PDB: 82203 件ウェブページステータス検索Chemie searchBIRD

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2VS1	The crystal structure of Pyrococcus abyssi tRNA (uracil-54, C5)- methyltransferase in complex with S-adenosyl-L-homocysteine 分子名称: PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, UNCHARACTERIZED RNA METHYLTRANSFERASE PYRAB10780 著者 Walbott, H, Leulliot, N, Grosjean, H, Golinelli-Pimpaneau, B. 登録日 2008-04-17 公開日 2008-08-05 最終更新日 2017-07-12 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity. Nucleic Acids Res., 36, 2008
4Y9Z	Yeast 20S proteasome beta2-H116E mutant in complex with Ac-LAE-ep 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAE-ep, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-17 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
4Y8K	Yeast 20S proteasome in complex with H-APLL-ep 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, H-APLL-ep, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-16 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
4YA3	Yeast 20S proteasome beta2-H116N mutant in complex with Ac-PAE-ep 分子名称: Ac-PAE-ep, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-17 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
2WEB	ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL(2S)-[1-(((N-FORMYL)-L-VALYL)AMINO-2-(2-NAPHTHYL)ETHYL)HYDROXYPHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT 分子名称: METHYL (2S)-[1-((N-FORMYL)-L-VALYL)AMINO-2-(2-NAPHTHYL)ETHYL)HYDROXYPHOSPHINYLOXY]-3-PHENYL PROPANOATE, PENICILLOPEPSIN, SULFATE ION, ... 著者 Ding, J, Fraser, M.E, James, M.N.G. 登録日 1998-02-03 公開日 1998-05-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Macrocyclic Inhibitors of Penicillopepsin. II. X-Ray Crystallographic Analyses of Penicillopepsin Complexed with a P3-P1 Macrocyclic Peptidyl Inhibitor and with its Two Acyclic Analogues J.Am.Chem.Soc., 120, 1998
6F06	CATHEPSIN L IN COMPLEX WITH (3S,14E)-8-(azetidin-3-yl)-19-chloro-N-(1-cyanocyclopropyl)-5-oxo-12,17-dioxa-4-azatricyclo[16.2.2.06,11]docosa-1(21),6,8,10,14,18(22),19-heptaene-3-carboxamide 分子名称: (3~{S},14~{E})-8-(azetidin-3-yl)-19-chloranyl-~{N}-(1-cyanocyclopropyl)-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6(11),7,9,14,18(22),19-heptaene-3-carboxamide, CHLORIDE ION, Cathepsin L1, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2017-11-17 公開日 2018-04-11 最終更新日 2018-05-09 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. J. Med. Chem., 61, 2018
1CD2	LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+ 分子名称: DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A. 登録日 1999-03-05 公開日 2000-03-06 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+. Biochemistry, 38, 1999
6HJK	Crystal Structure of Aurora-A L210C catalytic domain in complex with ASDO2 分子名称: (~{E})-~{N}-[4-(4-azanyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-4-[4-fluoranyl-3-(trifluoromethyl)phenyl]-4-oxidanylidene-but-2-enamide, Aurora kinase A, CHLORIDE ION, ... 著者 Bayliss, R, McIntyre, P.J. 登録日 2018-09-04 公開日 2018-10-03 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases. ACS Chem. Biol., 13, 2018
2WEC	ACID PROTEINASE (PENICILLOPEPSIN) (E.C.3.4.23.20) COMPLEX WITH PHOSPHONATE INHIBITOR: METHYL(2S)-[1-(((N-(1-NAPHTHALENEACETYL))-L-VALYL)AMINOMETHYL)HYDROXY PHOSPHINYLOXY]-3-PHENYLPROPANOATE, SODIUM SALT 分子名称: METHYL (2S)-[1-((N-(NAPHTHALENEACETYL))-L-VALYL)AMINOMETHYL)HYDROXYPHOSPHINYLOXY]-3-PHENYL PROPANOATE, PENICILLOPEPSIN, SULFATE ION, ... 著者 Ding, J, Fraser, M.E, James, M.N.G. 登録日 1998-02-03 公開日 1998-05-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Macrocyclic Inhibitors of Penicillopepsin. II. X-Ray Crystallographic Analyses of Penicillopepsin Complexed with a P3-P1 Macrocyclic Peptidyl Inhibitor and with its Two Acyclic Analogues J.Am.Chem.Soc., 120, 1998
4Y74	Yeast 20S proteasome in complex with Ac-LAL-ep 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAL-ep, CHLORIDE ION, ... 著者 Groll, M, Huber, E.M. 登録日 2015-02-13 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
2X2R	Crystal structure of human kinesin Eg5 in complex with (R)-2-amino-3-((4-chlorophenyl)diphenylmethylthio)propanoic acid 分子名称: (2R)-2-AMINO-3-[(2R)-2-METHYL-1,1-DIPHENYL-BUTYL]SULFANYL-PROPANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ... 著者 Kaan, H.Y.K, Weiss, J, Menger, D, Ulaganathan, V, Laggner, C, Popowycz, F, Joseph, B, Kozielski, F. 登録日 2010-01-15 公開日 2011-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Activity Relationship and Multidrug Resistance Study of New S-Trityl-L-Cysteine Derivatives as Inhibitors of Eg5. J.Med.Chem., 54, 2011
4Y6V	Yeast 20S proteasome in complex with Ac-PAE-ep 分子名称: Ac-PAE-ep, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-13 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
4Y8U	Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAD-ep 分子名称: Ac-PAD-ep, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-16 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
4YA5	Yeast 20S proteasome beta2-H114D mutant in complex with Ac-PAE-ep 分子名称: Ac-PAE-ep, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-17 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
8KE2	PylRS C-terminus domain mutant bound with L-3-trifluoromethylphenylalanine and AMPNP 分子名称: (2S)-2-azanyl-3-[3-(trifluoromethyl)phenyl]propanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Weng, J.H, Tsai, M.D, Wang, Y.S. 登録日 2023-08-11 公開日 2023-11-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.19639969 Å) 主引用文献 Rational design of the genetic code expansion toolkit for in vivo encoding of D-amino acids. Front Genet, 14, 2023
8ODT	Structure of TolQR complex from E.coli 分子名称: Tol-Pal system protein TolQ, Tol-Pal system protein TolR 著者 Webby, M.N, Kleanthous, C, Press, C.E. 登録日 2023-03-09 公開日 2023-11-01 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Tunable force transduction through the Escherichia coli cell envelope. Proc.Natl.Acad.Sci.USA, 120, 2023
4Y78	Yeast 20S proteasome in complex with Ac-LAD-ep 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAD-ep, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-13 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
6FU9	Complex of rice blast (Magnaporthe oryzae) effector protein AVR-PikD with the HMA domain of Pikm-1 from rice (Oryza sativa) 分子名称: AVR-Pik protein, NBS-LRR class disease resistance protein 著者 Franceschetti, M, De la Concepcion, J.C, Banfield, M.J. 登録日 2018-02-26 公開日 2018-06-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Polymorphic residues in rice NLRs expand binding and response to effectors of the blast pathogen. Nat Plants, 4, 2018
8JXQ	Cryo-EM structure of bilirubin ditaurate (BDT) bound human ABC transporter ABCC2 分子名称: 2-[3-[5-[(E)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-3-[3-oxidanylidene-3-(2-sulfoethylamino)propyl]-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoylamino]ethanesulfonic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL 著者 Mao, Y.X, Chen, Z.P, Wang, L, Hou, W.T, Chen, Y.X, Zhou, C.Z. 登録日 2023-07-01 公開日 2024-01-03 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Transport mechanism of human bilirubin transporter ABCC2 tuned by the inter-module regulatory domain. Nat Commun, 15, 2024
4Y70	Yeast 20S proteasome in complex with Ac-LAV-ep 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAV-ep, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-13 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
4Y8P	Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAL-ep 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAL-ep, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-16 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
7JO9	1:1 cGAS-nucleosome complex 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... 著者 Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. 登録日 2020-08-06 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
6HJJ	Crystal structure of Aurora-A L210C catalytic domain in complex with ASDO6 ligand 分子名称: 2,5,8,11-TETRAOXATRIDECANE, ACETATE ION, Aurora kinase A, ... 著者 Bayliss, R, McIntyre, P.J. 登録日 2018-09-04 公開日 2018-10-03 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases. ACS Chem. Biol., 13, 2018
4YA0	Yeast 20S proteasome beta2-H116E mutant in complex with Ac-PAE-ep 分子名称: Ac-PAE-ep, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-17 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
6FUB	Complex of rice blast (Magnaporthe oryzae) effector protein AVR-PikE with the HMA domain of Pikm-1 from rice (Oryza sativa) 分子名称: AVR-Pik protein, NBS-LRR class disease resistance protein 著者 Franceschetti, M, De la Concepcion, J.C, Banfield, M.J. 登録日 2018-02-26 公開日 2018-06-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Polymorphic residues in rice NLRs expand binding and response to effectors of the blast pathogen. Nat Plants, 4, 2018

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