PDB: 105044 件ウェブページステータス検索Chemie searchBIRD

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5NFP	Glucocorticoid Receptor in complex with budesonide 分子名称: (1~{S},2~{S},4~{R},6~{R},8~{S},9~{S},11~{S},12~{S},13~{R})-9,13-dimethyl-11-oxidanyl-8-(2-oxidanylethanoyl)-6-propyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one, 1,2-ETHANEDIOL, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... 著者 Edman, K, Wissler, L. 登録日 2017-03-15 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases. J. Med. Chem., 60, 2017
2WDF	Termus thermophilus Sulfate thiohydrolase SoxB 分子名称: MANGANESE (II) ION, SULFUR OXIDATION PROTEIN SOXB, TERTIARY-BUTYL ALCOHOL 著者 Sauve, V, Roversi, P, Leath, K.J, Garman, E.F, Antrobus, R, Lea, S.M, Berks, B.C. 登録日 2009-03-24 公開日 2009-06-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Mechanism for the Hydrolysis of a Sulfur-Sulfur Bond Based on the Crystal Structure of the Thiosulfohydrolase Soxb. J.Biol.Chem., 284, 2009
1XYU	Solution structure of the sheep prion protein with polymorphism H168 分子名称: Major prion protein 著者 Calzolai, L, Lysek, D.A, Guntert, P, Wuthrich, K. 登録日 2004-11-11 公開日 2005-01-04 最終更新日 2024-10-30 実験手法 SOLUTION NMR 主引用文献 Prion protein NMR structures of cats, dogs, pigs, and sheep Proc.Natl.Acad.Sci.USA, 102, 2005
4IVH	Crystal structure of QKLVFFAED nonapeptide segment from amyloid beta incorporated into a macrocyclic beta-sheet template 分子名称: SODIUM ION, TERTIARY-BUTYL ALCOHOL, cyclo[Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-(delta-linked-Orn)-Hao-Lys-Hao-(p-bromoPhe)-Thr-(delta-linked-Orn)] 著者 Pham, J.D, Chim, N, Goulding, C.W, Nowick, J.S. 登録日 2013-01-22 公開日 2013-07-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structures of beta-Amyloid Peptide Oligomers J.Am.Chem.Soc., 2013
3GST	STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE 分子名称: (9R,10R)-9-(S-GLUTATHIONYL)-10-HYDROXY-9,10-DIHYDROPHENANTHRENE, GLUTATHIONE S-TRANSFERASE, SULFATE ION 著者 Ji, X, Ammon, H.L, Armstrong, R.N, Gilliland, G.L. 登録日 1993-06-07 公開日 1993-10-31 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene. Biochemistry, 33, 1994
3X1J	Crystal Structure of Phosphopantetheine adenylyltransferase (PPAT/CoaD) with AcCoA from Pseudomonas aeruginosa 分子名称: ACETYL COENZYME *A, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Chatterjee, R, Datta, S. 登録日 2014-11-19 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.334 Å) 主引用文献 Transition of phosphopantetheine adenylyltransferase from catalytic to allosteric state is characterized by ternary complex formation in Pseudomonas aeruginosa Biochim.Biophys.Acta, 1864, 2016
1Y9A	Alcohol Dehydrogenase from Entamoeba histolotica in complex with cacodylate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CACODYLATE ION, ... 著者 Shimon, L.J, Peretz, M, Goihberg, E, Burstein, Y, Frolow, F. 登録日 2004-12-15 公開日 2006-01-17 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Structure of alcohol dehydrogenase from Entamoeba histolytica. Acta Crystallogr.,Sect.D, 62, 2006
4JJC	Crystal structure of the Abl-SH3 domain at pH5 分子名称: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1 著者 Camara-Artigas, A, Martin-Garcia, J.M. 登録日 2013-03-07 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the Abl-SH3 domain at pH5 To be Published
1Y2S	Ovine Prion Protein Variant R168 分子名称: Major prion protein 著者 Christen, B, Lysek, D.A, Herrmann, T, Wuthrich, K. 登録日 2004-11-23 公開日 2004-12-28 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Prion protein NMR structures of cats, dogs, pigs, and sheep Proc.Natl.Acad.Sci.USA, 102, 2005
1HMH	THREE-DIMENSIONAL STRUCTURE OF A HAMMERHEAD RIBOZYME 分子名称: HAMMERHEAD RIBOZYME-DNA STRAND, HAMMERHEAD RIBOZYME-RNA STRAND 著者 Pley, H.W, Flaherty, K.M, McKay, D.B. 登録日 1995-06-06 公開日 1995-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Three-dimensional structure of a hammerhead ribozyme. Nature, 372, 1994
3PB0	Characterisation of the first monomeric dihydrodipicolinate synthase variant reveals evolutionary insights 分子名称: Dihydrodipicolinate synthase, SULFATE ION 著者 Pearce, F.G, Dobson, R.C.J, Jameson, G.B. 登録日 2010-10-19 公開日 2011-11-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization. Biochim.Biophys.Acta, 1814, 2011
4E3T	Round 18 Arylesterase Variant of Phosphotriesterase with Bound Transition State Analog 分子名称: Phosphotriesterase, ZINC ION, hexyl(naphthalen-2-yloxy)phosphinic acid 著者 Tokuriki, N, Jackson, C.J, Tawfik, D.S. 登録日 2012-03-10 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme Nat Commun, 3, 2012
1H89	CRYSTAL STRUCTURE OF TERNARY PROTEIN-DNA COMPLEX2 分子名称: CAAT/ENHANCER BINDING PROTEIN BETA, DNA(5'-(*CP*CP*AP*GP*TP*CP*CP*GP*TP*TP*AP* AP*GP*GP*AP*TP*TP*GP*CP*GP*CP*CP*AP*CP*AP*T)-3'), DNA(5'-(*GP*AP*TP*GP*TP*GP*GP*CP*GP*CP*AP* AP*TP*CP*CP*TP*TP*AP*AP*CP*GP*GP*AP*CP*TP*G)-3'), ... 著者 Tahirov, T.H, Ogata, K. 登録日 2001-01-30 公開日 2002-01-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter Cell(Cambridge,Mass.), 108, 2002
4MJO	Human liver fructose-1,6-bisphosphatase(d-fructose-1,6-bisphosphate, 1-phosphohydrolase) (e.c.3.1.3.11) complexed with the allosteric inhibitor 3 分子名称: Fructose-1,6-bisphosphatase 1, N-({4-bromo-6-[(methylcarbamoyl)amino]pyridin-2-yl}carbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide 著者 Ruf, A, Joseph, C, Tetaz, T, Benz, J. 登録日 2013-09-04 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Determination of protein-ligand binding constants of a cooperatively regulated tetrameric enzyme using electrospray mass spectrometry. Acs Chem.Biol., 9, 2014
4MM1	GGGPS from Methanothermobacter thermautotrophicus 分子名称: Geranylgeranylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE, TRIETHYLENE GLYCOL 著者 Rajendran, C, Peterhoff, D, Beer, B, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. 登録日 2013-09-07 公開日 2014-06-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.8004 Å) 主引用文献 A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
5OIP	InhA (T2A mutant) complexed with 1-(Pyridin-3-ylmethyl)-3-(1-(pyrimidin-2-yl)piperidin-4-yl)urea 分子名称: 1-(pyridin-3-ylmethyl)-3-(1-pyrimidin-2-ylpiperidin-4-yl)urea, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Convery, M.A. 登録日 2017-07-19 公開日 2018-02-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA. ChemMedChem, 13, 2018
6ZNR	MaeB PTA domain R535A mutant 分子名称: Malate dehydrogenase 著者 Lovering, A.L, Harding, C.J. 登録日 2020-07-06 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.217 Å) 主引用文献 A rotary mechanism for allostery in bacterial hybrid malic enzymes. Nat Commun, 12, 2021
6ZNJ	MaeB full-length enzyme apoprotein form 分子名称: NADP-dependent malate dehydrogenase,Malate dehydrogenase 著者 Lovering, A.L, Harding, C.J. 登録日 2020-07-06 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 A rotary mechanism for allostery in bacterial hybrid malic enzymes. Nat Commun, 12, 2021
1EE2	THE STRUCTURE OF STEROID-ACTIVE ALCOHOL DEHYDROGENASE AT 1.54 A RESOLUTION 分子名称: ALCOHOL DEHYDROGENASE, CHOLIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Adolph, H.W. 登録日 2000-01-30 公開日 2000-10-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes. Biochemistry, 39, 2000
6ZN7	MaeB malic enzyme domain apoprotein 分子名称: MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malate dehydrogenase,Malate dehydrogenase 著者 Lovering, A.L, Harding, C.J. 登録日 2020-07-06 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 A rotary mechanism for allostery in bacterial hybrid malic enzymes. Nat Commun, 12, 2021
6ZN4	MaeB malic enzyme domain apoprotein 分子名称: MAGNESIUM ION, NADP-dependent malate dehydrogenase,Malate dehydrogenase 著者 Lovering, A.L, Harding, C.J. 登録日 2020-07-06 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.679 Å) 主引用文献 A rotary mechanism for allostery in bacterial hybrid malic enzymes. Nat Commun, 12, 2021
6ROB	Human Carbonic Anhydrase II in complex with 4-cyanobenzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-cyanobenzenesulfonamide, Carbonic anhydrase 2, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-05-10 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.929 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
6ZN9	MaeB PTA domain apoprotein 分子名称: Malate dehydrogenase 著者 Lovering, A.L, Harding, C.J. 登録日 2020-07-06 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 A rotary mechanism for allostery in bacterial hybrid malic enzymes. Nat Commun, 12, 2021
6ZNU	MaeB PTA domain E544R mutant 分子名称: ACETYL COENZYME *A, CHLORIDE ION, Malate dehydrogenase 著者 Lovering, A.L, Harding, C.J. 登録日 2020-07-06 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 A rotary mechanism for allostery in bacterial hybrid malic enzymes. Nat Commun, 12, 2021
6ZNG	MaeB full-length acetyl-CoA bound state 分子名称: ACETYL COENZYME *A, NADP-dependent malate dehydrogenase,Malate dehydrogenase 著者 Lovering, A.L, Harding, C.J. 登録日 2020-07-06 公開日 2021-02-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 A rotary mechanism for allostery in bacterial hybrid malic enzymes. Nat Commun, 12, 2021

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