録日 2022-06-23 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with a heme-coordinated fragment To Be Published
8A6W	Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone 分子名称: (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, PROTOPORPHYRIN IX CONTAINING FE, Steroid C26-monooxygenase 著者 Snee, M, Amadi, C, Levy, C. 登録日 2022-06-20 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with cholestenone To Be Published
8D8P	Crystal structure of a novel fatty acid decarboxylase from Rothia nasimurium 分子名称: Decarboxylase, PALMITIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Vieira, P.S, Murakami, M.T, Zanphorlin, L.M. 登録日 2022-06-08 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of a novel fatty acid decarboxylase from Rothia nasimurium Proc.Natl.Acad.Sci.USA, 2023
7Y0S	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-TYR-TYR, ... 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-tyrosyl-L-tyrosine and hydroxylamine To Be Published
7Y0R	Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine 分子名称: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, 4-METHYLANILINE, Bifunctional cytochrome P450/NADPH--P450 reductase, ... 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structure of the P450 BM3 heme domain mutant F87L/V78S/A184V in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-toluidine and hydroxylamine To Be Published
7Y0T	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, I7X-PHE-PHE, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Anchoring a Structurally Editable Proximal Cofactor-like Module to Construct an Artificial Dual-center Peroxygenase. Angew.Chem.Int.Ed.Engl., 62, 2023
7Y0Q	Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with p-toluidine 分子名称: 4-METHYLANILINE, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with p-toluidine To Be Published
7Y0P	Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine 分子名称: (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, ... 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Crystal structure of the P450 BM3 heme domain mutant F87A/T268V/A82T/I263L in complex with N-imidazolyl-hexanoyl-L-phenylalanine, p-cresol and hydroxylamine To Be Published
7Y0U	Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, HYDROXYAMINE, I7X-PHE-PHE, ... 著者 Jiang, Y, Dong, S, Feng, Y, Cong, Z. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanyl-L-phenylalanine and hydroxylamine To Be Published
7XZK	Crystal Structure of P450BM3 with N-(3-cyclohexylpropanoyl)-L-pipecolyl-L-phenylalanine 分子名称: (2~{S})-2-[[(2~{S})-1-(3-cyclohexylpropanoyl)piperidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Shoji, O, Yonemura, K. 登録日 2022-06-02 公開日 2023-06-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Crystal Structure of P450BM3 with N-(3-cyclohexylpropanoyl)-L-pipecolyl-L-phenylalanine To Be Published
8D39	The crystal structure of WT CYP199A4 bound to 4-benzoylbenzoic acid 分子名称: 4-benzoylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-06-01 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.268 Å) 主引用文献 Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
8D1C	Crystal structure of T252E-CYP199A4 in complex with 4-(Trifluoromethoxy)benzoic acid 分子名称: 4-(trifluoromethoxy)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Lee, J.H.Z, Bruning, J.B, Bell, S.G. 登録日 2022-05-27 公開日 2023-03-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Selective Oxidations Using a Cytochrome P450 Enzyme Variant Driven with Surrogate Oxygen Donors and Light. Chemistry, 28, 2022
7ZZL	Crystal structure of CYP106A1 分子名称: COBALT (II) ION, Cytochrome P450, DI(HYDROXYETHYL)ETHER, ... 著者 Carius, Y, Kiss, F, Hutter, M, Bernhardt, R, Lancaster, C.R.D. 登録日 2022-05-25 公開日 2023-04-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural comparison of the cytochrome P450 enzymes CYP106A1 and CYP106A2 provides insight into their differences in steroid conversion. Febs Lett., 596, 2022
7ZXD	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: 1-[1-(2-piperidin-4-ylethyl)-5-pyridin-4-yl-indol-2-yl]butan-1-one, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Snee, M, Katariya, M, Levy, C, Leys, D. 登録日 2022-05-20 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7ZSU	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, Steroid C26-monooxygenase, ... 著者 Snee, M, Katariya, M, Levy, C, Leys, D. 登録日 2022-05-09 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7ZT0	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: 1-(2-piperazin-1-ylethyl)-5-pyridin-4-yl-indole-2-carboxamide, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Snee, M, Katariya, M, Levy, C, Leys, D. 登録日 2022-05-09 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7UWP	Detergent-bound CYP51 from Acanthamoeba castellanii 分子名称: DODECYL-BETA-D-MALTOSIDE, PROTOPORPHYRIN IX CONTAINING FE, sterol 14a-demethylase 著者 Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2022-05-03 公開日 2023-04-12 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Identification of Potent and Selective Inhibitors of Acanthamoeba: Structural Insights into Sterol 14-Demethylase as a Key Drug Target J.Med.Chem., 2024
7ZQR	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: 4-(4-methoxyphenyl)pyridine, CHLORIDE ION, GLYCEROL, ... 著者 Snee, M, Katariya, M, Tunnicliffe, R, Levy, C, Leys, D. 登録日 2022-05-02 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7ZLZ	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, Steroid C26-monooxygenase, ... 著者 Snee, M, Katariya, M, Levy, C, Leys, D. 登録日 2022-04-17 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7ZLT	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... 著者 Snee, M, Kavanagh, M, Levy, C. 登録日 2022-04-15 公開日 2023-05-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor To Be Published
7UOR	Crystal structure of cytochrome P450 enzyme CYP119 in complex with methyliridium(III) mesoporphyrin. 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome, NICKEL (II) ION, ... 著者 Pereira, J.H, Bloomer, B.J, Hartwig, J.F, Adams, P.D. 登録日 2022-04-13 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Mechanistic and structural characterization of an iridium-containing cytochrome reveals kinetically relevant cofactor dynamics Nat Catal, 6, 2023
7ZIC	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: CHLORIDE ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Snee, M, Levy, C, Kavanagh, M. 登録日 2022-04-07 公開日 2023-04-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor To Be Published
7ZGL	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Snee, M, Levy, C, Kavanagh, M. 登録日 2022-04-04 公開日 2023-04-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor To Be Published
7ZB9	Crystal structure of CYP124 in complex with inhibitor carbethoxyhexyl imidazole in the absence of glycerol (NoCryo) 分子名称: CHLORIDE ION, CYP124 in complex with inhibitor carbethoxyhexyl imidazole, MAGNESIUM ION, ... 著者 Bukhdruker, S, Varaksa, T, Marin, E, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2022-03-23 公開日 2023-01-11 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structural insights into the effects of glycerol on ligand binding to cytochrome P450. Acta Crystallogr D Struct Biol, 79, 2023

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