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2B7T
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Structure of ADAR2 dsRBM1
分子名称: Double-stranded RNA-specific editase 1
著者Stefl, R, Xu, M, Skrisovska, L, Emeson, R.B, Allain, F.H.-T.
登録日2005-10-05
公開日2006-03-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and specific RNA binding of ADAR2 double-stranded RNA binding motifs.
Structure, 14, 2006
1TNH
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PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS
分子名称: 4-FLUOROBENZYLAMINE, CALCIUM ION, TRYPSIN
著者Kurinov, I, Harrison, R.W.
登録日1994-07-21
公開日1994-11-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Prediction of new serine proteinase inhibitors.
Nat.Struct.Biol., 1, 1994
1LF4
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STRUCTURE OF PLASMEPSIN II
分子名称: Plasmepsin 2
著者Asojo, O.A, Gulnik, S.V, Afonina, E, Yu, B, Ellman, J.A, Haque, T.S, Silva, A.M.
登録日2002-04-10
公開日2002-10-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum.
J.Mol.Biol., 327, 2003
1ZLT
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Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog
分子名称: (4Z)-4-(2-AMINO-5-OXO-3,5-DIHYDRO-4H-IMIDAZOL-4-YLIDENE)-2,3-DICHLORO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8(1H)-ONE, SULFATE ION, Serine/threonine-protein kinase Chk1
著者Lee, C.C, Ng, K, Wan, Y, Gray, N, Spraggon, G.
登録日2005-05-09
公開日2006-06-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog
To be Published
1YXU
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Crystal Structure of Kinase Pim1 in Complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1LFL
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DEOXY HEMOGLOBIN (90% RELATIVE HUMIDITY)
分子名称: Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE
著者Biswal, B.K, Vijayan, M.
登録日2002-04-11
公開日2002-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structures of human oxy- and deoxyhaemoglobin at different levels of humidity: variability in the T state.
Acta Crystallogr.,Sect.D, 58, 2002
2WMW
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Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
分子名称: 1-[(2S)-4-(5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-4-YL)MORPHOLIN-2-YL]METHANAMINE, SERINE/THREONINE-PROTEIN KINASE CHK1
著者Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I.
登録日2009-07-03
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening.
J.Med.Chem., 52, 2009
2B01
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Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Taurochenodeoxycholate
分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
著者Pan, Y.H, Bahnson, B.J, Jain, M.K.
登録日2005-09-12
公開日2006-11-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for bile salt inhibition of pancreatic phospholipase A2.
J.Mol.Biol., 369, 2007
1Z07
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GppNHp-Bound Rab5c G55Q mutant GTPase
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-5C
著者Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G.
登録日2005-03-01
公開日2005-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
Nature, 436, 2005
2BBO
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Human NBD1 with Phe508
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
著者Lewis, H.A, Kearins, M.C, Conners, K, Zhao, X, Lu, F, Sauder, J.M, Emtage, S.
登録日2005-10-17
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
2WMT
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Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
分子名称: 2-(methylsulfanyl)-5-(thiophen-2-ylmethyl)-1H-imidazol-4-ol, SERINE/THREONINE-PROTEIN KINASE CHK1
著者Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I.
登録日2009-07-03
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening.
J.Med.Chem., 52, 2009
2BBX
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NMR solution structure of the TSR domain of malaria TRAP protein
分子名称: Thrombospondin-related anonymous protein
著者Tossavainen, H, Permi, P, Kilpelainen, I.
登録日2005-10-18
公開日2006-08-08
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献The layered fold of the TSR domain of P. falciparum TRAP contains a heparin binding site.
Protein Sci., 15, 2006
2WMV
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Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
分子名称: 1-[(2S)-4-(7H-PURIN-6-YL)MORPHOLIN-2-YL]METHANAMINE, SERINE/THREONINE-PROTEIN KINASE CHK1
著者Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I.
登録日2009-07-03
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.009 Å)
主引用文献Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening.
J.Med.Chem., 52, 2009
1ZNM
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A zinc finger with an artificial beta-turn, original sequence taken from the third zinc finger domain of the human transcriptional repressor protein YY1 (YING and YANG 1, a delta transcription factor), nmr, 34 structures
分子名称: YY1, ZINC ION
著者Viles, J.H, Patel, S.U, Mitchell, J.B.O, Moody, C.M, Justice, D.E, Uppenbrink, J, Doyle, P.M, Harris, C.J, Sadler, P.J, Thornton, J.M.
登録日1997-11-20
公開日1998-04-01
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Design, synthesis and structure of a zinc finger with an artificial beta-turn.
J.Mol.Biol., 279, 1998
1TRY
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STRUCTURE OF INHIBITED TRYPSIN FROM FUSARIUM OXYSPORUM AT 1.55 ANGSTROMS
分子名称: ISOPROPYL ALCOHOL, PHOSPHORYLISOPROPANE, TRYPSIN
著者Rypniewski, W.R, Dambmann, C, Von Der Osten, C, Dauter, M, Wilson, K.S.
登録日1994-03-07
公開日1996-01-01
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of inhibited trypsin from Fusarium oxysporum at 1.55 A.
Acta Crystallogr.,Sect.D, 51, 1995
1KZB
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Complex of MBP-C and trimannosyl core
分子名称: CALCIUM ION, MANNOSE-BINDING PROTEIN C, alpha-D-mannopyranose
著者Ng, K.K, Kolatkar, A.R, Park-Snyder, S, Feinberg, H, Clark, D.A, Drickamer, K, Weis, W.I.
登録日2002-02-06
公開日2002-07-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
J.Biol.Chem., 277, 2002
2WMS
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Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
分子名称: SERINE/THREONINE-PROTEIN KINASE CHK1, [4-amino-2-(tert-butylamino)-1,3-thiazol-5-yl](phenyl)methanone
著者Matthews, T.P, Klair, S, Burns, S, Boxall, K, Cherry, M, Fisher, M, Westwood, I.M, Walton, M.I, McHardy, T, Cheung, K.-M.J, Van Montfort, R, Williams, D, Aherne, G.W, Garrett, M.D, Reader, J, Collins, I.
登録日2009-07-03
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of Inhibitors of Checkpoint Kinase 1 Through Template Screening.
J.Med.Chem., 52, 2009
1TNJ
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PREDICTION OF NOVEL SERINE PROTEASE INHIBITORS
分子名称: 2-PHENYLETHYLAMINE, CALCIUM ION, TRYPSIN
著者Kurinov, I, Harrison, R.W.
登録日1994-07-21
公開日1994-11-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Prediction of new serine proteinase inhibitors.
Nat.Struct.Biol., 1, 1994
1LD6
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STRUCTURE OF BPTI_8A MUTANT
分子名称: PANCREATIC TRYPSIN INHIBITOR
著者Cierpicki, T, Otlewski, J.
登録日2002-04-08
公開日2002-09-11
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability.
J.Mol.Biol., 321, 2002
1YXX
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Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
分子名称: (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
2CQC
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Solution Structure of the RNA recognition motif in Arginine/serine-rich splicing factor 10
分子名称: Arginine/serine-rich splicing factor 10
著者Someya, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-19
公開日2005-11-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of the RNA recognition motif in Arginine/serine-rich splicing factor 10
To be Published
1LG9
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Crystal structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis
分子名称: P450 monooxygenase, PROTOPORPHYRIN IX CONTAINING FE
著者Pylypenko, O, Zerbe, K, Vitali, F, Zhang, W, Vrijbloed, J.W, Robinson, J.A, Schlichting, I.
登録日2002-04-15
公開日2002-12-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis.
J.Biol.Chem., 277, 2002
1L3W
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C-cadherin Ectodomain
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Boggon, T.J, Murray, J, Chappuis-Flament, S, Wong, E, Gumbiner, B.M, Shapiro, L.
登録日2002-03-01
公開日2002-04-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献C-cadherin ectodomain structure and implications for cell adhesion mechanisms
Science, 296, 2002
1LH3
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X-RAY STRUCTURAL INVESTIGATION OF LEGHEMOGLOBIN. VI. STRUCTURE OF ACETATE-FERRILEGHEMOGLOBIN AT A RESOLUTION OF 2.0 ANGSTROMS (RUSSIAN)
分子名称: CYANIDE ION, LEGHEMOGLOBIN (CYANO MET), PROTOPORPHYRIN IX CONTAINING FE
著者Vainshtein, B.K, Harutyunyan, E.H, Kuranova, I.P, Borisov, V.V, Sosfenov, N.I, Pavlovsky, A.G, Grebenko, A.I, Konareva, N.V.
登録日1982-04-23
公開日1983-01-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray Structural Investigation of Leghemoglobin. Vi. Structure of Acetate-Ferrileghemoglobin at a Resolution of 2.0 Angstroms (Russian)
Kristallografiya, 25, 1980
1LHK
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ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS
分子名称: HUMAN LYSOZYME
著者Inaka, K, Matsushima, M, Herning, T, Kuroki, R, Yutani, K, Kikuchi, M.
登録日1992-03-27
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of proline residues in human lysozyme stability: a scanning calorimetric study combined with X-ray structure analysis of proline mutants.
Biochemistry, 31, 1992

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