PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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5C05	Crystal Structure of Gamma-terpinene Synthase from Thymus vulgaris 分子名称: 1,2-ETHANEDIOL, Putative gamma-terpinene synthase 著者 Parthier, C.P, Rudolph, K, Muller, Y.A, Mueller-Uri, F. 登録日 2015-06-12 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Expression, crystallization and structure elucidation of gamma-terpinene synthase from Thymus vulgaris. Acta Crystallogr.,Sect.F, 72, 2016
6BBS	Joint X-ray/neutron structure of human carbonic anhydrase II in complex with brinzolamide 分子名称: (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION 著者 Kovalevsky, A, Aggarwal, M, McKenna, R. 登録日 2017-10-19 公開日 2018-02-28 最終更新日 2024-03-13 実験手法 NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION 主引用文献 "To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation. Structure, 26, 2018
6BBZ	Room temperature neutron/X-ray structure of sisomicin bound AAC-VIa 分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, AAC 3-VI protein, MAGNESIUM ION 著者 Cuneo, M.J, Kumar, P. 登録日 2017-10-20 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 NEUTRON DIFFRACTION (1.9 Å), X-RAY DIFFRACTION 主引用文献 A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
6BC4	Cryo X-ray structure of acetyl coenzyme A bound AAC-VIa 分子名称: AAC 3-VI protein, ACETYL COENZYME *A 著者 Cuneo, M.J, Kumar, P, Serpersu, E.H. 登録日 2017-10-20 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.049 Å) 主引用文献 A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
6APZ	Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 3-hydroxy-phenyldiketoacid 分子名称: (2Z)-2-hydroxy-4-(3-hydroxyphenyl)-4-oxobut-2-enoic acid, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2017-08-18 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.254 Å) 主引用文献 Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58, 2018
5F3F	Crystal structure of para-biphenyl-2-methyl-3'-methyl amide mannoside bound to FimH lectin domain 分子名称: 3-[4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-methyl-phenyl]-~{N}-methyl-benzamide, Protein FimH 著者 Klein, R.D, Hultgren, S.J. 登録日 2015-12-02 公開日 2016-12-07 最終更新日 2024-01-03 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections. J.Med.Chem., 59, 2016
6AXP	Structure of cetuximab with aminoheptanoic acid-linked n-octylarginine meditope variant 分子名称: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ... 著者 Bzymek, K.P, Williams, J.C. 登録日 2017-09-07 公開日 2017-12-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.484 Å) 主引用文献 Meditope-Fab interaction: threading the hole. Acta Crystallogr F Struct Biol Commun, 73, 2017
5CBP	Crystal Structure of Conjoint Pyrococcus furiosus L-asparaginase at 37 degree C 分子名称: CITRATE ANION, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Sharma, P, Yadav, S.P, Tomar, R, Kundu, B, Ashish, F. 登録日 2015-07-01 公開日 2016-07-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.358 Å) 主引用文献 Heat induces end to end repetitive association in P. furiosus L-asparaginase which enables its thermophilic property. Sci Rep, 10, 2020
4XBS	2-deoxyribose-5-phosphate aldolase mutant - E78K 分子名称: Deoxyribose-phosphate aldolase 著者 Jiao, X.-C, Pan, J, Xu, G.-C, Kong, X.-D, Chen, Q, Zhang, Z.-J, Xu, J.-H. 登録日 2014-12-17 公開日 2015-11-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Efficient synthesis of a statin precursor in high space-time yield by a new aldehyde-tolerant aldolase identified from Lactobacillus brevis Catalysis Science And Technology, 5, 2015
4XQD	X-ray structure analysis of xylanase-WT at pH4.0 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endo-1,4-beta-xylanase 2, IODIDE ION 著者 Wan, Q, Park, J.M, Riccardi, D.M, Hanson, L.B, Fisher, Z, Smith, J.C, Ostermann, A, Schrader, T, Graham, D.E, Coates, L, Langan, P, Kovalevsky, A.Y. 登録日 2015-01-19 公開日 2015-09-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
4XE9	Crystal structure of the NanB sialidase from Streptococcus pneumoniae in complex with Optactin 分子名称: (1s,3R,4S)-1-[(cyclohexylamino)methyl]-3,4-dihydroxycyclopentanesulfonic acid, DIMETHYL SULFOXIDE, Sialidase B 著者 Brear, P. 登録日 2014-12-23 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 The Hunt for Serendipitous Allosteric Sites: Discovery of a novel allosteric inhibitor of the bacterial sialidase NanB To be published
5CJF	The crystal structure of the human carbonic anhydrase XIV in complex with a 1,1'-biphenyl-4-sulfonamide inhibitor. 分子名称: 4'-(4-aminobenzoyl)biphenyl-4-sulfonamide, Carbonic anhydrase 14, GLYCEROL, ... 著者 Alterio, V, De Simone, G. 登録日 2015-07-14 公開日 2015-11-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. J.Med.Chem., 58, 2015
6BDP	Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000071 (Compound 9c) Complex 分子名称: (4-{[(3R)-1-benzylpyrrolidin-3-yl]amino}-2-nitrophenyl)methanol, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein 著者 Taylor, A.B. 登録日 2017-10-24 公開日 2018-10-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents. ACS Med Chem Lett, 9, 2018
7B0B	Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, IGK@ protein, ... 著者 Borenstein-Katz, A, Diskin, R. 登録日 2020-11-19 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants. Immunity, 56, 2023
4XSM	Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with D-talitol 分子名称: D-altritol, D-tagatose 3-epimerase, MANGANESE (II) ION 著者 Yoshida, H, Yoshihara, A, Ishii, T, Izumori, K, Kamitori, S. 登録日 2015-01-22 公開日 2016-01-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates Appl. Microbiol. Biotechnol., 100, 2016
6B67	Human PP2Calpha (PPM1A) complexed with cyclic peptide c(MpSIpYVA) 分子名称: CALCIUM ION, Protein phosphatase 1A, cyclic peptide c(MpSIpYVA) 著者 Dyda, F, Kosek, D. 登録日 2017-10-01 公開日 2018-04-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A trapped human PPM1A-phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity. J. Biol. Chem., 293, 2018
6APN	HLA-A*0201 single chain trimer with HPV.16 E7 peptide LLMGTLGIV 分子名称: Beta-2-microglobulin--HLA-A*0201--HPV.16 E7 peptide LLMGTLGIV chimera 著者 Finton, K.A.K. 登録日 2017-08-17 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Effects of HLA single chain trimer design on peptide presentation and stability To Be Published
2DKD	Crystal structure of N-acetylglucosamine-phosphate mutase, a member of the alpha-D-phosphohexomutase superfamily, in the product complex 分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, PHOSPHATE ION, Phosphoacetylglucosamine mutase, ... 著者 Nishitani, Y, Maruyama, D, Nonaka, T, Kita, A, Fukami, T.A, Mio, T, Yamada-Okabe, H, Yamada-Okabe, T, Miki, K. 登録日 2006-04-07 公開日 2006-05-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of N-Acetylglucosamine-phosphate Mutase, a Member of the {alpha}-D-Phosphohexomutase Superfamily, and Its Substrate and Product Complexes. J.Biol.Chem., 281, 2006
6AUG	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with SR16832 分子名称: 2-chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid 著者 Shang, J, Kojetin, D.J. 登録日 2017-08-31 公開日 2018-09-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, 2018
6AVA	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox 分子名称: Insectotoxin-I1 著者 Gewe, M.M, Rupert, P, Strong, R.K. 登録日 2017-09-01 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
6AW0	Crystal structure of CEACAM3 L44Q 分子名称: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, ... 著者 Bonsor, D.A, Sundberg, E.J. 登録日 2017-09-05 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA. EMBO J., 37, 2018
5FEF	Crystal structure of the allergen profilin (Zea m 12) 分子名称: GLYCEROL, Profilin-5 著者 Mares-Mejia, I, Rodriguez-Romero, A. 登録日 2015-12-16 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms. Sci Rep, 6, 2016
5FDS	Crystal structure of the monomeric allergen profilin (Hev b 8) 分子名称: GLYCEROL, Profilin-2, SULFATE ION 著者 Mares-Mejia, I, Rodriguez-Romero, A. 登録日 2015-12-16 公開日 2016-09-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the IgE mediated responses induced by the allergens Hev b 8 and Zea m 12 in their dimeric forms. Sci Rep, 6, 2016
6AY7	Cartilage homing cysteine-dense-peptides 分子名称: CHLORIDE ION, Potassium channel toxin alpha-KTx 3.5, SULFATE ION, ... 著者 Gewe, M.M, Strong, R.K. 登録日 2017-09-07 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Cartilage homing cysteine-dense-peptides To Be Published
6BAH	Trastuzumab Fab v3 with 5-diphenyl meditope variant 分子名称: Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain,IGH@ protein, ... 著者 Bzymek, K.P, King, J.D, Williams, J.C. 登録日 2017-10-12 公開日 2018-09-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29, 2018

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