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8X19
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Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
8X15
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Structure of nucleosome-bound SRCAP-C in the apo state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
4XLS
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Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream fork promoter.
分子名称: CarD-like transcriptional regulator, DNA (30-MER), DNA (5'-D(P*GP*CP*AP*CP*AP*AP*TP*TP*TP*AP*AP*CP*AP*CP*TP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3'), ...
著者Bae, B, Darst, S.A.
登録日2015-01-13
公開日2015-09-23
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.
Elife, 4, 2015
7N4E
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BU of 7n4e by Molmil
Escherichia coli sigma 70-dependent paused transcription elongation complex
分子名称: 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Molodtsov, V, Su, M, Ebright, R.H.
登録日2021-06-04
公開日2022-06-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural and mechanistic basis of sigma-dependent transcriptional pausing.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EHF
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Cryo-EM structure of his-elemental paused elongation complex with an unfolded TL (1)
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-14
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EG8
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BU of 8eg8 by Molmil
Cryo-EM structure of consensus elemental paused elongation complex with a folded TL
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-12
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EHA
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Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-14
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EGB
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Cryo-EM structure of consensus elemental paused elongation complex with an unfolded TL
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-12
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EG7
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BU of 8eg7 by Molmil
Cryo-EM structure of pre-consensus elemental paused elongation complex
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-11
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EH8
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BU of 8eh8 by Molmil
Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (1)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-13
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EH9
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BU of 8eh9 by Molmil
Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (2)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-13
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
6LE9
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BU of 6le9 by Molmil
The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ...
著者Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L.
登録日2019-11-24
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
8XVT
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BU of 8xvt by Molmil
The core subcomplex of human NuA4/TIP60 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Chen, K, Wang, L, Yu, Z, Yu, J, Ren, Y, Wang, Q, Xu, Y.
登録日2024-01-15
公開日2024-07-24
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the human TIP60 complex.
Nat Commun, 15, 2024
8BF8
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BU of 8bf8 by Molmil
ISDra2 TnpB in complex with reRNA
分子名称: Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB
著者Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D.
登録日2022-10-24
公開日2023-04-12
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
1IBX
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BU of 1ibx by Molmil
NMR STRUCTURE OF DFF40 AND DFF45 N-TERMINAL DOMAIN COMPLEX
分子名称: CHIMERA OF IGG BINDING PROTEIN G AND DNA FRAGMENTATION FACTOR 45, DNA FRAGMENTATION FACTOR 40
著者Zhou, P, Lugovskoy, A.A, McCarty, J.S, Li, P, Wagner, G.
登録日2001-03-29
公開日2001-05-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45.
Proc.Natl.Acad.Sci.USA, 98, 2001
5IPL
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BU of 5ipl by Molmil
SigmaS-transcription initiation complex with 4-nt nascent RNA
分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Zuo, Y, Steitz, T.A.
登録日2016-03-09
公開日2016-03-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
4YFK
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BU of 4yfk by Molmil
Escherichia coli RNA polymerase in complex with squaramide compound 8.
分子名称: 3,5-dimethyl-N-{2-[4-(4-methylbenzyl)piperidin-1-yl]-3,4-dioxocyclobut-1-en-1-yl}-1,2-oxazole-4-sulfonamide, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Molodtsov, V, Fleming, P.R, Eyermann, C.J, Ferguson, A.D, Foulk, M.A, McKinney, D.C, Masse, C.E, Buurman, E.T, Murakami, K.S.
登録日2015-02-25
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.571 Å)
主引用文献X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein.
J.Med.Chem., 58, 2015
8XVG
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BU of 8xvg by Molmil
Structure of human NuA4/TIP60 complex
分子名称: ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 6A, ...
著者Chen, K, Wang, L, Yu, Z, Yu, J, Ren, Y, Wang, Q, Xu, Y.
登録日2024-01-15
公開日2024-07-24
最終更新日2024-09-04
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Structure of the human TIP60 complex.
Nat Commun, 15, 2024
6B6H
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BU of 6b6h by Molmil
The cryo-EM structure of a bacterial class I transcription activation complex
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A.
登録日2017-10-02
公開日2017-11-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of bacterial transcription activation.
Science, 358, 2017
4U6K
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BU of 4u6k by Molmil
Crystal structure of DNA/RNA duplex containing 2'-4'-BNA-NC
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*(NCU)P*(NTT)P*CP*TP*TP*CP*TP*(NTT)P*(NCU))-3'), RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*G)-3')
著者Kondo, J, Nomura, Y, Kitahara, Y, Obika, S, Torigoe, H.
登録日2014-07-29
公開日2015-08-19
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of a 2',4'-BNA(NC)[N-Me]-modified antisense gapmer in complex with the target RNA.
Chem.Commun.(Camb.), 52, 2016
4U6L
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BU of 4u6l by Molmil
Crystal structure of DNA/RNA duplex obtained in the presence of [Co(NH3)6]Cl3 and SrCl2
分子名称: COBALT HEXAMMINE(III), DNA (5'-D(*(5CM)P*TP*CP*TP*TP*CP*TP*TP*(5CM))-3'), RNA (5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*G)-3'), ...
著者Kondo, J, Nomura, Y, Kitahara, Y, Obika, S, Torigoe, H.
登録日2014-07-29
公開日2015-08-19
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of a 2',4'-BNA(NC)[N-Me]-modified antisense gapmer in complex with the target RNA.
Chem.Commun.(Camb.), 52, 2016
7MKN
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BU of 7mkn by Molmil
Escherichia coli RNA polymerase and RapA elongation complex
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Qayyum, M.Z, Murakami, K.S.
登録日2021-04-26
公開日2021-06-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli.
J.Biol.Chem., 297, 2021
7KHE
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Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp
分子名称: CHAPSO, DNA (46-MER), DNA (54-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-21
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
7KHB
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Escherichia coli RNA polymerase and rrnBP1 promoter open complex
分子名称: CHAPSO, DNA (60-MER), DNA (64-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-20
公開日2020-10-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
7KHC
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Escherichia coli RNA polymerase and rrnBP1 promoter closed complex
分子名称: CHAPSO, DNA (18 MER), DNA (63-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-20
公開日2020-10-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021

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件を2024-09-04に公開中

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