PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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4UW0	Low resolution structure of WbdD with C-terminal bundle ordered to residue 505 分子名称: S-ADENOSYLMETHIONINE, WBDD 著者 Hagelueken, G, Huang, H, Naismith, J.H. 登録日 2014-08-08 公開日 2014-08-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.87 Å) 主引用文献 A Coiled-Coil Domain Acts as a Molecular Ruler to Regulate O-Antigen Chain Length in Lipopolysaccharide. Nat.Struct.Mol.Biol., 22, 2015
6E2Y	MDDEF in complex with MVAPP, ADP, sulfate and cobalt. Anomalous data 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, COBALT (II) ION, ... 著者 Stauffacher, C.V, Chen, C.-L. 登録日 2018-07-12 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase. Nat Commun, 11, 2020
7YOD	Crystal structure of A68P single mutant of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high-affinity inhibitory peptide from serine acetyltransferase of Salmonella typhimurium at 2.1 A 分子名称: Cysteine synthase, peptide from serine acetyltransferase 著者 Kumar, N, Rahisuddin, R, Saini, N, Singh, A.K. 登録日 2022-08-01 公開日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Crystal structure of A68P single mutant of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high-affinity inhibitory peptide from serine acetyltransferase of Salmonella typhimurium at 2.1 A To Be Published
4UYD	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1,3-dimethyl-2-oxo-2,3- dihydro-1H-1,3-benzodiazole-5-carboxamide 分子名称: 1,2-ETHANEDIOL, 1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-carboxamide, BROMODOMAIN-CONTAINING PROTEIN 4, ... 著者 Chung, C, Bamborough, P, Demont, E. 登録日 2014-08-30 公開日 2014-09-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 1,3-Dimethyl Benzimidazolones are Potent, Selective Inhibitors of the Brpf1 Bromodomain. Acs Med.Chem.Lett., 5, 2014
4UZS	Crystal structure of Bifidobacterium bifidum beta-galactosidase 分子名称: BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Godoy, A.S, Murakami, M.T, Camilo, C.M, Bernardes, A, Polikarpov, I. 登録日 2014-09-08 公開日 2015-09-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal Structure of Beta1-6-Galactosidase from Bifidobacterium Bifidum S17: Trimeric Architecture, Molecular Determinants of the Enzymatic Activity and its Inhibition by Alpah-Galactose. FEBS J., 283, 2016
6E31	Crystal structure of RIAM in an autoinhibited configuration. 分子名称: Rap1-interacting adapter molecule 著者 Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J. 登録日 2018-07-12 公開日 2019-02-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
3MFV	Crystal structure of human arginase I in complex with 2-aminohomohistidine 分子名称: (2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic acid, Arginase-1, MANGANESE (II) ION 著者 Di Costanzo, L, Christianson, D.W. 登録日 2010-04-04 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J.Med.Chem., 53, 2010
6E37	O-GlcNAc Transferase in complex with covalent inhibitor 分子名称: (2S,3R,4R,5S,6R)-3-[(2E)-but-2-enoylamino]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name), O-GlcNAc transferase subunit p110, TYR-PRO-GLY-GLY-SER-THR-PRO-VAL-SER-SER-ALA-ASN 著者 Li, H, Jiang, J. 登録日 2018-07-13 公開日 2019-11-06 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.531 Å) 主引用文献 Targeted covalent inhibition of O-GlcNAc transferase in cells. Chem.Commun.(Camb.), 55, 2019
4USM	WcbL complex with glycerol bound to sugar site 分子名称: CHLORIDE ION, GLYCEROL, PUTATIVE SUGAR KINASE 著者 Vivoli, M, Isupov, M.N, Nicholas, R, Hill, A, Scott, A, Kosma, P, Prior, J, Harmer, N.J. 登録日 2014-07-10 公開日 2016-01-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Unraveling the B.Pseudomallei Heptokinase Wcbl: From Structure to Drug Discovery. Chem.Biol., 22, 2015
4V3X	Structure of rat neuronal nitric oxide synthase heme domain in complex with N-2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)ethyl-3-(3- fluorophenyl)propan-1-amine 分子名称: 3-(3-fluorophenyl)-N-{2-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]ethyl}propan-1-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2014-10-20 公開日 2014-12-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase. J.Med.Chem., 58, 2015
4UTM	XenA - Reduced - Y183F variant in complex with 8-hydroxycoumarin 分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 8-HYDROXYCOUMARIN, SULFATE ION, ... 著者 Werther, T, Dobbek, H. 登録日 2014-07-21 公開日 2015-08-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Redox-dependent substrate-cofactor interactions in the Michaelis-complex of a flavin-dependent oxidoreductase Nat Commun, 8, 2017
6E3A	tRNA 2'-phosphotransferase 分子名称: COENZYME A, Probable RNA 2'-phosphotransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate 著者 Shuman, S, Goldgur, Y, Banerjee, A. 登録日 2018-07-13 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of tRNA splicing enzyme Tpt1 illuminates the mechanism of RNA 2'-PO4recognition and ADP-ribosylation. Nat Commun, 10, 2019
6EJ6	Crystal structure of the N240A mutant of Candida albicans Mep2 分子名称: Ammonium transporter 著者 van den Berg, B. 登録日 2017-09-20 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the N240A mutant of Candida albicans Mep2 To Be Published
7YOM	Crystal structure of tetra mutant (D67E,A68P,L98I,A301S) of O-acetylserine sulfhydrylase from Salmonella typhimurium in complex with high-affinity inhibitory peptide from serine acetyltransferase of Salmonella typhimurium at 2.8 A 分子名称: Cysteine synthase, peptide from serine acetyltransferase 著者 Saini, N, Kumar, N, Rahisuddin, R, Singh, A.K. 登録日 2022-08-01 公開日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of I88L single mutant of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with high-affinity inhibitory peptide from serine acetyltransferase of Salmonella typhimurium at 2.14 A To Be Published
4UVY	Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methoxy-1,2- dihydroisoquinolin-1-one 分子名称: 3-(4-chlorophenyl)-5-methoxyisoquinolin-1(2H)-one, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
4UYI	Crystal structure of the BTB domain of human SLX4 (BTBD12) 分子名称: STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 著者 Pinkas, D.M, Sanvitale, C.E, Strain-Damerell, C, Fairhead, M, Wang, D, Tallant, C, Cooper, C.D.O, Sorrell, F.J, Kopec, J, Chaikuad, A, Fitzpatrick, F, Pike, A.C.W, Hozjan, V, Ying, Z, Roos, A.K, Savitsky, P, Bradley, A, Nowak, R, Filippakopoulos, P, Krojer, T, Burgess-Brown, N.A, Marsden, B.D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. 登録日 2014-09-01 公開日 2014-10-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Crystal Structure of the Btb Domain of Human Slx4 (Btbd12) To be Published
4V02	MinC:MinD cell division protein complex, Aquifex aeolicus 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROBABLE SEPTUM SITE-DETERMINING PROTEIN MINC, ... 著者 Ghosal, D, Lowe, J. 登録日 2014-09-10 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mincd Cell Division Proteins Form Alternating Copolymeric Cytomotive Filaments. Nat.Commun., 5, 2014
4UR3	Crystal structure of the PCE reductive dehalogenase from S. multivorans P2(1) crystal form 分子名称: IRON/SULFUR CLUSTER, NORPSEUDO-B12, TETRACHLOROETHENE REDUCTIVE DEHALOGENASE CATALYTIC SUBUNIT 著者 Bommer, M, Kunze, C, Fesseler, J, Schubert, T, Diekert, G, Dobbek, H. 登録日 2014-06-25 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.235 Å) 主引用文献 Structural Basis for Organohalide Respiration. Science, 346, 2014
4UR2	Crystal structure of the PCE reductive dehalogenase from S. multivorans in complex with iodide 分子名称: GLYCEROL, IODIDE ION, IRON/SULFUR CLUSTER, ... 著者 Bommer, M, Kunze, C, Fesseler, J, Schubert, T, Diekert, G, Dobbek, H. 登録日 2014-06-25 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Structural Basis for Organohalide Respiration. Science, 346, 2014
4UUY	Structural Identification of the Vps18 beta-propeller reveals a critical role in the HOPS complex stability and function. 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... 著者 Behrmann, H, Gohlke, U, Heinemann, U. 登録日 2014-08-01 公開日 2014-10-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structural Identification of the Vps18 Beta-Propeller Reveals a Critical Role in the Hops Complex Stability and Function. J.Biol.Chem., 289, 2014
4UXJ	Leishmania major Thymidine Kinase in complex with dTTP 分子名称: MAGNESIUM ION, THYMIDINE KINASE, THYMIDINE-5'-TRIPHOSPHATE, ... 著者 Timm, J, Bosch-Navarrete, C, Recio, E, Nettleship, J.E, Rada, H, Gonzalez-Pacanowska, D, Wilson, K.S. 登録日 2014-08-22 公開日 2015-05-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural and Kinetic Characterization of Thymidine Kinase from Leishmania Major. Plos Negl Trop Dis, 9, 2015
4UVW	Crystal structure of human tankyrase 2 in complex with 4,5-dimethyl-3- phenyl-1,2-dihydroisoquinolin-1-one 分子名称: 4,5-dimethyl-3-phenylisoquinolin-1(2H)-one, SULFATE ION, TANKYRASE-2, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
4UZZ	Crystal structure of the TtIFT52-46 complex 分子名称: INTRAFLAGELLAR TRANSPORT COMPLEX B PROTEIN 46 CARBOXY-TERMINAL PROTEIN, INTRAFLAGELLAR TRANSPORTER-LIKE PROTEIN 著者 Braeuer, P, Taschner, M, Lorentzen, E. 登録日 2014-09-09 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.318 Å) 主引用文献 Crystal Structures of Ift70/52 and Ift52/46 Provide Insight Into Intraflagellar Transport B Core Complex Assembly. J.Cell Biol., 207, 2014
7YUF	apo human SPNS2 分子名称: NbFab H-chain, NbFab L-chain, Sphingosine-1-phosphate transporter SPNS2, ... 著者 He, Y, Duan, Y. 登録日 2022-08-17 公開日 2023-09-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
6ELM	Crystal structure of the human WNK2 CCT1 domain 分子名称: Serine/threonine-protein kinase WNK2 著者 Pinkas, D.M, Bufton, J.C, Newman, J.A, Chalk, R, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. 登録日 2017-09-29 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Crystal structure of the human WNK2 CCT1 domain To Be Published

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