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1MFU
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Probing the role of a mobile loop in human salivary amylase: Structural studies on the loop-deleted mutant
分子名称: 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ...
著者Ramasubbu, N, Ragunath, C, Mishra, P.J.
登録日2002-08-13
公開日2002-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the role of a mobile loop in substrate binding and enzyme activity of human salivary amylase.
J.Mol.Biol., 325, 2003
1WO2
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Crystal structure of the pig pancreatic alpha-amylase complexed with malto-oligosaacharides under the effect of the chloride ion
分子名称: 1,2-ETHANEDIOL, Alpha-amylase, pancreatic, ...
著者Qian, M, Payan, F, Nahoum, V.
登録日2004-08-11
公開日2005-03-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Molecular Basis of the Effects of Chloride Ion on the Acid-Base Catalyst in the Mechanism of Pancreatic alpha-Amylase
Biochemistry, 44, 2005
1UA3
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Crystal structure of the pig pancreatic a-amylase complexed with malto-oligosaccharides
分子名称: 1,2-ETHANEDIOL, Alpha-amylase, pancreatic, ...
著者Payan, F, Qian, M.
登録日2003-02-27
公開日2003-10-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structure of the Pig Pancreatic alpha-Amylase Complexed with Malto-Oligosaccharides
J.PROTEIN CHEM., 22, 2003
1JFH
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STRUCTURE OF A PANCREATIC ALPHA-AMYLASE BOUND TO A SUBSTRATE ANALOGUE AT 2.03 ANGSTROM RESOLUTION
分子名称: 4-S-methyl-4-thio-alpha-D-glucopyranose-(1-4)-methyl 4-thio-alpha-D-glucopyranoside, ALPHA-AMYLASE, CALCIUM ION, ...
著者Qian, M, Payan, F.
登録日1997-09-19
公開日1998-12-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structure of a pancreatic alpha-amylase bound to a substrate analogue at 2.03 A resolution.
Protein Sci., 6, 1997
1XH1
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Structure of the N298S variant of human pancreatic alpha-amylase complexed with chloride
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, pancreatic, ...
著者Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D.
登録日2004-09-17
公開日2005-05-24
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase
PROTEIN SCI., 14, 2005
8CQF
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Crystal Structure of a Chimeric Alpha-Amylase from Pseudoalteromonas Haloplanktis Complexed with Rearranged Acarbose
分子名称: 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-1,5-anhydro-D-glucitol, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Skagseth, S, Griese, J.J, Lund, B.A, van der Ent, F, Aqvist, J.
登録日2023-03-06
公開日2023-06-21
最終更新日2023-07-12
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Computational design of the temperature optimum of an enzyme reaction.
Sci Adv, 9, 2023
1Q4N
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Structural studies of Phe256Trp of human salivary alpha-amylase: implications for the role of a conserved water molecule and its associated chain in enzyme activity
分子名称: Alpha-amylase, salivary, CALCIUM ION, ...
著者Ramasubbu, N.
登録日2003-08-04
公開日2004-03-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural studies of a Phe256Trp mutant of human salivary alpha-amylase: implications for the role of a conserved water molecule in enzyme activity
Arch.Biochem.Biophys., 421, 2004
7P45
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Structure of CgGBE in P212121 space group
分子名称: 1,2-ETHANEDIOL, 1,4-alpha-glucan-branching enzyme
著者Ballut, L, Conchou, L, Violot, S, Galisson, F, Aghajari, N.
登録日2021-07-09
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The Candida glabrata glycogen branching enzyme structure reveals unique features of branching enzymes of the Saccharomycetaceae phylum.
Glycobiology, 32, 2022
1CXK
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COMPLEX BETWEEN A MALTONONAOSE SUBSTRATE AND BACILLUS CIRCULANS STRAIN 251 CGTASE E257Q/D229N
分子名称: CALCIUM ION, PROTEIN (CYCLODEXTRIN-GLYCOSYLTRANSFERASE), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Uitdehaag, J.C.M, Kalk, K.H, Dijkstra, B.W.
登録日1999-02-24
公開日1999-05-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family.
Nat.Struct.Biol., 6, 1999
1NM9
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Crystal structure of recombinant human salivary amylase mutant W58A
分子名称: 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, Alpha-amylase, ...
著者Ramasubbu, N, Ragunath, C, Mishra, P.J, Thomas, L.M.
登録日2003-01-09
公開日2004-01-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human salivary alpha-amylase Trp58 situated at subsite -2 is critical for enzyme activity.
Eur.J.Biochem., 271, 2004
1CXF
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BU of 1cxf by Molmil
COMPLEX OF A (D229N/E257Q) DOUBLE MUTANT CGTASE FROM BACILLUS CIRCULANS STRAIN 251 WITH MALTOTETRAOSE AT 120 K AND PH 9.1 OBTAINED AFTER SOAKING THE CRYSTAL WITH ALPHA-CYCLODEXTRIN
分子名称: CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, Cyclohexakis-(1-4)-(alpha-D-glucopyranose), ...
著者Knegtel, R.M.A, Strokopytov, B.V, Dijkstra, B.W.
登録日1995-07-28
公開日1995-12-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products.
J.Biol.Chem., 270, 1995
1KGW
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THREE DIMENSIONAL STRUCTURE ANALYSIS OF THE R337Q VARIANT OF HUMAN PANCREATIC ALPHA-MYLASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ...
著者Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日2001-11-28
公開日2002-01-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
1OT2
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Bacillus circulans strain 251 Cyclodextrin glycosyl transferase mutant D135N
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETIC ACID, ...
著者Rozeboom, H.J, Dijkstra, B.W.
登録日2003-03-21
公開日2003-06-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The fully conserved Asp residue in Conserved sequence region I of the alpha-amylase Family is crucial for the Catalytic Site Architecture and Activity
Febs Lett., 541, 2003
1KB3
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Three Dimensional Structure Analysis of the R195A Variant of Human Pancreatic Alpha Amylase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-AMYLASE, PANCREATIC, ...
著者Numao, S, Maurus, R, Sidhu, G, Wang, Y, Overall, C.M, Brayer, G.D, Withers, S.G.
登録日2001-11-05
公開日2002-05-01
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase.
Biochemistry, 41, 2002
1V3L
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Crystal structure of F283L mutant cyclodextrin glycosyltransferase complexed with a pseudo-tetraose derived from acarbose
分子名称: 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-beta-D-galactopyranose, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, ...
著者Kanai, R, Haga, K, Akiba, T, Yamane, K, Harata, K.
登録日2003-11-03
公開日2004-08-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site
PROTEIN SCI., 13, 2004
1L0P
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BU of 1l0p by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX BETWEEN PSYCHROPHILIC ALPHA AMYLASE FROM PSEUDOALTEROMONAS HALOPLANCTIS AND NITRATE
分子名称: ALPHA-AMYLASE, CALCIUM ION, NITRATE ION
著者Aghajari, N, Haser, R.
登録日2002-02-12
公開日2002-06-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of alpha-amylase activation by chloride.
Protein Sci., 11, 2002
3BAJ
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Human Pancreatic Alpha-Amylase in Complex with Nitrate and Acarbose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, CALCIUM ION, ...
著者Fredriksen, J.R, Maurus, R, Brayer, G.D.
登録日2007-11-07
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity
Biochemistry, 47, 2008
1CXE
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BU of 1cxe by Molmil
COMPLEX OF CGTASE WITH MALTOTETRAOSE AT ROOM TEMPERATURE AND PH 9.1 BASED ON DIFFRACTION DATA OF A CRYSTAL SOAKED WITH ALPHA-CYCLODEXTRIN
分子名称: CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者Knegtel, R.M.A, Strokopytov, B.V, Dijkstra, B.W.
登録日1995-07-28
公開日1995-12-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products.
J.Biol.Chem., 270, 1995
3L2L
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X-ray Crystallographic Analysis of Pig Pancreatic Alpha-Amylase with Limit Dextrin and Oligosaccharide
分子名称: CALCIUM ION, CHLORIDE ION, Pancreatic alpha-amylase, ...
著者Larson, S.B, Day, J.S, McPherson, A.
登録日2009-12-15
公開日2010-04-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献X-ray crystallographic analyses of pig pancreatic alpha-amylase with limit dextrin, oligosaccharide, and alpha-cyclodextrin.
Biochemistry, 49, 2010
1PIG
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BU of 1pig by Molmil
PIG PANCREATIC ALPHA-AMYLASE COMPLEXED WITH THE OLIGOSACCHARIDE V-1532
分子名称: 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-amino-4,6-dideoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, 5-HYDROXYMETHYL-CHONDURITOL, ...
著者Machius, M, Vertesy, L, Huber, R, Wiegand, G.
登録日1996-06-15
公開日1996-12-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Carbohydrate and protein-based inhibitors of porcine pancreatic alpha-amylase: structure analysis and comparison of their binding characteristics.
J.Mol.Biol., 260, 1996
1XD1
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Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED HEXASACCHARIDE, Alpha-amylase, ...
著者Li, C, Begum, A, Numao, S, Park, K.H, Withers, S.G, Brayer, G.D.
登録日2004-09-03
公開日2004-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts
Biochemistry, 44, 2005
1CXI
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WILD-TYPE CGTASE FROM BACILLUS CIRCULANS STRAIN 251 AT 120 K AND PH 7.55
分子名称: CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Knegtel, R.M.A, Strokopytov, B.V, Dijkstra, B.W.
登録日1995-07-31
公開日1995-12-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products.
J.Biol.Chem., 270, 1995
1UKT
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Crystal structure of Y100L mutant cyclodextrin glucanotransferase compexed with an acarbose
分子名称: 4,6-dideoxy-alpha-D-xylo-hexopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-galactopyranose, 6-AMINO-4-HYDROXYMETHYL-CYCLOHEX-4-ENE-1,2,3-TRIOL, CALCIUM ION, ...
著者Haga, K, Kanai, R, Sakamoto, O, Harata, K, Yamane, K.
登録日2003-09-01
公開日2004-02-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Effects of Essential Carbohydrate/Aromatic Stacking Interaction with Tyr100 and Phe259 on Substrate Binding of Cyclodextrin Glycosyltransferase from Alkalophilic Bacillus sp. 1011
J.Biochem.(Tokyo), 134, 2003
1PPI
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THE ACTIVE CENTER OF A MAMMALIAN ALPHA-AMYLASE. THE STRUCTURE OF THE COMPLEX OF A PANCREATIC ALPHA-AMYLASE WITH A CARBOHYDRATE INHIBITOR REFINED TO 2.2 ANGSTROMS RESOLUTION
分子名称: 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose, ALPHA-AMYLASE, CALCIUM ION, ...
著者Qian, M, Haser, R, Payan, F.
登録日1994-02-22
公開日1995-05-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The active center of a mammalian alpha-amylase. Structure of the complex of a pancreatic alpha-amylase with a carbohydrate inhibitor refined to 2.2-A resolution.
Biochemistry, 33, 1994
1XH2
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Structure of the N298S variant of human pancreatic alpha-amylase complexed with chloride and acarbose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED PENTASACCHARIDE, Alpha-amylase, ...
著者Maurus, R, Begum, A, Kuo, H.H, Racaza, A, Numao, S, Overall, C.M, Withers, S.G, Brayer, G.D.
登録日2004-09-17
公開日2005-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase
PROTEIN SCI., 14, 2005

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