1H8K
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1W12
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![BU of 1w12 by Molmil](/molmil-images/mine/1w12) | UROKINASE TYPE PLASMINOGEN ACTIVATOR | 分子名称: | N-((1S)-4-{[AMINO(IMINO)METHYL]AMINO}-1-FORMYLBUTYL)-2-{(3R)-3-[(BENZYLSULFONYL)AMINO]-2-OXO-5-PHENYL-2,3-DIHYDRO-1H-1,4-BENZODIAZEPIN-1-YL}ACETAMIDE, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | 著者 | Jacob, U. | 登録日 | 2004-06-15 | 公開日 | 2008-05-20 | 最終更新日 | 2019-05-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystals of Urokinase Type Plasminogen Activator Complexes Reveal the Binding Mode of Peptidomimetic Inhibitors. J.Mol.Biol., 328, 2003
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2DJS
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![BU of 2djs by Molmil](/molmil-images/mine/2djs) | Solution structures of the fn3 domain of human ephrin type-B receptor 1 | 分子名称: | Ephrin type-B receptor 1 | 著者 | Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-04-05 | 公開日 | 2006-10-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the fn3 domain of human ephrin type-B receptor 1 To be Published
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1W21
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![BU of 1w21 by Molmil](/molmil-images/mine/1w21) | Structure of Neuraminidase from English duck subtype N6 complexed with 30 mM sialic acid (NANA, Neu5Ac), crystal soaked for 43 hours at 291 K. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Rudino-Pinera, E, Tunnah, P, Crennell, S.J, Webster, R.G, Laver, W.G, Garman, E.F. | 登録日 | 2004-06-25 | 公開日 | 2006-01-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The Crystal Structure of Type a Influenza Virus Neuraminidase of the N6 Subtype Reveals the Existence of Two Separate Neu5Ac Binding Sites To be Published
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1W0Z
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![BU of 1w0z by Molmil](/molmil-images/mine/1w0z) | Urokinase type plasminogen activator | 分子名称: | N-(BUTYLSULFONYL)-D-SERYL-N-{4-[AMINO(IMINO)METHYL]BENZYL}-L-ALANINAMIDE, SULFATE ION, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | 著者 | Jacob, U. | 登録日 | 2004-06-15 | 公開日 | 2008-05-20 | 最終更新日 | 2019-09-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystals of urokinase type plasminogen activator complexes reveal the binding mode of peptidomimetic inhibitors. J.Mol.Biol., 328, 2003
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2DL8
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2DMP
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![BU of 2dmp by Molmil](/molmil-images/mine/2dmp) | Solution structure of the third homeobox domain of Zinc fingers and homeoboxes protein 2 | 分子名称: | Zinc fingers and homeoboxes protein 2 | 著者 | Ohnishi, S, Sasagawa, A, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-04-24 | 公開日 | 2006-10-24 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the third homeobox domain of Zinc fingers and homeoboxes protein 2 To be Published
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1HBQ
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2XK8
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![BU of 2xk8 by Molmil](/molmil-images/mine/2xk8) | Structure of Nek2 bound to aminopyrazine compound 15 | 分子名称: | 4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-methoxybenzoic acid, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 | 著者 | Mas-Droux, C, Bayliss, R. | 登録日 | 2010-07-07 | 公開日 | 2010-10-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization. J.Med.Chem., 53, 2010
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1HBY
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![BU of 1hby by Molmil](/molmil-images/mine/1hby) | Binding of Phosphate and Pyrophosphate ions at the active site of human angiogenin as revealed by X-ray Crystallography | 分子名称: | ANGIOGENIN, PHOSPHATE ION | 著者 | Leonidas, D.D, Chavali, G.B, Jardine, A.S, Li, S, Shapiro, R, Acharya, K.R. | 登録日 | 2001-04-21 | 公開日 | 2001-08-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography Protein Sci., 10, 2001
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2BD3
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![BU of 2bd3 by Molmil](/molmil-images/mine/2bd3) | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Lys-Ala-NH2 at pH 5.0 | 分子名称: | ALANINE, CALCIUM ION, Elastase-1, ... | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | 登録日 | 2005-10-20 | 公開日 | 2006-05-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural analyses on intermediates in serine protease catalysis J.Biol.Chem., 281, 2006
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1HEF
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![BU of 1hef by Molmil](/molmil-images/mine/1hef) | The crystal structures at 2.2 angstroms resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations | 分子名称: | HIV-1 PROTEASE, SKF 108738 PEPTIDE INHIBITOR | 著者 | Murthy, K, Winborne, E.L, Minnich, M.D, Culp, J.S, Debouck, C. | 登録日 | 1992-09-21 | 公開日 | 1994-05-31 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structures at 2.2-A resolution of hydroxyethylene-based inhibitors bound to human immunodeficiency virus type 1 protease show that the inhibitors are present in two distinct orientations. J.Biol.Chem., 267, 1992
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1S5S
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![BU of 1s5s by Molmil](/molmil-images/mine/1s5s) | Porcine trypsin complexed with guanidine-3-propanol inhibitor | 分子名称: | CALCIUM ION, GLYCEROL, GUANIDINE-3-PROPANOL, ... | 著者 | Transue, T.R, Krahn, J.M, Gabel, S.A, DeRose, E.F, London, R.E. | 登録日 | 2004-01-21 | 公開日 | 2004-03-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | X-ray and NMR characterization of covalent complexes of trypsin, borate, and alcohols. Biochemistry, 43, 2004
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1HBS
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1VG1
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![BU of 1vg1 by Molmil](/molmil-images/mine/1vg1) | GDP-Bound Rab7 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-7 | 著者 | Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K. | 登録日 | 2004-04-22 | 公開日 | 2004-07-20 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease Cell(Cambridge,Mass.), 117, 2004
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1VGC
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![BU of 1vgc by Molmil](/molmil-images/mine/1vgc) | GAMMA-CHYMOTRYPSIN L-PARA-CHLORO-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX | 分子名称: | GAMMA CHYMOTRYPSIN, L-1-(4-CHLOROPHENYL)-2-(ACETAMIDO)ETHANE BORONIC ACID, SULFATE ION | 著者 | Stoll, V.S, Eger, B.T, Hynes, R.C, Martichonok, V, Jones, J.B, Pai, E.F. | 登録日 | 1997-05-01 | 公開日 | 1997-11-12 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Differences in binding modes of enantiomers of 1-acetamido boronic acid based protease inhibitors: crystal structures of gamma-chymotrypsin and subtilisin Carlsberg complexes. Biochemistry, 37, 1998
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1GNN
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![BU of 1gnn by Molmil](/molmil-images/mine/1gnn) | HIV-1 PROTEASE MUTANT WITH VAL 82 REPLACED BY ASN (V82N) COMPLEXED WITH U89360E (INHIBITOR) | 分子名称: | HIV-1 PROTEASE, N-[[1-[N-ACETAMIDYL]-[1-CYCLOHEXYLMETHYL-2-HYDROXY-4-ISOPROPYL]-BUT-4-YL]-CARBONYL]-GLUTAMINYL-ARGINYL-AMIDE | 著者 | Hong, L, Treharne, A, Hartsuck, J.A, Foundling, S, Tang, J. | 登録日 | 1996-05-04 | 公開日 | 1996-11-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of complexes of a peptidic inhibitor with wild-type and two mutant HIV-1 proteases. Biochemistry, 35, 1996
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2V62
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![BU of 2v62 by Molmil](/molmil-images/mine/2v62) | Structure of vaccinia-related kinase 2 | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, SERINE/THREONINE-PROTEIN KINASE VRK2, ... | 著者 | Bunkoczi, G, Eswaran, J, Cooper, C, Fedorov, O, Keates, T, Rellos, P, Salah, E, Savitsky, P, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Weigelt, J, Knapp, S. | 登録日 | 2007-07-13 | 公開日 | 2007-08-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Pseudokinase Vrk3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site. Structure, 17, 2009
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2XK6
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![BU of 2xk6 by Molmil](/molmil-images/mine/2xk6) | Structure of Nek2 bound to aminopyrazine compound 36 | 分子名称: | CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2, cis-4-[3-amino-6-(3-cyclopropylthiophen-2-yl)pyrazin-2-yl]cyclohexanecarboxylic acid | 著者 | Mas-Droux, C, Bayliss, R. | 登録日 | 2010-07-07 | 公開日 | 2010-10-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization. J.Med.Chem., 53, 2010
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3VUL
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2BLO
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2BTS
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![BU of 2bts by Molmil](/molmil-images/mine/2bts) | STRUCTURE OF CDK2 COMPLEXED WITH PNU-230032 | 分子名称: | 4-[(5-ISOPROPYL-1,3-THIAZOL-2-YL)AMINO]BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Vulpetti, A, Casale, E, Roletto, F, Amici, R, Villa, M, Pevarello, P. | 登録日 | 2005-06-06 | 公開日 | 2005-11-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Structure-Based Drug Design to the Discovery of New 2-Aminothiazole Cdk2 Inhibitors. J.Mol.Graph.Model., 24, 2006
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2BD4
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![BU of 2bd4 by Molmil](/molmil-images/mine/2bd4) | Porcine pancreatic elastase complexed with beta-casomorphin-7 and Lys-Ser at pH 5.0 | 分子名称: | CALCIUM ION, Elastase-1, LYSINE, ... | 著者 | Liu, B, Schofield, C.J, Wilmouth, R.C. | 登録日 | 2005-10-20 | 公開日 | 2006-05-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural analyses on intermediates in serine protease catalysis J.Biol.Chem., 281, 2006
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2XNE
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![BU of 2xne by Molmil](/molmil-images/mine/2xne) | Structure of Aurora-A bound to an imidazopyrazine inhibitor | 分子名称: | 3-chloro-N-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine, SERINE/THREONINE-PROTEIN KINASE 6 | 著者 | Kosmopoulou, M, Bayliss, R. | 登録日 | 2010-08-02 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells. Bioorg. Med. Chem. Lett., 20, 2010
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1HDB
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![BU of 1hdb by Molmil](/molmil-images/mine/1hdb) | ANALYSIS OF THE CRYSTAL STRUCTURE, MOLECULAR MODELING AND INFRARED SPECTROSCOPY OF THE DISTAL BETA-HEME POCKET VALINE67(E11)-THREONINE MUTATION OF HEMOGLOBIN | 分子名称: | HEMOGLOBIN (DEOXY) BETA-V67T, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | 著者 | Pechik, I, Ji, X, Fronticelli, C, Gilliland, G.L. | 登録日 | 1995-04-14 | 公開日 | 1996-04-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic, molecular modeling, and biophysical characterization of the valine beta 67 (E11)-->threonine variant of hemoglobin. Biochemistry, 35, 1996
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