PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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1K6C	LACK OF SYNERGY FOR INHIBITORS TARGETING A MULTI-DRUG RESISTANT HIV-1 PROTEASE 分子名称: ACETATE ION, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, POL polyprotein 著者 Schiffer, C.A. 登録日 2001-10-15 公開日 2002-02-06 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease. Protein Sci., 11, 2002
1K76	Solution Structure of the C-terminal Sem-5 SH3 Domain (Minimized Average Structure) 分子名称: SEX MUSCLE ABNORMAL PROTEIN 5 著者 Ferreon, J, Volk, D, Luxon, B, Gorenstein, D, Hilser, V. 登録日 2001-10-18 公開日 2003-05-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure, Dynamics and Thermodynamics of the Native State Ensemble of Sem-5 C-Terminal SH3 Domain Biochemistry, 42, 2003
2DKK	Structure/Function studies of Cytochrome P450 158A1 from Streptomyces Coelicolor A3(2) 分子名称: IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 著者 Zhao, B. 登録日 2006-04-12 公開日 2007-04-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2. Biochemistry, 46, 2007
2XIK	Structure of Human YSK1 (Yeast Sps1-Ste20-related Kinase 1) 分子名称: 1,2-ETHANEDIOL, 5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, SERINE/THREONINE PROTEIN KINASE 25 著者 Muniz, J.R.C, Rellos, P, Ugochukwu, E, Vollmar, M, Allerston, C, Chaikuad, A, Savitsky, P, Berridge, G, Brenner, B, Elkins, J.M, Daga, N, Gileadi, O, Mahajan, P, Shrestha, B, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S. 登録日 2010-06-30 公開日 2010-07-14 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structure of Human Ysk1 (Yeast Sps1-Ste20-Related Kinase 1) To be Published
1YNR	Crystal structure of the cytochrome c-552 from Hydrogenobacter thermophilus at 2.0 resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Cytochrome c-552, HEME C, ... 著者 Travaglini-Allocatelli, C, Gianni, S, Dubey, V.K, Borgia, A, Di Matteo, A, Bonivento, D, Cutruzzola, F, Bren, K.L, Brunori, M. 登録日 2005-01-25 公開日 2005-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Obligatory Intermediate in the Folding Pathway of Cytochrome c552 from Hydrogenobacter thermophilus J.Biol.Chem., 280, 2005
2DOC	Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2 分子名称: Neural cell adhesion molecule 2 著者 Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-28 公開日 2006-10-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2 To be Published
1YPU	Human Oxidized Low Density Lipoprotein Receptor LOX-1 C2 Space Group 分子名称: oxidised low density lipoprotein (lectin-like) receptor 1 著者 Park, H, Adsit, F.G, Boyington, J.C. 登録日 2005-01-31 公開日 2005-02-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1. J.Biol.Chem., 280, 2005
1YPH	High resolution structure of bovine alpha-chymotrypsin 分子名称: CHYMOTRYPSIN A, chain A, chain B, ... 著者 Razeto, A, Galunsky, B, Kasche, V, Wilson, K.S, Lamzin, V.S. 登録日 2005-01-31 公開日 2006-02-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 High resolution structure of native bovine alpha-chymotrypsin To be Published
1K5B	Crystal Structure of Human Angiogenin Variant des(121-123) 分子名称: Angiogenin, CITRIC ACID 著者 Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. 登録日 2001-10-10 公開日 2002-03-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Biochemistry, 41, 2002
1K59	Crystal Structure of Human Angiogenin Variant Q117G 分子名称: CITRIC ACID, angiogenin 著者 Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. 登録日 2001-10-10 公開日 2002-03-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Biochemistry, 41, 2002
1YQP	T268N mutant cytochrome domain of flavocytochrome P450 BM3 分子名称: Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Clark, J.P, Miles, C.S, Mowat, C.G, Walkinshaw, M.D, Reid, G.A, Daff, S.N, Chapman, S.K. 登録日 2005-02-02 公開日 2006-01-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The role of Thr268 and Phe393 in cytochrome P450 BM3. J.Inorg.Biochem., 100, 2006
2DO4	Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3 分子名称: Squamous cell carcinoma antigen recognized by T-cells 3 著者 Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-04-27 公開日 2007-04-17 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the RNA binding domain of squamous cell carcinoma antigen recognized by T cells 3 To be Published
1YRD	X-ray crystal structure of PERDEUTERATED Cytochrome P450cam 分子名称: CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... 著者 Meilleur, F, Dauvergne, M.-T, Schlichting, I, Myles, D.A.A. 登録日 2005-02-03 公開日 2005-02-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr.,Sect.D, 61, 2005
3H0Y	Aurora A in complex with a bisanilinopyrimidine 分子名称: 2-chloro-N-[4-({5-fluoro-2-[(4-hydroxyphenyl)amino]pyrimidin-4-yl}amino)phenyl]benzamide, SULFATE ION, Serine/threonine-protein kinase 6 著者 Wiesmann, C, Ultsch, M.H, Cochran, A.G. 登録日 2009-04-10 公開日 2009-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B. J.Med.Chem., 52, 2009
2DOQ	crystal structure of Sfi1p/Cdc31p complex 分子名称: CALCIUM ION, Cell division control protein 31, SFI1p 著者 Li, S, Sandercock, A.M, Conduit, P.T, Robinson, C.V, Williams, R.L, Kilmartin, J.V. 登録日 2006-05-03 公開日 2006-06-27 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural role of Sfi1p-centrin filaments in budding yeast spindle pole body duplication. J.Cell Biol., 173, 2006
1YMB	HIGH RESOLUTION STUDY OF THE THREE-DIMENSIONAL STRUCTURE OF HORSE HEART METMYOGLOBIN 分子名称: METMYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Evans, S.V, Brayer, G.D. 登録日 1993-09-27 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High-resolution study of the three-dimensional structure of horse heart metmyoglobin. J.Mol.Biol., 213, 1990
1YU9	GppNHp-Bound Rab4A 分子名称: GTP-binding protein, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Eathiraj, S, Pan, X, Ritacco, C, Lambright, D.G. 登録日 2005-02-13 公開日 2005-07-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural basis of family-wide Rab GTPase recognition by rabenosyn-5. Nature, 436, 2005
2DGX	Solution structure of the RNA recognition motif in KIAA0430 protein 分子名称: KIAA0430 protein 著者 Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2006-03-16 公開日 2006-09-16 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the RNA recognition motif in KIAA0430 protein To be Published
1YM4	Crystal structure of human beta secretase complexed with NVP-AMK640 分子名称: Beta-secretase 1, NVP-AMK640 INHIBITOR 著者 Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. 登録日 2005-01-20 公開日 2006-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics J.Med.Chem., 48, 2005
1YMW	The study of reductive unfolding pathways of RNase A (Y92G mutant) 分子名称: Ribonuclease pancreatic 著者 Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. 登録日 2005-01-21 公開日 2006-01-31 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
2YAC	Crystal structure of Polo-like kinase 1 in complex with NMS-P937 分子名称: 1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO]-4,5-DIHYDROPYRIMIDO[5,4-G]INDAZOLE-3-CARBOXAMIDE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ... 著者 Bertrand, J.A, Bossi, R.T. 登録日 2011-02-18 公開日 2011-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nms-P937, a 4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline Derivative as Potent and Selective Polo-Like Kinase 1 Inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
2YEX	Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors 分子名称: 5-METHYL-8-(1H-PYRROL-2-YL)[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1(2H)-ONE, GLYCEROL, SERINE/THREONINE-PROTEIN KINASE CHK1, ... 著者 Read, J.A, Breed, J, Haye, H, McCall, E, Vallentine, A, White, A. 登録日 2011-03-31 公開日 2012-03-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Synthesis and Evaluation of Triazolones as Checkpoint Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
1K68	Crystal Structure of the Phosphorylated Cyanobacterial Phytochrome Response Regulator RcpA 分子名称: MAGNESIUM ION, Phytochrome Response Regulator RcpA 著者 Benda, C, Scheufler, C, Tandeau de Marsac, N, Gaertner, W. 登録日 2001-10-15 公開日 2003-12-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of two cyanobacterial response regulators in apo- and phosphorylated form reveal a novel dimerization motif of phytochrome-associated response regulators Biophys.J., 87, 2004
1K5A	Crystal structure of human angiogenin double variant I119A/F120A 分子名称: Angiogenin 著者 Leonidas, D.D, Shapiro, R, Subbarao, G.V, Russo, A, Acharya, K.R. 登録日 2001-10-10 公開日 2002-03-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency. Biochemistry, 41, 2002
1YRN	CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA 分子名称: DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*TP*AP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*TP*AP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT A1 HOMEODOMAIN), ... 著者 Li, T, Stark, M.R, Johnson, A.D, Wolberger, C. 登録日 1995-11-02 公開日 1996-01-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA. Science, 270, 1995

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