7AK6
 
 | | Cryo-EM structure of ND6-P25L mutant respiratory complex I from Mus musculus at 3.8 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Structural basis for a complex I mutation that blocks pathological ROS production.
Nat Commun, 12, 2021
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7AK5
 | | Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Yin, Z, Bridges, H.R, Grba, D, Hirst, J. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-03 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Structural basis for a complex I mutation that blocks pathological ROS production.
Nat Commun, 12, 2021
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7B0N
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8BEF
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | | 著者 | Klusch, N, Kuehlbrandt, W. | | 登録日 | 2022-10-21 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (2.13 Å) | | 主引用文献 | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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8BA0
 | | Drosophila melanogaster complex I in the Twisted state (Dm2) | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | | 著者 | Agip, A.N.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | | 登録日 | 2022-10-10 | | 公開日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
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8BPX
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete composition) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | | 著者 | Klusch, N, Kuehlbrandt, W. | | 登録日 | 2022-11-18 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (2.09 Å) | | 主引用文献 | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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8B9Z
 | | Drosophila melanogaster complex I in the Active state (Dm1) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | | 登録日 | 2022-10-10 | | 公開日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
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7AQQ
 | | Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane core) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | | 著者 | Klusch, N, Kuehlbrandt, W, Yildiz, O. | | 登録日 | 2020-10-22 | | 公開日 | 2021-12-08 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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7A24
 | | Assembly intermediate of the plant mitochondrial complex I | | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 13kDa, 15kDa, ... | | 著者 | Soufari, H, Waltz, F, Hashem, Y. | | 登録日 | 2020-08-16 | | 公開日 | 2020-10-28 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Specific features and assembly of the plant mitochondrial complex I revealed by cryo-EM.
Nat Commun, 11, 2020
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7AR8
 | | Cryo-EM structure of Arabidopsis thaliana complex-I (closed conformation) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | | 著者 | Klusch, N, Kuelbrandt, W, Yildiz, O. | | 登録日 | 2020-10-23 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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7ARB
 | | Cryo-EM structure of Arabidopsis thaliana Complex-I (complete composition) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | | 著者 | Klusch, N, Kuelbrandt, W, Yildiz, O. | | 登録日 | 2020-10-23 | | 公開日 | 2021-12-15 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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8BQ6
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 2 composition) | | 分子名称: | 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ... | | 著者 | Klusch, N, Kuehlbrandt, W. | | 登録日 | 2022-11-18 | | 公開日 | 2023-05-10 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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7AR7
 | | Cryo-EM structure of Arabidopsis thaliana complex-I (open conformation) | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ... | | 著者 | Klusch, N, Kuelbrandt, W. | | 登録日 | 2020-10-23 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
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8BQ5
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 1 composition) | | 分子名称: | 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ... | | 著者 | Klusch, N, Kuehlbrandt, W. | | 登録日 | 2022-11-18 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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8B6F
 | | Cryo-EM structure of NADH:ubiquinone oxidoreductase (complex-I) from respiratory supercomplex of Tetrahymena thermophila | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... | | 著者 | Muhleip, A, Kock Flygaard, R, Amunts, A. | | 登録日 | 2022-09-27 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Nature, 615, 2023
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6ZTQ
 | | Cryo-EM structure of respiratory complex I from Mus musculus inhibited by piericidin A at 3.0 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J. | | 登録日 | 2020-07-20 | | 公開日 | 2020-10-21 | | 最終更新日 | 2020-10-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
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6ZR2
 | | Cryo-EM structure of respiratory complex I in the active state from Mus musculus at 3.1 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Bridges, H.R, Blaza, J.N, Agip, A.N.A, Hirst, J. | | 登録日 | 2020-07-10 | | 公開日 | 2020-10-21 | | 最終更新日 | 2020-10-28 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of inhibitor-bound mammalian complex I.
Nat Commun, 11, 2020
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8BQS
 | | Cryo-EM structure of the I-II-III2-IV2 respiratory supercomplex from Tetrahymena thermophila | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... | | 著者 | Muhleip, A, Kock Flygaard, R, Baradaran, R, Amunts, A. | | 登録日 | 2022-11-21 | | 公開日 | 2023-08-23 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of mitochondrial membrane bending by I-II-III2-IV2 supercomplex
To Be Published
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7ZKP
 | | Late assembly intermediate of the proximal proton pumping module of complex I with assembly factors NDUFAF1 and CIA84 | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, ... | | 著者 | Schiller, J, Laube, E, Vonck, J, Zickermann, V. | | 登録日 | 2022-04-13 | | 公開日 | 2022-11-23 | | 最終更新日 | 2022-11-30 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling.
Sci Adv, 8, 2022
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7ZMH
 | | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Laube, E, Kuehlbrandt, W. | | 登録日 | 2022-04-19 | | 公開日 | 2022-11-30 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.47 Å) | | 主引用文献 | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
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7ZM8
 | | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) - membrane arm | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Laube, E, Kuehlbrandt, W. | | 登録日 | 2022-04-19 | | 公開日 | 2022-11-30 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
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7ZM7
 | | CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Laube, E, Kuehlbrandt, W. | | 登録日 | 2022-04-19 | | 公開日 | 2022-11-30 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | | 主引用文献 | Conformational changes in mitochondrial complex I of the thermophilic eukaryote Chaetomium thermophilum.
Sci Adv, 8, 2022
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7TGH
 | | Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2 iron, ... | | 著者 | Zhou, L, Maldonado, M, Padavannil, A, Guo, F, Letts, J.A. | | 登録日 | 2022-01-07 | | 公開日 | 2022-04-06 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
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7V33
 | | Active state complex I from rotenone-NADH dataset | | 分子名称: | (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | | 著者 | Gu, J.K, Yang, M.J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
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7V32
 | | Deactive state complex I from rotenone dataset | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Gu, J.K, Yang, M.J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
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