1T67
 
 | | Crystal Structure of Human HDAC8 complexed with MS-344 | | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, SODIUM ION, ... | | 著者 | Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. | | 登録日 | 2004-05-05 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Structure, 12, 2004
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1R36
 | | NMR-based structure of autoinhibited murine Ets-1 deltaN301 | | 分子名称: | C-ets-1 protein | | 著者 | Lee, G.M, Donaldson, L.W, Pufall, M.A, Kang, H.-S, Pot, I, Graves, B.J, McIntosh, L.P. | | 登録日 | 2003-09-30 | | 公開日 | 2004-11-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structural and Dynamic Basis of Ets-1 DNA Binding Autoinhibition
J.Biol.Chem., 280, 2005
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1SDY
 | | STRUCTURE SOLUTION AND MOLECULAR DYNAMICS REFINEMENT OF THE YEAST CU,ZN ENZYME SUPEROXIDE DISMUTASE | | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Djinovic, K, Gatti, G, Coda, A, Antolini, L, Pelosi, G, Desideri, A, Falconi, M, Marmocchi, F, Rotilio, G, Bolognesi, M. | | 登録日 | 1991-06-14 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase.
Acta Crystallogr.,Sect.B, 47, 1991
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1SHK
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1RG8
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1T69
 | | Crystal Structure of human HDAC8 complexed with SAHA | | 分子名称: | Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ZINC ION | | 著者 | Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. | | 登録日 | 2004-05-05 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Structure, 12, 2004
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1SVP
 | | SINDBIS VIRUS CAPSID PROTEIN | | 分子名称: | SINDBIS VIRUS CAPSID PROTEIN | | 著者 | Lee, S, Rossmann, M.G. | | 登録日 | 1996-03-22 | | 公開日 | 1996-08-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of a protein binding site on the surface of the alphavirus nucleocapsid and its implication in virus assembly.
Structure, 4, 1996
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3F1W
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1U5T
 | | Structure of the ESCRT-II endosomal trafficking complex | | 分子名称: | Defective in vacuolar protein sorting; Vps36p, Hypothetical 23.6 kDa protein in YUH1-URA8 intergenic region, appears to be functionally related to SNF7; Snf8p | | 著者 | Hierro, A, Sun, J, Rusnak, A.S, Kim, J, Prag, G, Emr, S.D, Hurley, J.H. | | 登録日 | 2004-07-28 | | 公開日 | 2004-09-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structure of ESCRT-II endosomal trafficking complex
Nature, 431, 2004
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1RHP
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1RHG
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1SAN
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1U2V
 | | Crystal structure of Arp2/3 complex with bound ADP and calcium | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-Related Protein 2, Actin-Related Protein 3, ... | | 著者 | Nolen, B.J, Littlefield, R.S, Pollard, T.D. | | 登録日 | 2004-07-20 | | 公開日 | 2004-11-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
Proc.Natl.Acad.Sci.Usa, 101, 2004
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1UBB
 | | Crystal structure of rat HO-1 in complex with ferrous heme | | 分子名称: | Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Sakamoto, H, Higashimoto, Y, Noguchi, M, Fukuyama, K. | | 登録日 | 2003-04-03 | | 公開日 | 2003-09-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
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1RML
 | | NMR STUDY OF ACID FIBROBLAST GROWTH FACTOR BOUND TO 1,3,6-NAPHTHALENE TRISULPHONATE, 26 STRUCTURES | | 分子名称: | ACIDIC FIBROBLAST GROWTH FACTOR, NAPHTHALENE TRISULFONATE | | 著者 | Lozano, R.M, Jimenez, M.A, Santoro, J, Rico, M, Gimenez-Gallego, G. | | 登録日 | 1998-05-21 | | 公開日 | 1998-11-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas.
J.Mol.Biol., 281, 1998
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1R78
 | | CDK2 complex with a 4-alkynyl oxindole inhibitor | | 分子名称: | 4-((3R,4S,5R)-4-AMINO-3,5-DIHYDROXY-HEX-1-YNYL)-5-FLUORO-3-[1-(3-METHOXY-1H-PYRROL-2-YL)-METH-(Z)-YLIDENE]-1,3-DIHYDRO-INDOL-2-ONE, Cell division protein kinase 2 | | 著者 | Luk, K.-C, Simcox, M.E, Schutt, A, Rowan, K, Thompson, T, Chen, Y, Kammlott, U, DePinto, W, Dunten, P, Dermatakis, A. | | 登録日 | 2003-10-20 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A new series of potent oxindole inhibitors of CDK2
Bioorg.Med.Chem.Lett., 14, 2004
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1T6R
 | | Solution structure of TM1442, a putative anti sigma factor antagonist in phosphorylated state | | 分子名称: | Putative anti-sigma factor antagonist TM1442 | | 著者 | Etezady-Esfarjani, T, Placzek, W, Herrmann, T, Lesley, S.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | 登録日 | 2004-05-07 | | 公開日 | 2005-05-24 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the putative anti-sigma-factor antagonist TM1442 from Thermotoga maritima in the free and phosphorylated states.
Magn.Reson.Chem., 44 Spec No, 2006
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1Y0V
 | | Crystal structure of anthrax edema factor (EF) in complex with calmodulin and pyrophosphate | | 分子名称: | CALCIUM ION, Calmodulin, Calmodulin-sensitive adenylate cyclase, ... | | 著者 | Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.-J. | | 登録日 | 2004-11-16 | | 公開日 | 2005-05-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor
Embo J., 24, 2005
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1TYQ
 | | Crystal structure of Arp2/3 complex with bound ATP and calcium | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related Protein 2, Actin-related protein 3, ... | | 著者 | Nolen, B.J, Littlefield, R.S, Pollard, T.D. | | 登録日 | 2004-07-08 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
Proc.Natl.Acad.Sci.Usa, 101, 2004
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6GVT
 | | Hybrid structure of the pRN1 helix bundle domain in complex with DNA and 2 ATP molecules | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*CP*A)-3'), MAGNESIUM ION, ... | | 著者 | Boudet, J, Wiegand, T, Meier, B.H, Lipps, G, Allain, F.H.-T. | | 登録日 | 2018-06-21 | | 公開日 | 2018-12-26 | | 最終更新日 | 2019-08-21 | | 実験手法 | SOLID-STATE NMR, SOLUTION NMR | | 主引用文献 | A Small Helical Bundle Prepares Primer Synthesis by Binding Two Nucleotides that Enhance Sequence-Specific Recognition of the DNA Template.
Cell, 176, 2019
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1RZY
 | | Crystal structure of rabbit Hint complexed with N-ethylsulfamoyladenosine | | 分子名称: | 5'-O-(N-ETHYL-SULFAMOYL)ADENOSINE, Histidine triad nucleotide-binding protein 1 | | 著者 | Krakowiak, A.K, Pace, H.C, Blackburn, G.M, Adams, M, Mekhalfia, A, Kaczmarek, R, Baraniak, J, Stec, W.J, Brenner, C. | | 登録日 | 2003-12-29 | | 公開日 | 2004-03-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors
J.Biol.Chem., 279, 2004
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1ULX
 | | Partially photolyzed structure of CO-bound heme-heme oxygenase complex | | 分子名称: | CARBON MONOXIDE, Heme oxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sugishima, M, Sakamoto, H, Noguchi, M, Fukuyama, K. | | 登録日 | 2003-09-16 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | CO-trapping site in heme oxygenase revealed by photolysis of its co-bound heme complex: mechanism of escaping from product inhibition
J.Mol.Biol., 341, 2004
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3WWQ
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1URC
 | | Cyclin A binding groove inhibitor Ace-Arg-Lys-Leu-Phe-Gly | | 分子名称: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, PEPTIDE INHIBITOR | | 著者 | Kontopidis, G, Andrews, M, McInnes, C, Cowan, A, Powers, H, Innes, L, Plater, A, Griffiths, G, Paterson, D, Zheleva, D, Lane, D, Green, S, Walkinshaw, M, Fischer, P. | | 登録日 | 2003-10-28 | | 公開日 | 2003-10-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes.
Org. Biomol. Chem., 2, 2004
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1T64
 | | Crystal Structure of human HDAC8 complexed with Trichostatin A | | 分子名称: | CALCIUM ION, Histone deacetylase 8, SODIUM ION, ... | | 著者 | Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. | | 登録日 | 2004-05-05 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Structure, 12, 2004
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