PDB: 1379 件ウェブページステータス検索Chemie searchBIRD

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4DNJ	The crystal structures of 4-methoxybenzoate bound CYP199A2 分子名称: 4-METHOXYBENZOIC ACID, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Zhou, W, Bell, S.G, Yang, W, Tan, A.B.H, Zhou, R, Johnson, E.O.D, Zhang, A, Rao, Z, Wong, L.-L. 登録日 2012-02-08 公開日 2012-08-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The crystal structures of 4-methoxybenzoate bound CYP199A2 and CYP199A4: structural changes on substrate binding and the identification of an anion binding site Dalton Trans, 41, 2012
4C9L	Structure of Cyanide and Camphor bound wild type CYP101D1 分子名称: CAMPHOR, CYANIDE ION, CYTOCHROME P450, ... 著者 Batabyal, D, L Poulos, T. 登録日 2013-10-02 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1. Biochemistry, 52, 2013
4C9M	Structure of substrate free, glycerol bound wild type CYP101D1 分子名称: CYTOCHROME P450, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE 著者 Batabyal, D, L Poulos, T. 登録日 2013-10-02 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1. Biochemistry, 52, 2013
4DUD	cytochrome P450 BM3h-2G9C6 MRI sensor, no ligand 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant 2G9C6 著者 Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. 登録日 2012-02-21 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
4FB2	Crystal Structure of Substrate-Free P450cin 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, P450cin, ... 著者 Madrona, Y, Tripathi, S.M, Li, H, Poulos, T.L. 登録日 2012-05-22 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Crystal structures of substrate-free and nitrosyl cytochrome p450cin: implications for o(2) activation. Biochemistry, 51, 2012
4EGP	The X-ray crystal structure of CYP199A4 in complex with 2-naphthoic acid 分子名称: CHLORIDE ION, Cytochrome P450, GLYCEROL, ... 著者 Zhou, W, Bell, S.G, Yang, W, Zhou, R.M, Tan, A.B.H, Wong, L.-L. 登録日 2012-03-31 公開日 2013-02-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Investigation of the substrate range of CYP199A4: modification of the partition between hydroxylation and desaturation activities by substrate and protein engineering Chemistry, 18, 2012
4EK1	Crystal Structure of Electron-Spin Labeled Cytochrome P450cam 分子名称: CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Lee, Y.-T, Goodin, D.B. 登録日 2012-04-08 公開日 2012-07-25 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Double electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrate. Proc.Natl.Acad.Sci.USA, 109, 2012
4BY0	Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-3,3'- difluoro-(1,1'-biphenyl)-4-carboxamide 分子名称: (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-3,3'-difluoro-(1,1'-biphenyl)-4-carboxamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE 著者 Choi, J.Y, Calvet, C.M, Vierira, D.F, Gunatilleke, S.S, Cameron, M.D, McKerrow, J.H, Podust, L.M, Roush, W.R. 登録日 2013-07-16 公開日 2014-01-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 R-Configuration of 4-Aminopyridyl-Based Inhibitors of Cyp51 Confers Superior Efficacy Against Trypanosoma Cruzi Acs Med.Chem.Lett., 5, 2014
4C0C	Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(2,4-difluorophenyl)piperazin-1-yl)-2-fluorobenzamide. 分子名称: 4-[4-[2,4-bis(fluoranyl)phenyl]piperazin-1-yl]-2-fluoranyl-N-[(2R)-3-(1H-indol-3-yl)-1-oxidanylidene-1-(pyridin-4-ylamino)propan-2-yl]benzamide, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Calvet, C.M, Vieira, D.F, Choi, J.Y, Cameron, M.D, Gut, J, Kellar, D, Siqueira-Neto, J.L, McKerrow, J.H, Roush, W.R, Podust, L.M. 登録日 2013-08-01 公開日 2014-08-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 4-Aminopyridyl-Based Cyp51 Inhibitors as Anti-Trypanosoma Cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency. J.Med.Chem., 57, 2014
4C9O	Structure of Cyanide and Camphor bound D259N mutant of CYP101D1 分子名称: CAMPHOR, CYANIDE ION, CYTOCHROME P450, ... 著者 Batabyal, D, L Poulos, T. 登録日 2013-10-02 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.977 Å) 主引用文献 Crystal Structures and Functional Characterization of Wild-Type Cyp101D1 and its Active Site Mutants. Biochemistry, 52, 2013
4C9N	Structure of camphor and hydroxycamphor bound D259N mutant of CYP101D1 分子名称: 5-EXO-HYDROXYCAMPHOR, CAMPHOR, CYTOCHROME P450, ... 著者 Batabyal, D, L Poulos, T. 登録日 2013-10-02 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1. Biochemistry, 52, 2013
4C9K	Structure of Camphor and Hydroxycamphor bound wild type CYP101D1 分子名称: 5-EXO-HYDROXYCAMPHOR, CAMPHOR, CYTOCHROME P450, ... 著者 Batabyal, D, L Poulos, T. 登録日 2013-10-02 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Crystal Structures and Functional Characterization of Wild-Type Cyp101D1 and its Active Site Mutants. Biochemistry, 52, 2013
4DXY	Crystal structures of CYP101D2 Y96A mutant 分子名称: Cytochrome P450, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE 著者 Zhou, W, Bell, S.G, Yang, W, Dale, A, Wong, L.-L. 登録日 2012-02-28 公開日 2012-08-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Improving the affinity and activity of CYP101D2 for hydrophobic substrates Appl.Microbiol.Biotechnol., 2012
4DTW	cytochrome P450 BM3h-8C8 MRI sensor bound to serotonin 分子名称: Cytochrome P450 BM3 variant 8C8, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. 登録日 2012-02-21 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
4DUA	cytochrome P450 BM3h-9D7 MRI sensor, no ligand 分子名称: PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL, cytochrome P450 BM3 variant 9D7 著者 Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. 登録日 2012-02-21 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
4E2P	Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis 分子名称: Cytochrome P450 107B1 (P450CVIIB1), MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Zhang, H.D, Chen, J, Wang, H, Huang, L, Zhang, H.J. 登録日 2012-03-09 公開日 2013-03-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis To be Published
4FDH	Structure of human aldosterone synthase, CYP11B2, in complex with fadrozole 分子名称: 4-[(5R)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile, Cytochrome P450 11B2, mitochondrial, ... 著者 Strushkevich, N, Shen, L, Tempel, W, Arrowsmith, C, Edwards, A, Usanov, S.A, Park, H.-W. 登録日 2012-05-28 公開日 2013-01-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural insights into aldosterone synthase substrate specificity and targeted inhibition. Mol.Endocrinol., 27, 2013
4FMX	Crystal Structure of Substrate-Bound P450cin 分子名称: 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, GLYCEROL, P450cin, ... 著者 Madrona, Y, Tripathi, S.M, Huiying, L, Poulos, T.L. 登録日 2012-06-18 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.554 Å) 主引用文献 Crystal structures of substrate-free and nitrosyl cytochrome p450cin: implications for o(2) activation. Biochemistry, 51, 2012
4FIA	Crystal Structure of Human CYP46A1 P450 with bicalutamide Bound 分子名称: Cholesterol 24-hydroxylase, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Stout, C.D, Pikuleva, I.A, Mast, N. 登録日 2012-06-08 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Binding of a cyano- and fluoro-containing drug bicalutamide to cytochrome P450 46A1: unusual features and spectral response. J.Biol.Chem., 288, 2013
7V40	Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 分子名称: PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, p450tol monooxygenase 著者 Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2021-08-12 公開日 2022-06-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
7V41	Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with toluene. 分子名称: PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, TOLUENE, ... 著者 Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2021-08-12 公開日 2022-06-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
7V44	Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with meta-chlorotoluene. 分子名称: 1-chloranyl-2-methyl-benzene, GLYCEROL, PHOSPHATE ION, ... 著者 Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2021-08-12 公開日 2022-06-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
7V43	Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with para-chlorotoluene. 分子名称: 1-chloranyl-4-methyl-benzene, GLYCEROL, PHOSPHATE ION, ... 著者 Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2021-08-12 公開日 2022-06-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
7V42	Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with benzyl-alcohol. 分子名称: PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, p450tol monooxygenase, ... 著者 Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2021-08-12 公開日 2022-06-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022
7V45	Crystal structure of Class I P450 monooxygenase (P450tol) from Rhodococcus coprophilus TC-2 in complex with para-bromotoluene. 分子名称: 1-bromanyl-4-methyl-benzene, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Zhang, L.L, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. 登録日 2021-08-12 公開日 2022-06-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Molecular Basis for a Toluene Monooxygenase to Govern Substrate Selectivity Acs Catalysis, 12, 2022

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