1MFU
| Probing the role of a mobile loop in human salivary amylase: Structural studies on the loop-deleted mutant | 分子名称: | 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ... | 著者 | Ramasubbu, N, Ragunath, C, Mishra, P.J. | 登録日 | 2002-08-13 | 公開日 | 2002-11-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Probing the role of a mobile loop in substrate binding and enzyme activity of
human salivary amylase. J.Mol.Biol., 325, 2003
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1WO2
| Crystal structure of the pig pancreatic alpha-amylase complexed with malto-oligosaacharides under the effect of the chloride ion | 分子名称: | 1,2-ETHANEDIOL, Alpha-amylase, pancreatic, ... | 著者 | Qian, M, Payan, F, Nahoum, V. | 登録日 | 2004-08-11 | 公開日 | 2005-03-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Molecular Basis of the Effects of Chloride Ion on the Acid-Base Catalyst in the Mechanism of Pancreatic alpha-Amylase Biochemistry, 44, 2005
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1UA3
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1JFH
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1XH1
| Structure of the N298S variant of human pancreatic alpha-amylase complexed with chloride | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, pancreatic, ... | 著者 | Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D. | 登録日 | 2004-09-17 | 公開日 | 2005-05-24 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase PROTEIN SCI., 14, 2005
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8CQF
| Crystal Structure of a Chimeric Alpha-Amylase from Pseudoalteromonas Haloplanktis Complexed with Rearranged Acarbose | 分子名称: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-1,5-anhydro-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | 著者 | Skagseth, S, Griese, J.J, Lund, B.A, van der Ent, F, Aqvist, J. | 登録日 | 2023-03-06 | 公開日 | 2023-06-21 | 最終更新日 | 2023-07-12 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Computational design of the temperature optimum of an enzyme reaction. Sci Adv, 9, 2023
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1Q4N
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7P45
| Structure of CgGBE in P212121 space group | 分子名称: | 1,2-ETHANEDIOL, 1,4-alpha-glucan-branching enzyme | 著者 | Ballut, L, Conchou, L, Violot, S, Galisson, F, Aghajari, N. | 登録日 | 2021-07-09 | 公開日 | 2022-07-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The Candida glabrata glycogen branching enzyme structure reveals unique features of branching enzymes of the Saccharomycetaceae phylum. Glycobiology, 32, 2022
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1CXK
| COMPLEX BETWEEN A MALTONONAOSE SUBSTRATE AND BACILLUS CIRCULANS STRAIN 251 CGTASE E257Q/D229N | 分子名称: | CALCIUM ION, PROTEIN (CYCLODEXTRIN-GLYCOSYLTRANSFERASE), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | 著者 | Uitdehaag, J.C.M, Kalk, K.H, Dijkstra, B.W. | 登録日 | 1999-02-24 | 公開日 | 1999-05-03 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family. Nat.Struct.Biol., 6, 1999
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1NM9
| Crystal structure of recombinant human salivary amylase mutant W58A | 分子名称: | 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, Alpha-amylase, ... | 著者 | Ramasubbu, N, Ragunath, C, Mishra, P.J, Thomas, L.M. | 登録日 | 2003-01-09 | 公開日 | 2004-01-20 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Human salivary alpha-amylase Trp58 situated at subsite -2 is critical for enzyme activity. Eur.J.Biochem., 271, 2004
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1CXF
| COMPLEX OF A (D229N/E257Q) DOUBLE MUTANT CGTASE FROM BACILLUS CIRCULANS STRAIN 251 WITH MALTOTETRAOSE AT 120 K AND PH 9.1 OBTAINED AFTER SOAKING THE CRYSTAL WITH ALPHA-CYCLODEXTRIN | 分子名称: | CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), ... | 著者 | Knegtel, R.M.A, Strokopytov, B.V, Dijkstra, B.W. | 登録日 | 1995-07-28 | 公開日 | 1995-12-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products. J.Biol.Chem., 270, 1995
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1KGW
| THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337Q VARIANT OF HUMAN PANCREATIC ALPHA-MYLASE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-28 | 公開日 | 2002-01-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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1OT2
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1KB3
| Three Dimensional Structure Analysis of the R195A Variant of Human Pancreatic Alpha Amylase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ... | 著者 | Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2001-11-05 | 公開日 | 2002-05-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase. Biochemistry, 41, 2002
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1V3L
| Crystal structure of F283L mutant cyclodextrin glycosyltransferase complexed with a pseudo-tetraose derived from acarbose | 分子名称: | 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-beta-D-galactopyranose, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, ... | 著者 | Kanai, R, Haga, K, Akiba, T, Yamane, K, Harata, K. | 登録日 | 2003-11-03 | 公開日 | 2004-08-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site PROTEIN SCI., 13, 2004
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1L0P
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3BAJ
| Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ... | 著者 | Fredriksen, J.R, Maurus, R, Brayer, G.D. | 登録日 | 2007-11-07 | 公開日 | 2008-03-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity Biochemistry, 47, 2008
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1CXE
| COMPLEX OF CGTASE WITH MALTOTETRAOSE AT ROOM TEMPERATURE AND PH 9.1 BASED ON DIFFRACTION DATA OF A CRYSTAL SOAKED WITH ALPHA-CYCLODEXTRIN | 分子名称: | CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | 著者 | Knegtel, R.M.A, Strokopytov, B.V, Dijkstra, B.W. | 登録日 | 1995-07-28 | 公開日 | 1995-12-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products. J.Biol.Chem., 270, 1995
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3L2L
| X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Limit Dextrin and Oligosaccharide | 分子名称: | CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ... | 著者 | Larson, S.B, Day, J.S, McPherson, A. | 登録日 | 2009-12-15 | 公開日 | 2010-04-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin. Biochemistry, 49, 2010
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1PIG
| PIG PANCREATIC ALPHA-AMYLASE COMPLEXED WITH THE OLIGOSACCHARIDE V-1532 | 分子名称: | 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ... | 著者 | Machius, M, Vertesy, L, Huber, R, Wiegand, G. | 登録日 | 1996-06-15 | 公開日 | 1996-12-07 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Carbohydrate and protein-based inhibitors of porcine pancreatic alpha-amylase: structure analysis and comparison of their binding characteristics. J.Mol.Biol., 260, 1996
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1XD1
| Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED HEXASACCHARIDE, Alpha-amylase, ... | 著者 | Li, C, Begum, A, Numao, S, Park, K.H, Withers, S.G, Brayer, G.D. | 登録日 | 2004-09-03 | 公開日 | 2004-12-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts Biochemistry, 44, 2005
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1CXI
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1UKT
| Crystal structure of Y100L mutant cyclodextrin glucanotransferase compexed with an acarbose | 分子名称: | 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-galactopyranose, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, CALCIUM ION, ... | 著者 | Haga, K, Kanai, R, Sakamoto, O, Harata, K, Yamane, K. | 登録日 | 2003-09-01 | 公開日 | 2004-02-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Effects of Essential Carbohydrate/Aromatic Stacking Interaction with Tyr100 and Phe259 on Substrate Binding of Cyclodextrin Glycosyltransferase from Alkalophilic Bacillus sp. 1011 J.Biochem.(Tokyo), 134, 2003
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1PPI
| THE ACTIVE CENTER OF A MAMMALIAN ALPHA-AMYLASE. THE STRUCTURE OF THE COMPLEX OF A PANCREATIC ALPHA-AMYLASE WITH A CARBOHYDRATE INHIBITOR REFINED TO 2.2 ANGSTROMS RESOLUTION | 分子名称: | 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose, ALPHA-AMYLASE, CALCIUM ION, ... | 著者 | Qian, M, Haser, R, Payan, F. | 登録日 | 1994-02-22 | 公開日 | 1995-05-24 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The active center of a mammalian alpha-amylase. Structure of the complex of a pancreatic alpha-amylase with a carbohydrate inhibitor refined to 2.2-A resolution. Biochemistry, 33, 1994
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1XH2
| Structure of the N298S variant of human pancreatic alpha-amylase complexed with chloride and acarbose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, Alpha-amylase, ... | 著者 | Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D. | 登録日 | 2004-09-17 | 公開日 | 2005-05-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase PROTEIN SCI., 14, 2005
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