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8CBJ
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BU of 8cbj by Molmil
Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex
分子名称: 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ...
著者Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2023-01-25
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
6KWY
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BU of 6kwy by Molmil
human PA200-20S complex
分子名称: INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ...
著者Ouyang, S, Hongxin, G.
登録日2019-09-09
公開日2020-04-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures.
Plos Biol., 18, 2020
2DYH
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BU of 2dyh by Molmil
Crystal structure of the Keap1 protein in complexed with the N-terminal region of the Nrf2 transcription factor
分子名称: Kelch-like ECH-associated protein 1, Nrf2/Neh2 peptide from Nuclear factor erythroid 2-related factor 2, SULFATE ION
著者Padmanabhan, B, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-09-14
公開日2007-09-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
Mol.Cell.Biol., 27, 2007
4WB8
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BU of 4wb8 by Molmil
Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit), exon 1 deletion
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A.
登録日2014-09-02
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
2NTE
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BU of 2nte by Molmil
Crystal Structure of the BARD1 BRCT Domains
分子名称: 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ...
著者Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A.
登録日2006-11-07
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
2G45
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BU of 2g45 by Molmil
Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin
分子名称: CHLORIDE ION, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 5, ...
著者Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D.
登録日2006-02-21
公開日2006-04-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin.
Cell(Cambridge,Mass.), 124, 2006
2G43
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Structure of the ZNF UBP domain from deubiquitinating enzyme isopeptidase T (IsoT)
分子名称: UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ZINC ION
著者Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D.
登録日2006-02-21
公開日2006-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin.
Cell(Cambridge,Mass.), 124, 2006
6GHS
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BU of 6ghs by Molmil
Modification dependent TagI restriction endonuclease
分子名称: SODIUM ION, TagI restriction endonuclease, ZINC ION
著者Kisiala, M, Copelas, A, Czapinska, H, Xu, S, Bochtler, M.
登録日2018-05-08
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Crystal structure of the modification-dependent SRA-HNH endonuclease TagI.
Nucleic Acids Res., 46, 2018
8CAH
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BU of 8cah by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2023-01-24
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
5A5H
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BU of 5a5h by Molmil
The crystal structure of the GST-like domains complex of EPRS C92SC105SC123S mutant-AIMP2
分子名称: AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONA L PROTEIN 2, BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE
著者Cho, H.Y, Kang, B.S.
登録日2015-06-18
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.318 Å)
主引用文献The Crystal Structure of the Gst-Like Domains Complex of Eprs C92Sc105Sc123S Mutant-Aimp2
To be Published
5CLQ
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BU of 5clq by Molmil
Ran Y39A in complex with GPPNHP and RanBD1
分子名称: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者Vetter, I.R, Brucker, S.
登録日2015-07-16
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy.
J.Biol.Chem., 290, 2015
8AGW
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BU of 8agw by Molmil
Yeast RQC complex in state D
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
3ONH
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BU of 3onh by Molmil
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways
分子名称: Ubiquitin-activating enzyme E1-like
著者Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A.
登録日2010-08-28
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.
Plos One, 5, 2010
7D8R
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BU of 7d8r by Molmil
MITF HLHLZ structure
分子名称: Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit
著者Guo, M, Fang, P, Wang, J.
登録日2020-10-09
公開日2021-10-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
7D8S
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BU of 7d8s by Molmil
MITF bHLHLZ apo structure
分子名称: Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit, SULFATE ION
著者Guo, M, Fang, P, Wang, J.
登録日2020-10-09
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy.
Cell Res., 33, 2023
8B6F
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BU of 8b6f by Molmil
Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ...
著者Muhleip, A, Kock Flygaard, R, Amunts, A.
登録日2022-09-27
公開日2023-03-29
最終更新日2023-04-12
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
8AGT
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BU of 8agt by Molmil
Yeast RQC complex in state F
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGX
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BU of 8agx by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the IN position
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGZ
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BU of 8agz by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AAF
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BU of 8aaf by Molmil
Yeast RQC complex in state G
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-01
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGV
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BU of 8agv by Molmil
Yeast RQC complex in state H
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGU
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BU of 8agu by Molmil
Yeast RQC complex in state E
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
3ONG
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BU of 3ong by Molmil
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways
分子名称: SUMO-conjugating enzyme UBC9, Ubiquitin-activating enzyme E1-like
著者Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A.
登録日2010-08-28
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.
Plos One, 5, 2010
3U5P
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BU of 3u5p by Molmil
Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-28)K9me3K14acK18acK23ac histone peptide
分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2011-10-11
公開日2012-01-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
3U5N
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BU of 3u5n by Molmil
Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-20)K9me3K14ac histone peptide
分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2011-10-11
公開日2012-01-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A Poised Chromatin Platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011

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