PDB: 73050 件ウェブページステータス検索Chemie searchBIRD

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7N9T	CryoEM structure of SARS-CoV-2 Spike in complex with Nb17 分子名称: Nanobody Nb17, Spike glycoprotein 著者 Huang, W, Taylor, D. 登録日 2021-06-18 公開日 2021-08-11 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes Nat Commun, 12, 2021
2I1K	Moesin from Spodoptera frugiperda reveals the coiled-coil domain at 3.0 angstrom resolution 分子名称: CHLORIDE ION, GLYCEROL, Moesin, ... 著者 Nance, M.R, Tesmer, J.J.G. 登録日 2006-08-14 公開日 2006-12-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain. J.Mol.Biol., 365, 2007
7N3U	Crystal structure of human WEE1 kinase domain in complex with ZN-c3 分子名称: 1-[(7R)-7-ethyl-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, Wee1-like protein kinase 著者 Lee, C.C. 登録日 2021-06-02 公開日 2021-09-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer. J.Med.Chem., 64, 2021
6Y7R	Structure of Chloroflexus aggregans Cagg_3753 LOV domain C85A A56P variant (CagFbFP) 分子名称: FLAVIN MONONUCLEOTIDE, Multi-sensor hybrid histidine kinase 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gordeliy, V, Gushchin, I. 登録日 2020-03-02 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Effects of Proline Substitutions on the Thermostable LOV Domain from Chloroflexus aggregans Crystals, 2020
8UEM	The CryoEM structure of the high affinity Carbon monoxide dehydrogenase from Mycobacterium smegmatis 分子名称: CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase (Large chain), CoxL, ... 著者 Grinter, R, Gillett, D. 登録日 2023-10-02 公開日 2024-10-16 実験手法 ELECTRON MICROSCOPY (1.85 Å) 主引用文献 Structural basis for bacterial energy extraction from atmospheric hydrogen To Be Published
1O61	Crystal structure of a PLP-dependent enzyme with PLP 分子名称: ACETATE ION, PYRIDOXAL-5'-PHOSPHATE, aminotransferase 著者 Structural GenomiX 登録日 2003-10-23 公開日 2003-11-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
8UDS	The Crystal Structure of CoxG from M. smegmatis, minus lipid anchoring C-terminus. 分子名称: Carbon monoxide dehydrogenase subunit G (CoxG) family protein 著者 Rhys, R, Kropp, A. 登録日 2023-09-29 公開日 2024-10-02 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for bacterial energy extraction from atmospheric carbon monoxide To Be Published
7N4N	BACE-2 in complex with ligand 36 分子名称: 1,2-ETHANEDIOL, Beta-secretase 2, N-{3-[(2S,5R)-6-amino-2-(fluoromethyl)-5-(methanesulfonyl)-5-methyl-2,3,4,5-tetrahydropyridin-2-yl]-4-fluorophenyl}-6-methoxypyrimidine-4-carboxamide, ... 著者 Shaffer, P.L. 登録日 2021-06-04 公開日 2021-10-06 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. J.Med.Chem., 64, 2021
7N66	BACE-1 in complex with ligand 12 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Shaffer, P.L. 登録日 2021-06-07 公開日 2021-10-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate. J.Med.Chem., 64, 2021
8RRW	Structure of RyR1 in detergent in open state in complex with FKBP and Nb9657. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... 著者 Li, C, Efremov, R.G. 登録日 2024-01-23 公開日 2024-10-09 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM. J.Biol.Chem., 300, 2024
8RRV	Structure of RyR1 in detergent in close state in complex with FKBP and Nb9657. 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION, ... 著者 Li, C, Efremov, R.G. 登録日 2024-01-23 公開日 2024-10-09 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM. J.Biol.Chem., 300, 2024
8RS0	Structure of RyR1 in detergent in primed state in complex with nanobody and FKBP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... 著者 Li, C, Efremov, R.G. 登録日 2024-01-24 公開日 2024-10-09 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Rapid small-scale nanobody-assisted purification of ryanodine receptors for cryo-EM. J.Biol.Chem., 300, 2024
1NRK	YGFZ PROTEIN 分子名称: SULFATE ION, YGFZ Protein 著者 Teplyakov, A, Obmolova, G, Gilliland, G.L, Structure 2 Function Project (S2F) 登録日 2003-01-24 公開日 2004-03-09 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the YgfZ protein from Escherichia coli suggests a folate-dependent regulatory role in one-carbon metabolism. J.Bacteriol., 186, 2004
2FH1	C-terminal half of gelsolin soaked in low calcium at pH 4.5 分子名称: CALCIUM ION, Gelsolin 著者 Chumnarnsilpa, S, Loonchanta, A, Xue, B, Choe, H, Urosev, D, Wang, H, Burtnick, L.D, Robinson, R.C. 登録日 2005-12-23 公開日 2006-06-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Calcium ion exchange in crystalline gelsolin J.Mol.Biol., 357, 2006
1O68	Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase 分子名称: 3-METHYL-2-OXOBUTANOIC ACID, 3-methyl-2-oxobutanoate hydroxymethyltransferase, SODIUM ION 著者 Structural GenomiX 登録日 2003-10-23 公開日 2003-11-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
1AZB	STRUCTURE OF APO-AZURIN FROM ALCALIGENES DENITRIFICANS AT 1.8 ANGSTROMS RESOLUTION 分子名称: AZURIN, COPPER (II) ION, SULFATE ION 著者 Baker, E.N, Shepard, W.E.B. 登録日 1992-12-16 公開日 1993-10-31 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of apo-azurin from Alcaligenes denitrificans at 1.8 A resolution. Acta Crystallogr.,Sect.D, 49, 1993
6YI8	HUMAN FGFR4 KINASE DOMAIN (447-753) IN COMPLEX WITH ROBLITINIB 分子名称: Fibroblast growth factor receptor 4, N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-methanoyl-6-[(4-methyl-2-oxidanylidene-piperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide, SULFATE ION 著者 Ostermann, N. 登録日 2020-04-01 公開日 2020-09-30 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4. J.Med.Chem., 63, 2020
1MAM	CRYSTAL STRUCTURE TO 2.45 A RESOLUTION OF A MONOCLONAL FAB SPECIFIC FOR THE BRUCELLA A CELL WALL POLYSACCHARIDE ANTIGEN 分子名称: IGG2B-KAPPA YST9.1 FAB (HEAVY CHAIN), IGG2B-KAPPA YST9.1 FAB (LIGHT CHAIN) 著者 Rose, D.R. 登録日 1992-01-14 公開日 1993-10-31 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure to 2.45 A resolution of a monoclonal Fab specific for the Brucella A cell wall polysaccharide antigen. Protein Sci., 2, 1993
1MTR	HIV-1 PROTEASE COMPLEXED WITH A CYCLIC PHE-ILE-VAL PEPTIDOMIMETIC INHIBITOR 分子名称: HIV-1 PROTEASE, SULFATE ION, [1-BENZYL-3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YLAMINO)-2-HYDROXY-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER 著者 Wickramasinghe, W, Begun, J, Martin, J.L. 登録日 1996-02-15 公開日 1996-08-01 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Substrate-based cyclic peptidomimetics of Phe-Ile-Val that inhibit HIV-1 protease using a novel enzyme-binding mode. J.Am.Chem.Soc., 118, 1996
6Y3U	Crystal structure of PPARgamma in complex with compound (R)-16 分子名称: (2~{R})-2-[[6-[(2,4-dichlorophenyl)sulfonylamino]-1,3-benzothiazol-2-yl]sulfanyl]octanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Chaikuad, A, Hanke, T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-02-18 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 A Selective Modulator of Peroxisome Proliferator-Activated Receptor gamma with an Unprecedented Binding Mode. J.Med.Chem., 63, 2020
2H9B	Crystal structure of the effector binding domain of a BenM variant (BenM R156H/T157S) 分子名称: CHLORIDE ION, HTH-type transcriptional regulator benM, SULFATE ION 著者 Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C. 登録日 2006-06-09 公開日 2007-06-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1. Mol.Microbiol., 72, 2009
6Y7U	Structure of Chloroflexus aggregans Cagg_3753 LOV domain C85A A95P variant (CagFbFP) 分子名称: FLAVIN MONONUCLEOTIDE, Multi-sensor hybrid histidine kinase 著者 Remeeva, A, Nazarenko, V, Kovalev, K, Gordeliy, V, Gushchin, I. 登録日 2020-03-02 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Effects of Proline Substitutions on the Thermostable LOV Domain from Chloroflexus aggregans Crystals, 2020
1MXR	High resolution structure of Ribonucleotide reductase R2 from E. coli in its oxidised (Met) form 分子名称: FE (III) ION, GLYCEROL, MERCURY (II) ION, ... 著者 Andersson, M.A, Hogbom, M, Nordlund, P. 登録日 2002-10-03 公開日 2003-03-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Displacement of the tyrosyl radical cofactor in ribonucleotide reductase obtained by single-crystal high-field EPR and 1.4-A x-ray data. Proc.Natl.Acad.Sci.Usa, 100, 2003
1N94	Aryl Tetrahydropyridine Inhbitors of Farnesyltransferase: Glycine, Phenylalanine and Histidine Derivates 分子名称: 2-{(5-{[BUTYL-(2-CYCLOHEXYL-ETHYL)-AMINO]-METHYL}-2'-METHYL-BIPHENYL-2-CARBONYL)-AMINO]-4-METHYLSULFANYL-BUTYRIC ACID, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ... 著者 Gwaltney II, S.L, O'Connor, S.J, Nelson, L.T, Sullivan, G.M, Imade, H, Wang, W, Hasvold, L, Li, Q, Cohen, J, Gu, W.Z. 登録日 2002-11-22 公開日 2003-01-07 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. Bioorg.Med.Chem.Lett., 13, 2003
2HI9	Crystal Structure of human native protein C inhibitor 分子名称: CITRIC ACID, GLYCEROL, Plasma serine protease inhibitor 著者 Li, W, Adams, T.E, Huntington, J.A. 登録日 2006-06-29 公開日 2007-03-13 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of native protein C inhibitor provides insight into its multiple functions. J.Biol.Chem., 282, 2007

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