PDB: 97310 件ウェブページステータス検索Chemie searchBIRD

---

7ZV5	Crystal structure of SARS Cov-2 main protease in complex with an inhibitor 4 分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, inhibitor TRIP5 著者 Rahimova, R, Di Micco, S, Marquez, J.A. 登録日 2022-05-13 公開日 2022-11-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2. Eur.J.Med.Chem., 244, 2022
8JUH	Crystal structure of ScFv against the receptor binding domine of SARS-CoV-2 S-spike protein 分子名称: Single chain fab antibody 著者 Ma, Q.Q, Su, Z.D. 登録日 2023-06-26 公開日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of ScFv against the receptor binding domine of SARS-CoV-2 S-spike protein To Be Published
3OGP	Crystal Structure of 6s-98S FIV Protease with Darunavir bound 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, DIMETHYL SULFOXIDE, FIV Protease 著者 Lin, Y.-C, Perryman, A.L, Elder, J.H, Stout, C.D. 登録日 2010-08-17 公開日 2011-06-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease. Acta Crystallogr.,Sect.D, 67, 2011
3OJL	Native structure of the UDP-N-acetyl-mannosamine dehydrogenase Cap5O from Staphylococcus aureus 分子名称: Cap5O, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Nessler, S, Gruszczyk, J, Olivares-Illana, V, Meyer, P, Morera, S, Grangeasse, C, Fleurie, A. 登録日 2010-08-23 公開日 2011-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure Analysis of the Staphylococcus aureus UDP-N-acetyl-mannosamine Dehydrogenase Cap5O Involved in Capsular Polysaccharide Biosynthesis. J.Biol.Chem., 286, 2011
6GVM	Tubulin:F3II DARPin complex 分子名称: F3II DARPIN, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Gigant, B, Campanacci, V, Cantos Fernandes, S. 登録日 2018-06-21 公開日 2019-04-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Insight into microtubule nucleation from tubulin-capping proteins. Proc.Natl.Acad.Sci.USA, 116, 2019
2PHH	THE COENZYME ANALOGUE ADENOSINE 5-DIPHOSPHORIBOSE DISPLACES FAD IN THE ACTIVE SITE OF P-HYDROXYBENZOATE HYDROXYLASE. AN X-RAY CRYSTALLOGRAPHIC INVESTIGATION 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID 著者 Van Derlaan, J.M, Drenth, J, Hol, W.G.J. 登録日 1989-06-19 公開日 1990-10-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The coenzyme analogue adenosine 5-diphosphoribose displaces FAD in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation. Biochemistry, 28, 1989
8D6J	Human Ago2 bound to miR122(21nt) with PIWI loop swapped to AtAgo10 sequence 分子名称: MAGNESIUM ION, Protein argonaute-2, RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3') 著者 Xiao, Y, MacRae, I. 登録日 2022-06-06 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24, 2023
3JYP	Quinate dehydrogenase from Corynebacterium glutamicum in complex with quinate and NADH 分子名称: (1S,3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Quinate/shikimate dehydrogenase 著者 Hoeppner, A, Schomburg, D, Niefind, K. 登録日 2009-09-22 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination. Biol.Chem., 394, 2013
3OIQ	Crystal structure of yeast telomere protein Cdc13 OB1 and the catalytic subunit of DNA polymerase alpha Pol1 分子名称: Cell division control protein 13, DNA polymerase alpha catalytic subunit A 著者 Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. 登録日 2010-08-19 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha. Cell Res., 21, 2011
4LAD	Crystal Structure of the Ube2g2:RING-G2BR complex 分子名称: E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... 著者 Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. 登録日 2013-06-19 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine. Embo J., 32, 2013
8KGZ	Crystal structure of single-chain Fv antibody against antigen peptide from SARS-CoV2 S-spike protein 分子名称: Thioredoxin 1,scFv 著者 Ma, Q.Q, Zhang, B.L, Cheng, X.Y, Huang, Y.Q, Su, Z.D. 登録日 2023-08-20 公開日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal structure of sheep scFv antibody against an antigen peptide of SARS-CoV2 S-spike protein To Be Published
8D71	Human Ago2 bound to miR122(21nt) 分子名称: MAGNESIUM ION, Protein argonaute-2, miR-122-21nt 著者 Xiao, Y, MacRae, I. 登録日 2022-06-07 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24, 2023
3K47	Alternate Binding Modes Observed for the E- and Z-Isomers of 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase 分子名称: 5-[(1E)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Pace, J, Queener, S.F, Gangjee, A. 登録日 2009-10-05 公開日 2009-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors. Bioorg.Med.Chem., 17, 2009
5FOY	De novo structure of the binary mosquito larvicide BinAB at pH 7 分子名称: 41.9 KDA INSECTICIDAL TOXIN, LARVICIDAL TOXIN 51 KDA PROTEIN 著者 Colletier, J.P, Sawaya, M.R, Gingery, M, Rodriguez, J.A, Cascio, D, Brewster, A.S, Michels-Clark, T, Boutet, S, Williams, G.J, Messerschmidt, M, DePonte, D.P, Sierra, R.G, Laksmono, H, Koglin, J.E, Hunter, M.S, W Park, H, Uervirojnangkoorn, M, Bideshi, D.L, Brunger, A.T, Federici, B.A, Sauter, N.K, Eisenberg, D.S. 登録日 2015-11-26 公開日 2016-10-05 最終更新日 2019-08-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 De Novo Phasing with X-Ray Laser Reveals Mosquito Larvicide Binab Structure. Nature, 539, 2016
8DA3	Coevolved affibody-Z domain pair LL1.c1 分子名称: Affibody LL1.FILF, Immunoglobulin G-binding protein A, MALONATE ION, ... 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DA9	Coevolved affibody-Z domain pair LL2.c3 分子名称: Affibody LL2.FIIV, GLYCEROL, Immunoglobulin G-binding protein A, ... 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DA4	Coevolved affibody-Z domain pair LL1.c2 分子名称: Affibody LL1.FIVM, Immunoglobulin G-binding protein A, SULFATE ION, ... 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DA6	Coevolved affibody-Z domain pair LL1.c5 分子名称: Affibody LL1.FIIM, Immunoglobulin G-binding protein A 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DA5	Coevolved affibody-Z domain pair LL1.c4 分子名称: GLYCEROL, Immunoglobulin G-binding protein A, affibody LL1.FIVM 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DA7	Coevolved affibody-Z domain pair LL1.c6 分子名称: Immunoglobulin G-binding protein A, MALONATE ION, affibody LL1.FIFV 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DA8	Coevolved affibody-Z domain pair LL2.c1 分子名称: Affibody LL2.FIIK, GLYCEROL, Immunoglobulin G-binding protein A 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DAC	Coevolved affibody-Z domain pair LL2.c22 分子名称: Affibody LL2.FILV, GLYCEROL, Immunoglobulin G-binding protein A 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DAB	Coevolved affibody-Z domain pair LL2.c17 分子名称: Affibody LL2.IVVY, Immunoglobulin G-binding protein A 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.134 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
8DAA	Coevolved affibody-Z domain pair LL2.c7 分子名称: Affibody LL2.FIVK, Immunoglobulin G-binding protein A, MALONATE ION 著者 Jude, K.M, Yang, A, Garcia, K.C. 登録日 2022-06-13 公開日 2023-07-26 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Science, 381, 2023
5DDM	Human DNA polymerase lambda- Apoenzyme and complex with 6 paired DNA 分子名称: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ... 著者 Liu, M.S, Tsai, M.D. 登録日 2015-08-25 公開日 2016-02-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda J.Am.Chem.Soc., 138, 2016

<565566567568569570571572573574575576577578579580>