PDB: 36840 件ウェブページステータス検索Chemie searchBIRD

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2YCR	Crystal structure of checkpoint kinase 2 in complex with inhibitor PV976 分子名称: 1,3-BIS{4-[(1E)-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)ETHANEHYDRAZONOYL]PHENYL}UREA, NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 著者 Lountos, G.T, Jobson, A.G, Tropea, J.E, Self, C.R, Pommier, Y, Shoemaker, R.H, Zhang, G, Waugh, D.S. 登録日 2011-03-16 公開日 2011-11-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Characterization of Inhibitor Complexes with Checkpoint Kinase 2 (Chk2), a Drug Target for Cancer Therapy. J.Struct.Biol., 176, 2011
5P68	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 269 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P1O	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 107 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.515 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P6N	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 284 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.109 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P72	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 299 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.049 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P1Y	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 117 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.518 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P7F	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 312 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.079 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1WSE	Co-crystal structure of E.coli RNase HI active site mutant (E48A*) with Mn2+ 分子名称: MANGANESE (II) ION, Ribonuclease HI 著者 Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. 登録日 2004-11-05 公開日 2005-02-08 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography J.Mol.Biol., 345, 2005
5P2C	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 130 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P7Y	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 331 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.654 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P8E	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 347 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.219 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1WFO	The eighth FN3 domain of human sidekick-2 分子名称: sidekick 2 著者 Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-05-26 公開日 2005-06-07 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The eighth FN3 domain of human sidekick-2 TO BE PUBLISHED
5P2Q	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 143 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1HPT	THREE-DIMENSIONAL STRUCTURE OF A RECOMBINANT VARIANT OF HUMAN PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE) 分子名称: PANCREATIC SECRETORY TRYPSIN INHIBITOR (KAZAL TYPE) VARIANT 3 著者 Hecht, H.J, Szardenings, M, Collins, J, Schomburg, D. 登録日 1992-03-27 公開日 1993-10-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (Kazal type). J.Mol.Biol., 225, 1992
5P34	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 157 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.209 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P8T	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 362 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P3I	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 171 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P3Z	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 188 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.196 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
2CPP	HIGH-RESOLUTION CRYSTAL STRUCTURE OF CYTOCHROME P450-CAM 分子名称: CAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Poulos, T.L. 登録日 1987-04-06 公開日 1987-07-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 High-resolution crystal structure of cytochrome P450cam. J.Mol.Biol., 195, 1987
5P4E	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 203 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
1S81	PORCINE TRYPSIN WITH NO INHIBITOR BOUND 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ... 著者 Transue, T.R, Krahn, J.M, Gabel, S.A, DeRose, E.F, London, R.E. 登録日 2004-01-30 公開日 2004-03-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 X-ray and NMR characterization of covalent complexes of trypsin, borate, and alcohols. Biochemistry, 43, 2004
3FPM	Crystal Structure of a Squarate Inhibitor bound to MAPKAP Kinase-2 分子名称: 3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione, MAP kinase-activated protein kinase 2 著者 Parris, K.D. 登録日 2009-01-05 公開日 2009-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Identification and SAR of squarate inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2) Bioorg.Med.Chem., 17, 2009
5P4W	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 221 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P5C	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 237 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.339 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P5R	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 252 分子名称: endothiapepsin 著者 Schiebel, J, Heine, A, Klebe, G. 登録日 2016-06-28 公開日 2016-08-03 最終更新日 2021-11-17 実験手法 X-RAY DIFFRACTION (1.308 Å) 主引用文献 High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016

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