PDB: 45176 件ウェブページステータス検索Chemie searchBIRD

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4ZX9	X-ray crystal structure of PfA-M17 in complex with hydroxamic acid-based inhibitor 10b 分子名称: CARBONATE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Drinkwater, N, McGowan, S. 登録日 2015-05-20 公開日 2016-03-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions. Eur.J.Med.Chem., 110, 2016
5AJ3	Structure of the small subunit of the mammalian mitoribosome 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MITORIBOSOMAL 12S RRNA, ... 著者 Greber, B.J, Bieri, P, Leibundgut, M, Leitner, A, Aebersold, R, Boehringer, D, Ban, N. 登録日 2015-02-20 公開日 2015-04-22 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome. Science, 348, 2015
4ZSN	70S-wild-type HigB toxin complex bound to a AAA lysine codon 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Schureck, M.A, Dunham, C.M. 登録日 2015-05-13 公開日 2016-09-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Mechanism of endonuclease cleavage by the HigB toxin. Nucleic Acids Res., 44, 2016
5VVB	Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Aminoquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-{[(2-aminoquinolin-7-yl)methyl]amino}ethyl)-2-methylbenzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Li, H, Poulos, T.L. 登録日 2017-05-19 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J. Med. Chem., 60, 2017
5VZ2	Structure of ClpP from Staphylococcus aureus in complex with Acyldepsipeptide 分子名称: ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 著者 Griffith, E.C, Lee, R.E. 登録日 2017-05-26 公開日 2017-06-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Ureadepsipeptides as ClpP Activators. Acs Infect Dis., 2019
5W5O	Identification of potent and selective RIPK2 inhibitors for the treatment of inflammatory diseases. 分子名称: 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine, Receptor-interacting serine/threonine-protein kinase 2 著者 Kreusch, A, Spraggon, G. 登録日 2017-06-15 公開日 2017-10-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett, 8, 2017
5W5R	Agrobacterium tumefaciens ADP-glucose pyrophosphorylase P96A mutant bound to activator pyruvate 分子名称: Glucose-1-phosphate adenylyltransferase, PYRUVIC ACID, SULFATE ION 著者 Mascarenhas, R.N, Hill, B.L, Ballicora, M.A, Liu, D. 登録日 2017-06-15 公開日 2018-11-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.754 Å) 主引用文献 Structural analysis reveals a pyruvate-binding activator site in theAgrobacterium tumefaciensADP-glucose pyrophosphorylase. J. Biol. Chem., 294, 2019
5VOL	Bacint_04212 ferulic acid esterase 分子名称: CALCIUM ION, ISOPROPYL ALCOHOL, Putative esterase 著者 Koropatkin, N.M, Cann, I, Mackie, R.I. 登録日 2017-05-03 公開日 2017-07-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Biochemical and Structural Analyses of Two Cryptic Esterases in Bacteroides intestinalis and their Synergistic Activities with Cognate Xylanases. J. Mol. Biol., 429, 2017
5W6P	Crystal structure of Bacteriophage CBA120 tailspike protein 2 enzymatically active domain (TSP2dN, orf211) 分子名称: 1,2-ETHANEDIOL, POTASSIUM ION, ZINC ION, ... 著者 Plattner, M, Shneider, M.M, Leiman, P.G. 登録日 2017-06-16 公開日 2018-10-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.335 Å) 主引用文献 Structure and Function of the Branched Receptor-Binding Complex of Bacteriophage CBA120. J.Mol.Biol., 431, 2019
5W5T	Agrobacterium tumefaciens ADP-Glucose Pyrophosphorylase bound to activator ethyl pyruvate 分子名称: GLYCEROL, Glucose-1-phosphate adenylyltransferase, SULFATE ION, ... 著者 Mascarenhas, R.N, Hill, B.L, Ballicora, M.A, Liu, D. 登録日 2017-06-15 公開日 2018-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural analysis reveals a pyruvate-binding activator site in theAgrobacterium tumefaciensADP-glucose pyrophosphorylase. J. Biol. Chem., 294, 2019
5VVC	Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Amino-4-methylquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-{[(2-amino-4-methylquinolin-7-yl)methyl]amino}ethyl)-2-methylbenzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Chreifi, G, Li, H, Poulos, T.L. 登録日 2017-05-19 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J. Med. Chem., 60, 2017
5W18	Staphylococcus aureus ClpP in complex with (S)-N-((2R,6S,8aS,14aS,20S,23aS)-2,6-dimethyl-5,8,14,19,23-pentaoxooctadecahydro-1H,5H,14H,19H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1]oxa[4,7,10,13]tetraazacyclohexadecin-20-yl)-3-phenyl-2-(3-phenylureido)propanamide 分子名称: 9V7-PHE-SER-PRO-YCP-ALA-MP8, ATP-dependent Clp protease proteolytic subunit 著者 Lee, R.E, Griffith, E.C. 登録日 2017-06-02 公開日 2017-08-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Ureadepsipeptides as ClpP Activators. Acs Infect Dis., 2019
5W4L	Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with HIV-1 clade A/E gp120, the CD4 mimetic M48U1, and the antibody N5-i5. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody N12-i3 Fab heavy chain, Antibody N12-i3 light chain, ... 著者 Tolbert, W.D, Gohain, N, Pazgier, M. 登録日 2017-06-12 公開日 2017-11-15 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region. Structure, 25, 2017
5W6R	Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with cyclic peptide CP141099 (P6) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-PH8-ORN-LEU-GLU-TYR-PHE-GLU-TRP-LEU-SER-9WV, ... 著者 Wilson, I.A, Kadam, R.U. 登録日 2017-06-16 公開日 2017-10-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.731 Å) 主引用文献 Potent peptidic fusion inhibitors of influenza virus. Science, 358, 2017
5W6J	Agrobacterium tumefaciens ADP-glucose pyrophosphorylase 分子名称: Glucose-1-phosphate adenylyltransferase, SULFATE ION 著者 Mascarenhas, R.N, Hill, B.L, Wu, R, Ballicora, M.A, Liu, D. 登録日 2017-06-16 公開日 2018-11-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural analysis reveals a pyruvate-binding activator site in theAgrobacterium tumefaciensADP-glucose pyrophosphorylase. J. Biol. Chem., 294, 2019
5W4K	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Metelev, M, Osterman, I.A, Ghilarov, D, Khabibullina, N.F, Yakimov, A, Shabalin, K, Utkina, I, Travin, D.Y, Komarova, E.S, Serebryakova, M, Artamonova, T, Khodorkovskii, M, Konevega, A.L, Sergiev, P.V, Severinov, K, Polikanov, Y.S. 登録日 2017-06-12 公開日 2017-08-30 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel. Nat. Chem. Biol., 13, 2017
5WFS	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C4) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-12 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5WNS	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus 分子名称: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 DeMirci, H. 登録日 2017-08-01 公開日 2018-02-21 最終更新日 2020-10-21 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
5WTL	Crystal structure of the periplasmic portion of outer membrane protein A (OmpA) from Capnocytophaga gingivalis 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, OmpA family protein, ... 著者 Dai, S, Tan, K, Ye, S, Zhang, R. 登録日 2016-12-13 公開日 2017-12-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Structure of thrombospondin type 3 repeats in bacterial outer membrane protein A reveals its intra-repeat disulfide bond-dependent calcium-binding capability. Cell Calcium, 66, 2017
5WVI	The resting state of yeast proteasome 分子名称: 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... 著者 Ding, Z, Cong, Y. 登録日 2016-12-25 公開日 2017-03-22 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx Cell Res., 27, 2017
5W7G	An envelope of a filamentous hyperthermophilic virus carries lipids in a horseshoe conformation 分子名称: DNA (253-MER), ORF132, ORF140 著者 Kasson, P, DiMaio, F, Yu, X, Lucas-Staat, S, Krupovic, M, Schouten, S, Prangishvili, D, Egelman, E. 登録日 2017-06-19 公開日 2017-07-19 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Model for a novel membrane envelope in a filamentous hyperthermophilic virus. Elife, 6, 2017
5WC8	Structure of a bacterial polysialyltransferase at 2.75 Angstrom resolution 分子名称: BROMIDE ION, SiaD 著者 Worrall, L.J, Lizak, C, Strynadka, N.C.J. 登録日 2017-06-29 公開日 2017-08-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid. Sci Rep, 7, 2017
5WF0	70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2) 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-11 公開日 2018-05-02 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5WJU	Cryo-EM structure of B. subtilis flagellar filaments A39V, N133H 分子名称: Flagellin 著者 Wang, F, Burrage, A.M, Kearns, D.B, Egelman, E.H. 登録日 2017-07-24 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
5WOB	Crystal Structure Analysis of Fab1-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin 分子名称: IDE-bound Fab heavy chain, IDE-bound Fab light chain, Insulin, ... 著者 McCord, L.A, Liang, W.G, Farcasanu, M, Wang, A.G, Koide, S, Tang, W.J. 登録日 2017-08-01 公開日 2018-04-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.95 Å) 主引用文献 Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018

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