PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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8B6L	Subtomogram average of the human Sec61-TRAP-OSTA-translocon 分子名称: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ... 著者 Gemmer, M, Fedry, J.M.M, Forster, F.G. 登録日 2022-09-27 公開日 2022-12-07 最終更新日 2023-02-08 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Visualization of translation and protein biogenesis at the ER membrane. Nature, 614, 2023
7ZL3	Signal peptide mimicry primes Sec61 for client-selective inhibition 分子名称: Cyclic depsipeptide signal peptide mimic, Protein transport protein Sec61 subunit alpha, Protein transport protein Sec61 subunit beta, ... 著者 Rehan, S, Paavilainen O, V. 登録日 2022-04-13 公開日 2023-03-22 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Signal peptide mimicry primes Sec61 for client-selective inhibition. Nat.Chem.Biol., 19, 2023
6FTI	Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome 分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Braunger, K, Becker, T, Beckmann, R. 登録日 2018-02-22 公開日 2018-03-21 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
6W6L	Cryo-EM structure of the human ribosome-TMCO1 translocon 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Keenan, R.J, McGilvray, P.T. 登録日 2020-03-17 公開日 2020-09-02 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 An ER translocon for multi-pass membrane protein biogenesis. Elife, 9, 2020
5J88	Structure of the E coli 70S ribosome with the U1060A mutation in 16S rRNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... 著者 Cocozaki, A, Ferguson, A. 登録日 2016-04-07 公開日 2016-07-06 最終更新日 2016-12-07 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
5OT7	Elongation factor G-ribosome complex captures in the absence of inhibitors. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Mace, K, Giudice, E, Chat, S, Gillet, R. 登録日 2017-08-21 公開日 2018-02-14 最終更新日 2018-04-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors. Nucleic Acids Res., 46, 2018
5J3C	Thermus thermophilus 70S termination complex containing E. coli RF1 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Hoffer, E.D, Dunham, C.M. 登録日 2016-03-30 公開日 2016-10-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
3CCQ	Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U 分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... 著者 Blaha, G, Gurel, G. 登録日 2008-02-26 公開日 2008-05-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
3CD6	Co-cystal of large Ribosomal Subunit mutant G2616A with CC-Puromycin 分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... 著者 Blaha, G, Gurel, G. 登録日 2008-02-26 公開日 2008-05-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Mutations outside the anisomycin-binding site can make ribosomes drug-resistant. J.Mol.Biol., 379, 2008
5AN9	Mechanism of eIF6 release from the nascent 60S ribosomal subunit 分子名称: 26S RIBOSOMAL RNA, 60S ACIDIC RIBOSOMAL PROTEIN P0, 60S RIBOSOMAL PROTEIN L10, ... 著者 Weis, F, Giudice, E, Churcher, M, Jin, L, Hilcenko, C, Wong, C.C, Traynor, D, Kay, R.R, Warren, A.J. 登録日 2015-09-06 公開日 2015-10-21 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanism of Eif6 Release from the Nascent 60S Ribosomal Subunit Nat.Struct.Mol.Biol., 22, 2015
5APN	Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V. 登録日 2015-09-17 公開日 2015-12-16 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell, 164, 2015
5GAE	RNC in complex with a translocating SecYEG 分子名称: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... 著者 Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. 登録日 2015-11-25 公開日 2016-01-27 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
9BDP	80S ribosome bound with angiogenin and complex of eEF1A and Ala-tRNAAla 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Loveland, A.B, Korostelev, A.A. 登録日 2024-04-12 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural mechanism of angiogenin activation by the ribosome. Nature, 630, 2024
8Y39	cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 5S ribosomal RNA, ... 著者 Li, Y, Lu, G, Li, J, Pei, X, Lin, J. 登録日 2024-01-28 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Synthetic macrolides overcoming MLS B K-resistant pathogens. Cell Discov, 10, 2024
9BDL	80S ribosome with angiogenin 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Loveland, A.B, Korostelev, A.A. 登録日 2024-04-12 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural mechanism of angiogenin activation by the ribosome. Nature, 630, 2024
9FBV	70S Escherichia coli ribosome with P-site initiatior tRNA. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ... 著者 Koller, T.O, Wilson, D.N. 登録日 2024-05-14 公開日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis. Biorxiv, 2024
5XTI	Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2 分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... 著者 Gu, J, Wu, M, Yang, M. 登録日 2017-06-19 公開日 2017-09-13 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (17.4 Å) 主引用文献 Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
5X8P	Structure of the 70S chloroplast ribosome from spinach 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Ahmed, T, Shi, J, Bhushan, S. 登録日 2017-03-03 公開日 2017-06-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation Nucleic Acids Res., 45, 2017
5XTB	Cryo-EM structure of human respiratory complex I matrix arm 分子名称: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Gu, J, Wu, M, Yang, M. 登録日 2017-06-18 公開日 2017-08-30 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
5X8T	Structure of the 50S large subunit of chloroplast ribosome from spinach 分子名称: 23S rRNA, 4.8S rRNA, 50S ribosomal protein L13, ... 著者 Ahmed, T, Shi, J, Bhushan, S. 登録日 2017-03-03 公開日 2017-06-07 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation Nucleic Acids Res., 45, 2017
6FKR	Crystal structure of the dolphin proline-rich antimicrobial peptide Tur1A bound to the Thermus thermophilus 70S ribosome 分子名称: 16 ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Mardirossian, M, Perebaskine, N, Benincasa, M, Gambato, S, Hofmann, S, Huter, P, Muller, C, Hilpert, K, Innis, C.A, Tossi, A, Wilson, D.N. 登録日 2018-01-24 公開日 2018-03-28 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome. Cell Chem Biol, 25, 2018
5XTD	Cryo-EM structure of human respiratory complex I 分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Acyl carrier protein, ... 著者 Gu, J, Wu, M, Yang, M. 登録日 2017-06-19 公開日 2017-08-30 最終更新日 2019-11-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2. Cell, 170, 2017
6G2J	Mouse mitochondrial complex I in the active state 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Agip, A.N.A, Blaza, J.N, Bridges, H.R, Viscomi, C, Rawson, S, Muench, S.P, Hirst, J. 登録日 2018-03-23 公開日 2018-06-06 最終更新日 2021-06-02 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states. Nat. Struct. Mol. Biol., 25, 2018
6GBZ	50S ribosomal subunit assembly intermediate state 5 分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. 登録日 2018-04-16 公開日 2018-06-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution. Mol. Cell, 70, 2018
4V63	Structural basis for translation termination on the 70S ribosome. 分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ... 著者 Laurberg, M, Asahara, H, Korostelev, A, Zhu, J, Trakhanov, S, Noller, H.F. 登録日 2008-05-16 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.207 Å) 主引用文献 Structural basis for translation termination on the 70S ribosome Nature, 454, 2008

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