9CPD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9cpd by Molmil](/molmil-images/mine/9cpd) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | 分子名称: | 4-[(3-methoxyphenyl)amino]-2-methylquinoline-6-carboximidamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | 登録日 | 2024-07-18 | 公開日 | 2024-08-07 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1. Bioorg.Med.Chem.Lett., 2024
|
|
1DEL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1del by Molmil](/molmil-images/mine/1del) | |
1H6V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1h6v by Molmil](/molmil-images/mine/1h6v) | Mammalian thioredoxin reductase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, THIOREDOXIN REDUCTASE | 著者 | Sandalova, T, Zhong, L, Lindqvist, Y, Holmgren, A, Schneider, G. | 登録日 | 2001-06-27 | 公開日 | 2001-08-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Three-Dimensional Structure of a Mammalian Thioredoxin Reductase: Implication for Mechanism and Evolution of a Selenocysteine Dependent Enzyme Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
9CPJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9cpj by Molmil](/molmil-images/mine/9cpj) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | 分子名称: | RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | 登録日 | 2024-07-18 | 公開日 | 2024-08-07 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1. Bioorg.Med.Chem.Lett., 2024
|
|
9CPG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9cpg by Molmil](/molmil-images/mine/9cpg) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | 分子名称: | 4-carbamimidamidophenyl 4-carbamimidamidobenzoate, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | 登録日 | 2024-07-18 | 公開日 | 2024-08-07 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1. Bioorg.Med.Chem.Lett., 2024
|
|
9CPI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9cpi by Molmil](/molmil-images/mine/9cpi) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | 分子名称: | 4-[1-(2-aminoethyl)-4,5-dihydro-1H-imidazol-2-yl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]benzamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | 登録日 | 2024-07-18 | 公開日 | 2024-08-07 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1. Bioorg.Med.Chem.Lett., 2024
|
|
3SGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sgb by Molmil](/molmil-images/mine/3sgb) | STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION | 分子名称: | PROTEINASE B (SGPB), TURKEY OVOMUCOID INHIBITOR (OMTKY3) | 著者 | Read, R.J, Fujinaga, M, Sielecki, A.R, James, M.N.G. | 登録日 | 1983-01-21 | 公開日 | 1983-07-12 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution. Biochemistry, 22, 1983
|
|
4NKC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nkc by Molmil](/molmil-images/mine/4nkc) | |
3QDA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qda by Molmil](/molmil-images/mine/3qda) | |
1S5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s5j by Molmil](/molmil-images/mine/1s5j) | Insight in DNA Replication: The crystal structure of DNA Polymerase B1 from the archaeon Sulfolobus solfataricus | 分子名称: | DNA polymerase I, MAGNESIUM ION, SULFATE ION | 著者 | Savino, C, Federici, L, Nastopoulos, V, Johnson, K.A, Pisani, F.M, Rossi, M, Tsernoglou, D. | 登録日 | 2004-01-21 | 公開日 | 2004-11-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus Structure, 12, 2004
|
|
1CSQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1csq by Molmil](/molmil-images/mine/1csq) | |
2VC5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vc5 by Molmil](/molmil-images/mine/2vc5) | Structural basis for natural lactonase and promiscuous phosphotriesterase activities | 分子名称: | 1,2-ETHANEDIOL, ARYLDIALKYLPHOSPHATASE, COBALT (II) ION, ... | 著者 | Elias, M, Dupuy, J, Merone, L, Mandrich, L, Moniot, S, Lecomte, C, Rossi, M, Masson, P, Manco, G, Chabriere, E. | 登録日 | 2007-09-18 | 公開日 | 2008-04-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities. J.Mol.Biol., 379, 2008
|
|
1YGW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ygw by Molmil](/molmil-images/mine/1ygw) | |
1BS1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bs1 by Molmil](/molmil-images/mine/1bs1) | DETHIOBIOTIN SYNTHETASE COMPLEXED WITH DETHIOBIOTIN, ADP , INORGANIC PHOSPHATE AND MAGNESIUM | 分子名称: | 8-AMINO-7-CARBOXYAMINO-NONANOIC ACID WITH ALUMINUM FLUORIDE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Kaeck, H, Sandmark, J, Gibson, K.J, Schneider, G, Lindqvist, Y. | 登録日 | 1998-08-31 | 公開日 | 1999-01-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis. Protein Sci., 7, 1998
|
|
1U0B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u0b by Molmil](/molmil-images/mine/1u0b) | Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys | 分子名称: | Cysteine--tRNA ligase, ZINC ION, cysteinyl tRNA | 著者 | Hauenstein, S, Zhang, C.M, Hou, Y.M, Perona, J.J. | 登録日 | 2004-07-13 | 公開日 | 2004-11-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Shape-selective RNA recognition by cysteinyl-tRNA synthetase Nat.Struct.Mol.Biol., 11, 2004
|
|
1CYD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cyd by Molmil](/molmil-images/mine/1cyd) | CARBONYL REDUCTASE COMPLEXED WITH NADPH AND 2-PROPANOL | 分子名称: | CARBONYL REDUCTASE, ISOPROPYL ALCOHOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Tanaka, N, Nonaka, T, Mitsui, Y. | 登録日 | 1995-09-01 | 公開日 | 1996-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family. Structure, 4, 1996
|
|
1CVW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1cvw by Molmil](/molmil-images/mine/1cvw) | Crystal structure of active site-inhibited human coagulation factor VIIA (DES-GLA) | 分子名称: | CALCIUM ION, COAGULATION FACTOR VIIA (HEAVY CHAIN) (DES-GLA), COAGULATION FACTOR VIIA (LIGHT CHAIN) (DES-GLA), ... | 著者 | Kemball-Cook, G, Johnson, D.J.D, Tuddenham, E.G.D, Harlos, K. | 登録日 | 1999-08-24 | 公開日 | 1999-08-31 | 最終更新日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Crystal structure of active site-inhibited human coagulation factor VIIa (des-Gla). J.Struct.Biol., 127, 1999
|
|
4NAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nae by Molmil](/molmil-images/mine/4nae) | PcrB from Geobacillus kaustophilus, with bound G1P | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Heptaprenylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE | 著者 | Peterhoff, D, Beer, B, Rajendran, C, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. | 登録日 | 2013-10-22 | 公開日 | 2014-06-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
|
|
1RL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rl9 by Molmil](/molmil-images/mine/1rl9) | Crystal structure of Creatine-ADP arginine kinase ternary complex | 分子名称: | (DIAMINOMETHYL-METHYL-AMINO)-ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, ... | 著者 | Azzi, A, Clark, S.A, Ellington, R.W, Chapman, M.S. | 登録日 | 2003-11-25 | 公開日 | 2004-05-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The role of phosphagen specificity loops in arginine kinase. Protein Sci., 13, 2004
|
|
1X6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x6u by Molmil](/molmil-images/mine/1x6u) | KDO8P synthase in it's binary complex with the product KDO8P | 分子名称: | 2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-8-O-phosphono-alpha-D-manno-oct-2-ulopyranosonic acid | 著者 | Vainer, R, Belakhov, V, Rabkin, E, Baasov, T, Adir, N. | 登録日 | 2004-08-12 | 公開日 | 2005-07-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Escherichia coli KDO8P Synthase Complexes Reveal the Source of Catalytic Irreversibility J.Mol.Biol., 351, 2005
|
|
1KQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kqu by Molmil](/molmil-images/mine/1kqu) | Human phospholipase A2 complexed with a substrate anologue | 分子名称: | 6-PHENYL-4(R)-(7-PHENYL-HEPTANOYLAMINO)-HEXANOIC ACID, CALCIUM ION, Phospholipase A2, ... | 著者 | Tyndall, J.D, Martin, J.L. | 登録日 | 2002-01-07 | 公開日 | 2003-11-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity. Chembiochem, 4, 2003
|
|
2W5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w5b by Molmil](/molmil-images/mine/2w5b) | Human Nek2 kinase ATPgammaS-bound | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Bayliss, R. | 登録日 | 2008-12-08 | 公開日 | 2008-12-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Insights Into the Conformational Variability and Regulation of Human Nek2 Kinase. J.Mol.Biol., 386, 2009
|
|
1TVP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tvp by Molmil](/molmil-images/mine/1tvp) | |
1TVN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tvn by Molmil](/molmil-images/mine/1tvn) | |
2BAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bai by Molmil](/molmil-images/mine/2bai) | The Zinc finger domain of Mengovirus Leader polypeptide | 分子名称: | Genome polyprotein, ZINC ION | 著者 | Cornilescu, C.C, Porter, F.W, Qin, Z, Lee, M.S, Palmenberg, A.C, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2005-10-14 | 公開日 | 2006-01-24 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the mengovirus Leader protein zinc-finger domain. Febs Lett., 582, 2008
|
|