4O9K
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![BU of 4o9k by Molmil](/molmil-images/mine/4o9k) | Crystal structure of the CBS pair of a putative D-arabinose 5-phosphate isomerase from Methylococcus capsulatus in complex with CMP-Kdo | 分子名称: | Arabinose 5-phosphate isomerase, CYTIDINE 5'-MONOPHOSPHATE 3-DEOXY-BETA-D-GULO-OCT-2-ULO-PYRANOSONIC ACID, GLYCEROL | 著者 | Shabalin, I.G, Cooper, D.R, Shumilin, I.A, Zimmerman, M.D, Majorek, K.A, Hammonds, J, Hillerich, B.S, Nawar, A, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2014-01-02 | 公開日 | 2014-01-22 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure and kinetic properties of D-arabinose 5-phosphate isomerase from Methylococcus capsulatus To be Published
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2HEU
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![BU of 2heu by Molmil](/molmil-images/mine/2heu) | Atomic resolution structure of apo-form of RafE from Streptococcus pneumoniae | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, SODIUM ION, ... | 著者 | Paterson, N.G, Riboldi-Tunnicliffe, A, Mitchell, T.J, Isaacs, N.W. | 登録日 | 2006-06-22 | 公開日 | 2007-06-05 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | High resolution crystal structures of RafE from Streptococcus pneumoniae. To be Published
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3PWX
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![BU of 3pwx by Molmil](/molmil-images/mine/3pwx) | Structure of putative flagellar hook-associated protein from Vibrio parahaemolyticus | 分子名称: | MAGNESIUM ION, Putative flagellar hook-associated protein | 著者 | Ramagopal, U.A, Patskovsky, Y, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2010-12-09 | 公開日 | 2011-01-19 | 最終更新日 | 2021-02-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of putative flagellar hook-associated protein from Vibrio parahaemolyticus To be published
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4O9X
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![BU of 4o9x by Molmil](/molmil-images/mine/4o9x) | Crystal Structure of TcdB2-TccC3 | 分子名称: | MERCURY (II) ION, TcdB2, TccC3 | 著者 | Meusch, D, Gatsogiannis, C, Efremov, R.G, Lang, A.E, Hofnagel, O, Vetter, I.R, Aktories, K, Raunser, S. | 登録日 | 2014-01-03 | 公開日 | 2014-02-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Mechanism of Tc toxin action revealed in molecular detail. Nature, 508, 2014
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4KSP
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![BU of 4ksp by Molmil](/molmil-images/mine/4ksp) | Crystal Structure of Human B-raf bound to a DFG-out Inhibitor TAK-632 | 分子名称: | N-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]acetyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide, Serine/threonine-protein kinase B-raf | 著者 | Yano, J.K, Masanori, O. | 登録日 | 2013-05-17 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives. J.Med.Chem., 56, 2013
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2GU7
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![BU of 2gu7 by Molmil](/molmil-images/mine/2gu7) | E. coli methionine aminopeptidase unliganded, 1:0.5 | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase, SODIUM ION | 著者 | Ye, Q.Z. | 登録日 | 2006-04-28 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of catalysis by monometalated methionine aminopeptidase. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2Q1K
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![BU of 2q1k by Molmil](/molmil-images/mine/2q1k) | Cyrstal Structure of AscE from Aeromonas hydrophilla | 分子名称: | AscE | 著者 | Tan, Y.W, Yu, H.B, Leung, K.Y, Sivaraman, J, Mok, Y.K. | 登録日 | 2007-05-24 | 公開日 | 2008-06-03 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of AscE and induced burial regions in AscE and AscG upon formation of the chaperone needle-subunit complex of type III secretion system in Aeromonas hydrophila. Protein Sci., 17, 2008
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3EZ5
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![BU of 3ez5 by Molmil](/molmil-images/mine/3ez5) | Cocrystal structure of Bacillus fragment DNA polymerase I with duplex DNA , dCTP, and zinc (closed form). | 分子名称: | 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*DAP*DTP*DTP*DCP*DGP*DAP*DGP*DTP*DCP*DAP*DGP*DG)-3', 5'-D(*DCP*DCP*DTP*DGP*DAP*DCP*DTP*DCP*DG)-3', ... | 著者 | Warren, J.J, Wu, E.Y, Golosov, A.A, Karplus, M, Beese, L.S. | 登録日 | 2008-10-22 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis. Structure, 18, 2010
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4H9L
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![BU of 4h9l by Molmil](/molmil-images/mine/4h9l) | |
2Q1X
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![BU of 2q1x by Molmil](/molmil-images/mine/2q1x) | |
3Q12
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![BU of 3q12 by Molmil](/molmil-images/mine/3q12) | Pantoate-beta-alanine ligase from Yersinia pestis in complex with pantoate. | 分子名称: | CHLORIDE ION, PANTOATE, Pantoate--beta-alanine ligase | 著者 | Osipiuk, J, Maltseva, N, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-12-16 | 公開日 | 2011-02-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Pantoate-beta-alanine ligase from Yersinia pestis. To be Published
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4HA5
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![BU of 4ha5 by Molmil](/molmil-images/mine/4ha5) | Structure of BACE Bound to (S)-3-(5-(2-imino-1,4-dimethyl-6-oxohexahydropyrimidin-4-yl)thiophen-3-yl)benzonitrile | 分子名称: | 3-{5-[(2E,4S)-2-imino-1,4-dimethyl-6-oxohexahydropyrimidin-4-yl]thiophen-3-yl}benzonitrile, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Strickland, C, Mandal, M. | 登録日 | 2012-09-25 | 公開日 | 2012-10-17 | 最終更新日 | 2012-11-21 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation. J.Med.Chem., 55, 2012
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4OGF
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![BU of 4ogf by Molmil](/molmil-images/mine/4ogf) | |
2Q2X
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3F2M
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![BU of 3f2m by Molmil](/molmil-images/mine/3f2m) | Urate oxidase complexed with 8-azaxanthine at 150 MPa | 分子名称: | 8-AZAXANTHINE, SODIUM ION, Uricase | 著者 | Colloc'h, N, Girard, E, Kahn, R, Fourme, R. | 登録日 | 2008-10-30 | 公開日 | 2009-11-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure-function perturbation and dissociation of tetrameric urate oxidase by high hydrostatic pressure. Biophys.J., 98, 2010
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4OLR
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![BU of 4olr by Molmil](/molmil-images/mine/4olr) | [Leu-5]-Enkephalin mutant - YVVFV | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, [Leu-5]-Enkephalin mutant - YVVFV | 著者 | Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C. | 登録日 | 2014-01-24 | 公開日 | 2014-07-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. J.Phys.Chem.B, 118, 2014
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2Q36
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![BU of 2q36 by Molmil](/molmil-images/mine/2q36) | Actin Dimer Cross-linked between Residues 191 and 374 and complexed with Kabiramide C | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Sawaya, M.R, Pashkov, I, Kudryashov, D.S, Reisler, E, Yeates, T.O. | 登録日 | 2007-05-29 | 公開日 | 2007-06-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Multiple crystal structures of actin dimers and their implications for interactions in the actin filament. Acta Crystallogr.,Sect.D, 64, 2008
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4HC7
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![BU of 4hc7 by Molmil](/molmil-images/mine/4hc7) | Crystal structure of the full DNA binding domain of GATA3-complex 2 | 分子名称: | DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | 著者 | Chen, Y, Bates, D.L, Dey, R, Chen, L. | 登録日 | 2012-09-28 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation. Cell Rep, 2, 2012
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4HDM
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![BU of 4hdm by Molmil](/molmil-images/mine/4hdm) | Crystal Structure of ArsAB in Complex with p-cresol | 分子名称: | 1,2-ETHANEDIOL, ArsA, ArsB, ... | 著者 | Newmister, S.A, Chan, C.H, Escalante-Semerena, J.C, Rayment, I. | 登録日 | 2012-10-02 | 公開日 | 2012-10-24 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights into the Function of the Nicotinate Mononucleotide:phenol/p-cresol Phosphoribosyltransferase (ArsAB) Enzyme from Sporomusa ovata. Biochemistry, 51, 2012
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5RSD
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![BU of 5rsd by Molmil](/molmil-images/mine/5rsd) | PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000000331945 | 分子名称: | Non-structural protein 3, quinazolin-4-amine | 著者 | Correy, G.J, Young, I.D, Thompson, M.C, Fraser, J.S. | 登録日 | 2020-09-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021
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2GU6
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![BU of 2gu6 by Molmil](/molmil-images/mine/2gu6) | |
4GPE
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![BU of 4gpe by Molmil](/molmil-images/mine/4gpe) | Crystal Structure of Benzoylformate Decarboxylase Mutant L403M | 分子名称: | 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Benzoylformate decarboxylase, CALCIUM ION, ... | 著者 | Novak, W.R.P, Andrews, F.H, Tom, A.R, Gunderman, P.R, McLeish, M.J. | 登録日 | 2012-08-20 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | A bulky hydrophobic residue is not required to maintain the v-conformation of enzyme-bound thiamin diphosphate. Biochemistry, 52, 2013
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3FHX
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![BU of 3fhx by Molmil](/molmil-images/mine/3fhx) | Crystal structure of D235A mutant of human pyridoxal kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Safo, M.K, Gandhi, A.K, Musayev, F.N, Ghatge, M, Di Salvo, M.L, Schirch, V. | 登録日 | 2008-12-10 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase. Biochem.Biophys.Res.Commun., 381, 2009
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4OO8
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![BU of 4oo8 by Molmil](/molmil-images/mine/4oo8) | Crystal structure of Streptococcus pyogenes Cas9 in complex with guide RNA and target DNA | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*CP*CP*AP*GP*CP*CP*AP*AP*GP*CP*GP*CP*AP*CP*CP*TP*AP*AP*TP*TP*TP*CP*C)-3'), RNA (97-MER) | 著者 | Nishimasu, H, Ishitani, R, Nureki, O. | 登録日 | 2014-01-31 | 公開日 | 2014-02-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of Cas9 in complex with guide RNA and target DNA Cell(Cambridge,Mass.), 156, 2014
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5RST
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![BU of 5rst by Molmil](/molmil-images/mine/5rst) | PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINC000000332673 | 分子名称: | 5-hydroxypyridine-3-carboxylic acid, Non-structural protein 3 | 著者 | Correy, G.J, Young, I.D, Thompson, M.C, Fraser, J.S. | 登録日 | 2020-09-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv, 7, 2021
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