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2TMA
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TROPOMYOSIN CRYSTAL STRUCTURE AND MUSCLE REGULATION. APPENDIX. CONSTRUCTION OF AN ATOMIC MODEL FOR TROPOMYOSIN AND IMPLICATIONS FOR INTERACTIONS WITH ACTIN
分子名称: TROPOMYOSIN
著者Phillips Jr, G.N, Cohen, C.
登録日1987-09-16
公開日1987-10-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (15 Å)
主引用文献Construction of an atomic model for tropomyosin and implications for interactions with actin.
J.Mol.Biol., 192, 1986
7CZD
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BU of 7czd by Molmil
Crystal structure of PD-L1 in complex with a VHH
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Programmed cell death 1 ligand 1, ...
著者Wang, C.
登録日2020-09-08
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer.
J Immunother Cancer, 9, 2021
2G4H
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BU of 2g4h by Molmil
Anomalous substructure of apoferritin
分子名称: CADMIUM ION, CHLORIDE ION, Ferritin light chain
著者Mueller-Dieckmann, C, Weiss, M.S.
登録日2006-02-22
公開日2007-03-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths.
Acta Crystallogr.,Sect.D, 63, 2007
2RCS
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BU of 2rcs by Molmil
IMMUNOGLOBULIN 48G7 GERMLINE FAB-AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
分子名称: IMMUNOGLOBULIN 48G7 GERMLINE FAB
著者Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C.
登録日1997-05-14
公開日1997-11-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
7DCS
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Crystal structure of HSF1 DNA-binding domain in complex with 3-site HSE DNA (23 bp)
分子名称: DNA (5'-D(*AP*TP*CP*CP*GP*CP*GP*AP*AP*TP*AP*TP*TP*CP*TP*AP*GP*AP*AP*CP*GP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*CP*GP*TP*TP*CP*TP*AP*GP*AP*AP*TP*AP*TP*TP*CP*GP*CP*GP*GP*A)-3'), Heat shock factor protein 1, ...
著者Feng, N, Liu, W.
登録日2020-10-27
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of heat shock factor trimers bound to DNA.
Iscience, 24, 2021
7DCI
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Crystal structure of HSF2 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation
分子名称: DNA (5'-D(*GP*GP*GP*AP*AP*TP*AP*TP*TP*CP*CP*C)-3'), Heat shock factor protein 2, SODIUM ION
著者Wei, L, Wei, L.
登録日2020-10-26
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of HSF2 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation
To Be Published
5IOJ
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BU of 5ioj by Molmil
Crystal structure of the Sphingobium sp. TCM1 phosphotriesterase without the binuclear manganese center
分子名称: Haloalkylphosphorus hydrolase
著者Mabanglo, M.F, Raushel, F.M.
登録日2016-03-08
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of a Novel Phosphotriesterase from Sphingobium sp. TCM1: A Familiar Binuclear Metal Center Embedded in a Seven-Bladed beta-Propeller Protein Fold.
Biochemistry, 55, 2016
2RTU
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Solution structure of oxidized human HMGB1 A box
分子名称: High mobility group protein B1
著者Jing, W, Tochio, N, Tate, S.
登録日2013-09-12
公開日2014-03-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Redox-sensitive structural change in the A-domain of HMGB1 and its implication for the binding to cisplatin modified DNA.
Biochem.Biophys.Res.Commun., 441, 2013
2RLI
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BU of 2rli by Molmil
Solution structure of Cu(I) human Sco2
分子名称: COPPER (I) ION, SCO2 protein homolog, mitochondrial
著者Banci, L, Bertini, I, Ciofi-baffoni, S, Gerothanassis, I.P, Leontari, I, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE), Structural Proteomics in Europe 2 (SPINE-2)
登録日2007-07-11
公開日2007-08-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A Structural Characterization of Human SCO2
Structure, 15, 2007
2RVM
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BU of 2rvm by Molmil
Solution structure of the chromodomain of HP1alpha with the phosphorylated N-terminal tail
分子名称: Chromobox protein homolog 5
著者Kawaguchi, A, Nishimura, Y.
登録日2015-12-18
公開日2016-03-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2RO9
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Solution structure of calcium bound soybean calmodulin isoform 1 C-terminal domain
分子名称: CALCIUM ION, Calmodulin-2
著者Ishida, H, Huang, H, Yamniuk, A.P, Takaya, Y, Vogel, H.J.
登録日2008-03-14
公開日2008-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structures of two soybean calmodulin isoforms provide a structural basis for their selective target activation properties
J.Biol.Chem., 283, 2008
2G6K
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BU of 2g6k by Molmil
Structure of rat nNOS heme domain (BH4 bound) complexed with NO
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ARGININE, ...
著者Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L.
登録日2006-02-24
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
2ROO
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BU of 2roo by Molmil
Solution structure of Magi4, a spider toxin from Macrothele gigas
分子名称: Neurotoxin magi-4
著者Yamaji, N.
登録日2008-04-04
公開日2009-04-07
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Chemical synthesis and solution structure of a spider toxin that affects the inactivation of mammalian sodium channels
To be Published
5I3B
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BU of 5i3b by Molmil
Crystal Structure of tyrosinase from Bacillus megaterium with configuration B of hydroquinone inhibitor in the active site
分子名称: Tyrosinase, ZINC ION, benzene-1,4-diol
著者Kanteev, M, Deri, B, Adir, N, Fishman, A.
登録日2016-02-10
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The unravelling of the complex pattern of tyrosinase inhibition.
Sci Rep, 6, 2016
2REN
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BU of 2ren by Molmil
STRUCTURE OF RECOMBINANT HUMAN RENIN, A TARGET FOR CARDIOVASCULAR-ACTIVE DRUGS, AT 2.5 ANGSTROMS RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, RENIN
著者Sielecki, A.R, James, M.N.G.
登録日1992-02-05
公開日1994-01-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution.
Science, 243, 1989
2G86
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BU of 2g86 by Molmil
L. casei thymidylate synthase Y261F in complex with substrate, dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase
著者Finer-Moore, J.S, Stroud, R.M.
登録日2006-03-01
公開日2006-03-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261
Biochemistry, 45, 2006
2ROZ
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Structure of the C-terminal PID Domain of Fe65L1 Complexed with the Cytoplasmic Tail of APP Reveals a Novel Peptide Binding Mode
分子名称: Amyloid beta A4 precursor protein-binding family B member 2, peptide from Amyloid beta A4 protein
著者Li, H, Koshiba, S, Tochio, N, Watanabe, S, Harada, T, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-25
公開日2008-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode
J.Biol.Chem., 283, 2008
2G8D
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Lactobacillus casei thymidylate synthase Y261W-dUMP complex
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, thymidylate synthase
著者Finer-Moore, J.S, Stroud, R.M.
登録日2006-03-02
公開日2006-03-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261
Biochemistry, 45, 2006
2RPP
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BU of 2rpp by Molmil
Solution structure of Tandem zinc finger domain 12 in Muscleblind-like protein 2
分子名称: Muscleblind-like protein 2, ZINC ION
著者Abe, C, Dang, W, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-06-24
公開日2009-05-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the RNA binding domain in the human muscleblind-like protein 2
Protein Sci., 18, 2009
2G89
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L. casei thymidylate synthase Y261A in complex with substrate, dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, thymidylate synthase
著者Finer-Moore, J.S, Stroud, R.M.
登録日2006-03-02
公開日2006-03-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261
Biochemistry, 45, 2006
2RQ5
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BU of 2rq5 by Molmil
Solution structure of the AT-rich interaction domain (ARID) of Jumonji/JARID2
分子名称: Protein Jumonji
著者Kusunoki, H, Kohno, T.
登録日2009-02-06
公開日2009-06-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the AT-rich interaction domain of Jumonji/JARID2
Proteins, 76, 2009
2RQK
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NMR Solution Structure of Mesoderm Development (MESD) - closed conformation
分子名称: Mesoderm development candidate 2
著者Koehler, C, Lighthouse, J.K, Werther, T, Andersen, O.M, Diehl, A, Schmieder, P, Holdener, B.C, Oschkinat, H.
登録日2009-08-06
公開日2009-08-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The Structure of MESD45-184 Brings Light into the Mechanism of LDLR Family Folding
Structure, 19, 2011
2RQW
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Solution structure of Bem1p SH3CI domain complexed with Ste20p-PRR peptide
分子名称: 24-meric peptide from Serine/threonine-protein kinase STE20, Bud emergence protein 1
著者Takaku, T, Ogura, K, Inagaki, F.
登録日2009-12-21
公開日2010-04-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42
J.Biol.Chem., 285, 2010
2G9L
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The High-resolution Solution Conformation of an Antimicrobial Peptide Gaegurin 4 and Its Mode of Membrane Interaction
分子名称: Gaegurin-4
著者Chi, S.-W, Han, K.-H.
登録日2006-03-06
公開日2007-01-16
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure and membrane interaction mode of an antimicrobial peptide gaegurin 4
Biochem.Biophys.Res.Commun., 352, 2007
2RT9
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Solution structure of a regulatory domain of meiosis inhibitor
分子名称: F-box only protein 43, ZINC ION
著者Shoji, S, Muto, Y, Ikeda, M, He, F, Tsuda, K, Ohsawa, N, Akasaka, R, Terada, T, Wakiyama, M, Shirouzu, M, Yokoyama, S.
登録日2013-07-05
公開日2014-07-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation
FEBS Open Bio, 4, 2014

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