1HV5
 
 | | CRYSTAL STRUCTURE OF THE STROMELYSIN-3 (MMP-11) CATALYTIC DOMAIN COMPLEXED WITH A PHOSPHINIC INHIBITOR | | 分子名称: | 1-BENZYLOXYCARBONYLAMINO-2-PHENYL-ETHYL)-{2-[1-CARBAMOYL-2-(1H-INDOL-3-YL)-ETHYLCARBAMOYL]-5-PHENYL-PENTYL}-PHOSPHINIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ... | | 著者 | Gall, A.L, Ruff, M, Kannan, R, Cuniasse, P, Yiotakis, A, Dive, V, Rio, M.C, Basset, P, Moras, D. | | 登録日 | 2001-01-08 | | 公開日 | 2001-03-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state.
J.Mol.Biol., 307, 2001
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1DKH
 | | CRYSTAL STRUCTURE OF THE HEMOPHORE HASA, PH 6.5 | | 分子名称: | HEME-BINDING PROTEIN A, PROTOPORPHYRIN IX CONTAINING FE, SAMARIUM (III) ION, ... | | 著者 | Arnoux, P, Haser, R, Izadi-Pruneyre, N, Lecroisey, A, Czjzek, M. | | 登録日 | 1999-12-07 | | 公開日 | 2000-12-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Functional aspects of the heme bound hemophore HasA by structural analysis of various crystal forms.
Proteins, 41, 2000
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5L1M
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7XX9
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7XX8
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3LFF
 | | Human p38 MAP Kinase in Complex with RL166 | | 分子名称: | (4-{3-tert-butyl-5-[(1,3-thiazol-2-ylcarbamoyl)amino]-1H-pyrazol-1-yl}phenyl)acetic acid, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. | | 登録日 | 2010-01-16 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha
To be Published
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2YVR
 | | Crystal structure of MS1043 | | 分子名称: | Transcription intermediary factor 1-beta, ZINC ION | | 著者 | Wang, H, Kishishita, S, Murayama, K, Takemoto, C, Terada, T, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-13 | | 公開日 | 2008-04-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of MS1043
To be Published
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5KRH
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 16-benzylidene estrone | | 分子名称: | (8~{R},9~{S},13~{S},14~{S},16~{E})-13-methyl-3-oxidanyl-16-(phenylmethylidene)-6,7,8,9,11,12,14,15-octahydrocyclopenta[ a]phenanthren-17-one, Estrogen receptor, NCOA2 | | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Nowak, J, Kojetin, D.J, Elemento, O, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2016-07-07 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.243 Å) | | 主引用文献 | Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
Cell Chem Biol, 24, 2017
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7YG6
 | | Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA | | 分子名称: | MAGNESIUM ION, Piwi, piRNA | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-11 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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3LFE
 | | Human p38 MAP Kinase in Complex with RL116 | | 分子名称: | 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(pyridin-4-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. | | 登録日 | 2010-01-16 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha
To be Published
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7YGN
 | | Cryo-EM structure of the Mili in complex with piRNA | | 分子名称: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-11 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFX
 | | Cryo-EM structure of Hili in complex with piRNA | | 分子名称: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-09 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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1I55
 | | CYTOCHROME C (TUNA) WITH 2ZN:1FE MIXED-METAL PORPHYRINS | | 分子名称: | CYTOCHROME C, HEME C, PROTOPORPHYRIN IX CONTAINING ZN | | 著者 | Crane, B.R, Tezcan, F.A, Winkler, J.R, Gray, H.B. | | 登録日 | 2001-02-24 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Electron tunneling in protein crystals.
Proc.Natl.Acad.Sci.USA, 98, 2001
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5HJ7
 | | Glutamate Racemase Mycobacterium tuberculosis (MurI) with bound D-glutamate, 2.3 Angstrom resolution, X-ray diffraction | | 分子名称: | D-GLUTAMIC ACID, Glutamate racemase | | 著者 | Poen, S, Nakatani, Y, Krause, K. | | 登録日 | 2016-01-12 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery.
Biochem. J., 473, 2016
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3LLM
 | | Crystal Structure Analysis of a RNA Helicase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase A, CACODYLATE ION, ... | | 著者 | Schutz, P, Karlberg, T, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H.M, Structural Genomics Consortium (SGC) | | 登録日 | 2010-01-29 | | 公開日 | 2010-05-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of human RNA helicase A (DHX9): structural basis for unselective nucleotide base binding in a DEAD-box variant protein.
J.Mol.Biol., 400, 2010
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7YFQ
 | | Cryo-EM structure of the EfPiwi (N959K)-piRNA-target ternary complex | | 分子名称: | MAGNESIUM ION, Piwi, RNA (5'-R(*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*AP*A)-3'), ... | | 著者 | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | 登録日 | 2022-07-08 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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2Y8G
 | | Structure of the Ran-binding domain from human RanBP3 (E352A-R353V double mutant) | | 分子名称: | RAN-BINDING PROTEIN 3, SULFATE ION | | 著者 | Langer, K, Dian, C, Rybin, V, Muller, C.W, Petosa, C. | | 登録日 | 2011-02-06 | | 公開日 | 2011-02-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Insights Into the Function of the Crm1 Cofactor Ranbp3 from the Structure of its Ran-Binding Domain
Plos One, 6, 2011
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6TWM
 | | Product bound structure of the Ectoine utilization protein EutE (DoeB) from Ruegeria pomeroyi | | 分子名称: | 2,4-DIAMINOBUTYRIC ACID, ACETATE ION, N-acetyl-L-2,4-diaminobutyric acid deacetylase, ... | | 著者 | Mais, C.-N, Altegoer, F, Bange, G. | | 登録日 | 2020-01-13 | | 公開日 | 2020-05-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex.
J.Biol.Chem., 295, 2020
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1SSL
 | | Solution structure of the PSI domain from the Met receptor | | 分子名称: | Hepatocyte growth factor receptor | | 著者 | Kozlov, G, Perreault, A, Schrag, J.D, Cygler, M, Gehring, K, Ekiel, I. | | 登録日 | 2004-03-24 | | 公開日 | 2004-10-12 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into function of PSI domains from structure of the Met receptor PSI domain.
Biochem.Biophys.Res.Commun., 321, 2004
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2YQ7
 | | Structure of Bcl-xL bound to BimLOCK | | 分子名称: | BCL-2-LIKE PROTEIN 1, BCL-2-LIKE PROTEIN 11, GLYCEROL | | 著者 | Smith, B.J, Czabotar, P.E. | | 登録日 | 2012-11-06 | | 公開日 | 2012-11-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity.
Acs Chem.Biol., 8, 2013
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2YQQ
 | | Solution structure of the zf-HIT domain in zinc finger HIT domain-containing protein 3 (TRIP-3) | | 分子名称: | ZINC ION, Zinc finger HIT domain-containing protein 3 | | 著者 | Suzuki, S, He, F, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-30 | | 公開日 | 2007-10-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the zf-HIT domain in zinc finger HIT domain-containing protein 3 (TRIP-3)
To be Published
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4GHU
 | | Crystal structure of TRAF3/Cardif | | 分子名称: | Mitochondrial antiviral-signaling protein, TNF receptor-associated factor 3 | | 著者 | Zhang, P. | | 登録日 | 2012-08-08 | | 公開日 | 2012-11-28 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
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3LFD
 | | Human p38 MAP Kinase in Complex with RL113 | | 分子名称: | 1-{4-[2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. | | 登録日 | 2010-01-16 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha
To be Published
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2YW8
 | | Crystal structure of human RUN and FYVE domain-containing protein | | 分子名称: | RUN and FYVE domain-containing protein 1, SULFATE ION, ZINC ION | | 著者 | Wang, H, Kishishita, S, Murayama, K, Takemoto, C, Terada, T, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-20 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human RUN and FYVE domain-containing protein
To be Published
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5L7S
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