9OB9
 
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9OAK
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9OAN
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9OBC
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4X23
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5OMX
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6G0L
 | | Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | | 著者 | Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. | | 登録日 | 2018-03-19 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome.
Elife, 7, 2018
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5ONG
 | | X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer | | 分子名称: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | | 著者 | Frouws, T.D, Barth, P.D, Richmond, T.J. | | 登録日 | 2017-08-03 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.797 Å) | | 主引用文献 | Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
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1ID3
 | | CRYSTAL STRUCTURE OF THE YEAST NUCLEOSOME CORE PARTICLE REVEALS FUNDAMENTAL DIFFERENCES IN INTER-NUCLEOSOME INTERACTIONS | | 分子名称: | HISTONE H2A.1, HISTONE H2B.2, HISTONE H3, ... | | 著者 | White, C.L, Suto, R.K, Luger, K. | | 登録日 | 2001-04-03 | | 公開日 | 2001-09-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions.
EMBO J., 20, 2001
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5ONW
 | | X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer and the two H2A/H2B dimers crosslinked via H2A N38C | | 分子名称: | CHLORIDE ION, DNA (147-MER), Histone H2A, ... | | 著者 | Frouws, T.D, Barth, P.D, Richmond, T.J. | | 登録日 | 2017-08-04 | | 公開日 | 2017-11-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
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4S0M
 | | Crystal Structure of nucleoside diphosphate kinase at 1.92 A resolution from acinetobacter baumannii | | 分子名称: | MAGNESIUM ION, Nucleoside diphosphate kinase | | 著者 | Sikarwar, J, Shukla, P.K, Kaur, P, Sharma, S, Singh, T.P. | | 登録日 | 2015-01-02 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.922 Å) | | 主引用文献 | Crystal Structure of nucleoside diphosphate kinase at 1.92 A resolution from Acinetobacter baumannii
To be Published
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3RDP
 | | Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with N-METHYL-FHBT | | 分子名称: | 6-[(2R)-2-(fluoromethyl)-3-hydroxy-propyl]-1,5-dimethyl-pyrimidine-2,4-dione, SULFATE ION, Thymidine kinase | | 著者 | Pernot, L, Perozzo, R, Westermaier, Y, Martic, M, Ametamey, S, Scapozza, L. | | 登録日 | 2011-04-01 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo.
Nucleosides Nucleotides Nucleic Acids, 30, 2011
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4LDN
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9OD6
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9O9R
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9NLP
 | | HIV-1 Reverse Transcriptase with New Non-Nucleoside Reverse Transcriptase Inhibitor 12126065 | | 分子名称: | 4-({5-amino-1-[6-(2-cyanoethyl)naphthalene-1-sulfonyl]-1H-1,2,4-triazol-3-yl}amino)-2-chlorobenzonitrile, Reverse transcriptase p51 subunit, Reverse transcriptase p66 subunit | | 著者 | Young, M.A, Lane, T.R, Raman, R, Nelson, J.A.E, Riabova, O, Kazakova, E, Monakhova, N, Tsedilin, A, Rees, S.D, Quinnell, D, Chang, G, Ekins, S. | | 登録日 | 2025-03-03 | | 公開日 | 2025-05-07 | | 最終更新日 | 2025-05-21 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Cryo-EM Structure of HIV-1 Reverse Transcriptase with N -Phenyl-1-(phenylsulfonyl)-1 H -1,2,4-triazol-3-amine: A New HIV-1 Non-nucleoside Inhibitor.
Acs Infect Dis., 11, 2025
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9RSA
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6G7X
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6FTX
 | | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin-remodeling ATPase, ... | | 著者 | Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. | | 登録日 | 2018-02-25 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome.
Elife, 7, 2018
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4RAQ
 | | Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their pro-drugs as antimalarial agents | | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, [(2-{[2-(6-oxo-1,6-dihydro-9H-purin-9-yl)ethyl](2-phosphonoethyl)amino}ethoxy)methyl]phosphonic acid | | 著者 | Keough, D.T, Hockova, D, Janeba, Z, Wang, T.-H, Naesens, L, Edstein, M.D, Chavchich, M, Guddat, L.W. | | 登録日 | 2014-09-10 | | 公開日 | 2015-01-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents.
J.Med.Chem., 58, 2015
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6LMU
 | | Cryo-EM structure of the human CALHM2 | | 分子名称: | Calcium homeostasis modulator protein 2 | | 著者 | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | | 登録日 | 2019-12-26 | | 公開日 | 2020-07-29 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies.
Sci Adv, 6, 2020
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4RAD
 | | Aza-acyclic nucleoside phosphonates containing a second phosphonate group as inhibitors of the human, Plasmodium falciparum and vivax 6-oxopurine phosphoribosyltransferases and their pro-drugs as antimalarial agents | | 分子名称: | (2-{[2-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)ethyl][2-(2-phosphonoethoxy)ethyl]amino}ethyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | | 著者 | Keough, D.T, Hockova, D, Janeba, Z, Wang, T.-H, Naesens, L, Edstein, M.D, Chavchich, M, Guddat, L.W. | | 登録日 | 2014-09-10 | | 公開日 | 2015-01-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents.
J.Med.Chem., 58, 2015
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6USJ
 | | Structure of two nucleosomes bridged by human PARP2 | | 分子名称: | Histone H2A, Histone H2B type 1-J, Histone H3.1, ... | | 著者 | Gaullier, G, Bowerman, S, Luger, K. | | 登録日 | 2019-10-27 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (10.5 Å) | | 主引用文献 | Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1.
Plos One, 15, 2020
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4RJ2
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4WR2
 | | Crystal structure of a putative pyrimidine-specific ribonucleoside hydrolase (RihA) Protein from Shewanella loihica PV-4 (SHEW_0697, Target PSI-029635) with divalent cation and PEG 400 bound at the active site | | 分子名称: | CALCIUM ION, PENTAETHYLENE GLYCOL, Pyrimidine-specific ribonucleoside hydrolase RihA | | 著者 | Himmel, D.M, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Seidel, R.D, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2014-10-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a putative pyrimidine-specific ribonucleoside hydrolase (RihA) Protein from Shewanella loihica PV-4 (SHEW_0697, Target PSI-029635) with divalent cation and PEG 400 bound at the active site
To be published
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