PDB: 1008 件ウェブページステータス検索Chemie searchBIRD

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2G78	Crystal Structure of the R132K:Y134F Mutant of Cellular Retinoic Acid Binding Protein Type II in Complex with All-Trans-Retinoic Acid at 1.70 Angstroms Resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINOIC ACID, SODIUM ION 著者 Vaezeslami, S, Geiger, J.H. 登録日 2006-02-27 公開日 2007-04-17 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007
6LJV	Crystal structure of human FABP4 in complex with a novel inhibitor 分子名称: 2-[[3-chloranyl-2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]amino]benzoic acid, Fatty acid-binding protein, adipocyte 著者 Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.401 Å) 主引用文献 Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
6E51	Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51W mutant of human cellular retinol binding protein II 分子名称: Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-07-19 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.256 Å) 主引用文献 Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141, 2019
6E50	Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51F mutant of human Cellular Retinol Binding Protein II 分子名称: ACETATE ION, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-07-18 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.965 Å) 主引用文献 Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141, 2019
2G7B	Crystal Structure of the R132K:R111L:L121E mutant of Cellular Retinoic Acid Binding Protein Type II In Complex With All-Trans-Retinal At 1.18 Angstroms Resolution 分子名称: ALL-TRANS AXEROPHTHENE, Cellular retinoic acid-binding protein 2, SODIUM ION 著者 Vaezeslami, S, Geiger, J.H. 登録日 2006-02-27 公開日 2007-04-17 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Protein design: reengineering cellular retinoic acid binding protein II into a rhodopsin protein mimic. J.Am.Chem.Soc., 129, 2007
6LJW	Crystal structure of human FABP4 in complex with a novel inhibitor 分子名称: 1,2-ETHANEDIOL, 2-phenylazanylbenzoic acid, Fatty acid-binding protein, ... 著者 Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
6LJT	Crystal structure of human FABP4 in complex with a novel inhibitor 分子名称: 1,2-ETHANEDIOL, 2-[(3-chloranyl-2-phenyl-phenyl)amino]benzoic acid, Fatty acid-binding protein, ... 著者 Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
6E5R	Crystal structure of the apo domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II 分子名称: ACETATE ION, GLYCEROL, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-07-22 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.592 Å) 主引用文献 Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141, 2019
6E7M	Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II 分子名称: ACETATE ION, GLYCEROL, RETINAL, ... 著者 Ghanbarpour, A, Geiger, J. 登録日 2018-07-26 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches. J.Am.Chem.Soc., 141, 2019
6L7K	solution structure of hIFABP V60C/Y70C variant. 分子名称: Fatty acid-binding protein, intestinal 著者 Fan, J, Yang, D. 登録日 2019-11-01 公開日 2020-11-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Ligand Entry into Fatty Acid Binding Protein via Local Unfolding Instead of Gap Widening. Biophys.J., 118, 2020
6VIT	The Crystal Structure of Apo Domain-Swapped dimer Q108K:T51D:I32C Variant of HCRBPII with an Engineered Disulfide Bond 分子名称: Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2020-01-13 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020
6VID	The Crystal Structure of Aps Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F Variant of HCRBPII 分子名称: ACETATE ION, GLYCEROL, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2020-01-12 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 The Crystal Structure of Apo Domain Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F variant of HCRBPII To Be Published
6VIS	The Crystal Structure of Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:V62E Variant of HCRBPII 分子名称: GLYCEROL, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2020-01-13 公開日 2020-09-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020
8GEW	H-FABP crystal soaked in a bromo palmitic acid solution 分子名称: 2-Bromopalmitic acid, Fatty acid-binding protein, heart, ... 著者 Howard, E, Cousido-Siah, A, Alvarez, A, Espinosa, Y, Podjarny, A, Mitschler, A, Carlevaro, M. 登録日 2023-03-07 公開日 2023-08-30 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (0.97 Å) 主引用文献 Lipid exchange in crystal-confined fatty acid binding proteins: X-ray evidence and molecular dynamics explanation. Proteins, 91, 2023
8GEU	Crystal structure of human cellular retinol binding protein 1 in complex with methyl({3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}methyl)[(1-methylpyrazol-4-yl)methyl]amine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-methyl-1-{3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}-N-[(1-methyl-1H-pyrazol-4-yl)methyl]methanamine, Retinol-binding protein 1 著者 Plau, J, Golczak, M. 登録日 2023-03-07 公開日 2023-10-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms. Acs Chem.Biol., 18, 2023
8GDM	Crystal structure of human cellular retinol binding protein 1 in complex with {[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}(methyl)[1-(thiophen-2-yl)ethyl]amine 分子名称: (1S)-N-{[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}-N-methyl-1-(thiophen-2-yl)ethan-1-amine, Retinol-binding protein 1 著者 Plau, J, Golczak, M. 登録日 2023-03-06 公開日 2023-10-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms. Acs Chem.Biol., 18, 2023
8GEV	Crystal structure of human cellular retinol binding protein 1 in complex with 1-{[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}-4-(methoxymethyl)piperidine 分子名称: 1-{[3-(diphenylmethyl)-1,2,4-oxadiazol-5-yl]methyl}-4-(methoxymethyl)piperidine, Retinol-binding protein 1 著者 Plau, J, Golczak, M. 登録日 2023-03-07 公開日 2023-10-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms. Acs Chem.Biol., 18, 2023
8GEM	Crystal structure of human cellular retinol binding protein 1 in complex with N-ethyl-N-({3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}methyl)-2-(1H-pyrazol-1-yl)ethanamine 分子名称: N-ethyl-N-({3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}methyl)-2-(1H-pyrazol-1-yl)ethan-1-amine, Retinol-binding protein 1 著者 Plau, J, Golczak, M. 登録日 2023-03-07 公開日 2023-10-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms. Acs Chem.Biol., 18, 2023
8GEY	Crystal structure of human cellular retinol binding protein 1 in complex with 4-(hydroxymethyl)-1-[(4-methoxy-5,6,7,8-tetrahydronaphthalen-1-yl)sulfonyl]piperidin-4-ol 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(hydroxymethyl)-1-(4-methoxy-5,6,7,8-tetrahydronaphthalene-1-sulfonyl)piperidin-4-ol, Retinol-binding protein 1 著者 Plau, J, Golczak, M. 登録日 2023-03-07 公開日 2023-10-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms. Acs Chem.Biol., 18, 2023
8GD2	Crystal structure of human cellular retinol binding protein 1 in complex with N-methyl-1-{3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}-N-(2-thienylmethyl)methanamine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-methyl-1-{3-[1-(4-methylphenyl)cyclopentyl]-1,2,4-oxadiazol-5-yl}-N-[(thiophen-2-yl)methyl]methanamine, Retinol-binding protein 1 著者 Plau, J, Golczak, M. 登録日 2023-03-03 公開日 2023-10-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Discovery of Nonretinoid Inhibitors of CRBP1: Structural and Dynamic Insights for Ligand-Binding Mechanisms. Acs Chem.Biol., 18, 2023
4WBK	The 1.37 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with stearic acid 分子名称: Fatty acid-binding protein, heart, STEARIC ACID 著者 Sugiyama, S, Matsuoka, S, Mizohata, E, Matsuoka, D, Murakami, S, Inoue, T, Murata, M. 登録日 2014-09-03 公開日 2015-01-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Molecular Dynamics Simulations of Heart-type Fatty Acid Binding Protein in Apo and Holo Forms, and Hydration Structure Analyses in the Binding Cavity J.Phys.Chem.B, 119, 2015
6WNF	The Crystal Structure of Apo Domain-Swapped Dimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII 分子名称: ACETATE ION, GLYCEROL, Retinol-binding protein 2 著者 Ghanbarpour, A, Geiger, J. 登録日 2020-04-22 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020
6WNJ	The Crystal Structure of Apo Domain-Swapped Trimer Q108K:T51D:A28C:I32C of HCRBPII 分子名称: GLYCEROL, Retinol-binding protein 2, SULFATE ION, ... 著者 Ghanbarpour, A, Geiger, J. 登録日 2020-04-22 公開日 2020-08-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human Cellular Retinol Binding Protein II Forms a Domain-Swapped Trimer Representing a Novel Fold and a New Template for Protein Engineering. Chembiochem, 21, 2020
8HTA	Solution Structure of the C65A/C167A Mutant of Human Lipocalin-type Prostaglandin D Synthase 分子名称: Prostaglandin-H2 D-isomerase 著者 Miyamoto, Y, Inui, T. 登録日 2022-12-20 公開日 2023-04-19 最終更新日 2023-08-30 実験手法 SOLUTION NMR 主引用文献 Structural and interaction analysis of human lipocalin-type prostaglandin D synthase with the poorly water-soluble drug NBQX. Febs J., 290, 2023
2WUT	Crystal structure of human myelin protein P2 in complex with palmitate 分子名称: CHLORIDE ION, GLYCEROL, MYELIN P2 PROTEIN, ... 著者 Majava, V, Nanekar, R, Kursula, P. 登録日 2009-10-09 公開日 2010-05-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and Functional Characterization of Human Peripheral Nervous System Myelin Protein P2. Plos One, 5, 2010

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