5Z18
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5Z1B
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3E1F
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3DYP
| E. coli (lacZ) beta-galactosidase (H418N) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Juers, D.H, Huber, R.E, Matthews, B.W. | 登録日 | 2008-07-28 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli). Protein Sci., 18, 2009
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6B6L
| The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, Glycosyl hydrolase family 2, ... | 著者 | Tan, K, Joachimiak, G, Nocek, B, Enddres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-10-02 | 公開日 | 2017-10-11 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 To Be Published
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6BJQ
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6BJW
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3FN9
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6TSK
| Beta-galactosidase in complex with L-ribose | 分子名称: | Beta-galactosidase, MAGNESIUM ION, beta-L-ribopyranose | 著者 | Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. | 登録日 | 2019-12-20 | 公開日 | 2020-01-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
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6TSH
| Beta-galactosidase in complex with deoxygalacto-nojirimycin | 分子名称: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-galactosidase, MAGNESIUM ION | 著者 | Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. | 登録日 | 2019-12-20 | 公開日 | 2020-01-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
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6U7J
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3I3D
| E. COLI (lacZ) BETA-GALACTOSIDASE (M542A) IN COMPLEX WITH IPTG | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E. | 登録日 | 2009-06-30 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem.Cell Biol., 88, 2010
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6QUB
| Truncated beta-galactosidase III from Bifidobacterium bifidum in complex with galactose | 分子名称: | Beta-galactosidase, CALCIUM ION, beta-D-galactopyranose | 著者 | Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. | 登録日 | 2019-02-27 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Truncated beta-galactosidase III from Bifidobacterium bifidum To Be Published
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6QUC
| Truncated beta-galactosidase III from Bifidobacterium bifidum | 分子名称: | Beta-galactosidase, CALCIUM ION, IMIDAZOLE | 著者 | Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. | 登録日 | 2019-02-27 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Truncated beta-galactosidase III from Bifidobacterium bifidum To Be Published
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6QUD
| 2-deoxy-galactose reaction intermediate of a Truncated beta-galactosidase III from Bifidobacterium bifidum | 分子名称: | 2-deoxy-alpha-D-galactopyranose, Beta-galactosidase, CALCIUM ION | 著者 | Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. | 登録日 | 2019-02-27 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Truncated beta-galactosidase III from Bifidobacterium bifidum To Be Published
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6U7I
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3HN3
| Human beta-glucuronidase at 1.7 A resolution | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Klei, H.E, Ghosh, K, Anumula, R. | 登録日 | 2009-05-29 | 公開日 | 2009-12-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Human beta-glucuronidasel at 1.7 A resolution To be Published
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3I3B
| E.coli (lacz) Beta-Galactosidase (M542A) in Complex with D-Galactopyranosyl-1-on | 分子名称: | Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ... | 著者 | Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E. | 登録日 | 2009-06-30 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem.Cell Biol., 88, 2010
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6SD0
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6TTE
| Beta-galactosidase in complex with PETG | 分子名称: | 2-phenylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, MAGNESIUM ION | 著者 | Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. | 登録日 | 2019-12-27 | 公開日 | 2020-01-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
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3I3E
| E. COLI (lacZ) BETA-GALACTOSIDASE (M542A) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Dugdale, M.L, Dymianiw, D, Minhas, B, Huber, R.E. | 登録日 | 2009-06-30 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem.Cell Biol., 88, 2010
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6S6Z
| Structure of beta-Galactosidase from Thermotoga maritima | 分子名称: | Beta-galactosidase, MAGNESIUM ION | 著者 | Miguez-Amil, S, Jimenez-Ortega, E, Ramirez Escudero, M, Sanz-Aparicio, J, Fernandez-Leiro, R. | 登録日 | 2019-07-04 | 公開日 | 2020-03-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | The cryo-EM Structure ofThermotoga maritimabeta-Galactosidase: Quaternary Structure Guides Protein Engineering. Acs Chem.Biol., 15, 2020
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3IAP
| E. coli (lacZ) beta-galactosidase (E416Q) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E. | 登録日 | 2009-07-14 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry Protein J., 29, 2010
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3GM8
| Crystal structure of a beta-glycosidase from Bacteroides vulgatus | 分子名称: | GLYCEROL, Glycoside hydrolase family 2, candidate beta-glycosidase | 著者 | Bonanno, J.B, Rutter, M, Bain, K.T, Iizuka, M, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-03-13 | 公開日 | 2009-03-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of a beta-glycosidase from Bacteroides vulgatus To be Published
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3IAQ
| E. coli (lacz) beta-galactosidase (E416V) | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | 著者 | Lo, S, Dugdale, M.L, Jeerh, N, Ku, T, Roth, N.J, Huber, R.E. | 登録日 | 2009-07-14 | 公開日 | 2009-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Studies of Glu-416 variants of beta-galactosidase (E. coli) show that the active site Mg(2+) is not important for structure and indicate that the main role of Mg (2+) is to mediate optimization of active site chemistry Protein J., 29, 2010
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