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7ZGK
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Trypanosoma brucei gambiense ISG65 in complex with human complement component C3b
分子名称: 65 kDa invariant surface glycoprotein, putative, Complement C3 beta chain, ...
著者Suelzen, H, Zoll, S.
登録日2022-04-03
公開日2023-04-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Nat Commun, 14, 2023
7NRZ
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Crystal structure of malate dehydrogenase from Trypanosoma cruzi
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Sonani, R.R, Kurpiewska, K, Lewinski, K, Dubin, G.
登録日2021-03-04
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Distinct sequence and structural feature of trypanosoma malate dehydrogenase.
Biochem.Biophys.Res.Commun., 557, 2021
8B3W
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Structure of metacyclic VSG (mVSG) 1954 from Trypanosoma brucei
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Variant surface glycoprotein 1954
著者Chandra, M, Stebbins, C.E.
登録日2022-09-17
公開日2023-01-25
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (1.681 Å)
主引用文献Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Plos Negl Trop Dis, 17, 2023
8B3B
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Structure of metacyclic VSG (mVSG) 531 from Trypanosoma brucei
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 531, alpha-D-mannopyranose, ...
著者Chandra, M, Stebbins, C.E.
登録日2022-09-16
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Plos Negl Trop Dis, 17, 2023
4DWB
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Crystal structure of Trypanosoma cruzi farnesyl diphosphate synthase in complex with [2-(n-pentylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ACETATE ION, Farnesyl pyrophosphate synthase, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.B.
登録日2012-02-24
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
J.Med.Chem., 55, 2012
6TLI
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THERMOLYSIN (60% ISOPROPANOL SOAKED CRYSTALS)
分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
著者English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
登録日1998-10-29
公開日2000-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
5KLH
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Crystal Structure of Trypanosoma brucei Procyclic Specific Surface Antigen-2
分子名称: SULFATE ION, Surface glycoprotein
著者Ramaswamy, R, Parker, M.L, Boulanger, M.J.
登録日2016-06-24
公開日2017-07-05
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.646 Å)
主引用文献Structural characterization reveals a novel bilobed architecture for the ectodomains of insect stage expressed Trypanosoma brucei PSSA-2 and Trypanosoma congolense ISA.
Protein Sci., 25, 2016
6PTI
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STRUCTURE OF FORM III CRYSTALS OF BOVINE PANCREATIC TRYPSIN INHIBITOR
分子名称: PANCREATIC TRYPSIN INHIBITOR PRECURSOR, PHOSPHATE ION
著者Wlodawer, A.
登録日1987-05-13
公開日1987-10-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of form III crystals of bovine pancreatic trypsin inhibitor.
J.Mol.Biol., 198, 1987
2GTD
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Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria
分子名称: Type III Pantothenate Kinase
著者Yang, K, Eyobo, Y, Brand, A.L, Martynowski, D, Tomchick, D.
登録日2006-04-27
公開日2006-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria.
J.Bacteriol., 188, 2006
2ZJX
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Bovine pancreatic trypsin inhibitor (BPTI) containing only the [5,55] disulfide bond
分子名称: Pancreatic trypsin inhibitor, SULFATE ION
著者Islam, M.M, Sohya, S, Noguchi, K, Yohda, M, Kuroda, Y.
登録日2008-03-11
公開日2008-10-21
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines
Proc.Natl.Acad.Sci.Usa, 105, 2008
6XYB
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Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi
分子名称: CHLORIDE ION, IODIDE ION, MAGNESIUM ION, ...
著者Roske, Y, Heinemann, U.
登録日2020-01-30
公開日2020-06-10
最終更新日2020-07-15
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.
J.Struct.Biol., 211, 2020
6MD3
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Structure of T. brucei RRP44 PIN domain
分子名称: CHLORIDE ION, MANGANESE (II) ION, Rrp44p homologue, ...
著者Guimaraes, B.G, Cesaro, G.
登録日2018-09-03
公開日2019-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Trypanosoma brucei RRP44 is involved in an early stage of large ribosomal subunit RNA maturation.
RNA Biol, 16, 2019
3ND6
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Crystal structure of phosphopantetheine adenylyltransferase (PPAT) in complex with ATP from Enterococcus faecalis
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Phosphopantetheine adenylyltransferase
著者Yoon, H.J, Lee, H.H, Suh, S.W.
登録日2010-06-07
公開日2011-06-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine
Mol.Cells, 32, 2011
6AIP
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Cab2 mutant-H337A complex with phosphopantothenoylcystine
分子名称: (5R,12R,17R)-17-amino-12-carboxy-1,1,5-trihydroxy-4,4-dimethyl-6,10-dioxo-2-oxa-14,15-dithia-7,11-diaza-1-phosphaoctadecan-18-oic acid 1-oxide (non-preferred name), Phosphopantothenate--cysteine ligase CAB2
著者Zheng, P, Zhu, Z.
登録日2018-08-24
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae.
J. Mol. Biol., 431, 2019
6SOY
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Trypanosoma brucei transferrin receptor in complex with human transferrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, subunit of heterodimeric transferrin receptor, ...
著者Trevor, C, Carrington, M, Higgins, M.K.
登録日2019-08-30
公開日2019-11-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol, 4, 2019
8AP8
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Peripheral stalk of Trypanosoma brucei mitochondrial ATP synthase
分子名称: ATPTB3, ATPTB4, OSCP, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8AP7
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membrane region of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8AP9
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rotor of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: ATP synthase gamma subunit, ATP synthase subunit epsilon, mitochondrial, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APC
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rotational state 1c of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APF
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rotational state 2a of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APD
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rotational state 1d of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APH
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BU of 8aph by Molmil
rotational state 2c of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APJ
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rotational state 2d of Trypanosoma brucei mitochondrial ATP synthase
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APA
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rotational state 1a of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APB
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rotational state 1b of the Trypanosoma brucei mitochondrial ATP synthase dimer
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
著者Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
登録日2022-08-09
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022

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