PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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5B42	Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL. 分子名称: CADMIUM ION, DI(HYDROXYETHYL)ETHER, DNA mismatch repair protein MutL 著者 Fukui, K, Baba, S, Kumasaka, T, Yano, T. 登録日 2016-03-30 公開日 2016-07-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Features and Functional Dependency on beta-Clamp Define Distinct Subfamilies of Bacterial Mismatch Repair Endonuclease MutL J.Biol.Chem., 291, 2016
3FLY	P38 kinase crystal structure in complex with 6-(2,4-difluoro-phenoxy)-2-isopropylamino-8-methyl-8h-pyrido[2,3-d]pyrimidin-7-one 分子名称: 6-(2,4-difluorophenoxy)-8-methyl-2-[(1-methylethyl)amino]pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-19 公開日 2009-12-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Discovery of Pamapimod, R1503 and R1487 as Orally Bioavailable and Highly Selective Inhibitors of p38 Map Kinase To be Published
3FMM	P38 kinase crystal structure in complex with RO6226 分子名称: 6-(2,4-difluorophenoxy)-N-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-amine, Mitogen-activated protein kinase 14 著者 Kuglstatter, A, Ghate, M. 登録日 2008-12-22 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 P38 kinase crystal structure in complex with RO6226 To be Published
4QFT	Structure of COP9 signalosome complex subunit 6 分子名称: COP9 signalosome complex subunit 6 著者 Birol, M, Hoh, F, Dumas, C, Echalier, A. 登録日 2014-05-21 公開日 2014-09-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer. PLoS ONE, 9, 2014
4QG6	crystal structure of PKM2-Y105E mutant 分子名称: PROLINE, Pyruvate kinase PKM 著者 Wang, P, Sun, C, Zhu, T, Xu, Y. 登録日 2014-05-22 公開日 2015-02-25 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3.207 Å) 主引用文献 Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
3ICD	STRUCTURE OF A BACTERIAL ENZYME REGULATED BY PHOSPHORYLATION, ISOCITRATE DEHYDROGENASE 分子名称: ISOCITRATE DEHYDROGENASE 著者 Hurley, J.H, Thorsness, P.E, Ramalingam, V, Helmers, N.H, Koshlandjunior, D.E, Stroud, R.M. 登録日 1989-12-28 公開日 1991-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of a bacterial enzyme regulated by phosphorylation, isocitrate dehydrogenase. Proc.Natl.Acad.Sci.USA, 86, 1989
2RG5	Phenylalanine pyrrolotriazine p38 alpha map kinase inhibitor compound 11B 分子名称: Mitogen-activated protein kinase 14, N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 著者 Sack, J.S. 登録日 2007-10-02 公開日 2008-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Design, Synthesis, and Anti-inflammatory Properties of Orally Active 4-(Phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha Mitogen-Activated Protein Kinase Inhibitors J.Med.Chem., 51, 2008
5BO0	Crystal structure of Human MCM2 HBD and ASF1b chaperoning a histone H3.2-H4 dimer 分子名称: DNA replication licensing factor MCM2, GLYCEROL, Histone H3.2, ... 著者 Huang, H, Patel, D.J. 登録日 2015-05-26 公開日 2015-06-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.906 Å) 主引用文献 A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks. Nat.Struct.Mol.Biol., 22, 2015
5BMU	The crystal structure of the GST-like domains complex of AIMP3-EPRS mutant C92SC105SC123S 分子名称: Eukaryotic translation elongation factor 1 epsilon-1, Glutamate--tRNA ligase 著者 Cho, H.J, Kang, B.S. 登録日 2015-05-23 公開日 2015-10-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Assembly of Multi-tRNA Synthetase Complex via Heterotetrameric Glutathione Transferase-homology Domains J.Biol.Chem., 290, 2015
3FCE	Crystal Structure of Bacillus cereus D-alanyl Carrier Protein Ligase DltA in Complex with ATP: Implications for Adenylation Mechanism 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-alanine--poly(phosphoribitol) ligase subunit 1 著者 Osman, K.T, Du, L, He, Y, Luo, Y. 登録日 2008-11-21 公開日 2009-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Bacillus cereus D-alanyl carrier protein ligase (DltA) in complex with ATP. J.Mol.Biol., 388, 2009
5YC2	Crystal structure of inner membrane protein Bqt4 in complex with telomeric protein Rap1 分子名称: DNA-binding protein rap1, Ubiquitin-like protein SMT3,Bouquet formation protein 4 著者 Chen, Y, Hu, C. 登録日 2017-09-06 公開日 2018-11-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast. Nucleic Acids Res., 47, 2019
4L0B	Tankyrase 2 in complex with 4'-dimethylamino flavone 分子名称: 2-[4-(dimethylamino)phenyl]-4H-chromen-4-one, GLYCEROL, SULFATE ION, ... 著者 Narwal, M, Haikarainen, T, Lehtio, L. 登録日 2013-05-31 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
5YDG	Crystal structure of the Arabidopsis thaliana chloroplast RNA editing factors 2(MORF2) 分子名称: Multiple organellar RNA editing factor 2, chloroplastic 著者 Wang, X, Yang, J.Y, Wang, Y.L, Gao, Y.S. 登録日 2017-09-13 公開日 2017-12-20 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.405 Å) 主引用文献 Crystal structure of the chloroplast RNA editing factor MORF2 Biochem. Biophys. Res. Commun., 495, 2018
4L0V	Tankyrase 2 in complex with 4'-chloro flavone 分子名称: 2-(4-chlorophenyl)-4H-chromen-4-one, GLYCEROL, SULFATE ION, ... 著者 Narwal, M, Haikarainen, T, Lehtio, L. 登録日 2013-06-01 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
3D7Z	Crystal Structure of P38 Kinase in Complex with a biphenyl amide inhibitor 分子名称: GLYCEROL, Mitogen-activated protein kinase 14, N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide, ... 著者 Somers, D.O, Patel, S. 登録日 2008-05-22 公開日 2008-07-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity. Bioorg.Med.Chem.Lett., 18, 2008
5YIU	Caulobacter crescentus GcrA DNA-binding domain (DBD) 分子名称: Cell cycle regulatory protein GcrA 著者 Wu, X, Zhang, Y. 登録日 2017-10-06 公開日 2018-03-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
5YIW	Caulobacter crescentus GcrA DNA-binding domain (DBD) in complex with methylated dsDNA (crystal form 2) 分子名称: (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*CP*TP*GP*(6MA)P*TP*TP*CP*GP*C)-3'), ... 著者 Wu, X, Zhang, Y. 登録日 2017-10-06 公開日 2018-03-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
2RSU	Alternative structure of Ubiquitin 分子名称: Ubiquitin 著者 Kitazawa, S, Kameda, T, Yagi-Utsumi, M, Kato, K, Kitahara, R. 登録日 2012-06-15 公開日 2013-03-27 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Q41N Variant of Ubiquitin as a Model for the Alternatively Folded N2 State of Ubiquitin Biochemistry, 52, 2013
4LMM	Crystal structure of NHERF1 PDZ1 domain complexed with the CXCR2 C-terminal tail in P21 space group 分子名称: ACETIC ACID, CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 著者 Jiang, Y, Lu, G, Wu, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. 登録日 2013-07-10 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping. Plos One, 8, 2013
3CTQ	Structure of MAP kinase p38 in complex with a 1-o-tolyl-1,2,3-triazole-4-carboxamide 分子名称: Mitogen-activated protein kinase 14, N-benzyl-1-[5-({5-tert-butyl-2-methoxy-3-[(methylsulfonyl)amino]phenyl}carbamoyl)-2-methylphenyl]-1H-1,2,3-triazole-4-carboxamide 著者 Qian, K. 登録日 2008-04-14 公開日 2008-05-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-based design and subsequent optimization of 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase. Bioorg.Med.Chem.Lett., 18, 2008
4Z4K	Crystal structure of GFP-TAX1BP1 UBZ1+2 domain fusion protein 分子名称: Green fluorescent protein,Tax1-binding protein 1, ZINC ION 著者 Rohaim, A, Kawasaki, M, Wakatsuki, S. 登録日 2015-04-02 公開日 2016-04-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1. Febs J., 283, 2016
4QG9	crystal structure of PKM2-R399E mutant 分子名称: ACETATE ION, MAGNESIUM ION, Pyruvate kinase PKM 著者 Wang, P, Sun, C, Zhu, T, Xu, Y. 登録日 2014-05-22 公開日 2015-02-25 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.381 Å) 主引用文献 Structural insight into mechanisms for dynamic regulation of PKM2. Protein Cell, 6, 2015
4ZCA	Eg5 motor domain mutant Y231F 分子名称: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION 著者 Luo, M, Parke, C, Worthylake, D. 登録日 2015-04-15 公開日 2016-06-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Eg5 To Be Published
8H4J	Crystal Structure of AzoR-FMN-Lyb24 complex 分子名称: FLAVIN MONONUCLEOTIDE, FMN dependent NADH:quinone oxidoreductase, ~{N}-(3-methylsulfanylphenyl)-4~{H}-cyclopenta[b]quinolin-9-amine 著者 Huang, W. 登録日 2022-10-10 公開日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of AzoR-FMN-Lyb24 complex To Be Published
4QKY	Crystal Structure Analysis of the Membrane Transporter FhaC 分子名称: Filamentous hemagglutinin transporter protein FhaC, PHOSPHATE ION 著者 Maier, T, Clantin, B, Gruss, F, Dewitte, F, Delattre, A.S, Jacob-Dubuisson, F, Hiller, S, Villeret, V. 登録日 2014-06-10 公開日 2014-10-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Conserved Omp85 lid-lock structure and substrate recognition in FhaC Nat Commun, 6, 2015

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