PDB: 56562 件ウェブページステータス検索Chemie searchBIRD

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6N5A	Crystal structure of an equine H7 hemagglutinin from A/equine/NY/49/73 (H7N7) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... 著者 Zhu, X, Wilson, I.A. 登録日 2018-11-21 公開日 2019-06-26 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses. Cell Rep, 27, 2019
8BPI	Human Gamma-D crystallin R36S mutant after UV illumination 分子名称: Gamma-crystallin D 著者 Yorke, B.A, Hill, J.A. 登録日 2022-11-16 公開日 2023-11-29 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin. Commun Chem, 7, 2024
2I66	Structural Basis for the Mechanistic Understanding Human CD38 Controlled Multiple Catalysis 分子名称: ADP-ribosyl cyclase 1, [(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4R,5S)-3,4,5-TRIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, [(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-1,6-DIHYDRO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE 著者 Liu, Q, Kriksunov, I.A, Graeff, R, Munshi, C, Lee, H.C, Hao, Q. 登録日 2006-08-28 公開日 2006-09-05 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis. J.Biol.Chem., 281, 2006
5KB5	Crystal structure of the adenosine kinase from Mus musculus in complex with adenosine and adenosine-diphosphate 分子名称: ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Adenosine kinase, ... 著者 Oliveira, R.R, Neto, R.M, Polo, C.C, Tonoli, C.C.C, Murakami, M.T, Franchini, K.G. 登録日 2016-06-02 公開日 2017-06-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the adenosine kinase from Mus musculus in complex with adenosine and adenosine-diphosphate To Be Published
5KC9	Crystal structure of the amino-terminal domain (ATD) of iGluR Delta-1 (GluD1) 分子名称: 1,2-ETHANEDIOL, 1,4-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Elegheert, J, Clay, J.E, Siebold, C, Aricescu, A.R. 登録日 2016-06-05 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for integration of GluD receptors within synaptic organizer complexes. Science, 353, 2016
6T0L	Crystal structure of CYP124 in complex with inhibitor compound 5' 分子名称: CHLORIDE ION, CYP124 in complex with inhibitor compound 5', DI(HYDROXYETHYL)ETHER, ... 著者 Bukhdruker, S, Marin, E, Varaksa, T, Gilep, A, Strushkevich, N, Borshchevskiy, V. 登録日 2019-10-03 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Metabolic Fate of Human Immunoactive Sterols in Mycobacterium tuberculosis. J.Mol.Biol., 433, 2021
8BU0	Crystal structure of an 8 repeat consensus TPR superhelix with calcium 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Liutkus, M, Rojas, A.L, Cortajarena, A.L. 登録日 2022-11-30 公開日 2023-12-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
6SAC	N-terminal expression tag remainder of human Carbonic Anhydrase II covalently modified by fragment 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 1-(1,3-dimethyl-1H-pyrazol-5-yl)methanamine, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-07-16 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II. Biomolecules, 10, 2020
8JV3	Structure of the SAR11 PotD in complex with glycine betaine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Spermidine/putrescine-binding periplasmic protein, ... 著者 Ma, Q, Liu, C. 登録日 2023-06-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Structure of the SAR11 PotD in complex with glycine betaine To Be Published
7UQB	Nucleoplasmic pre-60S intermediate of the Nog2 containing pre-rotation state from a SPB1-D52A strain with AlF4 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 25S rRNA, 5.8S rRNA, ... 著者 Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P. 登録日 2022-04-19 公開日 2023-03-15 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.43 Å) 主引用文献 rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly. Nat Commun, 14, 2023
8BBX	Structure of prolyl endoprotease from Aspergillus niger CBS 109712 in space group C222(1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoprotease endo-Pro, TETRAETHYLENE GLYCOL, ... 著者 Pijning, T, Vujicic-Zagar, A, Van der Laan, J.M, De Jong, R.M, Dijkstra, B.W. 登録日 2022-10-14 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and time-resolved mechanistic investigations of protein hydrolysis by the acidic proline-specific endoprotease from Aspergillus niger. Protein Sci., 33, 2024
8JV4	Structure of the SAR11 PotD in complex with DMSP 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(dimethyl-lambda~4~-sulfanyl)propanoic acid, GLYCEROL, ... 著者 Ma, Q, Liu, C. 登録日 2023-06-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.445 Å) 主引用文献 Structure of the SAR11 PotD in complex with DMSP To Be Published
8JV1	Structure of the SAR11 PotD in complex with GABA 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... 著者 Ma, Q, Liu, C. 登録日 2023-06-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.309 Å) 主引用文献 Structure of the SAR11 PotD in complex with GABA To Be Published
8B57	Structure of prolyl endoprotease from Aspergillus niger CBS 109712 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... 著者 Pijning, T, Vujicic-Zagar, A, Van der Laan, J.M, De Jong, R.M, Dijkstra, B.W. 登録日 2022-09-22 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structural and time-resolved mechanistic investigations of protein hydrolysis by the acidic proline-specific endoprotease from Aspergillus niger. Protein Sci., 33, 2024
6BXY	Menin in complex with MI-1481 分子名称: 1,2-ETHANEDIOL, 4-methyl-1-{[(2S)-5-oxomorpholin-2-yl]methyl}-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, DIMETHYL SULFOXIDE, ... 著者 Borkin, D, Klossowski, S, Pollock, J, Linhares, B, Cierpicki, T, Grembecka, J. 登録日 2017-12-19 公開日 2018-11-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction. J.Med.Chem., 61, 2018
8JV2	Structure of the SAR11 PotD in complex with proline 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, PROLINE, ... 著者 Ma, Q, Liu, C. 登録日 2023-06-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of the SAR11 PotD in complex with proline To Be Published
5JAU	Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening 分子名称: (2S)-3-(3-{[4-(2-aminoethoxy)-2',6-dimethyl[1,1'-biphenyl]-3-yl]amino}-1H-pyrazol-1-yl)-2-methoxypropan-1-ol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Day, P.J. 登録日 2016-04-12 公開日 2016-05-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening. J.Med.Chem., 59, 2016
6BZ2	Crystal structure of wild-type HIV-1 protease with a novel HIV-1 inhibitor GRL-14213A of 6-5-5-ring fused crown-like tetrahydropyranofuran as the P2-ligand, a cyclopropylaminobenzothiazole as the P2'-ligand and 3,5-difluorophenylmethyl as the P1-ligand 分子名称: (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... 著者 Wang, Y.-F, Agniswamy, J, Weber, I.T. 登録日 2017-12-22 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants. ChemMedChem, 13, 2018
5JBG	Crystal structure of chicken LGP2 with 5'ppp 26-mer hairpin RNA with 3' GG overhang and ADP-AlF4-Mg2+ at 2.0 A resolution. 分子名称: ADENOSINE-5'-DIPHOSPHATE, LGP2, MAGNESIUM ION, ... 著者 Cusack, S, Uchikawa, E. 登録日 2016-04-13 公開日 2016-06-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5. Mol.Cell, 62, 2016
5JCP	RhoGAP domain of ARAP3 in complex with RhoA in the transition state 分子名称: Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Bao, H, Li, F, Wang, C, Wang, N, Jiang, Y, Tang, Y, Wu, J, Shi, Y. 登録日 2016-04-15 公開日 2016-06-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3 J.Biol.Chem., 291, 2016
6N94	Methylmalonyl-CoA decarboxylase in complex with 2-nitronate-propionyl-amino(dethia)-CoA 分子名称: DI(HYDROXYETHYL)ETHER, IMIDAZOLE, Methylmalonyl-CoA decarboxylase, ... 著者 Stunkard, L.M, Dixon, A.D, Huth, T.J, Lohman, J.R. 登録日 2018-11-30 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Sulfonate/Nitro Bearing Methylmalonyl-Thioester Isosteres Applied to Methylmalonyl-CoA Decarboxylase Structure-Function Studies. J. Am. Chem. Soc., 141, 2019
5JAO	Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening 分子名称: 2'-chloro-6-methyl[1,1'-biphenyl]-3-amine, CALCIUM ION, CHLORIDE ION, ... 著者 Day, P.J. 登録日 2016-04-12 公開日 2016-05-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening. J.Med.Chem., 59, 2016
6QQC	Cryogenic temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 110 kGy 分子名称: CHLORIDE ION, Lysozyme C 著者 Gotthard, G, Aumonier, S, Royant, A. 登録日 2019-02-18 公開日 2019-06-19 最終更新日 2019-07-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Specific radiation damage is a lesser concern at room temperature. Iucrj, 6, 2019
6IM3	Crystal structure of a highly thermostable carbonic anhydrase from Persephonella marina EX-H1 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CALCIUM ION, Carbonic anhydrase (Carbonate dehydratase), ... 著者 Jin, M.S, Kim, S, Sung, J, Yeon, J, Choi, S.H. 登録日 2018-10-22 公開日 2019-07-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of a Highly Thermostable alpha-Carbonic Anhydrase from Persephonella marina EX-H1. Mol.Cells, 42, 2019
8I2B	Human SIRT6 in complex with inhibitor 7702 分子名称: N1-[[4-(4-aminophenyl)sulfanyl-3-(trifluoromethyl)phenyl]methoxy]benzene-1,4-dicarboxamide, NAD-dependent protein deacylase sirtuin-6, SULFATE ION, ... 著者 Wang, Y. 登録日 2023-01-14 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The SIRT6 in complex with inhibitor 7702 To Be Published

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