3MGH
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![BU of 3mgh by Molmil](/molmil-images/mine/3mgh) | Binary complex of a DNA polymerase lambda loop mutant | 分子名称: | DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(P*GP*CP*CP*G)-3'), ... | 著者 | Garcia-Diaz, M, Bebenek, K, Zhou, R.Z, Povirk, L.F, Kunkel, T. | 登録日 | 2010-04-06 | 公開日 | 2010-05-19 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Loop 1 modulates the fidelity of DNA polymerase lambda Nucleic Acids Res., 38, 2010
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6MES
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3QZF
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![BU of 3qzf by Molmil](/molmil-images/mine/3qzf) | CDK2 in complex with inhibitor JWS-6-52 | 分子名称: | 2-(4,6-diamino-1,3,5-triazin-2-yl)benzene-1,4-diol, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-06 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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6LXX
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![BU of 6lxx by Molmil](/molmil-images/mine/6lxx) | Frog EPDR1 with an Ir atom | 分子名称: | CALCIUM ION, CHLORIDE ION, Ependymin-related 1, ... | 著者 | Park, S, Park, J. | 登録日 | 2020-02-12 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Single Soaked Iridium (IV) Ion Observed in the Frog Ependymin-Related Protein. Bull.Korean Chem.Soc., 41, 2020
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6LYM
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![BU of 6lym by Molmil](/molmil-images/mine/6lym) | Crystal structure of D657A mutant of formylglycinamidine synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-14 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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6LYO
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![BU of 6lyo by Molmil](/molmil-images/mine/6lyo) | Crystal Structure of H296A mutant of Formylglycinamidine Synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-15 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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3RJ0
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6LYL
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![BU of 6lyl by Molmil](/molmil-images/mine/6lyl) | Crystal structure of S1052D mutant of Formylglycinamidine synthetase | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Sharma, N, Tanwar, A.S, Anand, R. | 登録日 | 2020-02-14 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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3R6X
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![BU of 3r6x by Molmil](/molmil-images/mine/3r6x) | CDK2 in complex with inhibitor KVR-1-158 | 分子名称: | 1,2-ETHANEDIOL, 4-[(3-hydroxypropyl)amino]-5-nitro-2-[(pyridin-3-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-22 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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3R7U
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![BU of 3r7u by Molmil](/molmil-images/mine/3r7u) | CDK2 in complex with inhibitor KVR-1-75 | 分子名称: | 1,2-ETHANEDIOL, 2-{[4-(aminomethyl)benzyl]amino}-5-nitrobenzamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-23 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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3R9H
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![BU of 3r9h by Molmil](/molmil-images/mine/3r9h) | CDK2 in complex with inhibitor RC-2-142 | 分子名称: | 4-amino-N-(2,6-difluorophenyl)-2-[(4-sulfamoylphenyl)amino]-1,3-thiazole-5-carboxamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-25 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
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6LZB
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![BU of 6lzb by Molmil](/molmil-images/mine/6lzb) | crystal structure of Human Methionine aminopeptidase (HsMetAP1b) in complex with AN-P2-5H-06 | 分子名称: | 1-[(3-methoxyphenyl)methyl]-~{N}-oxidanyl-pyrrolo[2,3-b]pyridine-5-carboxamide, COBALT (II) ION, GLYCEROL, ... | 著者 | sandeep, C.B, Addlagatta, A. | 登録日 | 2020-02-18 | 公開日 | 2021-02-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Selective inhibition of Helicobacter pylori methionine aminopeptidase by azaindole hydroxamic acid derivatives: Design, synthesis, in vitro biochemical and structural studies. Bioorg.Chem., 115, 2021
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6M0U
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3MQS
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![BU of 3mqs by Molmil](/molmil-images/mine/3mqs) | |
6M2Z
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![BU of 6m2z by Molmil](/molmil-images/mine/6m2z) | Crystal structure of a formolase, BFD variant M3 from Pseudomonas putida | 分子名称: | Benzoylformate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | 著者 | Wei, H.L, Liu, W.D, Li, T.Z, Zhu, L.L. | 登録日 | 2020-03-02 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediate. Green Chem, 22, 2020
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6M2Y
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![BU of 6m2y by Molmil](/molmil-images/mine/6m2y) | Crystal structure of a formolase, BFD variant M6 from Pseudomonas putida | 分子名称: | Benzoylformate decarboxylase, MAGNESIUM ION, THIAMINE DIPHOSPHATE | 著者 | Wei, H.L, Liu, W.D, Li, T.Z, Zhu, L.L. | 登録日 | 2020-03-02 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediate. Green Chem, 22, 2020
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6M4I
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3RPO
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![BU of 3rpo by Molmil](/molmil-images/mine/3rpo) | CDK2 in complex with inhibitor KVR-1-156 | 分子名称: | 1,2-ETHANEDIOL, 4-({4-carbamoyl-2-nitro-5-[(pyridin-3-ylmethyl)amino]phenyl}amino)butanoic acid, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-04-27 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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3MGM
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![BU of 3mgm by Molmil](/molmil-images/mine/3mgm) | Crystal structure of human NUDT16 | 分子名称: | U8 snoRNA-decapping enzyme | 著者 | Yan, J, Lu, G, Zhang, J, Qi, J, Li, Z, Gao, F. | 登録日 | 2010-04-07 | 公開日 | 2011-04-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Crystal structure and the template mRNA decapping activity of human NUDT16 To be Published
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3RPV
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![BU of 3rpv by Molmil](/molmil-images/mine/3rpv) | CDK2 in complex with inhibitor RC-2-88 | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-amino-5-(3-aminobenzoyl)-1,3-thiazol-2-yl]amino}benzenesulfonamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-04-27 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
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3LB9
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![BU of 3lb9 by Molmil](/molmil-images/mine/3lb9) | Crystal structure of the B. circulans cpA123 circular permutant | 分子名称: | Endo-1,4-beta-xylanase | 著者 | D'Angelo, I, Reitinger, S, Ludwiczek, M, Strynadka, N, Withers, S.G, Mcintosh, L.P. | 登録日 | 2010-01-08 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Circular permutation of Bacillus circulans xylanase: a kinetic and structural study. Biochemistry, 49, 2010
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3RQ7
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![BU of 3rq7 by Molmil](/molmil-images/mine/3rq7) | Polo-like kinase 1 Polo box domain in complex with a C6H5(CH2)8-derivatized peptide inhibitor | 分子名称: | C6H5(CH2)8-derivatized peptide inhibitor, Serine/threonine-protein kinase PLK1 | 著者 | Liu, F, Park, J.-E, Qian, W.-J, Lim, D.C, Graber, M, Berg, T, Yaffe, M.B, Lee, K.S, Burke Jr, T.R. | 登録日 | 2011-04-27 | 公開日 | 2011-07-20 | 最終更新日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel. Nat.Chem.Biol., 7, 2011
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6M5Y
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3R7V
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![BU of 3r7v by Molmil](/molmil-images/mine/3r7v) | CDK2 in complex with inhibitor KVR-1-9 | 分子名称: | 1,2-ETHANEDIOL, 5-nitro-2-[(pyridin-2-ylmethyl)amino]benzamide, Cyclin-dependent kinase 2 | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | 登録日 | 2011-03-23 | 公開日 | 2012-08-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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6M73
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![BU of 6m73 by Molmil](/molmil-images/mine/6m73) | Crystal structure of Enterococcus hirae L-lactate oxidase in complex with D-lactate form ligand | 分子名称: | 1,2-ETHANEDIOL, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Yoshida, H, Hiraka, K, Tsugawa, W, Sode, K. | 登録日 | 2020-03-16 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of lactate oxidase from Enterococcus hirae revealed new aspects of active site loop function: Product-inhibition mechanism and oxygen gatekeeper Protein Sci., 31, 2022
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