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3GOK
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Binding site mapping of protein ligands
分子名称: 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP kinase-activated protein kinase 2
著者Scheich, C.
登録日2009-03-19
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Binding site mapping of protein ligands
To be published
1WDX
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Yeast BBC1 SH3 domain, triclinic crystal form
分子名称: Myosin tail region-interacting protein MTI1
著者Wilmanns, M, Consani Textor, L, Kursula, P, Kursula, I, Lehmann, F, Song, Y.H.
登録日2004-05-19
公開日2005-05-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of Yeast BBC1 SH3 domain, triclinic crystal form
To be Published
1J41
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Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe) hemoglobin (laser photolysed)
分子名称: BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ...
著者Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-02-21
公開日2003-07-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Direct observation of photolysis-induced tertiary structural changes in hemoglobin
Proc.Natl.Acad.Sci.USA, 100, 2003
2QR7
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2.0A X-ray structure of C-terminal kinase domain of p90 ribosomal S6 kinase 2: Se-Met derivative
分子名称: Ribosomal protein S6 kinase alpha-3, SODIUM ION
著者Malakhova, M, Tereshko, V, Dong, Z.
登録日2007-07-27
公開日2007-12-11
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2.
Nat.Struct.Mol.Biol., 15, 2008
1X48
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Solution structure of the second DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase
分子名称: Interferon-induced, double-stranded RNA-activated protein kinase
著者He, F, Muto, Y, Inoue, M, Tarada, T, Shirouzu, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-14
公開日2005-11-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the second DSRM domain in Interferon-induced, double-stranded RNA-activated protein kinase
To be Published
1IR7
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IM mutant of lysozyme
分子名称: lysozyme
著者Ohmura, T, Ueda, T, Hashimoto, Y, Imoto, T.
登録日2001-09-19
公開日2001-10-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tolerance of point substitution of methionine for isoleucine in hen egg white lysozyme.
Protein Eng., 14, 2001
1IR9
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IM mutant of lysozyme
分子名称: lysozyme
著者Ohmura, T, Ueda, T, Hashimoto, Y, Imoto, T.
登録日2001-09-19
公開日2001-10-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Tolerance of point substitution of methionine for isoleucine in hen egg white lysozyme.
Protein Eng., 14, 2001
1X5H
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BU of 1x5h by Molmil
The solution structure of the third fibronectin type III domain of human Neogenin
分子名称: Neogenin
著者Tochio, N, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-15
公開日2005-11-15
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the third fibronectin type III domain of human Neogenin
To be Published
1X5X
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Solution structure of the fibronectin type-III domain of human fibronectin type III domain containing protein 3
分子名称: Fibronectin type-III domain containing protein 3a
著者Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-17
公開日2005-11-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the fibronectin type-III domain of human fibronectin type III domain containing protein 3
To be Published
1IP4
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G72A HUMAN LYSOZYME
分子名称: LYSOZYME C, SODIUM ION
著者Takano, K, Yamagata, Y, Yutani, K.
登録日2001-04-20
公開日2001-11-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of amino acid residues in left-handed helical conformation for the conformational stability of a protein.
Proteins, 45, 2001
1IRV
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CYTOCHROME C ISOZYME 1, REDUCED, MUTANT WITH ILE 75 REPLACED BY MET AND CYS 102 REPLACED BY THR
分子名称: CYTOCHROME C, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Berghuis, A.M, Brayer, G.D.
登録日1996-06-27
公開日1997-01-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic and structural contributions of critical surface and internal residues to cytochrome c electron transfer reactivity.
Biochemistry, 35, 1996
1WBO
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fragment based p38 inhibitors
分子名称: 2-CHLOROPHENOL, MITOGEN-ACTIVATED PROTEIN KINASE 14
著者Cleasby, A, Devine, L, Gill, A, Jhoti, H.
登録日2004-11-04
公開日2005-01-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Fragment-Based Lead Discovery Using X-Ray Crystallography
J.Med.Chem., 48, 2005
1WBW
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Identification of novel p38 alpha MAP Kinase inhibitors using fragment-based lead generation.
分子名称: 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE, MITOGEN-ACTIVATED PROTEIN KINASE 14
著者Tickle, J, Cleasby, A, Devine, L.A, Jhoti, H.
登録日2004-11-05
公開日2005-11-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Identification of Novel P38Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation
J.Med.Chem., 48, 2005
1IRH
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The Solution Structure of The Third Kunitz Domain of Tissue Factor Pathway Inhibitor
分子名称: tissue factor pathway inhibitor
著者Mine, S, Yamazaki, T, Miyata, T, Hara, S, Kato, H.
登録日2001-10-02
公開日2002-02-06
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitor.
Biochemistry, 41, 2002
1IS0
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Crystal Structure of a Complex of the Src SH2 Domain with Conformationally Constrained Peptide Inhibitor
分子名称: AY0 GLU GLU ILE peptide, Tyrosine-protein kinase transforming protein SRC
著者Davidson, J.P, Lubman, O, Rose, T, Waksman, G, Martin, S.F.
登録日2001-11-02
公開日2002-02-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding.
J.Am.Chem.Soc., 124, 2002
2BLP
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RNase before unattenuated X-RAY burn
分子名称: CHLORIDE ION, RIBONUCLEASE PANCREATIC PRECURSOR
著者Nanao, M.H, Ravelli, R.B.
登録日2005-03-08
公開日2005-09-07
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Improving radiation-damage substructures for RIP.
Acta Crystallogr. D Biol. Crystallogr., 61, 2005
2BLX
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HEWL before a high dose x-ray "burn"
分子名称: LYSOZYME C, TETRAETHYLENE GLYCOL
著者Nanao, M.H, Ravelli, R.B.
登録日2005-03-08
公開日2005-09-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Improving Radiation-Damage Substructures for Rip.
Acta Crystallogr.,Sect.D, 61, 2005
1IWU
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Crystal Structure Analysis of Human lysozyme at 127K.
分子名称: CHLORIDE ION, LYSOZYME C
著者Joti, Y, Nakasako, M, Kidera, A, Go, N.
登録日2002-06-03
公開日2002-09-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Nonlinear temperature dependence of the crystal structure of lysozyme: correlation between coordinate shifts and thermal factors.
Acta Crystallogr.,Sect.D, 58, 2002
2XEZ
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Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
分子名称: 1,2-ETHANEDIOL, 6-(1H-PYRAZOL-3-YL)-3-(1H-PYRAZOL-4-YL)IMIDAZO[1,2-A]PYRAZINE, SERINE/THREONINE-PROTEIN KINASE CHK1
著者Matthews, T.P, McHardy, T, Klair, S, Boxall, K, Fisher, M, Cherry, M, Allen, C.E, Addison, G.J, Ellard, J, Aherne, G.W, Westwood, I.M, vanMontfort, R, Garrett, M.D, Reader, J.C, Collins, I.
登録日2010-05-19
公開日2010-07-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Design and Evaluation of 3,6-Di(Hetero)Aryl Imidazo[1,2-A]Pyrazines as Inhibitors of Checkpoint and Other Kinases.
Bioorg.Med.Chem.Lett., 20, 2010
2C2C
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REFINEMENT OF THE CRYSTAL STRUCTURE OF OXIDIZED RHODOSPIRILLUM RUBRUM CYTOCHROME C2
分子名称: CYTOCHROME C2, HEME C
著者Bhatia, G, Finzel, B.C, Kraut, J.
登録日1983-11-03
公開日1984-02-02
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Refinement of the Crystal Structure of Oxidized Rhodospirillum Rubrum Cytochrome C2
Thesis, 1981
1SGC
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THE 1.8 ANGSTROMS STRUCTURE OF THE COMPLEX BETWEEN CHYMOSTATIN AND STREPTOMYCES GRISEUS PROTEASE A. A MODEL FOR SERINE PROTEASE CATALYTIC TETRAHEDRAL INTERMEDIATES
分子名称: CHYMOSTATIN A, PROTEINASE A
著者Delbaere, L.T.J, Brayer, G.D.
登録日1986-04-18
公開日1986-07-14
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.8 A structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates.
J.Mol.Biol., 183, 1985
1IVC
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STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID, CALCIUM ION, ...
著者Jedrzejas, M.J, Luo, M.
登録日1994-12-12
公開日1995-03-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of aromatic inhibitors of influenza virus neuraminidase.
Biochemistry, 34, 1995
1IWX
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Crystal Structure Analysis of Human lysozyme at 161K.
分子名称: CHLORIDE ION, LYSOZYME C
著者Joti, Y, Nakasako, M, Kidera, A, Go, N.
登録日2002-06-03
公開日2002-09-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Nonlinear temperature dependence of the crystal structure of lysozyme: correlation between coordinate shifts and thermal factors.
Acta Crystallogr.,Sect.D, 58, 2002
1X3D
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Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a
分子名称: Fibronectin type-III domain containing protein 3a
著者Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-02
公開日2005-11-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a
To be Published
1X4G
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Solution structure of RRM domain in Nucleolysin TIAR
分子名称: Nucleolysin TIAR
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-14
公開日2005-11-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of RRM domain in Nucleolysin TIAR
To be Published

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