4UIZ
 
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4-dimethoxyphenyl)-2-(4-methanesulfonylpiperazine-1-carbonyl)-5-methyl-4H,5H-thieno-3,2-c- pyridin-4-one | | 分子名称: | 1,2-ETHANEDIOL, 7-(3,4-dimethoxyphenyl)-5-methyl-2-(4-methylsulfonylpiperazin-1-yl)carbonyl-thieno[3,2-c]pyridin-4-one, BROMODOMAIN-CONTAINING PROTEIN 4 | | 著者 | Chung, C, Theodoulou, N.T, Bamborough, P, Humphreys, P.G. | | 登録日 | 2015-04-03 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | The Discovery of I-Brd9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
J.Med.Chem., 59, 2016
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4V3D
 | | The CIDRa domain from HB3var03 PfEMP1 bound to endothelial protein C receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOTHELIAL PROTEIN C RECEPTOR, ... | | 著者 | Lau, C.K.Y, Turner, L, Jespersen, J.S, Lowe, E.D, Petersen, B, Wang, C.W, Petersen, J.E.V, Lusingu, J, Theander, T.G, Lavstsen, T, Higgins, M.K. | | 登録日 | 2014-10-17 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural Conservation Despite Huge Sequence Diversity Allows Epcr Binding by the Pfemp1 Family Implicated in Severe Childhood Malaria.
Cell Host Microbe., 17, 2015
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4UIX
 | | N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4-dimethoxyphenyl)-N-(1,1-dioxo-1-thian-4-yl)-5-methyl-4-oxo-4H,5H-thieno-3,2-c-pyridine-2- carboxamide | | 分子名称: | 1,2-ETHANEDIOL, BROMODOMAIN-CONTAINING PROTEIN 4, CALCIUM ION, ... | | 著者 | Chung, C, Theodoulou, N.T, Bamborough, P, Humphreys, P.G. | | 登録日 | 2015-04-03 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | The Discovery of I-Brd9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
J.Med.Chem., 59, 2016
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9VG5
 | | NMR Solution Structure of the Monomeric Catalytic C-terminal Lobe of the E6AP HECT E3 Ubiquitin Ligase | | 分子名称: | Ubiquitin-protein ligase E3A | | 著者 | Dag, C, Lambert, M, Lohr, F, Lee, W, Kazar, A.E, Dotsch, V. | | 登録日 | 2025-06-12 | | 公開日 | 2025-06-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Solution Structure of the Monomeric Catalytic C-terminal Lobe of the E6AP HECT E3 Ubiquitin Ligase
To Be Published
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5YMR
 | | The Crystal Structure of IseG | | 分子名称: | 2-hydroxyethylsulfonic acid, Formate acetyltransferase, GLYCEROL | | 著者 | Lin, L, Zhang, J, Xing, M, Hua, G, Guo, C, Hu, Y, Wei, Y, Ang, E, Zhao, H, Zhang, Y, Yuchi, Z. | | 登録日 | 2017-10-22 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria.
Nat Commun, 10, 2019
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9KDP
 | | Crystal structure of monooxygenase PenE | | 分子名称: | Anthrone monooxygenase | | 著者 | Chi, C.B, Ma, M. | | 登録日 | 2024-11-03 | | 公開日 | 2025-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.592 Å) | | 主引用文献 | Functional Conservation and Divergence of AlpJ-Family Oxygenases Catalyzing C-C Bond Cleavage in Atypical Angucycline Biosynthesis.
Acs Chem.Biol., 2025
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7OKW
 | | 1.62A X-ray crystal structure of the conserved C-terminal (CCT) of human OSR1 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Bax, B.D, Elvers, K.T, Lipka-Lloyd, M, Mehellou, Y. | | 登録日 | 2021-05-18 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains.
Chembiochem, 23, 2022
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7OKU
 | | X-ray structure of soluble EPCR in P3121 space group | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Erausquin, E, Dichiara, M.G, Lopez-Sagaseta, J. | | 登録日 | 2021-05-18 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR).
Sci Rep, 12, 2022
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7OKV
 | | Crystal structure of soluble EPCR after exposure to the nonionic surfactant Polysorbate 20 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | | 著者 | Erausquin, E, Dichiara, M.G, Lopez-Sagaseta, J. | | 登録日 | 2021-05-18 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR).
Sci Rep, 12, 2022
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9R5Y
 | | Crystal structure of the C-terminal domain of human TNC in complex with Adhiron 52 | | 分子名称: | Adhiron, Tenascin | | 著者 | Gaule, T.G, Trinh, C, Simmons, K.J, Tomlinson, D.C, Maqbool, A. | | 登録日 | 2025-05-11 | | 公開日 | 2025-06-18 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Targeting Tenascin-C-Toll-like Receptor 4 signalling with Adhiron-derived small molecules - a viable strategy for reducing fibrosis in Systemic Sclerosis
To Be Published
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9KQP
 | | PSI-LHCI supercomplex binding with 10 Lhcas from C. subellipsoidea | | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3~{E},5~{E},7~{E})-6-methyl-8-[(6~{R})-2,2,6-trimethylcyclohexyl]octa-3,5,7-trien-2-one, ... | | 著者 | Tsai, P.-C, Kato, K, Shen, J.-R, Akita, F. | | 登録日 | 2024-11-26 | | 公開日 | 2025-02-26 | | 実験手法 | ELECTRON MICROSCOPY (1.92 Å) | | 主引用文献 | Structural study of the chlorophyll between Lhca8 and PsaJ in an Antarctica green algal photosystem I-LHCI supercomplex revealed by its atomic structure.
Biochim Biophys Acta Bioenerg, 1866, 2025
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9KQQ
 | | PSI-LHCI supercomplex binding with 8 Lhcas from C. subellipsoidea | | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ... | | 著者 | Tsai, P.-C, Kato, K, Shen, J.-R, Akita, F. | | 登録日 | 2024-11-26 | | 公開日 | 2025-02-26 | | 実験手法 | ELECTRON MICROSCOPY (2.06 Å) | | 主引用文献 | Structural study of the chlorophyll between Lhca8 and PsaJ in an Antarctica green algal photosystem I-LHCI supercomplex revealed by its atomic structure.
Biochim Biophys Acta Bioenerg, 1866, 2025
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7RIC
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7RID
 | | Griffithsin variant Y28A | | 分子名称: | Griffithsin | | 著者 | Zhao, G, Sun, J, Bewley, C.A. | | 登録日 | 2021-07-19 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity.
Acs Chem.Biol., 17, 2022
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8VS5
 | | Structure of catalytic domain of telomere resolvase, ResT, from Borrelia garinii | | 分子名称: | Telomere resolvase ResT | | 著者 | Semper, C, Savchenko, A, Watanabe, N, Center for Structural Biology of Infectious Diseases (CSBID) | | 登録日 | 2024-01-23 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.796 Å) | | 主引用文献 | Structure analysis of the telomere resolvase from the Lyme disease spirochete Borrelia garinii reveals functional divergence of its C-terminal domain.
Nucleic Acids Res., 52, 2024
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9MTU
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1CYI
 | | CYTOCHROME C6 | | 分子名称: | CADMIUM ION, CYTOCHROME C6, HEME C | | 著者 | Kerfeld, C.A, Yeates, T.O. | | 登録日 | 1995-05-09 | | 公開日 | 1996-01-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structure of chloroplast cytochrome c6 at 1.9 A resolution: evidence for functional oligomerization.
J.Mol.Biol., 250, 1995
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9MTV
 | | Crystal structure of an apo-ADC-1 triple mutant | | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, NITRATE ION | | 著者 | Smith, C.A, Stewart, N.K, Vakulenko, S.B. | | 登録日 | 2025-01-12 | | 公開日 | 2025-04-23 | | 最終更新日 | 2025-06-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Evolution of carbapenemase activity in the class C beta-lactamase ADC-1.
Mbio, 16, 2025
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9MTW
 | | Crystal structure of ADC-1-ertapenem complex | | 分子名称: | (2S,3R,4R)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, 1,2-ETHANEDIOL, ... | | 著者 | Smith, C.A, Stewart, N.K, Vakulenko, S.B. | | 登録日 | 2025-01-12 | | 公開日 | 2025-04-23 | | 最終更新日 | 2025-06-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Evolution of carbapenemase activity in the class C beta-lactamase ADC-1.
Mbio, 16, 2025
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8GCI
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6NL3
 | | Solution structure of human Coa6 | | 分子名称: | Cytochrome c oxidase assembly factor 6 homolog | | 著者 | Naik, M.T, Soma, S, Gohil, V. | | 登録日 | 2019-01-07 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase.
Cell Rep, 29, 2019
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1E29
 | | PSII associated cytochrome C549 from Synechocystis sp. | | 分子名称: | CALCIUM ION, CYTOCHROME C549, HEME C | | 著者 | Frazao, C, Enguita, F.J, Coelho, R, Sheldrick, G.M. | | 登録日 | 2000-05-19 | | 公開日 | 2001-05-04 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Crystal Structure of Low-Potential Cytochrome C549 from Synechocystis Sp. Pcc 6803 at 1.21A Resolution
J.Biol.Inorg.Chem., 6, 2001
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9MXI
 | | Crystal Structure of synthetic antibody, COP-2, in complex with the C-terminal domain of Clostridium perfringens Enterotoxin | | 分子名称: | COP-2 antibody heavy chain, COP-2 antibody light chain, GLYCEROL, ... | | 著者 | Ogbu, C.P, Kapoor, S, Vecchio, A.J. | | 登録日 | 2025-01-20 | | 公開日 | 2025-02-12 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of synthetic antibody, COP-2, in complex with the C-terminal domain of Clostridium perfringens Enterotoxin
To Be Published
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7OJS
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8QN0
 | | Soluble epoxide hydrolase in complex with RK3 | | 分子名称: | (3~{a}~{R},6~{a}~{S})-~{N}-[(2,4-dichlorophenyl)methyl]-5-(4-methylphenyl)sulfonyl-1,3,3~{a},4,6,6~{a}-hexahydropyrrolo[3,4-c]pyrrole-2-carboxamide, 1,2-ETHANEDIOL, Bifunctional epoxide hydrolase 2 | | 著者 | Kumar, A, Zhu, F, Ehrler, J.M.H, Li, F, Empel, C, Xu, Y, Atodiresei, I, Koenigs, R.M, Proschak, E, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2023-09-25 | | 公開日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Photosensitization enables Pauson-Khand-type reactions with nitrenes.
Science, 383, 2024
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