PDB: 3575 件ウェブページステータス検索Chemie searchBIRD

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4W55	T4 Lysozyme L99A with n-Propylbenzene Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, propylbenzene 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6401 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
4W58	T4 Lysozyme L99A with n-Pentylbenzene Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, pentylbenzene 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
5T04	STRUCTURE OF CONSTITUTIVELY ACTIVE NEUROTENSIN RECEPTOR 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, ARG-ARG-PRO-TYR-ILE-LEU, DI(HYDROXYETHYL)ETHER, ... 著者 Krumm, B, Botos, I, Grisshammer, R. 登録日 2016-08-15 公開日 2016-12-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure and dynamics of a constitutively active neurotensin receptor. Sci Rep, 6, 2016
5TZY	GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R)-3-cyclopropyl-3-[(2R)-2-(1-{(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl}piperidin-4-yl)-3,4-dihydro-2H-1-benzopyran-7-yl]-2-methylpropanoic acid, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, ... 著者 Lu, J, Byrne, N, Patel, S, Sharma, S, Soisson, S.M. 登録日 2016-11-22 公開日 2017-06-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40. Nat. Struct. Mol. Biol., 24, 2017
2QB0	Structure of the 2TEL crystallization module fused to T4 lysozyme with an Ala-Gly-Pro linker. 分子名称: MANGANESE (II) ION, Transcription factor ETV6, Transcription factor ETV6,Endolysin 著者 Nauli, S, Bowie, J.U. 登録日 2007-06-15 公開日 2008-10-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Polymer-driven crystallization. Protein Sci., 16, 2007
8P3A	bacteriophage T5 l-alanoyl-d-glutamate peptidase Zn2+/Ca2+ form 分子名称: CALCIUM ION, L-alanyl-D-glutamate peptidase, ZINC ION 著者 Prokhorov, D.A, Kutyshenko, V.P, Mikoulinskaia, G.V. 登録日 2023-05-17 公開日 2023-07-05 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Mechanism of Ca2+-dependent activation of L-alanoyl-D-glutamate peptidase bacteriophage T5. To Be Published
7P2L	thermostabilised 7TM domain of human mGlu5 receptor bound to photoswitchable ligand alloswitch-1 分子名称: 2-chloranyl-~{N}-[2-methoxy-4-[(~{E})-pyridin-2-yldiazenyl]phenyl]benzamide, Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate receptor 5 著者 Huang, C.Y, Vinothkumar, K.R, Lebon, G. 登録日 2021-07-06 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36, 2021
7L3J	T4 Lysozyme L99A - benzylacetate - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3A	T4 Lysozyme L99A - toluene - cryo 分子名称: Endolysin, TOLUENE 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L39	T4 Lysozyme L99A - toluene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L38	T4 Lysozyme L99A - Apo - cryo 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L37	T4 Lysozyme L99A - Apo - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.439 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3B	T4 Lysozyme L99A - iodobenzene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3H	T4 Lysozyme L99A - ethylbenzene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3G	T4 Lysozyme L99A - 4-iodotoluene - cryo 分子名称: 1-iodo-4-methylbenzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3F	T4 Lysozyme L99A - 4-iodotoluene - RT 分子名称: 1-iodo-4-methylbenzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3K	T4 Lysozyme L99A - benzylacetate - cryo 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3C	T4 Lysozyme L99A - o-xylene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3E	T4 Lysozyme L99A - 3-iodotoluene - cryo 分子名称: 1-iodo-3-methylbenzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3D	T4 Lysozyme L99A - 3-iodotoluene - RT 分子名称: 1-iodo-3-methylbenzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3I	T4 Lysozyme L99A - propylbenzene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Endolysin, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
6KK7	Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain 分子名称: Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine 著者 Song, G. 登録日 2019-07-23 公開日 2019-11-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Mutagenesis facilitated crystallization of GLP-1R. Iucrj, 6, 2019
6KK1	Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain 分子名称: Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine 著者 Song, G. 登録日 2019-07-23 公開日 2019-11-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mutagenesis facilitated crystallization of GLP-1R. Iucrj, 6, 2019
6KJV	Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine 著者 Song, G. 登録日 2019-07-23 公開日 2019-11-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mutagenesis facilitated crystallization of GLP-1R. Iucrj, 6, 2019
6FFH	Crystal Structure of mGluR5 in complex with Fenobam at 2.65 A 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-(3-chlorophenyl)-3-(3-methyl-5-oxidanylidene-4~{H}-imidazol-2-yl)urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Christopher, J.A, Orgovan, Z, Congreve, M, Dore, A.S, Errey, J.C, Marshall, F.H, Mason, J.S, Okrasa, K, Rucktooa, P, Serrano-Vega, M.J, Ferenczy, G.G, Keseru, G.M. 登録日 2018-01-08 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures. J.Med.Chem., 62, 2019

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