PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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6XFJ	Crystal structure of the type III secretion pilotin InvH 分子名称: CADMIUM ION, CHLORIDE ION, SODIUM ION, ... 著者 Majewski, D.D, Okon, M, Heinkel, F, Robb, C.S, Vuckovic, M, McIntosh, L.P, Strynadka, N.C.J. 登録日 2020-06-15 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods. Structure, 29, 2021
4USN	The structure of the immature HIV-1 capsid in intact virus particles at sub-nm resolution 分子名称: P24 著者 Schur, F.K.M, Hagen, W.J.H, Rumlova, M, Ruml, T, Mueller, B, Kraeusslich, H.-G, Briggs, J.A.G. 登録日 2014-07-11 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.8 Å) 主引用文献 Structure of the Immature HIV-1 Capsid in Intact Virus Particles at 8.8 A Resolution. Nature, 517, 2015
6XWJ	Constitutive decay element CDE2 from human 3'UTR 分子名称: RNA (5'-R(*GP*GP*UP*GP*CP*CP*UP*AP*AP*UP*AP*UP*UP*UP*AP*GP*GP*CP*AP*CP*C)-3') 著者 Schwalbe, H, Binas, O. 登録日 2020-01-23 公開日 2020-05-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis for the recognition of transiently structured AU-rich elements by Roquin. Nucleic Acids Res., 48, 2020
6V94	Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods 分子名称: 1-[(4-fluorophenyl)methyl]-2-methyl-4-nitro-1H-imidazole, FORMIC ACID, GLYCEROL, ... 著者 Phan, J, Fesik, S.W. 登録日 2019-12-13 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020
4USA	Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with trans-cinnamaldehyde 分子名称: (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... 著者 Correia, H.D, Romao, M.J, Santos-Silva, T. 登録日 2014-07-03 公開日 2014-10-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction. J.Biol.Inorg.Chem., 20, 2015
6V9J	Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods 分子名称: 3-(2-aminoethyl)-4-(3-chloro-4-fluorophenoxy)benzene-1-sulfonamide, FORMIC ACID, GLYCEROL, ... 著者 Phan, J, Fesik, S.W. 登録日 2019-12-13 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020
8IIZ	Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K27ac peptide 分子名称: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ... 著者 Kikuchi, M, Umehara, T. 登録日 2023-02-24 公開日 2023-11-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
4UR9	Structure of ligand bound glycosylhydrolase 分子名称: 4-ethoxyquinazoline, CALCIUM ION, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE, ... 著者 Darby, J.F, Landstroem, J, Roth, C, He, Y, Schultz, M, Davies, G.J, Hubbard, R.E. 登録日 2014-06-27 公開日 2015-02-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of Selective Small-Molecule Activators of a Bacterial Glycoside Hydrolase. Angew.Chem.Int.Ed.Engl., 53, 2014
8IIY	Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide 分子名称: GLYCEROL, Histone H3.1, Maltodextrin-binding protein,YEATS domain-containing protein 4, ... 著者 Kikuchi, M, Umehara, T. 登録日 2023-02-24 公開日 2023-11-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
8IJ0	Crystal structure of GAS41 YEATS domain in complex with H3K9ac peptide 分子名称: GLYCEROL, Histone H3.1, PENTAETHYLENE GLYCOL, ... 著者 Kikuchi, M, Umehara, T. 登録日 2023-02-24 公開日 2023-11-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proc.Natl.Acad.Sci.USA, 120, 2023
4UY1	Novel pyrazole series of group X Secretory Phospholipase A2 (sPLA2-X) inhibitors 分子名称: 5-(2,5-DIMETHYL-3-THIENYL)-1H-PYRAZOLE-3-CARBOXAMIDE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Sandmark, J, Oster, L, Hallberg, K, Bodin, C, Chen, H. 登録日 2014-08-28 公開日 2014-10-15 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of a Novel Pyrazole Series of Group X Secreted Phospholipase A2 Inhibitor (Spla2X) Via Fragment Based Virtual Screening Bioorg.Med.Chem.Lett., 24, 2014
4V8O	Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3 分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Jin, H, Kelley, A.C, Ramakrishnan, V. 登録日 2011-07-26 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Crystal Structure of the Hybrid State of Ribosome in Complex with the Guanosine Triphosphatase Release Factor 3. Proc.Natl.Acad.Sci.USA, 108, 2011
4V9G	RC-LH1-PufX dimer complex from Rhodobacter sphaeroides 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ... 著者 Qian, P, Papiz, M.Z, Jackson, P.J, Brindley, A.A, Ng, I.W, Olsen, J.D, Dickman, M.J, Bullough, P.A, Hunter, C.N. 登録日 2013-02-21 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (7.78 Å) 主引用文献 Three-Dimensional Structure of the Rhodobacter sphaeroides RC-LH1-PufX Complex: Dimerization and Quinone Channels Promoted by PufX. Biochemistry, 52, 2013
6V9M	Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods 分子名称: 4-fluoro-2-methyl-N-propylbenzene-1-sulfonamide, FORMIC ACID, GLYCEROL, ... 著者 Phan, J, Fesik, S.W. 登録日 2019-12-13 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.648 Å) 主引用文献 Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020
6V9F	Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods 分子名称: 1-[(4-chlorophenyl)methyl]-1H-benzimidazol-2-amine, FORMIC ACID, GLYCEROL, ... 著者 Phan, J, Fesik, S.W. 登録日 2019-12-13 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020
6V9L	Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods 分子名称: 4-(3-chloro-4-fluorophenoxy)benzene-1-sulfonamide, ACETATE ION, FORMIC ACID, ... 著者 Phan, J, Fesik, S.W. 登録日 2019-12-13 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. J.Med.Chem., 63, 2020
8BRO	Structure of the N-terminal domain of BC2L-C lectin (1-131) in complex with a synthetic beta-fucosylamide 分子名称: 5-[3-(aminomethyl)phenyl]-~{N}-[(2~{S},3~{S},4~{R},5~{S},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]furan-2-carboxamide, Lectin 著者 Varrot, A, Lunstrom, J. 登録日 2022-11-23 公開日 2023-02-08 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Identification of New L-Fucosyl and L-Galactosyl Amides as Glycomimetic Ligands of TNF Lectin Domain of BC2L-C from Burkholderia cenocepacia. Molecules, 28, 2023
5GXG	High-resolution crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Kikui, Y, Hiruma, Y, Ubbink, M, Nojiri, M. 登録日 2016-09-17 公開日 2017-01-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Identification of productive and futile encounters in an electron transfer protein complex Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8BOG	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 7 分子名称: Ephrin type-A receptor 2, ~{N}-[4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]phenyl]-3-(trifluoromethyl)benzamide 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
8BOM	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 14 分子名称: Ephrin type-A receptor 2, ~{N}-(3-methoxyphenyl)-4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
8BOH	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 8 分子名称: 4-methyl-~{N}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide, Ephrin type-A receptor 2 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
8BOD	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 20 分子名称: Ephrin type-A receptor 2, ~{N}-[3,5-bis(chloranyl)phenyl]-4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
8BOI	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 9 分子名称: 4-methyl-~{N}-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide, Ephrin type-A receptor 2 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
8BOK	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 11 分子名称: Ephrin type-A receptor 2, ~{N}-(3,5-dimethoxyphenyl)-4-methyl-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
8BOF	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 12 分子名称: 4-methyl-~{N}-(3-methylphenyl)-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide, Ephrin type-A receptor 2 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023

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