9EOJ
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8VR2
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![BU of 8vr2 by Molmil](/molmil-images/mine/8vr2) | Crystal structure of the Pcryo_0617 oxidoreductase/decarboxylase from Psychrobacter cryohalolentis K5 in the presence of NAD and UDP | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NAD-dependent epimerase/dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Bockhaus, N.J, Thoden, J.B, Holden, H.M. | 登録日 | 2024-01-20 | 公開日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biochemical Investigation of the Enzymes Required for the Production of 2,3,4-triacetoamido-2,3,4-trideoxy-l-arabinose in Psychrobacter cryohalolentis K5 To Be Published
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8VR3
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![BU of 8vr3 by Molmil](/molmil-images/mine/8vr3) | crystal structure of the Pcryo_0618 aminotransferase from Psychrobacter cryohalolentis K5 in the presence of its internal aldimine | 分子名称: | 1,2-ETHANEDIOL, 2,2'-(1,4-diazepane-1,4-diyl)di(ethane-1-sulfonic acid), CHLORIDE ION, ... | 著者 | Bockhaus, N.J, Thoden, J.B, Holden, H.M. | 登録日 | 2024-01-20 | 公開日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biochemical Investigation of the Enzymes Required for the Production of 2,3,4-triacetoamido-2,3,4-trideoxy-l-arabinose in Psychrobacter cryohalolentis K5 To Be Published
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8OUT
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![BU of 8out by Molmil](/molmil-images/mine/8out) | CRYSTAL STRUCTURE OF DLK IN COMPLEX WITH COMPOUND 22 | 分子名称: | (1R)-1-[4-[6-azanyl-5-(trifluoromethyloxy)pyridin-3-yl]-1-(3-fluoranyl-1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]-2,2,2-tris(fluoranyl)ethanol, Mitogen-activated protein kinase kinase kinase 12 | 著者 | Zebisch, M, Akkermans, O, Barker, J.J, Cross, J.B. | 登録日 | 2023-04-24 | 公開日 | 2023-07-26 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.935 Å) | 主引用文献 | Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy. J.Med.Chem., 66, 2023
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6U09
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8YK2
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![BU of 8yk2 by Molmil](/molmil-images/mine/8yk2) | Blood group B alpha-1,3-galactosidase AgaBb from Bifidobacterium bifidum, construct T7-tag_24-700 | 分子名称: | Alpha-galactosidase, GLYCEROL, SODIUM ION, ... | 著者 | Kashima, T, Akama, M, Ashida, H, Fushinobu, S. | 登録日 | 2024-03-04 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structure of Bifidobacterium bifidum Glycoside Hydrolase Family 110 alpha-Galactosidase Specific for Blood Group B Antigen J.Appl.Glyosci., 2024
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8VR5
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![BU of 8vr5 by Molmil](/molmil-images/mine/8vr5) | crystal structure of the Pcryo_0618 aminotransferase from Psychrobacter cryohalolentis K5 in the presence of PMP and glutamate | 分子名称: | 1,2-ETHANEDIOL, 2,2'-(1,4-diazepane-1,4-diyl)di(ethane-1-sulfonic acid), 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Bockhaus, N.J, Thoden, J.B, Holden, H.M. | 登録日 | 2024-01-20 | 公開日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Biochemical Investigation of the Enzymes Required for the Production of 2,3,4-triacetoamido-2,3,4-trideoxy-l-arabinose in Psychrobacter cryohalolentis K5 To Be Published
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7NP5
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![BU of 7np5 by Molmil](/molmil-images/mine/7np5) | ROR(gamma)t ligand binding domain in complex with allosteric ligand FM216 | 分子名称: | 4-[[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrrol-3-yl)-1,2-oxazol-4-yl]methoxy]-2-fluoranyl-benzoic acid, Nuclear receptor ROR-gamma | 著者 | Oerlemans, G.J.M, Somsen, B.A, de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | 登録日 | 2021-02-26 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. J.Med.Chem., 64, 2021
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6XGX
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![BU of 6xgx by Molmil](/molmil-images/mine/6xgx) | ISCth4 transposase, strand transfer complex 1, STC1 | 分子名称: | DNA (21-MER), DNA (25-MER), DNA (47-MER), ... | 著者 | Kosek, D, Dyda, F. | 登録日 | 2020-06-18 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition. Embo J., 40, 2021
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8ZC6
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![BU of 8zc6 by Molmil](/molmil-images/mine/8zc6) | SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with D1F6 Fab, head-to-head aggregate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D1F6 Fab, Light chain of D1F6 Fab, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, Q, He, J, Xiong, X. | 登録日 | 2024-04-28 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (6.85 Å) | 主引用文献 | An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike. Cell Rep, 43, 2024
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7NEC
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![BU of 7nec by Molmil](/molmil-images/mine/7nec) | ROR(gamma)t ligand binding domain in complex with allosteric ligand FM217 | 分子名称: | 4-[[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrrol-2-yl)-1,2-oxazol-4-yl]methoxy]benzoic acid, Nuclear receptor ROR-gamma | 著者 | Somsen, B.A, de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | 登録日 | 2021-02-03 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. J.Med.Chem., 64, 2021
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7NP6
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![BU of 7np6 by Molmil](/molmil-images/mine/7np6) | ROR(gamma)t ligand binding domain in complex with allosteric ligand FM257 | 分子名称: | 4-[[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrazol-4-yl)-1,2-oxazol-4-yl]methoxy]benzoic acid, Nuclear receptor ROR-gamma | 著者 | Oerlemans, G.J.M, Somsen, B.A, de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | 登録日 | 2021-02-26 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. J.Med.Chem., 64, 2021
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9F0E
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8WO0
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![BU of 8wo0 by Molmil](/molmil-images/mine/8wo0) | CryoEM structure of ZIKV rsNS1 filament | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1 | 著者 | Chew, B.L.A, Luo, D. | 登録日 | 2023-10-06 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024
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9BHS
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![BU of 9bhs by Molmil](/molmil-images/mine/9bhs) | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-9939 compound | 分子名称: | (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrole-3-carboxamide, DDB1- and CUL4-associated factor 1, UNKNOWN LIGAND | 著者 | kimani, S, Dong, A, Li, Y, Seitova, A, Al-Awar, R, Wilson, B, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2024-04-21 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-9939 compound To be published
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8WN8
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![BU of 8wn8 by Molmil](/molmil-images/mine/8wn8) | CryoEM structure of ZIKV rsNS1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Non-structural protein 1 | 著者 | Chew, B.L.A, Luo, D. | 登録日 | 2023-10-05 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of Zika virus NS1 multimerization and human antibody recognition Npj Viruses, 2, 2024
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8WO4
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8WNP
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6XPT
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6XPS
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7S6J
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![BU of 7s6j by Molmil](/molmil-images/mine/7s6j) | J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ... | 著者 | Ozorowski, G, Torres, J.L, Ward, A.B. | 登録日 | 2021-09-14 | 公開日 | 2022-05-11 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
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6XWT
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![BU of 6xwt by Molmil](/molmil-images/mine/6xwt) | drosophila melanogaster CENP-A/H4 bound to N-terminal CAL1 fragment | 分子名称: | Chromosome alignment defect 1, Histone H3-like centromeric protein cid, Histone H4 | 著者 | Jeyaprakash, A.A, Medina-Pritchard, B, Lazou, V, Zou, J, Byron, O, Abad, M.A, Rappsilber, J, Heun, P. | 登録日 | 2020-01-24 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.47 Å) | 主引用文献 | Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. Embo J., 39, 2020
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7S6K
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![BU of 7s6k by Molmil](/molmil-images/mine/7s6k) | J08 fragment antigen binding in complex with SARS-CoV-2-6P-Mut2 S protein (conformation 2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, J08 fragment antigen binding heavy chain variable domain, ... | 著者 | Ozorowski, G, Torres, J.L, Ward, A.B. | 登録日 | 2021-09-14 | 公開日 | 2022-05-11 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody. Proc.Natl.Acad.Sci.USA, 119, 2022
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6TZQ
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7ZBD
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![BU of 7zbd by Molmil](/molmil-images/mine/7zbd) | HaloTag with TRaQ-G ligand | 分子名称: | (10R)-7-azanyl-N-[2-[2-(6-chloranylhexoxy)ethoxy]ethyl]-2'-cyano-5,5-dimethyl-3-(methylamino)-1'-oxidanylidene-spiro[benzo[b][1]benzosiline-10,3'-isoindole]-5'-carboxamide, CHLORIDE ION, GLYCEROL, ... | 著者 | Emmert, S, Rivera-Fuentes, P, Pojer, F, Lau, K. | 登録日 | 2022-03-23 | 公開日 | 2023-02-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | A locally activatable sensor for robust quantification of organellar glutathione. Nat.Chem., 15, 2023
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