8CBJ
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![BU of 8cbj by Molmil](/molmil-images/mine/8cbj) | Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex | 分子名称: | 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-25 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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6KWY
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![BU of 6kwy by Molmil](/molmil-images/mine/6kwy) | human PA200-20S complex | 分子名称: | INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ... | 著者 | Ouyang, S, Hongxin, G. | 登録日 | 2019-09-09 | 公開日 | 2020-04-01 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.72 Å) | 主引用文献 | Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures. Plos Biol., 18, 2020
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2DYH
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![BU of 2dyh by Molmil](/molmil-images/mine/2dyh) | |
4WB8
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![BU of 4wb8 by Molmil](/molmil-images/mine/4wb8) | Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit), exon 1 deletion | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. | 登録日 | 2014-09-02 | 公開日 | 2015-01-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural insights into mis-regulation of protein kinase A in human tumors. Proc.Natl.Acad.Sci.USA, 112, 2015
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2NTE
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![BU of 2nte by Molmil](/molmil-images/mine/2nte) | Crystal Structure of the BARD1 BRCT Domains | 分子名称: | 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ... | 著者 | Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A. | 登録日 | 2006-11-07 | 公開日 | 2007-06-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the BARD1 BRCT domains. Biochemistry, 46, 2007
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2G45
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![BU of 2g45 by Molmil](/molmil-images/mine/2g45) | Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin | 分子名称: | CHLORIDE ION, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 5, ... | 著者 | Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D. | 登録日 | 2006-02-21 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin. Cell(Cambridge,Mass.), 124, 2006
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2G43
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![BU of 2g43 by Molmil](/molmil-images/mine/2g43) | Structure of the ZNF UBP domain from deubiquitinating enzyme isopeptidase T (IsoT) | 分子名称: | UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ZINC ION | 著者 | Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D. | 登録日 | 2006-02-21 | 公開日 | 2006-04-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin. Cell(Cambridge,Mass.), 124, 2006
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6GHS
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![BU of 6ghs by Molmil](/molmil-images/mine/6ghs) | Modification dependent TagI restriction endonuclease | 分子名称: | SODIUM ION, TagI restriction endonuclease, ZINC ION | 著者 | Kisiala, M, Copelas, A, Czapinska, H, Xu, S, Bochtler, M. | 登録日 | 2018-05-08 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Crystal structure of the modification-dependent SRA-HNH endonuclease TagI. Nucleic Acids Res., 46, 2018
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8CAH
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![BU of 8cah by Molmil](/molmil-images/mine/8cah) | Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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5A5H
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![BU of 5a5h by Molmil](/molmil-images/mine/5a5h) | |
5CLQ
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![BU of 5clq by Molmil](/molmil-images/mine/5clq) | Ran Y39A in complex with GPPNHP and RanBD1 | 分子名称: | E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ... | 著者 | Vetter, I.R, Brucker, S. | 登録日 | 2015-07-16 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy. J.Biol.Chem., 290, 2015
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8AGW
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![BU of 8agw by Molmil](/molmil-images/mine/8agw) | Yeast RQC complex in state D | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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3ONH
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![BU of 3onh by Molmil](/molmil-images/mine/3onh) | Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways | 分子名称: | Ubiquitin-activating enzyme E1-like | 著者 | Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A. | 登録日 | 2010-08-28 | 公開日 | 2011-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways. Plos One, 5, 2010
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7D8R
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![BU of 7d8r by Molmil](/molmil-images/mine/7d8r) | MITF HLHLZ structure | 分子名称: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit | 著者 | Guo, M, Fang, P, Wang, J. | 登録日 | 2020-10-09 | 公開日 | 2021-10-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
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7D8S
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![BU of 7d8s by Molmil](/molmil-images/mine/7d8s) | MITF bHLHLZ apo structure | 分子名称: | Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit, SULFATE ION | 著者 | Guo, M, Fang, P, Wang, J. | 登録日 | 2020-10-09 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
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8B6F
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![BU of 8b6f by Molmil](/molmil-images/mine/8b6f) | Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... | 著者 | Muhleip, A, Kock Flygaard, R, Amunts, A. | 登録日 | 2022-09-27 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex. Nature, 615, 2023
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8AGT
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![BU of 8agt by Molmil](/molmil-images/mine/8agt) | Yeast RQC complex in state F | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGX
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![BU of 8agx by Molmil](/molmil-images/mine/8agx) | Yeast RQC complex in state with the RING domain of Ltn1 in the IN position | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGZ
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![BU of 8agz by Molmil](/molmil-images/mine/8agz) | Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AAF
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![BU of 8aaf by Molmil](/molmil-images/mine/8aaf) | Yeast RQC complex in state G | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-01 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGV
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![BU of 8agv by Molmil](/molmil-images/mine/8agv) | Yeast RQC complex in state H | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGU
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![BU of 8agu by Molmil](/molmil-images/mine/8agu) | Yeast RQC complex in state E | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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3ONG
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![BU of 3ong by Molmil](/molmil-images/mine/3ong) | Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways | 分子名称: | SUMO-conjugating enzyme UBC9, Ubiquitin-activating enzyme E1-like | 著者 | Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A. | 登録日 | 2010-08-28 | 公開日 | 2011-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways. Plos One, 5, 2010
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3U5P
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![BU of 3u5p by Molmil](/molmil-images/mine/3u5p) | |
3U5N
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![BU of 3u5n by Molmil](/molmil-images/mine/3u5n) | |