PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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1K2I	Crystal Structure of Gamma-Chymotrypsin in Complex with 7-Hydroxycoumarin 分子名称: 2,4-DIHYDROXY-TRANS CINNAMIC ACID, CHYMOTRYPSINOGEN A, SULFATE ION 著者 Ghani, U, Ng, K.K.S, Atta-ur-Rahman, Choudhary, M.I, Ullah, N, James, M.N.G. 登録日 2001-09-27 公開日 2001-12-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of gamma-chymotrypsin in complex with 7-hydroxycoumarin. J.Mol.Biol., 314, 2001
2WTV	Aurora-A Inhibitor Structure 分子名称: 1,2-ETHANEDIOL, 4-{[9-CHLORO-7-(2,6-DIFLUOROPHENYL)-5H-PYRIMIDO[5,4-D][2]BENZAZEPIN-2-YL]AMINO}BENZOIC ACID, ACETATE ION, ... 著者 Kosmopoulou, M, Bayliss, R. 登録日 2009-09-22 公開日 2010-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of an Aurora-A Mutant that Mimics Aurora-B Bound to Mln8054: Insights Into Selectivity and Drug Design. Biochem.J., 427, 2010
2C6K	Crystal structure of the human CDK2 complexed with the triazolopyrimidine inhibitor 分子名称: 4-{[5-(CYCLOHEXYLAMINO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 著者 Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. 登録日 2005-11-10 公開日 2005-12-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Triazolo[1,5-A]Pyrimidines as Novel Cdk2 Inhibitors: Protein Structure-Guided Design and Sar. Bioorg.Med.Chem.Lett., 16, 2006
1K1N	BOVINE TRYPSIN-INHIBITOR COMPLEX 分子名称: CALCIUM ION, TRYPSIN, [N-[N-(4-METHOXY-2,3,6-TRIMETHYLPHENYLSULFONYL)-L-ASPARTYL]-D-(4-AMIDINO-PHENYLALANYL)]-PIPERIDINE 著者 Stubbs, M.T. 登録日 2001-09-25 公開日 2001-11-28 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313, 2001
1X9F	Hemoglobin Dodecamer from Lumbricus Erythrocruorin 分子名称: CARBON MONOXIDE, Globin II, extracellular, ... 著者 Strand, K, Knapp, J.E, Bhyravbhatla, B, Royer Jr, W.E. 登録日 2004-08-20 公開日 2004-11-30 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of the hemoglobin dodecamer from lumbricus erythrocruorin: allosteric core of giant annelid respiratory complexes J.Mol.Biol., 344, 2004
1XAR	Crystal Structure of a fragment of DC-SIGNR (containing the carbohydrate recognition domain and two repeats of the neck). 分子名称: CD209 antigen-like protein 1, SODIUM ION 著者 Feinberg, H, Guo, Y, Mitchell, D.A, Drickamer, K, Weis, W.I. 登録日 2004-08-26 公開日 2004-11-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR J.Biol.Chem., 280, 2005
2BQD	CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 1998-05-21 公開日 1998-08-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A general rule for the relationship between hydrophobic effect and conformational stability of a protein: stability and structure of a series of hydrophobic mutants of human lysozyme. J.Mol.Biol., 280, 1998
1H6M	Covalent glycosyl-enzyme intermediate of hen egg white lysozyme 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose, LYSOZYME C, SODIUM ION 著者 Vocadlo, D.J, Davies, G.J, Laine, R, Withers, S.G. 登録日 2001-06-19 公開日 2001-08-30 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Catalysis by Hen Egg-White Lysozyme Proceeds Via a Covalent Intermediate Nature, 412, 2001
3G90	JNK-3 bound to (Z)-5-fluoro-1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)indolin-2-one 分子名称: (3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime, Mitogen-activated protein kinase 10 著者 Xie, X, Jacobs, M.D. 登録日 2009-02-12 公開日 2009-02-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design and parallel synthesis of N-benzyl isatin oximes as JNK3 MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
1HCL	HUMAN CYCLIN-DEPENDENT KINASE 2 分子名称: HUMAN CYCLIN-DEPENDENT KINASE 2 著者 Schulze-Gahmen, U, De Bondt, H.L, Kim, S.-H. 登録日 1996-06-03 公開日 1996-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J.Med.Chem., 39, 1996
2BLJ	Structure of L29W MbCO 分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE 著者 Nienhaus, K, Ostermann, A, Nienhaus, G.U, Parak, F.G, Schmidt, M. 登録日 2005-03-04 公開日 2005-04-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ligand Migration and Protein Fluctuations in Myoglobin Mutant L29W Biochemistry, 44, 2005
1HAQ	FOUR MODELS OF HUMAN FACTOR H DETERMINED BY SOLUTION SCATTERING CURVE-FITTING AND HOMOLOGY MODELLING 分子名称: COMPLEMENT FACTOR H 著者 Aslam, M, Perkins, S.J. 登録日 2001-04-06 公開日 2002-04-05 最終更新日 2024-05-08 実験手法 SOLUTION SCATTERING 主引用文献 Folded-Back Solution Structure of Monomeric Factor H of Human Complement by Synchrotron X-Ray and Neutron Scattering, Analytical Ultracentrifugation and Constrained Molecular Modelling. J.Mol.Biol., 309, 2001
1XCM	Crystal structure of the GppNHp-bound H-Ras G60A mutant 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Transforming protein p21/H-Ras-1 著者 Ford, B, Nassar, N. 登録日 2004-09-02 公開日 2005-05-10 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystal structure of the GppNHp-bound form of the RasG60A mutant To be Published
1XDH	Structure of plasmepsin II in complex with pepstatin A 分子名称: Pepstatin, Plasmepsin 2 著者 Prade, L. 登録日 2004-09-06 公開日 2005-08-23 最終更新日 2013-02-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of plasmepsin II in complex with pepstatin A To be published
2BLQ	Elastase After A High Dose X-Ray "Burn" 分子名称: CALCIUM ION, ELASTASE 1, SULFATE ION 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-08 公開日 2005-09-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
1HEP	STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 分子名称: HEN EGG WHITE LYSOZYME 著者 Wilson, K.P, Malcolm, B.A, Matthews, B.W. 登録日 1992-01-10 公開日 1993-10-31 最終更新日 2021-06-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme. J.Biol.Chem., 267, 1992
1XDA	STRUCTURE OF INSULIN 分子名称: CHLORIDE ION, FATTY ACID ACYLATED INSULIN, MYRISTIC ACID, ... 著者 Whittingham, J.L, Havelund, S, Jonassen, I. 登録日 1996-12-18 公開日 1997-07-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a prolonged-acting insulin with albumin-binding properties. Biochemistry, 36, 1997
1HFG	NMR solution structure of vMIP-II 1-71 from Kaposi's sarcoma-associated herpesvirus (minimized average structure). 分子名称: VIRAL MACROPHAGE INFLAMMATORY PROTEIN-II 著者 Crump, M.P, Elisseeva, E, Gong, J.-H, Clark-Lewis, I, Sykes, B.D. 登録日 2000-12-01 公開日 2001-01-07 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Structure/Function of Human Herpesvirus-8 Mip-II (1-71) and the Antagonist N-Terminal Segment (1-10) FEBS Lett., 489, 2001
2X8E	Discovery of a Novel Class of triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration 分子名称: 5-METHYL-8-PYRIDIN-4-YL[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1(2H)-ONE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION 著者 Read, J.A, Breed, J, Haye, H, McCall, E, Rowsell, S, Vallentine, A, White, A. 登録日 2010-03-09 公開日 2010-08-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors-Hit to Lead Exploration. Bioorg.Med.Chem., 20, 2010
1XFE	Solution structure of the LA7-EGFA pair from the LDL receptor 分子名称: CALCIUM ION, Low-density lipoprotein receptor 著者 Beglova, N, Jeon, H, Fisher, C, Blacklow, S.C. 登録日 2004-09-14 公開日 2004-11-02 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Cooperation between Fixed and Low pH-Inducible Interfaces Controls Lipoprotein Release by the LDL Receptor Mol.Cell, 16, 2004
2BQL	CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Yamagata, Y, Yutani, K. 登録日 1998-05-21 公開日 1998-08-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A general rule for the relationship between hydrophobic effect and conformational stability of a protein: stability and structure of a series of hydrophobic mutants of human lysozyme. J.Mol.Biol., 280, 1998
1GWD	Tri-iodide derivative of hen egg-white lysozyme 分子名称: 1,2-ETHANEDIOL, CARBON MONOXIDE, CHLORIDE ION, ... 著者 Evans, G, Bricogne, G. 登録日 2002-03-14 公開日 2002-06-06 最終更新日 2017-06-28 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Triiodide Derivatization and Combinatorial Counter-Ion Replacement: Two Methods for Enhancing Phasing Signal Using Laboratory Cu Kalpha X-Ray Equipment Acta Crystallogr.,Sect.D, 58, 2002
1TAL	ALPHA-LYTIC PROTEASE AT 120 K (SINGLE STRUCTURE MODEL) 分子名称: ALPHA-LYTIC PROTEASE, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE 著者 Rader, S.D, Agard, D.A. 登録日 1996-10-30 公開日 1997-04-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conformational substates in enzyme mechanism: the 120 K structure of alpha-lytic protease at 1.5 A resolution. Protein Sci., 6, 1997
1GXV	Solution structure of lysozyme at low and high pressure 分子名称: LYSOZYME C 著者 Refaee, M, Akasaka, K, Williamson, M. 登録日 2002-04-12 公開日 2003-03-27 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Pressure-Dependent Changes in the Solution Structure of Hen Egg-White Lysozyme J.Mol.Biol., 327, 2003
1GTG	Crystal structure of the thermostable serine-carboxyl type proteinase, kumamolysin (kscp) 分子名称: CALCIUM ION, KUMAMOLYSIN 著者 Comellas-Bigler, M, Fuentes-Prior, P, Maskos, K, Huber, R, Oyama, H, Uchida, K, Dunn, B.M, Oda, K, Bode, W. 登録日 2002-01-15 公開日 2002-06-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The 1.4 A Crystal Structure of Kumamolysin. A Thermostable Serine-Carboxyl-Type Proteinase Structure, 10, 2002

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