PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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6H7R	Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant 分子名称: 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, GLYCEROL 著者 Crennell, S.J, Danson, M.J, Royer, S. 登録日 2018-07-31 公開日 2019-08-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant To Be Published
4I9M	Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES 分子名称: 1-phosphatidylinositol phosphodiesterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION 著者 Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. 登録日 2012-12-05 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288, 2013
1DUM	NMR STRUCTURE OF [F5Y, F16W] MAGAININ 2 BOUND TO PHOSPHOLIPID VESICLES 分子名称: MAGAININ 2 著者 Takeda, A, Wakamatsu, K, Tachi, T, Matsuzaki, K. 登録日 2000-01-18 公開日 2001-06-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Effects of peptide dimerization on pore formation: Antiparallel disulfide-dimerized magainin 2 analogue. Biopolymers, 58, 2001
6H36	The crystal structure of human carbonic anhydrase VII in complex with 4-(4-phenylpiperidine-1-carbonyl)benzenesulfonamide. 分子名称: 4-(4-phenylpiperidin-1-yl)carbonylbenzenesulfonamide, Carbonic anhydrase 7, ZINC ION 著者 Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R. 登録日 2018-07-17 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. Eur J Med Chem, 163, 2018
6YPL	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-037 分子名称: (2-methylsulfonylphenyl)methanol, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-16 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6YQU	CRYSTAL STRUCTURE OF HUMAN CA II IN COMPLEX WITH 2-MERCAPTOBENZOXAZOLE 分子名称: 3~{H}-1,3-benzoxazole-2-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Alterio, V, De Simone, G, Esposito, D. 登録日 2020-04-18 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.478 Å) 主引用文献 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site. Chem.Commun.(Camb.), 56, 2020
1O1A	MOLECULAR MODELS OF AVERAGED RIGOR CROSSBRIDGES FROM TOMOGRAMS OF INSECT FLIGHT MUSCLE 分子名称: SKELETAL MUSCLE ACTIN, SKELETAL MUSCLE MYOSIN II, SKELETAL MUSCLE MYOSIN II ESSENTIAL LIGHT CHAIN, ... 著者 Chen, L.F, Winkler, H, Reedy, M.K, Reedy, M.C, Taylor, K.A. 登録日 2002-11-18 公開日 2002-12-04 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (70 Å) 主引用文献 Molecular Modeling of Averaged Rigor Crossbridges from Tomograms of Insect Flight Muscle J.Struct.Biol., 138, 2002
5KVJ	Crystal structure of the 16-mer doublestranded RNA. Northeast Structural Genomics Consortium (NESG) target RNA1 分子名称: ARGININE, RNA (5'-R(P*CP*CP*AP*UP*CP*CP*UP*CP*UP*AP*CP*AP*GP*GP*CP*G)-3'), RNA (5'-R(P*CP*GP*CP*CP*UP*GP*UP*AP*GP*AP*GP*GP*AP*UP*GP*G)-3') 著者 Vorobiev, S.M, Ma, L.-C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2016-07-14 公開日 2016-08-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.261 Å) 主引用文献 Crystal structure of the 16-mer double stranded RNA. To be published
3I85	The Crystal Structure of Human EMMPRIN N-terminal Domain 1 分子名称: Cervical EMMPRIN 著者 Luo, J, Gilliland, G.L. 登録日 2009-07-09 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the EMMPRIN N-terminal domain 1: Dimerization via beta-strand swapping. Proteins, 77, 2009
3WFW	Crystal Structure of the Closed Form of the HGbRL's Globin Domain 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Hemoglobin-like flavoprotein fused to Roadblock/LC7 domain, PROTOPORPHYRIN IX CONTAINING FE 著者 Teh, A.H. 登録日 2013-07-24 公開日 2014-08-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Open and Lys-His Hexacoordinated Closed Structures of a Globin with Swapped Proximal and Distal Sites. Sci Rep, 5, 2015
4I9T	Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus 分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, SULFATE ION, ... 著者 Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. 登録日 2012-12-05 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288, 2013
6YE9	Small-molecule inhibitor of 14-3-3 protein-protein interactions 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, [2-[2-oxidanylidene-2-[(phenylmethyl)amino]ethoxy]phenyl]phosphonic acid 著者 Ottmann, C, Visser, E.J. 登録日 2020-03-24 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-based conversion of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions To Be Published
3WNR	Multiple binding modes of benzyl isothiocyanate inhibitor complexed with Macrophage Migration Inhibitory Factor 分子名称: CHLORIDE ION, GLYCEROL, Macrophage migration inhibitory factor, ... 著者 Spencer, E.S, Dale, E.J, Gommans, A.L, Rutledge, M.T, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. 登録日 2013-12-16 公開日 2014-03-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.008 Å) 主引用文献 Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93, 2015
6YRI	THE CRYSTAL STRUCTURE OF THE COMPLEX OF HCAII WITH CAFFEIC ACID 分子名称: CAFFEIC ACID, Carbonic anhydrase 2, GLYCEROL, ... 著者 D'Ambrosio, K, De Simone, G. 登録日 2020-04-20 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Catechols: a new class of carbonic anhydrase inhibitors. Chem.Commun.(Camb.), 56, 2020
1EMA	GREEN FLUORESCENT PROTEIN FROM AEQUOREA VICTORIA 分子名称: GREEN FLUORESCENT PROTEIN 著者 Ormo, M, Remington, S.J. 登録日 1996-08-01 公開日 1996-11-08 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the Aequorea victoria green fluorescent protein. Science, 273, 1996
5LIY	Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK204 分子名称: 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. 登録日 2016-07-15 公開日 2016-10-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
8D34	Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A 分子名称: Uridylate-specific endoribonuclease nsp15 著者 Farraj, R.A, Edwards, R.A, Glover, J.N.M. 登録日 2022-05-31 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Crystal Structure of SARS CoV-2 NSP15 Endroribonuclease H250A To Be Published
6YR2	TetR(D) soaked with Tigecycline P4(1)2(1)2 分子名称: CHLORIDE ION, MAGNESIUM ION, SULFATE ION, ... 著者 Hinrichs, W, Stary, K. 登録日 2020-04-19 公開日 2021-04-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 TetR(D) soaked with Tigecycline to be published
8D3S	HIV-1 Integrase Catalytic Core Domain F185H Mutant Complexed with BKC-110 分子名称: (2S)-tert-butoxy{4-(4-chlorophenyl)-2,6-dimethyl-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}acetic acid, Integrase 著者 Dinh, T, Kvaratskhelia, M. 登録日 2022-06-01 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 HIV-1 Integrase Catalytic Core Domain Complexed with BKC-110 To Be Published
6YR1	TetR(D) soaked with Tigecycline I4(1)22 分子名称: CHLORIDE ION, MAGNESIUM ION, TIGECYCLINE, ... 著者 Hinrichs, W, Stary, K. 登録日 2020-04-18 公開日 2021-04-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 TetR(D) soaked with Tigecycline to be published
8DEI	Structure of the Cac1 KER domain 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Maltodextrin-binding protein,Chromatin assembly factor 1 subunit p90 fusion, ... 著者 Rosas, R, Churchill, M.E.A. 登録日 2022-06-20 公開日 2023-07-05 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 A novel single alpha-helix DNA-binding domain in CAF-1 promotes gene silencing and DNA damage survival through tetrasome-length DNA selectivity and spacer function. Elife, 12, 2023
3ISB	Binary complex of human DNA polymerase beta with a gapped DNA 分子名称: 5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H. 登録日 2009-08-25 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 DNA polymerase beta substrate specificity: side chain modulation of the "A-rule". J.Biol.Chem., 284, 2009
1NHE	Crystal structure of Lactose synthase complex with UDP 分子名称: ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, CALCIUM ION, ... 著者 Ramakrishnan, B, Qasba, P.K. 登録日 2002-12-19 公開日 2003-01-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta-1,4-galactosyltransferase J.Mol.Biol., 310, 2001
1NF5	Crystal Structure of Lactose Synthase, Complex with Glucose 分子名称: 1,2-ETHANEDIOL, Alpha-lactalbumin, CALCIUM ION, ... 著者 Ramakrishnan, B, Qasba, P.K. 登録日 2002-12-13 公開日 2002-12-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Lactose Synthase Reveals a Large Conformational Change in its Catalytic Component, the beta-1,4-galactosyltransferase J.Mol.Biol., 310, 2001
5M3A	Crystal structure of BRD4 BROMODOMAIN 1 IN COMPLEX WITH LIGAND 2 分子名称: 1,2-ETHANEDIOL, 3-methyl-6-(1-methyl-5-phenoxy-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine, Bromodomain-containing protein 4 著者 Kessler, D, Mayer, M, Engelhardt, H, Wolkerstorfer, B, Geist, L. 登録日 2016-10-14 公開日 2017-09-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Direct NMR Probing of Hydration Shells of Protein Ligand Interfaces and Its Application to Drug Design. J. Med. Chem., 60, 2017

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